Abstract：
:We have previously demonstrated circulating and tissue-fixed immune complexes containing the small cytoplasmic ribonucleoprotein antigen Ro and immunoglobulin G (IgG) in a case of sicca syndrome associated with primary biliary cirrhosis. To establish the overall prevalence of such complexes in liver disease, we performed dissociation experiments under conditions of Ro antigen excess. Of the diseases tested, Ro-containing immune complexes were restricted to cases with primary biliary cirrhosis. Sera from 29 of the 47 patients with primary biliary cirrhosis (60%) showed IgG-containing immune complexes; 10 of the 29 sera samples (34%) positive for IgG-containing immune complexes exhibited immune complexes composed of Ro and anti-Ro IgG. These complexes sedimented predominantly as intermediate or large aggregates and were encountered most frequently in cases with extra-hepatic features.
journal_name
Gastroenterologyjournal_title
Gastroenterologyauthors
Penner Edoi
10.1016/0016-5085(86)91129-7subject
Has Abstractpub_date
1986-03-01 00:00:00pages
724-7issue
3eissn
0016-5085issn
1528-0012pii
0016-5085(86)91129-7journal_volume
90pub_type
杂志文章相关文献
GASTROENTEROLOGY文献大全abstract：:Two infants under 3 mo of age who presented with obstructive jaundice secondary to cholelithiasis are reported. Neither infant had any congenital anatomic abnormality of the biliary tract leading to stasis, yet both had cultures of gallbladder bile that grew abundant bacteria. In both, recovery of gallbladder bile and...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1016/s0016-5085(89)91579-5
更新日期：1989-02-01 00:00:00
abstract：:A patient who developed obstructive jaundice as a complication of a liver biopsy is presented. The jaundice was found to be attributable to obstruction of the biliary tree at the level of the bifurcation by an intrahepatic hematoma. The patient had a complete and spontaneous recovery. ...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:Twenty patients with antimicrobiol-associated diarrhea had a symptomatic relapse after oral vancomycin therapy. All patients had stool examinations which implicated C. difficile as the causative agent, and 16 had pseudomembranous colitis. Clinical courses were characterized by resolution of symptoms with recurrence of...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1980-03-01 00:00:00
abstract：BACKGROUND & AIMS:Photodynamic therapy (PDT) for high-grade dysplasia (HGD) in Barrett's esophagus is a Food and Drug Administration-approved alternative to esophagectomy. Critical information regarding overall survival of patients followed up long-term after these therapies is lacking. Our aim was to compare the long-...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2007.02.017
更新日期：2007-04-01 00:00:00
abstract：:We have examined the receptor binding of radio-iodinated murine epidermal growth factor and the effects of epidermal growth factor on both amylase release and incorporation of [3H]leucine into protein in isolated adult mouse pancreatic acini in primary culture. Binding of radioiodinated murine epidermal growth factor ...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1983-08-01 00:00:00
abstract：:Heterogeneity of colonic mucin glycoprotein was examined in rectal mucosal biopsy specimens from a variety of primate species (Saguinus oedipus, n = 18; Macaca mulatta, n = 2; Macaca fascicularis, n = 2; Aotus trivirgatus, n = 2; Saimiri sciureus, n = 2; and Callithrix jacchus, n = 2). After initial separation of radi...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1016/s0016-5085(85)80127-x
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND & AIMS:Nuclear factor of activated T cells transcription factors plays a central role in immunity by regulating the expression of multiple cytokines and other regulatory molecules, many of which have been heavily implicated in the pathogenesis of inflammatory bowel disease. However, few studies have directly...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2004.01.013
更新日期：2004-04-01 00:00:00
abstract：:The effects of a variety of substances influencing the initiation of cyclic motor events at the gastroduodenal junction were studied in conscious sheep. A significant and long-lasting decrease in the frequency of cyclic events from approximately 100 min to 30-40 min was elicited by the intraduodenal bulb administratio...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：:We have recently demonstrated that ritanserin, a serotonin 5-hydroxytryptamine receptor antagonist void of systemic effects, caused a significant reduction of portal pressure in conscious cirrhotic dogs. The mechanism by which ritanserin lowers portal pressure is poorly defined. We investigated the splanchnic and syst...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1016/0016-5085(90)91302-m
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND & AIMS:The secretion and function of antral histamine are not known. The aims of this study were to characterize the mechanisms of histamine release from the gastric antrum of humans, dogs, and rats and to determine whether histamine can influence the secretion of somatostatin and gastrin. METHODS:Somatosta...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1016/0016-5085(95)90645-2
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND & AIMS:Nonalcoholic fatty liver disease (NAFLD) is associated with increased risk of hepatic, cardiovascular, and metabolic diseases. High-protein diets, rich in methionine and branched chain amino acids (BCAAs), apparently reduce liver fat, but can induce insulin resistance. We investigated the effects of d...
journal_title：Gastroenterology
pub_type： 杂志文章,随机对照试验
doi：10.1053/j.gastro.2016.10.007
更新日期：2017-02-01 00:00:00
abstract：:Gastrinomas were localized by concurrent blood sampling in the hepatic vein and portal vein tributaries in 10 of 12 Zollinger-Ellison patients. In one patient, the portal vein could not be catheterized; in the other, a gastrin gradient could not be picked up in either of two examinations. Six of the patients were subs...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1979-09-01 00:00:00
abstract：:The goal of this study was to identify the structural and compositional features of human gallstones that influence in vitro gallstone dissolution in the cholesterol solvent monooctanoin. Gallstones were obtained from 86 consecutive patients who had at least three morphologically similar stones. One stone from each pa...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1016/0016-5085(87)90320-9
更新日期：1987-07-01 00:00:00
abstract：:The effect of magnesium on calcium- and pentagastrin-induced gastric acid secretion and on calcium-induced gastrin secretion were studied in healthy volunteers. Intravenous infusion of calcium gluconate increased serum gastrin concentration as well as gastric volume secretion, acidity, and acid output. Addition of mag...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1975-05-01 00:00:00
abstract：BACKGROUND & AIMS:After liver injury, bone marrow-derived liver sinusoidal endothelial cell progenitor cells (BM SPCs) repopulate the sinusoid as liver sinusoidal endothelial cells (LSECs). After partial hepatectomy, BM SPCs provide hepatocyte growth factor, promote hepatocyte proliferation, and are necessary for norma...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2012.08.008
更新日期：2012-12-01 00:00:00
abstract：:The effect of secretin5-27 and four substituted analogues (9 Gln-secretin5-27, 15-Asn-secretin5-27, 9-Gln-15-Asn-secretin5-27, and 15-Lys-secretin5-27) on pancreatic secretion in the rat and guinea pig was examined. Secretin5-27 retained significant pancreatic secretory activity in both species. Its efficacy (intrinsi...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1978-08-01 00:00:00
abstract：:A 45-minute infusion of an octapeptide of cholecystokinin (Kinevac; Squibb Diagnostics, New Brunswick, NJ) was used to measure the gallbladder ejection fraction during cholescintigraphy in 40 normal volunteers. Cholecystokinin cholescintigraphy was shown to be a reproducible test. The maximum mean gallbladder ejection...
journal_title：Gastroenterology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0016-5085(91)90540-2
更新日期：1991-09-01 00:00:00
abstract：BACKGROUND & AIMS:Some acute enteric infections are associated with the development of functional gastrointestinal disorders, most commonly irritable bowel syndrome but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection has increased in incidence and severity, however, few stud...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2015.07.059
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND/AIMS:Carbonic anhydrase activity plays a role in electrolyte transport in many tissues. This study examined the effect of the carbonic anhydrase inhibitor acetazolamide on human basal and prostaglandin E2- and acid-stimulated duodenal mucosal bicarbonate secretion and transmucosal electrical potential differ...
journal_title：Gastroenterology
pub_type： 临床试验,杂志文章
doi：10.1016/0016-5085(95)90013-6
更新日期：1995-01-01 00:00:00
abstract：:Development of an intraabdominal bile collection (biloma) usually occurs secondary to traumatic or iatrogenic injury including abdominal surgery, percutaneous catheter drainage, and transhepatic cholangiogram. We present a case of hepatic subcapsular biloma following endoscopic retrograde cholangiography and identifie...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1988-05-01 00:00:00
abstract：BACKGROUND & AIMS:Although it has been shown that des-acyl ghrelin decreases food intake and gastric emptying, no previous studies have examined the effects of des-acyl ghrelin on physiologic fed and fasted motor activity in the gastrointestinal tract. METHODS:We examined the effects of intraperitoneal (IP) administra...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2005.04.015
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND & AIMS:Although different brands of fecal immunochemical tests (FITs) are used for colorectal cancer (CRC) screening, few studies have compared their accuracy in detecting advanced neoplasia. METHODS:We performed a large prospective cohort study within the Dutch national CRC screening program to evaluate 2 ...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2018.07.021
更新日期：2018-11-01 00:00:00
abstract：:To study directly the functions of the cells that line the bile ducts inside the liver, we developed a new technique for isolating intrahepatic bile duct epithelial cells (IBDECs) from normal rat liver. Parenchymal and nonparenchymal cells were separated from whole liver by enzymatic digestion and mechanical disruptio...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1016/0016-5085(89)91695-8
更新日期：1989-11-01 00:00:00
abstract：:We are reporting a patient with acute leptospirosis whose creatinine phosphokinase was markedly elevated secondary to an associated myositis. In patients presenting with acute hepatitis, an elevated creatinine phosphokinase should suggest the diagnosis of leptospirosis. Our patient's course of illness was made unusual...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：BACKGROUND & AIMS:The cyclic adenosine monophosphate (cAMP) and Ca(2+) signaling pathways synergize to regulate many physiological functions. However, little is known about the mechanisms by which these pathways interact. We investigated the synergy between these signaling pathways in mouse pancreatic and salivary glan...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2013.03.047
更新日期：2013-07-01 00:00:00
abstract：:We constructed ileocolonic loops of distal ileum, ileocolonic sphincter, and proximal colon in 5 dogs; neuromuscular continuity was maintained between loop and intact bowel by a bridge of tunica muscularis. To study ileocolonic sphincter function, we recorded myoelectric activity from subserosal electrodes and intralu...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：BACKGROUND & AIMS:Alcoholic hepatitis (AH) is characterized by hepatocellular damage, inflammation, and fibrosis. We performed a prospective study to associate hepatic expression of the CXC subfamily of chemokines with histology findings and prognosis of patients with AH. METHODS:Liver biopsy samples from 105 patients...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2009.01.056
更新日期：2009-05-01 00:00:00
abstract：BACKGROUND & AIMS:Toll-like receptor (TLR)-dependent signaling was proposed as immunotherapeutic targets against invading pathogens and tumorigenesis. Here, we investigated whether TLR5-dependent signaling modulates colonic tumor development in mouse xenograft model of human colon cancer. METHODS:The expression of mye...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2008.04.022
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND & AIMS:The finding of bone morphogenetic protein (BMP) receptor 1a mutations in juvenile polyposis suggests that BMPs are important in colorectal cancer (CRC). We investigated the BMP pathway in sporadic CRC. METHODS:We investigated BMP receptor (BMPR) expression using immunoblotting and sequenced BMPR2 in ...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1053/j.gastro.2008.02.059
更新日期：2008-05-01 00:00:00
abstract：BACKGROUND & AIMS:Amidated gastrins are acid secretagogues and growth factors. Their precursor, progastrin, is a growth factor but not a secretagogue. Cleavage of progastrin at Arg94/95 determines the expression of these two alternative patterns of biological activity. We examined the hypothesis that cleavage at Arg94/...
journal_title：Gastroenterology
pub_type： 杂志文章
doi：10.1016/s0016-5085(98)70086-1
更新日期：1998-11-01 00:00:00
