Visfatin protein may be responsible for suppression of proliferation and apoptosis in the infantile mice ovary.

abstract：BACKGROUND AND AIM:Interleukin-22 (IL-22), plays a vital role in the mucosal repair of inflammatory bowel disease (IBD). Serum levels of IL-22 and IL-22 binding protein (IL-22BP), a soluble inhibitory IL-22 receptor, were measured in patients with IBD to investigate the profile of IL-22 in the systemic circulation. ME...

journal_title：Cytokine

authors： Sakemi R,Mitsuyama K,Morita M,Yoshioka S,Kuwaki K,Tokuyasu H,Fukunaga S,Mori A,Araki T,Yoshimura T,Yamasaki H,Tsuruta K,Morita T,Yamasaki S,Mizoguchi A,Sou S,Torimura T

更新日期：2020-12-01 00:00:00

abstract：:Interleukin-6 (IL-6) is a cytokine involved in different physiologic and pathophysiologic processes including essential hypertension (EH). Associations of the IL-6 promoter region polymorphisms with circulating level of IL-6 have been reported in various studies. We detected the IL-6-597G/A polymorphism in 246 EH pati...

journal_title：Cytokine

authors： Gao SP,Pan M,Chen C,Ge LJ,Jiang MH,Luan H,Zheng JG,Deng XT,Pan HY,Zhu JH

更新日期：2011-07-01 00:00:00

abstract：:The purpose of this study is to evaluate local levels of interleukin-1 beta (IL-1 beta), -4 (IL-4), -6 (IL-6), and tumour necrosis factor-alpha (TNF-alpha), in a model of murine osteomyelitis due to Staphylococcus aureus. Cytokine levels in supernatants derived from bone homogenates were determined by enzyme-linked im...

journal_title：Cytokine

authors： Yoshii T,Magara S,Miyai D,Nishimura H,Kuroki E,Furudoi S,Komori T,Ohbayashi C

更新日期：2002-07-21 00:00:00

abstract：:Overweight and obesity are associated with chronic and subclinical inflammation due to an imbalance of inflammatory mediators. However, the association with gene polymorphism has been rarely studied in children. The aim of this study was to determine if serum concentrations of C-reactive protein (CRP) and interleukin-...

journal_title：Cytokine

authors： Todendi PF,Possuelo LG,Klinger EI,Reuter CP,Burgos MS,Moura DJ,Fiegenbaum M,Valim AR

更新日期：2016-12-01 00:00:00

abstract：:The pathogenesis of rheumatoid arthritis (RA) and psoriatic arthritis (PsA) involves an abnormal chemokine regulation. The chemokine receptor CCR4 is necessary for T cell migration to the skin. We, therefore, studied if CCR4 and its ligand macrophage-derived chemokine (MDC/CCL22) could participate in spreading the dis...

journal_title：Cytokine

authors： Flytlie HA,Hvid M,Lindgreen E,Kofod-Olsen E,Petersen EL,Jørgensen A,Deleuran M,Vestergaard C,Deleuran B

更新日期：2010-01-01 00:00:00

abstract：:The N-terminal amino acid sequence of the anti-neoplastic urinary protein (ANUP), a unique cytokine present in human granulocytes, was determined to be: Pyroglu-Leu-Lys-X-Tyr-Thr-X-Lys-Glu-Pro-Met-Thr-Ser(Thr)-Ala-Ala... This sequence showed no significant homology with any other protein when used in database searches...

journal_title：Cytokine

authors： Ridge RJ,Sloane NH

更新日期：1996-01-01 00:00:00

abstract：:Published data on the association between microRNA-146a (miR-146a) G/C polymorphism and cancer susceptibility are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. A total of 23 studies including 10,585 cases and 12,183 controls were used in the meta-analysis. Overal...

journal_title：Cytokine

authors： Qiu LX,He J,Wang MY,Zhang RX,Shi TY,Zhu ML,Mao C,Sun S,Lv FF,Zheng CL,Zhu XD

更新日期：2011-12-01 00:00:00

abstract：:Although physical therapy has been shown to be an effective method for treatment of rheumatoid arthritis, a thorough investigation on the impact of mechanical signals upon the complex cytokine network associated with pathogenesis has not yet been conducted. In the current study, our research group investigated the eff...

journal_title：Cytokine

authors： Bader RA,Wagoner KL

更新日期：2010-07-01 00:00:00

abstract：:Radiation exposure results in an inflammatory reaction with acute as well as subacute consequences. Leukocyte infiltration is one of the predominant early histological changes and involves both cytokines and adhesion molecules. Endothelial cells play a key role in this reaction. We have previously shown the increased ...

journal_title：Cytokine

authors： Van Der Meeren A,Squiban C,Gourmelon P,Lafont H,Gaugler MH

更新日期：1999-11-01 00:00:00

abstract：:Thymic interleukin-6 (IL-6), which is produced primarily by thymic epithelial cells, is an important cytokine for T cell growth and differentiation in the thymus. In the present study, we investigated the effects of autocrine IL-6 on the cytokines in primary cultures of human thymic epithelial cells. Using an antibody...

journal_title：Cytokine

authors： Tseng YL,Wu MH,Yang HC,Wang CY,Lin CF

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:Mycoplasma pneumoniae (M. pneumoniae) is a common causative agent of pneumonia in children. The aim of this study is to determine whether there is any difference in selected cytokine or chemokines response in asthmatic children compared to non-asthmatic children during acute M. pneumoniae pneumonia. METHODS:Se...

journal_title：Cytokine

authors： Chung HL,Shin JY,Ju M,Kim WT,Kim SG

更新日期：2011-05-01 00:00:00

abstract：:The induction of cytokine expression in monocytes/macrophages by bacterial endotoxin or lipopolysaccharide is a critical, highly regulated host defence response. The augmentation of LPS responses by interferon gamma (IFN-gamma), referred to as priming, is well established. However, the mechanism(s) by which priming oc...

journal_title：Cytokine

authors： Hayes MP,Freeman SL,Donnelly RP

更新日期：1995-07-01 00:00:00

abstract：:Studies have shown that following bacterial infection or endotoxin administration, immune functions are regulated differently in mice of different genetic background. Since the susceptibility to sepsis following trauma-hemorrhage is dependant on the severity of injury, it is important to determine whether genetic back...

journal_title：Cytokine

authors： Matsutani T,Anantha Samy TS,Kang SC,Bland KI,Chaudry IH

更新日期：2005-05-21 00:00:00

abstract：OBJECTIVE:Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease mediated by an autoimmune reaction to hepatocytes, the present study aimed to assess the possible associations between interleukin-4 (IL-4) variable number of tandem repeats (VNTRs) and IL-4-590 promoter polymorphisms and susceptibility to aut...

journal_title：Cytokine

authors： Mansour AI,Behairy OG,Abd Almonaem ER,Abd-Rabuh RM,Ahmed IAE

更新日期：2018-10-01 00:00:00

abstract：:This study was aimed to assess whether ex vivo treatment with granulocyte-colony stimulating factor (G-CSF) modifies biological properties of bone marrow stromal cells (BMSC) and enhances functional recovery by BMSC transplantation into infarct brain. Immunohistochemistry was conducted to characterize the cultured BMS...

journal_title：Cytokine

authors： Hokari M,Kuroda S,Chiba Y,Maruichi K,Iwasaki Y

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Adiponectin is an anti-atherogenic insulin-sensitizer hormone whose plasma concentration is lower in patients with metabolic syndrome (MS). Visceral adiposity, including epicardial adipose tissue (EAT), is closely related to the development of MS and coronary artery disease (CAD). We sought to study whether ...

journal_title：Cytokine

authors： Teijeira-Fernandez E,Eiras S,Shamagian LG,Somoza AS,Delgado C,Gonzalez-Juanatey JR

更新日期：2011-05-01 00:00:00

abstract：:It is well known that interleukin (IL)-1 is a potent activator of the hypothalamo-pituitary-adrenal axis in the rat. Many studies have reported that prostaglandins (PGs), especially PGE2, in the brain may mediate the IL-1 stimulation of corticotropin-releasing hormone release, which then leads to adrenocorticotropin (...

journal_title：Cytokine

authors： Watanobe H,Sasaki S,Takebe K

更新日期：1995-10-01 00:00:00

abstract：UNLABELLED:Hyperoxia exposure can inhibit alveolar growth in the neonatal lung through induction of p21/p53 pathways and is a risk factor for the development of bronchopulmonary dysplasia (BPD) in preterm infants. We previously found that activation of nuclear factor erythroid 2 p45-related factor (Nrf2) improved survi...

journal_title：Cytokine

authors： McGrath-Morrow SA,Lauer T,Collaco JM,Lopez A,Malhotra D,Alekseyev YO,Neptune E,Wise R,Biswal S

更新日期：2014-01-01 00:00:00

abstract：:IL-4 promotes simultaneous expression of both the CD23 and CD25 antigens in resting human B lymphocytes in a dose-dependent manner. Simultaneous three-colour flow cytometric analysis revealed that CD19+/CD23+/CD25+ triple-positive cells were derived from a CD19+/CD23-/CD25- pool, and that induction of CD23 required lo...

journal_title：Cytokine

authors： McKay CE,Cushley W

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The balance of several cytokines likely influences the resolution of glomerulonephritis. Monocyte chemoattractant protein-1(MCP-1) is a chemokine that promotes renal inflammation whereas epidermal growth factor (EGF) stimulates protective responses. Previously, high urine MCP-1(MCP-1) and low urine EGF (EGF)...

journal_title：Cytokine

authors： Chanrat E,Worawichawong S,Radinahamed P,Sathirapongsasuti N,Nongnuch A,Assanatham M,Udomsubpayakul U,Kitiyakara C

更新日期：2018-04-01 00:00:00

abstract：:Estrogens have been shown to markedly modulate the immune system. One mechanism by which estrogens could modulate the immune system is by regulating cytokines, an aspect not well-studied thus far. To address this issue, normal C57BL/6 orchiectomized mice were given estrogen and its effects on selected cytokines, inter...

journal_title：Cytokine

authors： Karpuzoglu-Sahin E,Zhi-Jun Y,Lengi A,Sriranganathan N,Ansar Ahmed S

更新日期：2001-05-21 00:00:00

abstract：:The clinical phenotype in sepsis that is observed as LPS tolerance is determined by silencing of pro-inflammatory genes like IL-1 beta (IL-1β). This study shows that facultative heterochromatin (fHC) silences IL-1β expression during sepsis, where we find dephosphorylated histone H3 serine 10 and increased binding of h...

journal_title：Cytokine

authors： Yoza BK,McCall CE

更新日期：2011-02-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection and hospitalization in infants. In spite of the enormous clinical burden caused by RSV infections, there remains no efficacious RSV vaccine. CD8 T cells mediate viral clearance as well as provide protection against a secondary ...

journal_title：Cytokine

authors： Schmidt ME,Varga SM

更新日期：2020-09-01 00:00:00

abstract：:Intestinal epithelial cells can be induced to secrete the chemokine interleukin (IL)-8 during inflammation. The PAR-2 receptor is believed to play a proinflammatory role and is expressed in gut epithelial cells. The aim was to investigate PAR-2 signaling in Caco-2 intestinal epithelial cells, with respect to chemokine...

journal_title：Cytokine

authors： Fyfe M,Bergström M,Aspengren S,Peterson A

更新日期：2005-09-07 00:00:00

abstract：OBJECTIVES:Vascular endothelial cell growth factor (VEGF) plays an important role in the biology of gynecological cancer, usually linked with aggressive tumour behaviour and a poor postoperative outcome. Yet, its role in benign breast/gynecological conditions is less clear. METHODS:Serum VEGF was analysed in a series ...

journal_title：Cytokine

authors： Koukourakis MI,Limberis V,Tentes I,Kontomanolis E,Kortsaris A,Sivridis E,Giatromanolaki A

更新日期：2011-03-01 00:00:00

abstract：:Expression of cytokine genes, TNF-alpha, TNF-beta and IFN-gamma, in human astroglial cell lines and in fresh brain specimens was studied by PCR. mRNA transcripts of TNF-alpha could be detected in three out of five astrocytomas and neuroblastoma cell lines, and after stimulation with IL-1 beta/IFN-gamma or LPS/IFN-gamm...

journal_title：Cytokine

authors： Nitta T,Ebato M,Sato K,Okumura K

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Immune and inflammatory responses, mediated by cytokines, play important roles in the pathophysiology of asthma. These responses are associated with over expression of T helper (Th)-2 cytokine, particularly interleukin (IL)-4 and IL-5, and decreased expression of Th-1 cytokine, IL-2 and IFN-γ. We...

journal_title：Cytokine

authors： Lama M,Chatterjee M,Nayak CR,Chaudhuri TK

更新日期：2011-09-01 00:00:00

abstract：:Tumour necrosis factor (TNF) is a key regulator of inflammation and immunity. The cellular effects exerted by TNF depend, apart from NF-kappaB-directed gene transcription, largely on its ability to activate phospholipase A2(PLA2), yielding the release of arachidonic acid (AA) and its metabolites. AA metabolites, espec...

journal_title：Cytokine

authors： van Puijenbroek AA,Wissink S,van der Saag PT,Peppelenbosch MP

更新日期：1999-02-01 00:00:00

abstract：:Interleukin 15 (IL-15) is a cytokine with many functional characteristics that are similar to IL-2. Most of the functional activities that IL-2 and IL-15 support have been evaluated in short-term assays. It was our intention, then, to determine the long-term effects of IL-15 in comparison to IL-2. These studies were p...

journal_title：Cytokine

authors： Farner NL,Gan J,de Jong JL,Leary TP,Fenske TS,Buckley P,Dunlap S,Sondel PM

更新日期：1997-05-01 00:00:00

abstract：:The functions of phagocytic cells against pathogens are initiated by the interaction between membrane receptors and molecular structures which compose the cell wall of these microorganisms. Thus our study aimed to identify the neutrophil receptors involved in the recognition of different strains of Paracoccidioides br...

journal_title：Cytokine

authors： Balderramas HA,Penitenti M,Rodrigues DR,Bachiega TF,Fernandes RK,Ikoma MR,Dias-Melicio LA,Oliveira SL,Soares ÂM

更新日期：2014-05-01 00:00:00