Deoxycytidine triphosphate deaminase: characterization of an Escherichia coli mutant deficient in the enzyme.

Abstract:

:A mutant of Escherichia coli, previously shown to contain abnormal nucleoside triphosphate pools, was found to be defective in its ability to synthesize thymidine nucleotides. The defect is not in the enzyme thymidylate synthetase but in deoxycytidine triphosphate deaminase, an enzyme that supplies deoxyuridine monophosphate, the substrate for thymidylate synthetase.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

O'Donovan GA,Edlin G,Fuchs JA,Neuhard J,Thomassen E

doi

10.1128/JB.105.2.666-672.1971

subject

Has Abstract

pub_date

1971-02-01 00:00:00

pages

666-72

issue

2

eissn

0021-9193

issn

1098-5530

journal_volume

105

pub_type

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