Abstract:
:Cardiothoracic surgery posits an arrangement of large, significant hemodynamic, and physiologic alterations upon the human body, which predisposes a patient to develop pathology. The care of these patients in the postoperative realm requires an astute physician with deep understanding of the cardiopulmonary system, who is able to address subtle developing problems promptly, before the patient suffers further sequelae. In this review, we describe the presentation and management of an assortment of important complications which occur in the pulmonary system. In addition, we aim to shed better light upon how the physiology of a patient responds to the condition of cardiothoracic surgery.
journal_name
Lungjournal_title
Lungauthors
Tanner TG,Colvin MOdoi
10.1007/s00408-020-00405-7subject
Has Abstractpub_date
2020-12-01 00:00:00pages
889-896issue
6eissn
0341-2040issn
1432-1750pii
10.1007/s00408-020-00405-7journal_volume
198pub_type
杂志文章,评审相关文献
LUNG文献大全abstract::The pathophysiology of cough variant asthma is poorly understood. In particular, the mechanisms that cause different symptoms in typical asthma (in which wheeze predominates) compared with cough variant asthma (in which cough predominates) have not been determined. Traditional explanations include higher wheezing thre...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-011-9348-6
更新日期:2012-02-01 00:00:00
abstract::Reports regarding smoking differences in α-klotho expression have provided conflicting results. In the current study we focused on the influence of smoking intensity to serum levels of the aging molecule α-klotho in healthy smokers. 40 middle aged healthy smokers without airway obstruction or restriction were selected...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-016-9944-6
更新日期:2017-02-01 00:00:00
abstract::In severe asthma attacks beta 2-sympathomimetics lose part of their therapeutic efficiency. To elucidate this loss of efficiency in an experimental model we compared the relaxant potency of salbutamol (SAL), fenoterol (FEN), formoterol (FOR), and (-)-isoprenaline (ISO) in guinea pig tracheae partially and maximally pr...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00174319
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:Nicorandil is a hybrid between nitrates and KATP channel opener activators. The aim of this study was to evaluate the nicorandil's effects on ischemia-reperfusion (IR) lung injury and examine the mechanism of its effects. METHODS:Isolated rat lungs were divided into 6 groups. In the sham group, the lungs were ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00339-0
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:This study was designed to review outcomes of once- (QD) versus twice-daily (BID) radiotherapy (RT) for limited stage small-cell lung cancer (L-SCLC) treated at Dana-Farber Cancer Institute/Brigham and Women's Hospital. METHODS:We reviewed records for all patients with L-SCLC treated with radical chemoradiothe...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-013-9518-9
更新日期:2014-02-01 00:00:00
abstract::Respiratory virus infections leads to coughing, sneezing, and increases in reflex parasympathetic bronchoconstriction and secretions. These responses to viral infection are exclusively or largely secondary to changes in the function of the nervous system. For many with underlying airway pathologies such as asthma and ...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-015-9832-5
更新日期:2016-02-01 00:00:00
abstract::It is well known that exposure to hyperoxia results in lung inflammation and damage, which leads to the development of chronic lung disease. Previous studies have shown increased activities of antioxidant enzymes (AOE) in lung tissue from animals exposed to hyperoxia. We propose the hypothesis that the fetal type II p...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000006
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Survival implications of pre-transplant antibodies to human leukocyte antigens prior to lung transplantation (LTx) in adult cystic fibrosis (CF) patients are unknown. METHODS:Data from the United Network for Organ Sharing Registry (1987-2013) were used to compare survival differences in adult CF patients wi...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-016-9861-8
更新日期:2016-06-01 00:00:00
abstract::High concentrations of tumor necrosis factor-a (TNF), as well as excess of polymorphonuclear leukocytes (PMNs), are present in pleural fluid of patients with complicated parapneumonic effusion (CPPE). Several studies have shown that PMNs are capable of secreting TNF. However, the correlation between levels of TNF and ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000100
更新日期:2002-01-01 00:00:00
abstract::Eosinophils have been shown to play a role in allergen-induced airway responses. The aim in this study was to examine the effects of TAK-661, a newly developed product as a specific inhibitory agent of eosinophil chemotaxis, on antigen-induced asthmatic responses in allergic sheep model. Seven Ascaris-sensitive, "dual...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000090
更新日期:2002-01-01 00:00:00
abstract::Overlap syndrome and represents a complex clinical condition in pulmonary medicine. We discuss in this letter factors related with mortality after long-term effects CPAP and key differences between hypercapnic versus hypoxemic overlap patients. ...
journal_title:Lung
pub_type: 评论,信件
doi:10.1007/s00408-014-9613-6
更新日期:2014-10-01 00:00:00
abstract::Surfactant is not a homogeneous material and can be separated into subtypes. Subtype conversion is clinically important because it is thought to occur naturally and because surface activity varies depending on the subtype. Fibrinogen, a naturally occurring serum protein, is known to affect this conversion. In this stu...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/pl00007569
更新日期:1997-01-01 00:00:00
abstract::The severity of chronic obstructive pulmonary disease (COPD) is evaluated not only by airflow limitation but also by factors such as exercise capacity and body mass index. Recent advances in CT technology suggest that it might be a useful tool for evaluating the severity of the disease components of COPD. The aim of t...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-008-9071-0
更新日期:2008-05-01 00:00:00
abstract::Difficult weaning is fortunately a rare occurrence in mechanically ventilated patients in ICU. When faced with this problem, a vast number of factors must be carefully considered simultaneously: physiological adjustment, technical problems (tubing, circuit resistances, . . .) [13]. The most promising approach to diffi...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/BF02718216
更新日期:1990-01-01 00:00:00
abstract::Binding characteristics of the alpha 1-adrenergic radioloigand [3H]prazosin, and the muscarinic cholinergic radioligand, [3H]quinuclidinyl benzilate, were determined both in intact cell preparations of rat alveolar type II pneumocytes (TIIPs) and in membrane preparations of rat lung tissue. Binding in adult and neonat...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00165701
更新日期:1993-01-01 00:00:00
abstract::Gastro-oesophageal reflux disease (GORD) is generally considered one of the three main causes of chronic cough, along with asthma and nasal disease. The diagnosis of GORD is often based upon a successful trial of anti-acid treatment however GORD is a complex condition taking many forms. Only recently have studies star...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-009-9210-2
更新日期:2010-01-01 00:00:00
abstract::The effect of azelastine and some selected compounds on ciliary beating frequency (CBF) was investigated in vitro using human mucosal samples and in vivo using anesthetized guinea pigs. Further influence of azelastine on mucus secretion was evaluated in mice and on mucociliary clearance in anesthetized rabbits. Azelas...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00174117
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:Lymphangioleiomyomatosis (LAM) is a rare, progressive, frequently lethal cystic lung disease that almost exclusively affects women. Prognostic information in LAM has been limited by small numbers and heterogeneous study methodology. Early retrospective cohorts cited 5- and 10-year mortality of 40 and 80 %, resp...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-012-9419-3
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:The aim was to investigate whether maintenance therapy (MT) is sufficient or not to improve overall survival (OS) and progress-free survival (PFS) of advanced non-small cell lung cancer (NSCLC) patients. METHODS:Randomized controlled trials (RCTs) published between 1990 and 2013 were retrieved from PubMed, EMB...
journal_title:Lung
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00408-015-9758-y
更新日期:2015-10-01 00:00:00
abstract::Along with upper airway cough syndrome (formerly, postnasal drip syndrome) and eosinophilic airway inflammation (asthma, nonasthmatic eosinophilic bronchitis), gastroesophageal reflux disease (GERD) is generally considered among the most common etiologies of chronic cough. Indeed, cough management guidelines published...
journal_title:Lung
pub_type:
doi:10.1007/s00408-013-9528-7
更新日期:2014-02-01 00:00:00
abstract::Patients with pleural effusions frequently present a diagnostic and therapeutic challenge. The diagnosis is based on the interpretation of the results of thoracentesis or pleural biopsy. When a malignant tumor metastasizes to the pleura, tumor cells can be seeded over the mesothelial surface or in the subserous layer....
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s004080000040
更新日期:2000-11-01 00:00:00
abstract::Six European treatment centers contributed to a controlled trial to study nocturnal hypoxemia in COPD patients having daytime PaO2 of 60-70 mmHg. The trial is composed of two parts: first, patients inclusion, taking men aged under 70 years, excluding sleep apnea syndrome and all other concomitant pathologies leading t...
journal_title:Lung
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/BF02718206
更新日期:1990-01-01 00:00:00
abstract::Cryoextraction is a procedure for recanalization of obstructed airways caused by exophytic growing tumors. Biopsy samples obtained with this method can be used for histological diagnosis. The objective of this study was to evaluate the parameters influencing the size of cryobiopsies in an in vitro animal model. New fl...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-009-9156-4
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Pulmonary arterial hypertension (PAH) is a deadly disease, and the molecular mechanism of PAH has not been clarified clearly. The objective of this study was to identify possible biomarkers and explore the potential mechanisms of Schistosoma-induced PAH. METHODS:GSE49114 RNA-Seq data developed from mouse wh...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-017-9999-z
更新日期:2017-06-01 00:00:00
abstract::Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease (COPD), which is characterized by progressive destruction of alveolar parenchyma with persistent inflammation of the small airways. Such destruction in the distal respiratory tract is irreversible and irreparable. All-trans-retinoic ...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-012-9438-0
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:Acute exacerbations (AE) in patients with COPD are associated with a decline in lung function, increased risk of hospitalization, and mortality. In this cross-sectional study we tested whether the level of objectively measured daily physical activity and exercise capacity are associated with the number of COPD ...
journal_title:Lung
pub_type: 杂志文章,多中心研究
doi:10.1007/s00408-014-9673-7
更新日期:2015-02-01 00:00:00
abstract::It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortalit...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0164-0
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Mannitol is a novel osmotic indirect bronchial challenge agent used to aid asthma diagnosis and management and is thought to reflect underlying inflammatory processes in asthma. Our objective was to evaluate relationships between mannitol airway hyperresponsiveness (AHR) and other measures of airway inflamma...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-012-9396-6
更新日期:2012-10-01 00:00:00
abstract::In recent years the alveolar macrophage has been found to play a central role in interstitial lung disease. Pulmonary histiocytosis X is characterized by infiltrating fibroblasts, mononuclear cells, and CD-1-positive Langerhans cells. Bronchoalveolar lavage (BAL) fluid displays an increase of CD-1-positive cells and a...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/BF00175659
更新日期:1995-01-01 00:00:00
abstract::Methacholine challenge testing (MCT) is widely used to assess airway hyperresponsiveness (AHR). Traditionally, a 20% or greater decline in forced expiratory volume in 1 (FEV(1)) is the primary outcome measure. We examined whether the inclusion of wheeze detection as outcome measure influenced the categorical interpret...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-005-2575-y
更新日期:2006-05-01 00:00:00