Abstract:
:The effect of dose and duration of treatment with chromium on its distribution in certain vital organs and the blood of rats has been investigated. The accumulation of metal was highest in liver and kidneys, followed by testes, brain and blood and was rather more dependent on the dose than on the duration of exposure. The sub-cellular distribution in liver revealed greater concentration of the metal in the nuclear fraction than in the mitochrondrial or the post mitochondrial fraction. The uptake of the metal by the mitochondrial fraction however, increased with the increase in the dose of chromium from 1 mg/kg to 2 or 3 mg/kg.
journal_name
Toxicologyjournal_title
Toxicologyauthors
Tandon SK,Behari JR,Kachru DNsubject
Has Abstractpub_date
1979-05-01 00:00:00pages
29-34issue
1eissn
0300-483Xissn
1879-3185journal_volume
13pub_type
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