Abstract:
:The radiation dose to the pulp of both index fingers has been measured in a radiopharmacy supplying 11 000 patient doses a year, in a hospital dispensary (4500 doses a year) and in its injection area. Tungsten syringe shields were used for one week and not used during the other week. In the radiopharmacy and the dispensary the highest finger dose recorded was 6.8 mSv, which corresponds to an annual figure of 330 mSv. Syringe shields gave a protection factor of less than two, and the dose to the left hand was approximately half that to the right. When giving injections the corresponding weekly and annual doses were 4.6 and 220 mSv respectively. If all injections had been given by a single person the corresponding annual dose would have been 430 mSv. Using syringe shields this could be reduced by factors of at least eight for the right hand but only 1.3 for the left hand. Dose rates for unshielded syringes expressed per 10 GBq handled are similar to other data in the literature. However, syringe shields reduce the dose rates less than anticipated. Tungsten 1.94 to 3.05 mm thick would be expected to give an attenuation factor of 27 to 178.
journal_name
Nucl Med Communjournal_title
Nuclear medicine communicationsauthors
Harding LK,Hesslewood S,Ghose SK,Thomson WHdoi
10.1097/00006231-198508000-00004subject
Has Abstractpub_date
1985-08-01 00:00:00pages
449-54issue
8eissn
0143-3636issn
1473-5628journal_volume
6pub_type
杂志文章abstract:BACKGROUND:A new kinetic model of technetium-99m-labeled diethylenetriaminepentaacetic acid-galactosyl human serum albumin (Tc-GSA) was developed to show the speed of asialoglycoprotein receptor-mediated endocytosis. MATERIALS AND METHODS:Ten healthy volunteers and 17 patients with liver cirrhosis were intravenously i...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e328362e7c7
更新日期:2013-09-01 00:00:00
abstract::Liver metastasis is a common consequence of colorectal carcinoma. Early and accurate detection of liver metastasis is crucial for a decision about partial hepatectomy, which is considered a standard and potentially curative therapy in such a setting. The presence of extrahepatic metastases will exclude surgical resect...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200009000-00002
更新日期:2000-09-01 00:00:00
abstract::The advent of PET instrumentation signaled the beginning of a new perspective in nuclear medicine diagnostic imaging. PET systems rely on several corrections that must be applied in order to establish accurate and reliable quantification. The inherent properties of PET detector architecture and the crystals themselves...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,评审
doi:10.1097/MNM.0b013e328365ac1e
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:Radioiodine ablation of thyroid tissue remains the cornerstone of treatment for patients with differentiated thyroid carcinoma after thyroidectomy. Selecting an optimal dose of radioiodine for successful ablation is a continuous challenge in these patients. METHODS:We compared the treatment response of 341 ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章,随机对照试验
doi:10.1097/MNM.0b013e32834e306a
更新日期:2012-03-01 00:00:00
abstract::Equilibrium radionuclide angiography (ERNA) is the 'gold standard' for assessing left ventricular ejection fraction (LVEF). The aim of the study was to determine whether the left ventricular cavity-to-myocardium count ratio (LVCMR) from 201Tl myocardial single photon emission computed tomography (SPECT) correlated wit...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-200103000-00004
更新日期:2001-03-01 00:00:00
abstract::Simultaneous assessment of regional adrenergic activity and perfusion with 123I-meta-iodobenzylguanidine (123I-MIBG) and 201Tl in various organs was performed in 13 patients with congestive heart failure (CHF) and 13 subjects without heart failure. In order to reduce the crosstalk of 201Tl to the 123I energy window to...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199603000-00009
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:To assess the ability of Ga DOTA-NOC PET/computed tomography (CT) to differentiate dural metastases from meningioma. PATIENTS AND METHODS:Patients who underwent a Ga DOTA-NOC PET/CT for differentiating meningiomas from dural metastases were included in the study. A visual score was assigned to the dural lesi...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001155
更新日期:2020-04-01 00:00:00
abstract::Technetium-99m (99Tcm)(V) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent which has been used to evaluate squamous carcinoma (SCC) of the head and neck. This study evaluated the pharmacokinetics and biodistribution of 99Tcm(V)DMSA in patients with SCC and calculated the bone mass of a New Zealand White (N...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199005000-00002
更新日期:1990-05-01 00:00:00
abstract::A non-invasive technique for the assessment of hepatic haemodynamics using radiocolloid imaging with a computer, in which absolute values of hepatic, mesenteric and splenic arterial effective blood flows were assessed, is described. The technique was carried out on ten volunteers, before and after a standard meal. Aft...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198708000-00002
更新日期:1987-08-01 00:00:00
abstract:OBJECTIVES:The determination of lesion boundaries on FDG PET is difficult due to the point-spread blurring and unknown uptake of activity within a lesion. Standard threshold-based methods for volumetric quantification on PET usually neglect any size dependence and are biased by dependence on the signal-to-background ra...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e328155d154
更新日期:2007-06-01 00:00:00
abstract::The aim of this study was to compare 99Tcm-teboroxime and 201T1 myocardial studies with particular regard to the classification of perfusion defects as reversible or fixed. Twenty patients with a history of previous myocardial infarction and suspected effort ischaemia underwent exercise 201T1 scintigraphy with early (...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199307000-00002
更新日期:1993-07-01 00:00:00
abstract:OBJECTIVE:To verify the negative predictive value of pulmonary ventilation/perfusion scintigraphy with single photon emission computed tomography (V/Q SPECT) in ruling out pulmonary thromboembolism. METHODS:V/Q SPECT using 99mTc-Technegas was performed on 584 patients to rule out pulmonary thromboembolism between Octo...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/MNM.0b013e32827a8e99
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:Easy large-scale production, easy availability, cost-effectiveness, long half-life, and favorable radiation characteristics have made lutetium-177 (Lu) a preferred radionuclide for use in therapy. Lutetium-177-labeled stannous (Lu-Sn) colloid particles were formulated for application in radiosynovectomy, foll...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000684
更新日期:2017-07-01 00:00:00
abstract::We evaluated the clinical usefulness of 99Tcm-N,N-ethylenedicysteine (99Tcm-EC), a new renal tubular agent, in normal children and in children with various renal disorders and compared it with 99Tcm-mercaptoacetyltriglycine (99Tcm-MAG3). In a first group of children (Group 1), which included 15 patients and 4 normal c...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199701000-00009
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:We estimated the absorbed doses for (111)In-DTPA-D-Phe(1)-octreotide and (90)Y-DOTA-D-Phe(1)-Tyr(3)-octreotide in the same patients in order to compare the potential effectiveness (tumour dose) and safety (kidney and red marrow dose) of these drugs for peptide-targeted radiotherapy of somatostatin receptor po...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e3282f3d03e
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:The present study evaluated the usefulness of postoperative fluorine-18 fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) in the management of olfactory neuroblastoma (ONB). MATERIALS AND METHODS:Ten patients (eight men and two women; mean age, 48.5 years) with histologically confirmed ONB who underwent ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000135
更新日期:2014-08-01 00:00:00
abstract::A comparative study of bone marrow scintigraphy using 99Tcm-nanocolloid, conventional bone scintigraphy and bone marrow biopsy were performed in 35 patients with histologically proven small cell carcinoma of the lung to determine whether bone marrow scintigraphy has a role in the early detection of bone marrow metasta...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199401000-00006
更新日期:1994-01-01 00:00:00
abstract::Single photon emission computed tomography (SPECT) imaging of dopamine transporters by using the cocaine derivative [123I]-(1R)-2-beta-carbomethoxy-3-beta-(4-iodophenyl)-tropane ([123I]-beta-CIT) has been shown to be useful in patients with Parkinsonism. The aim of this study was to compare beta-CIT imaging with singl...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200102000-00005
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:The aim of our study was to explore the value of 3'-deoxy-3'-[F]fluorothymidine (F-FLT) and F-FLT PET in monitoring the early biologic response of esophageal carcinoma after irradiation in vitro and in vivo. METHODS:After 2, 4, and 8 h of irradiation at different doses (0, 5, 10, and 15 Gy) of esophageal car...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000201
更新日期:2014-12-01 00:00:00
abstract::This paper describes in vitro cytotoxicity experiments with 213Bi- and 225Ac-immunoconjugates on the human epidermoid tumour cell line A431 using a blood group A-reactive murine IgG (2D11) as the specific antibody and MOPC 21 as the control antibody. With both radionuclides, specific cell-killing was achieved. The obs...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199506000-00009
更新日期:1995-06-01 00:00:00
abstract::21 patients with Wolff-Parkinson-White (WPW) syndrome were investigated through radionuclide imaging and body surface mapping. Ventricular preexcitation was localized by display of identical phase ventricular regions (phase display). In 79% of the cases radioisotope and body surface mapping methods have identical resu...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198607000-00004
更新日期:1986-07-01 00:00:00
abstract:AIM:The aim of our study was to assess improvements in spatial resolution and noise control from the application of the Astonish resolution recovery algorithm for single photon emission computed tomography imaging. Secondary aims were to compare acquisitions made with low-energy general purpose collimators with those o...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0b013e32835ce5b5
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to assess the diagnostic and prognostic value of fluorine-18-fluorodeoxyglucose (F-FDG) PET/CT in patients with breast cancer (BC) in the preoperative and the postoperative setting. PATIENTS AND METHODS:Between 2011 and 2015, we prospectively enrolled 275 patients (mean age: 53 years)...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000671
更新日期:2017-06-01 00:00:00
abstract::We performed in vitro aggregation and indium-111 labeled platelet kinetic and biodistribution studies in seven patients with diabetes mellitus and in five control subjects. All subjects were male. All diabetic patients were poorly controlled at the time of study with blood glucose greater than 140 mg % and hemoglobin ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198803000-00006
更新日期:1988-03-01 00:00:00
abstract:PURPOSE:Patient-specific dosimetry of lutetium-177 ((177)Lu)-DOTATATE treatment in neuroendocrine tumours is important, because uptake differs across patients. Single photon emission computer tomography (SPECT)-based dosimetry requires a conversion factor between the obtained counts and the activity, which depends on t...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000000079
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the success rate in lymphatic mapping and sentinel node biopsy in breast cancer using two radiopharmaceuticals. METHODS:The study included 119 breast cancer patients who underwent lymphoscintigraphy after a single intratumoral injection of 99mTc-labelled human albumin co...
journal_title:Nuclear medicine communications
pub_type: 临床试验,杂志文章
doi:10.1097/00006231-200403000-00004
更新日期:2004-03-01 00:00:00
abstract::First pass radionuclide angiocardiography (FPRNA) has gained increasing interest because of the development of new 99Tcm-labelled perfusion agents and of new 191Os/191Irm generator systems. The aim of the study was to evaluate the performance capacities of a small field of view single crystal digital gamma camera for ...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199101000-00004
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the diagnostic value of fluorodeoxyglucose-18 (FDG)-PET/computed tomography (CT) and MRI parameters in determining the molecular subtypes of invasive breast cancer. METHODS:Data from 55 primary invasive breast cancer masses in 51 female patients who underwent pre-treat...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/MNM.0000000000001220
更新日期:2020-08-01 00:00:00
abstract::Thirty patients with aortic valve incompetence and 21 control subjects were examined by M-mode echocardiography at rest and radionuclide ventriculography during submaximal handgrip exercise. The patients had greater left ventricular dimensions and end-systolic wall stress values but peak systolic wall stress values di...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-199004000-00004
更新日期:1990-04-01 00:00:00
abstract::Following injection for renography, 99Tcm-labelled diethylenetriamine-pentacetic acid (DTPA) rapidly enters the extravascular space. Background therefore comprises two components, a falling intravascular signal and an extravascular signal which initially rises. We estimated the relative magnitudes of these two compone...
journal_title:Nuclear medicine communications
pub_type: 杂志文章
doi:10.1097/00006231-198808000-00003
更新日期:1988-08-01 00:00:00