On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia.

Abstract:

:Diapausing pupae of Cecropia respond to a bacterial infection by the selective synthesis of RNA and 15-20 hemolymph proteins. Of these we have purified lysozyme and two classes of antibacterial proteins called cecropins and attacins. The primary structure has been determined for the lysozyme, one attacin and five cecropins. We have also prepared a cDNA bank, isolated and sequenced clones corresponding to the lysozyme, the two main attacins and one cecropin. The results of these structural studies are briefly summarized. Finally we review the solid phase synthesis of cecropin A and B and 9 analogs of cecropin A.

journal_name

Dev Comp Immunol

authors

Boman HG,Faye I,von Hofsten P,Kockum K,Lee JY,Xanthopoulos KG,Bennich H,Engström A,Merrifield RB,Andreu D

doi

10.1016/0145-305x(85)90018-7

subject

Has Abstract

pub_date

1985-07-01 00:00:00

pages

551-8

issue

3

eissn

0145-305X

issn

1879-0089

pii

0145-305X(85)90018-7

journal_volume

9

pub_type

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