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Stable RNA synthesis and its control in Mycoplasma capricolum.

Abstract：

:The synthesis of stable RNA in Mycoplasma capricolum was studied by [32P] labeling of cellular RNA of cells grown in a partially-defined medium in the presence or absence of an amino acid mixture supplement. The results indicate that M. capricolum employs the same stringent control mechanism used by E. coli cells, as judged by a decreased synthesis of stable RNA and accumulation of 5'-triphosphoguanosine-3'-diphosphate (pppGpp) and 5'-diphosphoguanosine-3'-diphosphate (ppGpp) in response to amino acid starvation. In addition, the results suggest that precursors of stable RNA accumulate and an intracellular pool of the precursors exists at all times under the growth conditions used by us. These findings may be interpreted to reflect a slow rate of RNA processing in M. capricolum.

journal_name

Nucleic Acids Res

journal_title

Nucleic acids research

authors

Glaser G,Razin A,Razin S

doi

10.1093/nar/9.15.3641

subject

Has Abstract

pub_date

1981-08-11 00:00:00

pages

3641-6

issue

15

eissn

0305-1048

issn

1362-4962

journal_volume

9

pub_type

杂志文章

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