Evaluation of 99Tcm-teboroxime scintigraphy for the differentiation of reversible from fixed defects: comparison with 201T1 redistribution and reinjection imaging.

Abstract:

:The aim of this study was to compare 99Tcm-teboroxime and 201T1 myocardial studies with particular regard to the classification of perfusion defects as reversible or fixed. Twenty patients with a history of previous myocardial infarction and suspected effort ischaemia underwent exercise 201T1 scintigraphy with early (4 h) redistribution and reinjection scans, exercise and rest 99Tcm-teboroxime imaging and coronary angiography. Using a qualitative scoring of static planar images, the perfusion defects were classified as reversible or fixed. 201T1 and 99Tcm-teboroxime gave comparable results in the evaluation of the individual vessels (sensitivity 65%, specificity 80% and 85%, respectively). The stress-redistribution 201T1 sequence classified 45 defects as reversible and 28 as fixed, the stress-rest 99Tcm-teboroxime studies classified 47 as reversible and 26 as fixed (NS). The stress-reinjection 201T1 images, however, characterized 64 defects as reversible and nine as fixed (P < 0.005 versus 201T1 redistribution, P < 0.0005 versus 99Tcm-teboroxime rest). In conclusion, this study shows that rest 99Tcm-teboroxime and 201T1 redistribution give comparable results but that significantly more defects are classified as fixed by 99Tcm-teboroxime than by 201T1 if reinjection of the latter tracer is performed.

journal_name

Nucl Med Commun

authors

Bisi G,Sciagrà R,Santoro GM,Zerauschek F,Fazzini PF

doi

10.1097/00006231-199307000-00002

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

520-8

issue

7

eissn

0143-3636

issn

1473-5628

journal_volume

14

pub_type

杂志文章
  • A routine method for using sodium iodide to stabilize sodium pertechnetate [99Tcm] dispensed for the preparation of 99Tcm-exametazime.

    abstract::When preparing 99Tcm-exametazime, it is important to use sodium 99Tcm-pertechnetate that is less than 2 h old. The addition of sodium iodide (NaI) to 99Tcm-pertechnetate is known to extend this time to 6 h. This paper describes a technique for implementing this in routine practice. Sterile kits consisting of 440 micro...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199205000-00003

    authors: Millar AM

    更新日期:1992-05-01 00:00:00

  • Image-derived input function in PET brain studies: blood-based methods are resistant to motion artifacts.

    abstract:BACKGROUND:Image-derived input function (IDIF) from carotid arteries is an elegant alternative to full arterial blood sampling for brain PET studies. However, a recent study using blood-free IDIFs found that this method is particularly vulnerable to patient motion. The present study used both simulated and clinical [11...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e328356185c

    authors: Zanotti-Fregonara P,Liow JS,Comtat C,Zoghbi SS,Zhang Y,Pike VW,Fujita M,Innis RB

    更新日期:2012-09-01 00:00:00

  • Detection of norepinephrine distribution in rats with adrenal medulla autotransplants using 125I-meta-iodobenzyl guanidine.

    abstract::The viability of autologous adrenal medullary transplants was evaluated using 125I-meta-iodobenzyl guanidine (MIBG), an adrenal medullary scanning agent. Bilateral cavities in the caudate nuclei were made stereotaxically in Wistar rats. One week later, the left adrenal medulla was resected by microsurgery, followed by...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199409000-00015

    authors: Shinoda M,Suzuki Y,Oi S,Tsugane R,Sato O

    更新日期:1994-09-01 00:00:00

  • Occurrence of pulmonary thromboembolism immediately after arthroplasty.

    abstract:INTRODUCTION:Respiratory complications are common after arthroplasty, with pulmonary thromboembolic disease (PTE) and fat emboli being the most serious. A scintigraphic study was designed to assess the occurrence of both diseases. A prospective tomographic study of perfusion was performed within 24 h of arthroplasty. D...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200111000-00011

    authors: Bruce W,Van der Wall H,Peters M,Liaw Y,Morgan L,Storey G

    更新日期:2001-11-01 00:00:00

  • Dosimetric evaluation and therapeutic response to internal radiation therapy of hepatocarcinomas using iodine-131-labelled lipiodol.

    abstract:OBJECTIVE:Vectorized internal radiation therapy using lipiodol-labelled with iodine-131 (131 I-lipiodol) is an effective treatment for inoperable hepatocellular carcinomas. However, few dosimetric data are available based on this approach. We have developed a dosimetric protocol based on scintiscan imaging and that is ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e32830439c6

    authors: Becker S,Laffont S,Vitry F,Rolland Y,Lecloirec J,Boucher E,Raoul JL,Herry JY,Bourguet P,Garin E

    更新日期:2008-09-01 00:00:00

  • 131 I-cG250 monoclonal antibody immunoscintigraphy versus [18 F]FDG-PET imaging in patients with metastatic renal cell carcinoma: a comparative study.

    abstract::The aims of this study were to establish the percentage of metastatic renal cell carcinoma (RCC) lesions detected by radioimmunoscintigraphy (RIS) with the chimeric monoclonal antibody 131I-cG250 versus positron emission tomography (PET) with 18F-labelled deoxyglucose ([18F]FDG), and to evaluate the use of these radio...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200203000-00005

    authors: Brouwers AH,Dorr U,Lang O,Boerman OC,Oyen WJ,Steffens MG,Oosterwijk E,Mergenthaler HG,Bihl H,Corstens FH

    更新日期:2002-03-01 00:00:00

  • Prognostic value of quantitative PET/CT in patients with a nonsmall cell lung cancer and another primary cancer.

    abstract:OBJECTIVE:The staging and management of patients with newly diagnosed nonsmall cell lung cancer (NSCLC) in the setting of recently diagnosed other (metachronous or synchronous) primary cancer are challenging. This retrospective cohort study was carried out to test our hypothesis that baseline 2-deoxy-2-[F]fluoro-D-gluc...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000627

    authors: Zhu X,Liao C,Penney BC,Li F,Ferguson MK,Simon CA,Wu T,Liu H,Pu Y

    更新日期:2017-02-01 00:00:00

  • Pulmonary perfusion assessment with respiratory gated 99mTc macroaggregated albumin SPECT: preliminary results.

    abstract:PURPOSE:Respiratory gated perfusion single photon emission computed tomography (SPECT) was applied to reduce respiratory lung motion effects and to reliably assess perfusion impairment in various lung diseases. METHODS:After injection of 259 MBq of 99mTc macroaggretated albumin (99mTc-MAA), gating was performed using ...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/00006231-200402000-00016

    authors: Suga K,Kawakami Y,Zaki M,Yamashita T,Matsumoto T,Matsunaga N

    更新日期:2004-02-01 00:00:00

  • Comparison of treatment efficacy 1 and 2 years after thyroid remnant ablation with 1110 versus 5550 MBq of iodine-131 in patients with intermediate-risk differentiated thyroid cancer.

    abstract:BACKGROUND:Radioiodine ablation may be associated with improved survival in patients with intermediate-risk follicular cell differentiated thyroid cancer (FCDTC). The aim of this study was to compare ablation efficacy of 1110 versus 5500 MBq of iodine-131 (I) in FCDTC patients with intermediate risk. METHODS:Thirty-ni...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000730

    authors: Aghaei A,Ayati N,Shafiei S,Abbasi B,Zakavi SR

    更新日期:2017-11-01 00:00:00

  • Predicting the response to cardiac resynchronization therapy using 99mTc-tetrofosmin myocardial scintigraphy in patients with drug-refractory heart failure: additional value of the washout of 99mTc-tetrofosmin.

    abstract:OBJECTIVE:A lack of response to cardiac resynchronization therapy (CRT) has been reported in 20-40% of heart failure patients with left ventricular (LV) dyssynchrony who underwent treatment based on the established guidelines. The study aimed to investigate the relationship between (99m)Tc-tetrofosmin ((99m)Tc-TF) myoc...

    journal_title:Nuclear medicine communications

    pub_type: 临床试验,杂志文章

    doi:10.1097/MNM.0000000000000150

    authors: Shigeru M,Fujiwara S,Takamine S,Yoshida A,Kawai H,Shiotani H,Hirata K

    更新日期:2014-09-01 00:00:00

  • Right ventricular thallium-201 visualization in hypertrophic cardiomyopathy.

    abstract::Fifty-six patients with hypertrophic cardiomyopathy who had echocardiography and cardiac catheterization were studied. Eleven (18%) of 56 patients had right ventricular (RV) thallium-201 visualization at resting scan. RV thallium-201 visualization was observed in the apex or lower half of the RV free wall, which was q...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Nishimura T,Uehara T,Hayashida K,Nagata S

    更新日期:1988-01-01 00:00:00

  • Evaluation of motion-correction methods for dual-gated cardiac positron emission tomography/computed tomography imaging.

    abstract:BACKGROUND:Dual gating is a method of dividing the data of a cardiac PET scan into smaller bins according to the respiratory motion and the ECG of the patient. It reduces the undesirable motion artefacts in images, but produces several images for interpretation and decreases the quality of single images. By using motio...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000539

    authors: Klén R,Noponen T,Koikkalainen J,Lötjönen J,Thielemans K,Hoppela E,Sipilä H,Teräs M,Knuuti J

    更新日期:2016-09-01 00:00:00

  • 201T1 and 99Tcm-J001X macrophage scintigraphy: two radionuclide imaging techniques for the surveillance of acute localized radiation over-exposures.

    abstract::The therapeutic or surgical management of acute localized irradiation is very complicated due to the delayed occurrence of ionizing radiation effects. There is a great need for non-invasive imaging techniques to delineate healthy from exposed tissues. Such a technique should be of value considering that spread of dama...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:

    authors: Perin F,Pittet JC,Hoffschir D,Daburon F,Normier G,Le Pape A

    更新日期:1995-07-01 00:00:00

  • Nuclear cardiology in the UK: British Nuclear Cardiology Society survey 1994.

    abstract::This study surveyed practice in nuclear cardiology in the UK in 1994. A questionnaire was sent to 219 centres performing nuclear imaging asking for details of current practice in nuclear cardiology. Replies were received from 192 centres (88%). Activity in performance of myocardial perfusion imaging (MPI) and radionuc...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199804000-00004

    authors: Pennell DJ,Prvulovich E,Tweddel A,Caplin J

    更新日期:1998-04-01 00:00:00

  • Pre-surgical identification of epileptogenic areas in temporal lobe epilepsy by 123I-iomazenil SPECT: a comparison with IMP SPECT and FDG PET.

    abstract:OBJECTIVES:The aim of this study was to evaluate the usefulness of (123)I-iomazenil (IMZ) single photon emission computed tomography (SPECT) for the pre-surgical identification of epileptogenic areas in patients with temporal lobe epilepsy and to compare the results with those of (123)I-IMP SPECT and (18)Fluorodeoxyglu...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/01.mnm.0000243380.79872.32

    authors: Kaneko K,Sasaki M,Morioka T,Koga H,Abe K,Sawamoto H,Ohya N,Yoshiura T,Mihara F,Honda H

    更新日期:2006-11-01 00:00:00

  • Use of insulin to improve [18 F]fluorodeoxyglucose labelling and retention for in vivo positron emission tomography imaging of monocyte trafficking.

    abstract::While 18F-FDG labelling of monocytes would allow in vivo trafficking with positron emission tomography (PET), present methods suffer from poor retention of radioactivity. We investigated the feasibility of utilizing insulin for improved [18F]fluorodeoxyglucose (18F-FDG) labelling. Separated human monocytes and lymphoc...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200206000-00007

    authors: Paik JY,Lee KH,Byun SS,Choe YS,Kim BT

    更新日期:2002-06-01 00:00:00

  • In vivo evaluation of three different 99mTc-labelled radiopharmaceuticals for sentinel lymph node identification.

    abstract::This work was designed to compare sentinel lymph node (SLN) uptake of 99mTc-labelled human serum albumin colloid (99mTc-HSAC), 99mTc-labelled antimony sulphur colloid (99mTc-SC) and a 99mTc-labelled dextran 70 solution (99mTc-Dx) and their selectivity in the identification of this node in the right rear footpad (RRF) ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200105000-00006

    authors: Edreira MM,Colombo LL,Perez JH,Sajaroff EO,de Castiglia SG

    更新日期:2001-05-01 00:00:00

  • Correlation of 99Tcm-sestamibi SPECT with coronary angiography in general hospital practice.

    abstract::One hundred and twenty-eight patients had a stress test with sestamibi injection and a coronarography within 2 months of the sestamibi study. Sestamibi studies were reconstructed using Hanning 0.65 and Wiener 1.0 filters; the latter improved the results significantly (P < 0.05). Significant correlations were found bet...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199301000-00006

    authors: Solot G,Hermans J,Merlo P,Chaudron JM,Luwaert R,Cheron P,Bodart F,Beauduin M

    更新日期:1993-01-01 00:00:00

  • Influence of statistical noise on the determination of the single kidney 99Tcm-DTPA clearance.

    abstract::Single kidney clearance can be obtained using the 99Tcm-DTPA complex and the scintillation camera. In order to evaluate the influence of statistical noise on the determination of the clearance, several non-noisy curves were constructed, simulating renal, background and precordial curves. Poisson noise was added to the...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198508000-00008

    authors: Piepsz A,Dobbeleir A,Ham HR

    更新日期:1985-08-01 00:00:00

  • Semi-quantitative assessment of 99Tcm-sestamibi uptake in lung cancer: relationship with clinical response to chemotherapy.

    abstract::The objectives of this study were to measure semi-quantitatively uptake of 99Tcm-sestamibi (99Tcm-MIBI) by tumour tissue in patients with lung cancer and to investigate its relationship with clinical response to chemotherapy. 99Tcm-MIBI single photon emission tomography was performed at the time of diagnosis in 31 pat...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199711000-00013

    authors: Ceriani L,Giovanella L,Bandera M,Beghe B,Ortelli M,Roncari G

    更新日期:1997-11-01 00:00:00

  • Prevalence and quantitative analysis of indium-111 pentetreotide (Octreoscan) uptake in the pancreatic head on SPECT/CT imaging: establishing a region of interest-based pathological uptake threshold.

    abstract:OBJECTIVE:Determine the prevalence of benign indium-111 (In) pentetreotide uptake in the pancreatic head and determine if a semi-quantitative method can be used to differentiate physiologic from pathologic uptake. PATIENTS AND METHODS:Institutional Review Board-approved, HIPAA-compliant retrospective review of 197 som...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000001022

    authors: Derakhshan JJ,Farwell MD

    更新日期:2019-07-01 00:00:00

  • Radioimmunoguided surgery of colorectal carcinoma with an 111In-labelled anti-TAG72 monoclonal antibody.

    abstract::Radioimmunoscintigraphy (RIS) and radioimmunoguided surgery (RIGS) were assessed for their usefulness in patients with colorectal carcinoma. Twenty-nine patients (18 primary tumours, 10 with a suspicion of recurrence and one colonic diverticulitis) were studied. Radioimmunoscintigraphy was performed 48 and 72 h after ...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199902000-00003

    authors: Muxi A,Pons F,Vidal-Sicart S,Setoain FJ,Herranz R,Novell F,Fernandez RM,Trias M,Setoain J

    更新日期:1999-02-01 00:00:00

  • Estimation of patient attenuation factor for iodine-131 based on direct dose rate measurements from radioiodine therapy patients.

    abstract::The aim of the study was to measure the actual dose at 1 m from the patients per unit activity with the aim of providing a more accurate prediction of the dose levels around radioiodine patients in the hospital, as well as to compare our results with the literature. In this work the demonstration of a patient body tis...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0000000000000223

    authors: Soliman K,Alenezi A

    更新日期:2015-02-01 00:00:00

  • Comparison of methods for quantification of transient ischaemic dilation in myocardial perfusion SPET.

    abstract::The purpose of this study was to compare six methods of measuring the left ventricular (LV) transient ischaemic dilation (TID) ratio during stress-rest myocardial perfusion single-photon emission tomography (SPET). The TID ratio was defined as the mean LV short-axis area at stress divided by the mean LV area of simila...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-200010000-00013

    authors: Peace RA,McKiddie FI,Staff RT,Gemmell HG

    更新日期:2000-10-01 00:00:00

  • Spontaneous variability of left ventricular ejection fraction assessed with the Cardioscint.

    abstract::A miniature, non-imaging caesium iodide nuclear probe optically coupled to a photodiode (the 'Cardioscint') has been developed which, in conjunction with a modified personal computer, is capable of continuous on-line monitoring of left ventricular function and ST-segment level at the bedside. The purpose of this study...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199205000-00004

    authors: Broadhurst P,Liu XJ,Cashman PM,Raftery EB,Lahiri A

    更新日期:1992-05-01 00:00:00

  • 99Tcm-MIBI single photon emission tomography (SPET) for detecting myocardial ischaemia and necrosis in patients with significant coronary artery disease.

    abstract::The ability of 99Tcm-methoxyisobutylisonitrile (MIBI) single photon emission tomography (SPET) to detect myocardial ischaemia and necrosis was assessed in 56 patients (45 male, 11 female, aged 55 +/- 5 years), with clinically recognized ischaemic heart disease (IHD). All underwent coronary angiography (CA) and left ve...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-199212000-00004

    authors: Sciammarella MG,Fragasso G,Gerundini P,Maffioli L,Cappelletti A,Margonato A,Savi A,Chierchia S

    更新日期:1992-12-01 00:00:00

  • Appropriate selection of background for 99Tcm-DTPA renography.

    abstract::Since 99Tcm-DTPA is diffusible and not significantly protein bound in plasma, it rapidly enters the extravascular space following injection. Therefore, during the first few minutes of the DTPA renogram, the period on which the measurements of individual kidney glomerular filtration rate and differential function are b...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198812000-00006

    authors: Peters AM,George P,Ballardie F,Gordon I,Todd-Pokropek A

    更新日期:1988-12-01 00:00:00

  • Radiolytic breakdown of sodium iodide (131I) in sodium iodide (131I) capsules.

    abstract::Sodium iodide (131I) capsules are widely used for both diagnosis and therapy. The radiochemical purity of both diagnostic and therapeutic capsules in use in Australia was studied by gel chromatography, high voltage electrophoresis and paper chromatography. It was found that in two of the three bands of therapeutic cap...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/00006231-198611000-00007

    authors: Bonnyman J,Van Every B

    更新日期:1986-11-01 00:00:00

  • Evaluation of reconstruction techniques for lung single photon emission tomography: a Monte Carlo study.

    abstract:BACKGROUND:In studies of the distribution of lung function, the image quality of lung single photon emission computed tomography (SPECT) is important and one factor influencing it is the reconstruction algorithm. AIM:To systematically evaluate ordered subsets expectation maximization (OSEM) and compare it with filtere...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e3282f1acac

    authors: Norberg P,Bake B,Jacobsson L,Carlsson GA,Gustafsson A

    更新日期:2007-12-01 00:00:00

  • Comparison of 123I-MIBG SPECT-CT and 18F-DOPA PET-CT in the evaluation of patients with known or suspected recurrent paraganglioma.

    abstract:OBJECTIVES:Detection of recurrent disease is essential for treatment planning in patients with paraganglioma. The aim of this study was to compare 123I-metaiodobenzylguanidine (123I-MIBG) scintigraphy [whole-body and single-photon emission computed tomography (SPECT) computed tomography (CT) scanning] and fluorine-18-L...

    journal_title:Nuclear medicine communications

    pub_type: 杂志文章

    doi:10.1097/MNM.0b013e328345a340

    authors: Rufini V,Treglia G,Castaldi P,Perotti G,Calcagni ML,Corsello SM,Galli G,Fanti S,Giordano A

    更新日期:2011-07-01 00:00:00