Abstract：
:Twenty patients with antimicrobiol-associated diarrhea had a symptomatic relapse after oral vancomycin therapy. All patients had stool examinations which implicated C. difficile as the causative agent, and 16 had pseudomembranous colitis. Clinical courses were characterized by resolution of symptoms with recurrence of diarrhea at 4--21 days after vancomycin was discontinued. Studies of stools collected sequentially showed that vancomycin failed to eliminate C. difficile despite susceptibility to this agent with in vitro testing. A review of our records shows the incidence os symptomatic relapse is approximately 14%. This experience emphasizes the importance of adequate follow-up in patients treated with oral vancomycin for antibiotic-associated diarrhea or colitis due to C. difficile.
journal_name
Gastroenterologyjournal_title
Gastroenterologyauthors
Bartlett JG,Tedesco FJ,Shull S,Lowe B,Chang Tsubject
Has Abstractpub_date
1980-03-01 00:00:00pages
431-4issue
3eissn
0016-5085issn
1528-0012pii
S0016508580000376journal_volume
78pub_type
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