Structure-based functional analysis of the replication protein of plasmid R6K: key amino acids at the pi/DNA interface.

Abstract:

:In previous work, we characterized the bases in an iteron of plasmid R6K that are important for the binding of pi protein monomers and dimers. Here we investigate the following six amino acids of pi, encoded by pir, hypothesized to be important for DNA contact: Ser71, Try74, Gly131, Gly211, Arg225, and Arg254.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Kunnimalaiyaan S,Rakowski SA,Filutowicz M

doi

10.1128/JB.00109-07

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

4953-6

issue

13

eissn

0021-9193

issn

1098-5530

pii

JB.00109-07

journal_volume

189

pub_type

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