Abstract:
:Daily early morning urine samples were collected from women receiving donor artificial insemination and were evaluated for estrone conjugates, pregnanediol-3-glucuronide, and human chorionic gonadotropin. All hormone concentrations in urine were indexed by creatinine levels and expressed as the concentration of hormone per milligram creatinine. Composite profiles of 23 women who conceived normal full-term pregnancies were compared with composite profiles obtained from 11 of the same women during nonconception cycles. The endocrine profiles of seven pregnancies that spontaneously aborted and two ectopic pregnancies were also evaluated retrospectively. The combined application of these three urinary hormone indices provides a practical approach for prospective monitoring of the major hormone dynamics during ovulation and implantation and during relatively infrequent events such as spontaneous abortion and ectopic pregnancy. The rise of estrone conjugates which precedes detectable increases of urinary human chorionic gonadotropin at the time of implantation appears to be an early indicator of implantation and may prove to be the best method for detection of occult pregnancy. This method is also suitable for monitoring early pregnancy when exogenous gonadotropins have been employed, as in embryo transfer following in vitro fertilization.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Lasley BL,Stabenfeldt GH,Overstreet JW,Hanson FW,Czekala N,Munro Cdoi
10.1016/s0015-0282(16)48613-9subject
Has Abstractpub_date
1985-06-01 00:00:00pages
861-7issue
6eissn
0015-0282issn
1556-5653pii
S0015-0282(16)48613-9journal_volume
43pub_type
杂志文章abstract:OBJECTIVE:To investigate whether women who conceive after assisted reproductive technology (ART) are at higher risk for emergency peripartum hysterectomy. DESIGN:A case-control study using a prospectively maintained institutional database. SETTING:A tertiary referral university teaching maternity hospital. PATIENT(S...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.05.005
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To investigate whether temporarily withholding FSH and adding androgen could improve follicular response during a microdose flare protocol in women with slow follicular growth or asynchronous follicular development. DESIGN:Observational pilot study. SETTING:University-affiliated private fertility center. P...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.09.038
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:To determine whether NR5A1 (SF-1) variants are a cause of primary ovarian insufficiency (POI) in 26 young women with similar genetic background. DESIGN:Genetic and functional mutation study. SETTING:University hospitals. PATIENT(S):Genetic analysis of the NR5A1 gene in 26 XX girls with POI. INTERVENTION(S...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2012.10.026
更新日期:2013-02-01 00:00:00
abstract::A case is described in which, after a tubal sterilization procedure and subsequent unilateral tubal anastomosis, an ectopic gestation occurred in the contralateral, unrepaired, distal tubal segment. On the basis of this case and related evidence, the authors suggest that in cases in which only a unilateral tubal anast...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59068-2
更新日期:1987-03-01 00:00:00
abstract:OBJECTIVE:To study the in vivo mechanisms of action of ulipristal acetate (UPA) on uterine myomas. DESIGN:Retrospective histologic and immunohistochemical (IHC) study of myomas. SETTING:Academic research unit. PATIENT(S):Among 59 women with symptomatic myomas who underwent myomectomy, 42 were treated preoperatively ...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2015.04.025
更新日期:2015-08-01 00:00:00
abstract::A retrospective study of 254 infertile men with serum sperm agglutination titers ranging from 4 to 1024 determined by the Kibrick agglutination test between 1954 and 1968 and reexamined in the 1970s is presented. 36 of the subjects had become fertile in the years following the testing, 30 of whom were normospermic. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)40388-2
更新日期:1974-05-01 00:00:00
abstract::The present study was undertaken to investigate not only the effectiveness of bromoergocryptine therapy in 13 women with amenorrhea-galactorrhea and hyperprolactinemia without evidence of organic pathology, but also to assess the value of pretreatment evaluation in predicting the response to therapy. Sella turcica tom...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)42490-8
更新日期:1977-04-01 00:00:00
abstract:OBJECTIVE:To investigate alterations in the overall gene expression profile of endometriosis-derived stroma with increasing concentrations of hCG by using the Affymetrix GeneChip U133 Set. DESIGN:In vitro study. SETTING:Academic research institution. PATIENT(S):Women undergoing diagnostic laparoscopic surgery for en...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.02.006
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:To investigate whether proteins secreted in urine differ between women with and without endometriosis. DESIGN:Laboratory study using human urine. SETTING:University-based laboratory. PATIENT(S):Women with and without endometriosis undergoing laparoscopy, hysteroscopy and curettage. INTERVENTION(S):Urine c...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.05.016
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To provide a step-by-step description of our published technique of single-site robot-assisted laparoscopic myomectomy with the goal of promoting its safe adoption. DESIGN:Surgical video tutorial. SETTING:University medical center. PATIENT(S):Ten women undergoing single-site robot-assisted laparoscopic myo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.07.1159
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and side effects of vaginal misoprostol with dinoprostone for cervical priming before operative hysteroscopy and to assess the cervicouterine complications related to cervical dilatation and hysteroscopic surgery. DESIGN:A prospective randomized study. SETTING:Tertiary university hos...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2006.03.039
更新日期:2006-10-01 00:00:00
abstract::The serial measurement of serum hCG concentrations is an important clinical tool used to differentiate normal from abnormal pregnancies. At hCG values below which ultrasonography can be diagnostic, the comparison of a patient's hCG dynamics to those of established expected curves of rise or fall can aid the clinician ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2012.09.014
更新日期:2012-11-01 00:00:00
abstract::In this study, acrosin activity and hyaluronic acid binding were compared in sperm from men with spinal cord injury versus sperm from healthy controls. The results showed statistically significantly lower acrosin activity and statistically significantly lower hyaluronic acid binding in spinal cord injured patients com...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.01.015
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To provide a quantitative assessment of patient knowledge about fertility and fertility preservation treatment options before the initial fertility preservation consultation at a university-based fertility preservation center. DESIGN:Prospective pilot survey containing 13 items assessing patient knowledge ab...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.02.016
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of hysteroscopic selective salpingography (HSS) as a method for diagnosing the tubal proximal occlusion shown by hysterosalpingography (HSG). DESIGN:Prospective study. SETTING:Outpatient Department of Obstetrics and Gynecology, Social Insurance Saitama Chuo Hospital, Urawa, Jap...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00324-6
更新日期:1999-10-01 00:00:00
abstract::After long-term estradiol deficiency, female rats displayed body mass gain accompanied by an increase in the size of adipocytes, an increase in hyperglycemia, and a decrease in insulinemia. The effects were reversed by daily estradiol treatment. Adiposity was suggested by the increased vascular endothelial growth fact...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.01.020
更新日期:2011-03-15 00:00:00
abstract:OBJECTIVE:To review osteoporosis, a disease characterized by low bone mass, microarchitectural deterioration of bone tissue leading to increased bone fragility and a consequent increase in fracture risk. The disorder has become a major health problem in the West, where increased life expectancy has placed new emphasis ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:
更新日期:1994-12-01 00:00:00
abstract::Intravaginal culture (IVC) is a new technique elaborated by the authors for the fertilization and culture of human oocytes. Its principle consists of fertilization and early development of the eggs in a closed, air-free milieu without the addition of CO2. One to five ovocytes are deposited in a tube completely filled ...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)59835-5
更新日期:1988-04-01 00:00:00
abstract:OBJECTIVE:To correlate apoptosis of cultured human granulosa-lutein cells (GL cells) with the outcome of IVF (embryo fragmentation and pregnancy rate) and to study the effect of insulin and insulin-like growth factor I (IGF-I) on apoptosis. DESIGN:In vitro assays. SETTING:University laboratory and private IVF center....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.08.014
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:The present study examines the safety, effectiveness, and local tissue response for a new transcervical fallopian tube permanent contraceptive device, the STOP device (Conceptus, Inc., San Carlos, CA). DESIGN:Nonrandomized prospective evaluation of tubal occlusion and histologic response. SETTING:Inpatient,...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)02858-8
更新日期:2001-11-01 00:00:00
abstract::In this study of 132 infertile couples, findings with hysterosalpingography (HSG) were compared with those observed at subsequent culdoscopy or laparoscopy. Both procedures correctly revealed normal tubes in 29% of the subjects and identical abnormalities in 24%. A complete agreement between the two procedures was thu...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)41531-1
更新日期:1975-12-01 00:00:00
abstract:OBJECTIVE:To determine Müllerian inhibiting substance (MIS) levels in follicular fluid (FF) and sera of IVF patients. DESIGN:Prospective study. SETTING:Fertility center. PATIENT(S):Sixty-six patients: 20 with tubal factor infertility, 17 with polycystic ovary syndrome (PCOS), and 29 with endometriosis. INTERVENTION...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81417-3
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the risk that nulliparity poses to the outcome of twin pregnancies, an issue that gained importance due to the rise of twin gestations following assisted reproduction interventions. DESIGN:A prospective cohort study. SETTING AND PATIENT(S):Between January 1, 2004, and January 7, 2008, we prospec...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.12.035
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:To present and determine the impact of the Mindfulness-Based Program for Infertility (MBPI). DESIGN:Controlled clinical trial. SETTING:University research unit. PATIENT(S):Fifty-five infertile women completed the MBPI, and 37 infertile women were assigned to a control group. INTERVENTION(S):The MBPI inclu...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.05.036
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between fetal and maternal catechol-O-methyltransferase (COMT) Val158Met and methyl tetrahydrofolate reductase (MTHFR) C677T functional polymorphisms and preeclampsia, examining its influence on placental COMT and in maternal 2-methoxyestradiol (2-ME) plasma levels. DESIGN:Prospec...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.09.019
更新日期:2016-01-01 00:00:00
abstract::The effect of six metabolically active compounds, namely caffeine, kallikrein, cyclic adenosine 3':5'-monophosphate, prostaglandin E, triiodothyronine, and insulin on spermatozoal motility was investigated. Hypokinetic and normokinetic semen specimens from fertile and infertile patients were incubated with various con...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract:OBJECTIVE:To compare conventional two- (2-D) and three-dimensional (3-D) scanning of the uterine cavity with and without saline contrast medium. DESIGN:Observational pilot study. SETTING:University-based fertility service. PATIENT(S):Ten IVF patients requiring uterine cavity assessment. INTERVENTION(S):Two-dimensio...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)58651-8
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To investigate whether treatment with progestogens in the first trimester of pregnancy would decrease the incidence of miscarriage in women with a history of unexplained recurrent miscarriage. DESIGN:Systematic review and meta-analysis. SETTING:Not applicable. PATIENT(S):Women with a history of unexplained...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.fertnstert.2016.10.031
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:To study differences between robotic and laparoscopic approach in Essure device removal. DESIGN:Demonstration video of two different surgical approaches. SETTING:Clinico San Carlos University Hospital in Madrid, Spain. PATIENT(S):A total of 737 Essure devices were implanted until June 2017 in Clinico San C...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.03.025
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:Potential reparation of sperm DNA fragmentation in the oocyte may disturb any relationship between DNA-damaged sperm and the implantation ability of resulting embryos. To rule out this factor, we analyzed the consequences of sperm DNA fragmentation on IVF-ET outcome in women with healthy ovarian function. DE...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2007.02.022
更新日期:2008-01-01 00:00:00