Different HLA associated gene combinations contribute to susceptibility for coeliac disease and dermatitis herpetiformis.

abstract：:A method not needing fluoroscopic control for positioning a manometric probe in the gastroduodenal tract is described. It is based on hydrostatic pressure variations occurring at each recording port of a multichannel perfused probe after changes in patient's position. The data are fed into a computer and the schematic...

journal_title：Gut

authors： Bortolotti M,Bersani G

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:A rapid, reliable, and accurate test for the diagnosis of infection with Helicobacter pylori is needed for screening dyspeptic patients before referral for endoscopy. AIM:To compare a new rapid whole blood test (Helisal rapid blood, Cortecs), two serum enzyme linked immunosorbent assays (ELISAs; Helico-G, S...

journal_title：Gut

authors： Reilly TG,Poxon V,Sanders DS,Elliott TS,Walt RP

更新日期：1997-04-01 00:00:00

abstract：:Early carcinoma of the gastric remnant was diagnosed in 19 patients between January 1976 and January 1986. In all patients early cancer was suspected at endoscopy and confirmed by biopsy and histology. The main reason for endoscopic examination was diffuse epigastric pain suggestive of stump gastritis. The surgical pr...

journal_title：Gut

authors： Pointner R,Schwab G,Königsrainer A,Bodner E,Schmid KW

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Although peroxisome proliferator activated receptor gamma (PPARgamma) agonists have been implicated in differentiation and growth inhibition of cancer cells, the potential therapeutic and chemopreventive effects on gastric cancer are poorly defined. We examined the in vitro and in vivo effects of PP...

journal_title：Gut

authors： Leung WK,Bai AH,Chan VY,Yu J,Chan MW,To KF,Wu JR,Chan KK,Fu YG,Chan FK,Sung JJ

更新日期：2004-03-01 00:00:00

abstract：:Nineteen healthy subjects were studied and 17 patients with gastric ulcer before and after ulcer healing with carbenoxolone. Gastric deoxytibonucleic acid (DNA) loss was measured as an index of epithelial cell turnover, and N-acetylneuraminic acid (NANA) content of gastric juice as an index of mucus secretion. In norm...

journal_title：Gut

authors： Domschke W,Domschke S,Hagel J,Demling L,Croft DN

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Extrahepatic manifestations of HCV are responsible for morbidity and mortality in many chronically infected patients. New, interferon-free antiviral treatment regimens, which present the opportunity to treat all HCV-infected patients, call for a better understanding of the benefits of treating non-c...

journal_title：Gut

authors： Cacoub P,Desbois AC,Comarmond C,Saadoun D

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Treatment cessation in chronic HBV infection may be durable in certain patient subgroups before hepatitis B surface antigen (HBsAg) seroclearance. The role of serum HBV RNA in determining treatment cessation suitability has not been well-investigated. METHODS:Nucleos(t)ide analogue (NUC) treatment was disco...

journal_title：Gut

authors： Seto WK,Liu KS,Mak LY,Cloherty G,Wong DK,Gersch J,Lam YF,Cheung KS,Chow N,Ko KL,To WP,Fung J,Yuen MF

更新日期：2020-08-05 00:00:00

abstract：BACKGROUND:Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which the colonic mucosa is infiltrated with plasma cells producing IgG autoantibodies. It is not known whether this represents a local mucosal response which has switched to IgG or a peripheral response which may have been initiated by perip...

journal_title：Gut

authors： Thoree VC,Golby SJ,Boursier L,Hackett M,Dunn-Walters DK,Sanderson JD,Spencer J

更新日期：2002-07-01 00:00:00

abstract：:Glycosylation is a key modification of proteins and lipids and is involved in most intermolecular and intercellular interactions. The gastrointestinal mucus gel is continuous and can be divided into two layers: a secreted loosely associated layer and a layer firmly attached to the mucosa. In addition, the membrane-bou...

journal_title：Gut

authors： Moran AP,Gupta A,Joshi L

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Faecal concentrations of the protein calprotectin have been found to be elevated in patients with colorectal neoplasia, suggesting that it might be used as a screening tool for colorectal cancer as well as adenomas. AIMS:To measure the sensitivity and specificity of faecal calprotectin for the detection of ...

journal_title：Gut

authors： Kronborg O,Ugstad M,Fuglerud P,Johne B,Hardcastle J,Scholefield JH,Vellacott K,Moshakis V,Reynolds JR

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The colons of patients with pneumatosis cystoides coli produce excessive H2. Exposure to alkyl halides could explain this. Six consecutive patients who had pneumatosis cystoides coli while taking chloral hydrate (1-5+ g/day) are reported. Patients 2 and 3 were investigated after they had ceased chlo...

journal_title：Gut

authors： Florin TH

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:The long-term performance of colorectal cancer (CRC) screening programmes based on a 2-year faecal immunochemical test (FIT) is still unclear. METHODS:In a sample of 50 to 69-year-olds repeatedly screened with the FIT (OC-Hemodia latex agglutination test; cut-off: 20 µg haemoglobin/g faeces), we examined: (...

journal_title：Gut

authors： Zorzi M,Hassan C,Capodaglio G,Fedato C,Montaguti A,Turrin A,Rosano A,Monetti D,Stocco C,Baracco S,Russo F,Repici A,Rugge M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Invasion of the intestinal mucosa by leucocytes is a characteristic of intestinal inflammation but the role of the epithelium in orchestrating this recruitment has not been examined in vivo. Cultured intestinal epithelial cells secrete a wide variety of chemokines, often in response to agents present in the ...

journal_title：Gut

authors： Ohtsuka Y,Lee J,Stamm DS,Sanderson IR

更新日期：2001-10-01 00:00:00

abstract：:Polyacrylamide gel electrophoresis of pure pancreatic juice from 14 healthy normal subjects, 11 chronic alcoholics without detectable pancreatic disease, 15 patients with pancreatitis, and two with cancer of the pancreas consistently demonstrated the presence of two variants of trypsinogen with different electrophoret...

journal_title：Gut

authors： Rinderknecht H,Renner IG,Carmack C

更新日期：1979-10-01 00:00:00

abstract：OBJECTIVE:To examine the relationship between Mediterranean diet and risk of later-onset Crohn's disease (CD) or ulcerative colitis (UC). DESIGN:We conducted a prospective cohort study of 83 147 participants (age range: 45-79 years) enrolled in the Cohort of Swedish Men and Swedish Mammography Cohort. A validated food...

journal_title：Gut

authors： Khalili H,Håkansson N,Chan SS,Chen Y,Lochhead P,Ludvigsson JF,Chan AT,Hart AR,Olén O,Wolk A

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:We previously described hepatitis reactivation in two carriers of the hepatitis C virus (HCV) genotype 2c. AIM:To assess the relationship between HCV genotypes and risk of hepatitis reactivation, we studied the course of aminotransferases in patients infected with the two relevant genotypes in Italy. PATIE...

journal_title：Gut

authors： Rumi MG,De Filippi F,La Vecchia C,Donato MF,Gallus S,Del Ninno E,Colombo M

更新日期：2005-03-01 00:00:00

abstract：:A family is described in which there occurred two cases of the lupoid type of active chronic hepatitis with cirrhosis, one of chronic persistent hepatitis, and one of myasthenia gravis. The two cases of lupoid hepatitis were in the proposita, a schoolgirl aged 16 years, and her great-aunt aged 69 years whom she had ne...

journal_title：Gut

authors： Whittingham S,Mackay IR,Kiss ZS

更新日期：1970-10-01 00:00:00

abstract：:To investigate factors which predispose to relapse in patients with ulcerative colitis, we conducted a survey to compare the events occurring in the four weeks preceding the clinic attendance of 62 outpatients in remission with those taking place in the same period before the onset of relapse in 21 patients attending ...

journal_title：Gut

authors： Rampton DS,McNeil NI,Sarner M

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVES:Roux-en-Y gastric bypass (RYGB) has greater efficacy for weight loss in obese patients than gastric banding (BAND) surgery. We hypothesise that this may result from different effects on food hedonics via physiological changes secondary to distinct gut anatomy manipulations. DESIGN:We used functional MRI, ea...

journal_title：Gut

authors： Scholtz S,Miras AD,Chhina N,Prechtl CG,Sleeth ML,Daud NM,Ismail NA,Durighel G,Ahmed AR,Olbers T,Vincent RP,Alaghband-Zadeh J,Ghatei MA,Waldman AD,Frost GS,Bell JD,le Roux CW,Goldstone AP

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Gastric carcinogenesis is a multifactorial, multistep process, in which chronic inflammation plays a major role. AIMS:In order to ascertain whether free radical mediated oxidative DNA damage is involved in such a process, concentrations of 8-hydroxydeoxyguanosine (8OHdG), a mutagenic/carcinogenic adduct, an...

journal_title：Gut

authors： Farinati F,Cardin R,Degan P,Rugge M,Mario FD,Bonvicini P,Naccarato R

更新日期：1998-03-01 00:00:00

abstract：:Five patients in whom small-intestinal bypass was performed for severe obesity had a second operation 11-19 months later because of insufficient weight loss. Mucosal enzyme activities and histological appearance were investigated in biopsies from different parts of the functioning and excluded small intestine. These w...

journal_title：Gut

authors： Asp NG,Gudmand-Høyer E,Andersen B,Berg NO

更新日期：1979-07-01 00:00:00

abstract：:It is well known that chronic encephalopathy may be a major complication after the establishment of a surgical portal caval shunt for an episode of variceal haemorrhage. In an effort to minimise this problem Warren and colleagues developed the distal splenorenal shunt where the portal and mesenteric blood flow to the ...

journal_title：Gut

authors： Bleasel AF,Waugh RC,McCaughan GW

更新日期：1989-10-01 00:00:00

abstract：:Intestinal adaptation (small intestinal weight and length, weight of the caecum and of the residual colon) to feeding different doses (0-5-50-500 mg/kg bw) of the absorbable, competitive alpha-glucosidase inhibitors BAY m 1099 and BAY o 1248 for three, seven, or 28 days was studied in rats. With the highest dose of ei...

journal_title：Gut

authors： Lembcke B,Löser C,Fölsch UR,Wöhler J,Creutzfeldt W

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Saccharomyces boulardii is a non-pathogenic yeast which exerts trophic effects on human and rat small intestinal mucosa. AIMS:To examine the effects of S boulardii on ileal adaptation after proximal enterectomy in rats. METHODS:Wistar rats, aged eight weeks, underwent 60% proximal resection or transection ...

journal_title：Gut

authors： Buts JP,De Keyser N,Marandi S,Hermans D,Sokal EM,Chae YH,Lambotte L,Chanteux H,Tulkens PM

更新日期：1999-07-01 00:00:00

abstract：:Thirty-two patients with diarrhoea, on average four years following truncal vagotomy and drainage, were studied. A comparison was made with 24 patients without postvagotomy diarrhoea. The incidence of bacterial colonization of the upper small intestine was no different in the two groups, though patients with a gastroe...

journal_title：Gut

authors： Browning GG,Buchan KA,Mackay C

更新日期：1974-08-01 00:00:00

abstract：:Our life expectancy is increasing, leading to a rise in the ageing population. Ageing is associated with a decline in physiological function and adaptive capacity. Altered GI physiology can affect the amount and types of nutrients digested and absorbed as well as impact the intestinal microbiota. The intestinal microb...

journal_title：Gut

authors： An R,Wilms E,Masclee AAM,Smidt H,Zoetendal EG,Jonkers D

更新日期：2018-12-01 00:00:00

abstract：:Strains of E. coli from the faeces of patients with active ulcerative colitis and with colitis in remission were examined for haemolysin and necrotoxin production. Cultures from 63 patients with active colitis grew haemolytic E. coli in 23 (37%) as compared with 24 (21%) from 115 patients whose disease was in remissio...

journal_title：Gut

authors： Cooke EM,Ewins SP,Hywel-Jones J,Lennard-Jones JE

更新日期：1974-02-01 00:00:00

abstract：:Serumfolate folate levels and the bacteriology of the small intestine were studied in 13 patients with jejunal diverticulosis, 29 patients with partial gastrectomy, and five patients with ileal disease. The mean serum folate level in the patients with partial gastrectomy (7.2 mmug/ml) was similar to that of control su...

journal_title：Gut

authors： Hoffbrand AV,Tabaqchali S,Booth CC,Mollin DL

更新日期：1971-01-01 00:00:00

abstract：:The cause of a biliary tract stricture may be difficult to determine radiologically. Exfoliative biliary cytology was evaluated in 62 patients (median age 65 years, range 30-94) with biliary tract strictures presenting to the Hepatobiliary Unit between January 1984 and December 1989. Bile samples were taken during end...

journal_title：Gut

authors： Davidson B,Varsamidakis N,Dooley J,Deery A,Dick R,Kurzawinski T,Hobbs K

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:An increasing number of case reports indicate potential nephrotoxicity of 5-aminosalicylic acid (5-ASA), which shares similarities with the chemical structures of both phenacetin and acetylsalicylic acid. AIM:In a point prevalence study the occurrence of sensitive indices indicative of early kidney malfunct...

journal_title：Gut

authors： Schreiber S,Hämling J,Zehnter E,Howaldt S,Daerr W,Raedler A,Kruis W

更新日期：1997-06-01 00:00:00