Role of prostaglandins E1, E2 and F2 alpha in the brain in interleukin 1 beta-induced adrenocorticotropin secretion in the rat.

abstract：BACKGROUND:Alterations in β common (βC) and γ common (γC) chain cytokines have been described in pulmonary tuberculosis. However, their role in tuberculous lymphadenitis (TBL) disease has not been assessed. METHODS:Thus, in the present study, we have examined the systemic levels of βC and γC chain cytokines in TBL, la...

journal_title：Cytokine

authors： Kathamuthu GR,Moideen K,Sridhar R,Baskaran D,Babu S

更新日期：2021-02-01 00:00:00

abstract：:Identifying and blocking chemokine inflammatory mediators in pediatric opsoclonus-myoclonus syndrome (OMS) is critical to the treatment of this autoimmune, paraneoplastic, neurological disorder. In a prospective, case-control, clinico-scientific study of children with OMS compared to non-inflammatory neurological cont...

journal_title：Cytokine

authors： Pranzatelli MR,Tate ED,McGee NR,Ransohoff RM

更新日期：2013-10-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal disease characterized by overwhelming inflammation response and multiple organ damage. Most of the clinical and laboratory manifestations of HLH are thought to be related to hypercytokinemia and organ infiltration with lymphocytes and histiocytes. The aim...

journal_title：Cytokine

authors： Yang SL,Xu XJ,Tang YM,Song H,Xu WQ,Zhao FY,Shen DY

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Hypertension is one of the most prominent risk factors for coronary artery disease (CAD). Treatment of hypertension is therefore important for reducing cardiovascular events and the progression of atherosclerosis. Several treatment strategies are common in clinical practice for example the use of ACE-blocker...

journal_title：Cytokine

authors： Klinghammer L,Urschel K,Cicha I,Lewczuk P,Raaz-Schrauder D,Achenbach S,Garlichs CD

更新日期：2013-05-01 00:00:00

abstract：:Dermal wounding is accompanied by inflammation and the resulting proinflammatory cytokines, including interleukin (IL)-6, are thought to play an important role in the repair process. IL-6 is produced by normal human keratinocytes to various dermatological diseases and we have recently shown it is also required for nor...

journal_title：Cytokine

authors： Sugawara T,Gallucci RM,Simeonova PP,Luster MI

更新日期：2001-09-21 00:00:00

abstract：:The present study demonstrates that liposomes coated with synthesized neoglycolipids constructed from mannotriose and dipalmitoylphosphatidylethanolamine (Man3-DPPE) activate peritoneal macrophages (PEMs) to up-regulate expression of co-stimulatory molecules and preferentially secrete IL-12. Injection of Man3-DPPE-coa...

journal_title：Cytokine

authors： Takagi H,Furuya N,Kojima N

更新日期：2007-12-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) is a notable chemokine that plays critical roles in angiogenesis and vasculogenesis. The contemporary body of literature contains a substantial amount of information regarding its chemical properties as well as its fundamental role in vascular development. Studies strongly ind...

journal_title：Cytokine

authors： Crafts TD,Jensen AR,Blocher-Smith EC,Markel TA

更新日期：2015-02-01 00:00:00

abstract：:Published data on the association between microRNA-146a (miR-146a) G/C polymorphism and cancer susceptibility are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. A total of 23 studies including 10,585 cases and 12,183 controls were used in the meta-analysis. Overal...

journal_title：Cytokine

authors： Qiu LX,He J,Wang MY,Zhang RX,Shi TY,Zhu ML,Mao C,Sun S,Lv FF,Zheng CL,Zhu XD

更新日期：2011-12-01 00:00:00

abstract：:CoPoIFN-α is a recombinant non-naturally occurring porcine interferon-α (IFN-α). It was designed by scanning 17 porcine IFN-α nonallelic subtypes and assigning the most frequently occurring amino acid in each position. We used a porcine IFN-α (PoIFN-α) derived from domestic pig as a control. Both porcine IFN-α genes w...

journal_title：Cytokine

authors： Huang L,Cao RB,Wang N,Liu K,Wei JC,Isahg H,Song LJ,Zuo WY,Zhou B,Wang WW,Mao X,Chen PY

更新日期：2012-01-01 00:00:00

abstract：:Interleukin (IL-) 2 and IL-15 share the IL-2 receptor betagamma c subunits (IL-2Rbetagamma c) but have specific, unique alpha receptor subunits. We studied species specificity of human (hu), simian (si), and mouse (mu) IL-15 and found that hu and si IL-15 behaved similarly in all systems investigated. Hu and mu IL-15 ...

journal_title：Cytokine

authors： Eisenman J,Ahdieh M,Beers C,Brasel K,Kennedy MK,Le T,Bonnert TP,Paxton RJ,Park LS

更新日期：2002-11-07 00:00:00

abstract：:The development of acidic environments is a hallmark of inflammatory processes of different etiology. We have previously shown that transient exposure to acidic conditions, similar to those encountered in vivo, induces the activation of neutrophils and the phenotypic maturation of dendritic cells. We here report that ...

journal_title：Cytokine

authors： Jancic CC,Cabrini M,Gabelloni ML,Rodríguez Rodrigues C,Salamone G,Trevani AS,Geffner J

更新日期：2012-02-01 00:00:00

abstract：:The protective effect of interleukin 1 alpha (IL-1 alpha) in mice with acetaminophen (AAP)-induced hepatitis was investigated. IL-1 alpha had a significant protective effect if given 2 or more hours (up to 24 hours) before AAP; it significantly reduced mortality of mice and decreased serum transaminase level. The maxi...

journal_title：Cytokine

authors： Renić M,Culo F,Bilić A,Bukovec Z,Sabolović D,Zupanović Z

更新日期：1993-05-01 00:00:00

abstract：AIMS:This study investigates the relationships between matrix metalloproteinases, inflammations mediators and type 2 diabetes mellitus in Tunisians metabolic syndrome (Mets) patients. METHODS:The study has included 239 MetS patients and 247 controls. Mets was defined according to the NCEP-ATPIII report. Mets patients ...

journal_title：Cytokine

authors： Zayani Y,El Golli N,Zidi W,Guizani I,Boussairi S,Aloui S,Ayadi I,Ftouhi B,Feki M,Ben Romdhane N,Ben Sliman H,Allal-Elasmi M,Kaabachi N

更新日期：2016-10-01 00:00:00

abstract：:It is known that both interleukin-4 (IL-4) and IL-13 are produced by Th2-type cells and share similar biological functions with each other. However, recently accumulated evidences have revealed that IL-4 may be involved in the Th1-type response. Both thymus and activation-regulated chemokine (TARC/CCL17), a ligand for...

journal_title：Cytokine

authors： Kakinuma T,Nakamura K,Wakugawa M,Yano S,Saeki H,Torii H,Komine M,Asahina A,Tamaki K

更新日期：2002-10-07 00:00:00

abstract：:The functions of phagocytic cells against pathogens are initiated by the interaction between membrane receptors and molecular structures which compose the cell wall of these microorganisms. Thus our study aimed to identify the neutrophil receptors involved in the recognition of different strains of Paracoccidioides br...

journal_title：Cytokine

authors： Balderramas HA,Penitenti M,Rodrigues DR,Bachiega TF,Fernandes RK,Ikoma MR,Dias-Melicio LA,Oliveira SL,Soares ÂM

更新日期：2014-05-01 00:00:00

abstract：:ALT-803 is a fusion protein complex consisting of an interleukin (IL)-15 superagonist and a dimeric IL-15 receptor alpha sushi domain IgG1 Fc fusion protein. When administered to mice, ALT-803 is capable of inducing natural killer (NK) and CD8+ T cell proliferation and activation, and effectively promoting potent anti...

journal_title：Cytokine

authors： Liu B,Jones M,Kong L,Noel T,Jeng EK,Shi S,England CG,Alter S,Miller JS,Cai W,Rhode PR,Wong HC

更新日期：2018-07-01 00:00:00

abstract：:Data exist linking elevated epithelial neutrophil activating peptide (ENA-78) concentrations with myriad inflammatory conditions. ENA-78 is encoded by the CXCL5 gene which has recently been shown to be polymorphic in nature (rs352046 and rs425535). No functional data on these polymorphisms exist. We investigated wheth...

journal_title：Cytokine

authors： Zineh I,Aquilante CL,Langaee TY,Beitelshees AL,Arant CB,Wessel TR,Schofield RS

更新日期：2006-03-07 00:00:00

abstract：:Encephalitic listeriosis in sheep is a life-threatening disease. However, little is known about the cytokine response and their predictive value in this disease. The aim of present study was to assess the prognostic significance of Tumor Necrosis Factor-α (TNF-α), Interleukin-12(p40) (IL-12 p40), Interleukin-6 (IL-6),...

journal_title：Cytokine

authors： Abdlla OA,Elboshy ME,Reisha EF,Gadlla HA,El-Khodery SA

更新日期：2015-06-01 00:00:00

abstract：:The aim of the present study was to verify the expression of tumour necrosis factor (TNF)-alpha mRNA by semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) in unstimulated peripheral blood mononuclear cells (MNCs) of 15 relapsing-remitting multiple sclerosis (MS) patients who underwent treatment ...

journal_title：Cytokine

authors： Sarchielli P,Critelli A,Greco L,Sokola E,Floridi A,Gallai V

更新日期：2001-06-07 00:00:00

abstract：BACKGROUND:Fibrosis is attributed to dysregulation of tissue-remodeling. In remodeling areas, fibroblasts and macrophages actively make contact with each other. Osteopontin (OPN) is a pro-fibrotic molecule, whose expression is upregulated by interleukin (IL)-1β via secretion of its downstream cytokines, such as IL-6. H...

journal_title：Cytokine

authors： Shimodaira T,Matsuda K,Uchibori T,Sugano M,Uehara T,Honda T

更新日期：2018-10-01 00:00:00

abstract：:CC Chemokine ligand 22 (Ccl22) is a selective, high affinity ligand at the CC chemokine receptor 4 (Ccr4). We have identified cDNAs encoding both ligand and receptor of the Ccl22-Ccr4 pair in cDNA libraries of the anterior hypothalamus/pre-optic area (AH/POA) by PCR. The AH/POA is the key brain region where endogenous...

journal_title：Cytokine

authors： Osborn O,Sanchez-Alavez M,Dubins JS,Gonzalez AS,Morrison B,Hadcock JR,Bartfai T

更新日期：2011-03-01 00:00:00

abstract：:FK506 suppresses activation of T cells; however, it down-regulates E-selectin, ICAM-1 and VCAM-1 expression in inflamed tissues. In this study, we investigated the effect of FK506 on expression of those adhesion molecules on human vascular endothelial cells (HMVEC). Culture supernatant from peripheral blood mononuclea...

journal_title：Cytokine

authors： Sasakawa T,Sasakawa Y,Masunaga T,Fujitsu T,Hirayama Y,Ohkubo Y,Mutoh S

更新日期：2005-01-21 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) is the key regulator of angiogenesis in the development of various cancers. Previous studies have examined the relationship between VEGF gene promoter polymorphisms such as -2578C/A and -460C/T and bladder cancer risk; however, these results are inconclusive. Therefo...

journal_title：Cytokine

authors： Chen CH,Ho CH,Kuan-Hua Huang S,Shen CH,Wu CC,Wang YH

更新日期：2020-07-01 00:00:00

abstract：:The hypothalamic-pituitary-adrenal (HPA) axis is stimulated during immune and inflammatory processes. Interleukin 1beta (IL-1beta) and lipopolysaccharide (LPS) are known to be potent stimulators of this axis. During postnatal development, the rat seems to be hyporesponsive to many stimuli. The effects of repeated syst...

journal_title：Cytokine

authors： Bumiller A,Götz F,Rohde W,Dörner G

更新日期：1999-03-01 00:00:00

abstract：:Our aim was to explore the putative beneficial effects of low-to-moderate intensity exercise training program in patients with irritable bowel syndrome (IBS). This study evaluated the changes in blood oxidative stress status, inflammatory biomarkers and IBS severity symptoms following 24 weeks of moderate aerobic exer...

journal_title：Cytokine

authors： Hajizadeh Maleki B,Tartibian B,Mooren FC,FitzGerald LZ,Krüger K,Chehrazi M,Malandish A

更新日期：2018-02-01 00:00:00

abstract：:The eph family is the largest subfamily of receptor tyrosine kinases (RTKs). Members of this subfamily display specific expression in the developing and adult brain. Recently, cDNAs encoding membrane bound ligands for these receptors have been identified which we have termed LERKs (ligand for eph-related kinases). We ...

journal_title：Cytokine

authors： Kozlosky CJ,VandenBos T,Park L,Cerretti DP,Carpenter MK

更新日期：1997-08-01 00:00:00

abstract：:Immunoincompetence is a profound problem in end-stage renal failure patients undergoing hemodialysis, and chronic inflammation with altered serum levels of inflammation markers has been reported. Gene expression patterns have had little relevance for leukocyte research so far because of limitations in transcript level...

journal_title：Cytokine

authors： Knerr K,Füth R,Hemsen P,Mohné W,Heinig A,Kleophas W,Scherbaum WA,Martin S

更新日期：2005-05-07 00:00:00

abstract：BACKGROUND:Inflammatory periodontal diseases are caused by interaction between gram negative, anaerobic bacteria and host response. Persistent infection of Pseudomonas aeruginosa in cystic fibrosis (CF) patients also cause increased pro-inflammatory response and the imbalance of pro- and anti-inflammatory response in b...

journal_title：Cytokine

authors： Duruel O,Berker E,Özşin-Özler C,Gharibzadeh-Hızal M,Gürpınar Ö,Eryılmaz-Polat S,Ataman-Duruel ET,Tan Ç,Karabulut E,Tekçiçek M,Eser ÖK,Kiper N,Tezcan İ

更新日期：2020-03-01 00:00:00

abstract：:In this study two different aspects of tumour necrosis factor alpha (TNF-alpha) and interleukin 1 (IL-1) in locally induced murine streptococcal cell wall arthritis (SCW) were investigated. First, the kinetics and interdependence of TNF-alpha and IL-1 release; and second; their involvement in inflammation and cartilag...

journal_title：Cytokine

authors： Kuiper S,Joosten LA,Bendele AM,Edwards CK 3rd,Arntz OJ,Helsen MM,Van de Loo FA,Van den Berg WB

更新日期：1998-09-01 00:00:00

abstract：:Psoriatic fibroblasts produce enhanced amounts of IL-6 in vitro. This state of activation may reflect an altered expression of cytokine receptors, involved in auto/paracrine induction of IL-6. Cultures of dermal fibroblasts derived from lesional psoriatic (PP) and normal control (NN) skin were therefore analysed for t...

journal_title：Cytokine

authors： Debets R,Hegmans JP,Buurman WA,Benner R,Prens EP

更新日期：1996-01-01 00:00:00