Correction to: Inhibition of C3a/C3aR Axis in Diverse Stages of Ulcerative Colitis Affected the Prognosis of UC by Modulating the Pyroptosis and Expression of Caspase-11.

abstract：:Bee venom (BV) is used in folk medicine to treat arthritis. It has antiinflammatory effects in animal models of rheumatic disease. We have studied the effects of BV on human neutrophil production of superoxide (O2-) and hydrogen peroxide, finding potent, nontoxic, dose-dependent production inhibition. Melittin, the ma...

journal_title：Inflammation

authors： Somerfield SD,Stach JL,Mraz C,Gervais F,Skamene E

更新日期：1986-06-01 00:00:00

abstract：:A rat sponge implant model was used to examine the role of protein kinase C (PKC) in angiogenesis. Neovascular response was determined by measurements of relative sponge blood flow by a 133Xe clearance technique and confirmed histologically. Morphometric analysis was used to quantitate the amount of fibrovascular grow...

journal_title：Inflammation

authors： Hu DE,Fan TP

更新日期：1995-02-01 00:00:00

abstract：:IL-17-producing Th17 cells and IFN-γ and IL-17 double-producing Th1/17 cells have been identified as the pathogenic cells in inflammatory bowel disease (IBD). Retinoic acid-related orphan receptor γt (RORγt) is a master regulator for the differentiation and activation of Th17 and Th1/17 cells. We discovered a novel or...

journal_title：Inflammation

authors： Igaki K,Nakamura Y,Komoike Y,Uga K,Shibata A,Ishimura Y,Yamasaki M,Tsukimi Y,Tsuchimori N

更新日期：2019-02-01 00:00:00

abstract：:To study the efficacy and mechanism of Salvia miltiorrhizae injection in the treatment of severe acute pancreatitis. SAP rat models were prepared and randomly divided into model control group and treated group. The sham-operated group was also set. At 3, 6 and 12 h after operation, the mortality rate, ascitic volumes,...

journal_title：Inflammation

authors： Zhang R,Zhang X,Zhang J,Wu J,Ye Q,Xu R,Ye J,Fang X,Jin L,He J,Yuan W

更新日期：2009-04-01 00:00:00

abstract：:Aberrant activation of the NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inflammasome, triggers a pathogenic inflammatory response in many inherited neurodegenerative disorders. Inflammation has recently been associated with valosin-containing protein (VCP)-associated diseases, caused by mi...

journal_title：Inflammation

authors： Nalbandian A,Khan AA,Srivastava R,Llewellyn KJ,Tan B,Shukr N,Fazli Y,Kimonis VE,BenMohamed L

更新日期：2017-02-01 00:00:00

abstract：:Baicalein shows anti-inflammatory effects in human rheumatoid arthritis fibroblast-like synoviocytes (RAFLS). Considering its anti-proliferatory effects on various cancer cells, we investigated the effects of baicalein on interleukin-1 beta (IL-1β)-induced proliferation of human RAFLS. Cell proliferation was examined ...

journal_title：Inflammation

authors： Chen S,Yang Y,Feng H,Wang H,Zhao R,Liu H

更新日期：2014-02-01 00:00:00

abstract：:We have previously reported the antifibrotic effects of pirfenidone (PD) in the bleomycin (BL)-hamster model of lung fibrosis. Since the development of fibrosis is generally preceded by acute lung inflammation, the present study was conducted to find out if dietary intake of PD (0.5%) has any effects on BL-induced lun...

journal_title：Inflammation

authors： Iyer SN,Hyde DM,Giri SN

更新日期：2000-10-01 00:00:00

abstract：:Numerous cytokines, including vascular endothelial growth factor (VEGF), are implicated in the pathogenesis of sepsis. While overexpression of VEGF produces pulmonary capillary leak, the role of VEGF in sepsis is less clear. We investigated VEGF in sepsis, utilizing a VEGF trap (VEGF(T)). Polymicrobial sepsis was indu...

journal_title：Inflammation

authors： Nolan A,Weiden MD,Thurston G,Gold JA

更新日期：2004-10-01 00:00:00

abstract：:Lipopolysaccharide (LPS) can activate endothelial cells and induce inflammatory injury. Toll-like receptor-4 (TLR-4) is integrally involved in LPS signaling and has a requisite role in the activation of nuclear factor (NF)-κB. A number of studies have demonstrated the cytoprotective action of perfluorocarbon (PFC) bot...

journal_title：Inflammation

authors： Xu S,Wang P,Wei K,Liu F,Liang Z,Zhao X,Li A,Chen L

更新日期：2013-04-01 00:00:00

abstract：:Previous reports showed that Maresin 1 (MaR1) possessed organ protection effects and could attenuate acute lung injury. Here, we aim to figure out whether MaR1 can maintain the permeability of lung epithelial cells by regulating the expression of tight junction protein during lung injury. Monolayer of murine lung epit...

journal_title：Inflammation

authors： Chen L,Liu H,Wang Y,Xia H,Gong J,Li B,Yao S,Shang Y

更新日期：2016-12-01 00:00:00

abstract：:D-limonene epoxidation generates (+)-limonene epoxide, an understudied compound in the pharmacologically point of view. Herein, we investigated the anti-inflammatory and antinociceptive potentialities of (+)-limonene epoxide and suggested a mechanism of action. The anti-inflammatory potential was analyzed using agents...

journal_title：Inflammation

authors： de Almeida AA,Silva RO,Nicolau LA,de Brito TV,de Sousa DP,Barbosa AL,de Freitas RM,Lopes LD,Medeiros JR,Ferreira PM

更新日期：2017-04-01 00:00:00

abstract：:Chemerin is shown to be associated with inflammation which is involved in the pathogenesis of diabetic nephropathy. This study aims to determine whether rosiglitazone and pioglitazone ameliorate renal function through an effect on the expression of chemerin and ChemR23 in streptozotocin-induced diabetic rats. The rats...

journal_title：Inflammation

authors： Hu W,Yu Q,Zhang J,Liu D

更新日期：2012-08-01 00:00:00

abstract：:We investigated the molecular mechanisms underlying the role of miRNAs in the pathogenesis of psoriasis to discover novel potential diagnostic markers and treatment targets. We screened Chinese Han individuals using gene chip technology to identify differentially expressed miRNAs in the epidermal tissue of lesions fro...

journal_title：Inflammation

authors： Wang Y,Yu X,Wang L,Ma W,Sun Q

更新日期：2018-12-01 00:00:00

abstract：:Streptococcus suis serotype 2 (SS2) is an emerging zoonosis, and meningitis is the most frequent clinical manifestation, but mechanism of its virulent factor, enolase (Eno), is unknown in meningitis. In this study, Eno was inducibly expressed and added to an in vitro Transwell co-culture model of the blood-brain barri...

journal_title：Inflammation

authors： Sun Y,Li N,Zhang J,Liu H,Liu J,Xia X,Sun C,Feng X,Gu J,Du C,Han W,Lei L

更新日期：2016-04-01 00:00:00

abstract：:Recombinant human tumor necrosis factor-alpha (rTNF) stimulated increased generation of superoxide anion (O2-) by human neutrophils in a concentration-dependent fashion. Preincubation of human neutrophils with rTNF (2.2-2200 units/ml) for 10 min enhanced the subsequent generation of O2- in response to C5a and f-Met-Le...

journal_title：Inflammation

authors： Bajaj MS,Kew RR,Webster RO,Hyers TM

更新日期：1992-06-01 00:00:00

abstract：:Rabbits were injected intramuscularly with cortisone acetate (2 mg/kg) on alternate days. Six days after the first injection these rabbits and controls were injected intradermally in multiple sites with BCG (the vaccine strain of tubercle bacillus). Periodically, over the next 2 months, the resulting lesions were meas...

journal_title：Inflammation

authors： McCue RE,Dannenberg AM Jr,Higuchi S,Sugimoto M

更新日期：1978-06-01 00:00:00

abstract：:Recent studies show that nuclear factor-kappa B (NF-κB) signaling pathway plays a key role in contributing to the development of lipopolysaccharide (LPS)-induced acute lung injury (ALI). Tetrahydrocoptisine is one of the main active components of Chelidonium majus L. and has been described to be effective in suppressi...

journal_title：Inflammation

authors： Li W,Huang H,Niu X,Fan T,Hu H,Li Y,Yao H,Li H,Mu Q

更新日期：2014-12-01 00:00:00

abstract：:The biological effects of asiatic acid (AA) on spinal cord injury (SCI)-induced acute lung injury (ALI) have not been investigated. We aimed to investigate the therapeutic efficacy and molecular mechanisms of AA on SCI-induced ALI. One-hundred and fifty Sprague-Dawley rats were randomly assigned to five groups: sham, ...

journal_title：Inflammation

authors： Jiang W,Li M,He F,Yao W,Bian Z,Wang X,Zhu L

更新日期：2016-12-01 00:00:00

abstract：:Berberine (Ber), the major constituent of Coptidis Rhizoma, possesses anti-inflammatory properties. In this study, we investigated the effects of Ber on cigarette smoke (CS)-mediated acute lung inflammation. C57BL/6 mice (6-8 weeks) were exposed to CS to induce acute lung injury. Ber was used to pretreat CS-exposed mi...

journal_title：Inflammation

authors： Lin K,Liu S,Shen Y,Li Q

更新日期：2013-10-01 00:00:00

abstract：:The effects were studied of the non-specific phosphodiesterase inhibitor, theophylline (37.5-300 microM), on intracellular levels of cyclic adenosine monophosphate (cAMP) and superoxide generation following exposure of human neutrophils to four different stimuli of neutrophil membrane-associated oxidative metabolism, ...

journal_title：Inflammation

authors： Mahomed AG,Theron AJ,Anderson R,Feldman C

更新日期：1998-12-01 00:00:00

abstract：:The effect of interleukin-1 beta (IL-1 beta) on the expression of cyclooxygenase-1 and -2 (COX-1 and COX-2) mRNA and its relation to prostaglandin E2 (PGE2) biosynthesis in human gingival fibroblasts was studied. IL-1 beta increased levels of mRNA for COX-2 whereas the COX-1 mRNA level was unaffected. The increased CO...

journal_title：Inflammation

authors： Yucel-Lindberg T,Ahola H,Nilsson S,Carlstedt-Duke J,Modéer T

更新日期：1995-10-01 00:00:00

abstract：:In the present study the content of substance P (SP)-, neurokinin A (NKA)-, calcitonin gene-related peptide (CGRP)- and neuropeptide Y (NPY)-like immunoreactivity (-LI) was measured in rats cerebrospinal fluid (CSF), plasma and perfusates (PF) from both elbow enthesis during acute inflammation. Either substance P, SP,...

journal_title：Inflammation

authors： Haker E,Theodorsson E,Lundeberg T

更新日期：1997-02-01 00:00:00

abstract：:Diabetic retinopathy shares some similarity with chronic inflammation and Müller cells dysfunction may play an important role in its initiation and progression since these cells are thought to be a major source of inflammatory factors. The goal of this study was to examine the effect of cytokines on human retinal Müll...

journal_title：Inflammation

authors： Liu X,Ye F,Xiong H,Hu D,Limb GA,Xie T,Peng L,Yang W,Sun Y,Zhou M,Song E,Zhang DY

更新日期：2014-10-01 00:00:00

abstract：:Macrophage polarization is a dynamic and integral process of tissue inflammation and remodeling. Here we demonstrate an important role of Aurora kinase A in the regulation of inflammatory M1 macrophage polarization. We found that there was an elevated expression of Aurora-A in M1 macrophages and inhibition of Aurora-A...

journal_title：Inflammation

authors： Ding L,Gu H,Gao X,Xiong S,Zheng B

更新日期：2015-04-01 00:00:00

abstract：:Icariin is a flavonoid isolated from the traditional Chinese herbal medicine Epimedium brevicornum Maxim and has been reported to be effective for the treatment of a variety of cardiovascular diseases. The aim of the present study was to investigate the effect and mechanism of icariin on atherosclerosis (AS) using a h...

journal_title：Inflammation

authors： Hu Y,Sun B,Liu K,Yan M,Zhang Y,Miao C,Ren L

更新日期：2016-02-01 00:00:00

abstract：:The bacterial keratitis causes viability loss and apoptosis in the corneal epithelial cells (CECs). The cyanidin-3-O-glucoside (C3G) benefits visual system and also possess anti-bacterial and anti-inflammatory potentials. In the current study, the effects of C3G on human CECs (HCECs) against bacterial lipopolysacchari...

journal_title：Inflammation

authors： Li X,Sun M,Long Y

更新日期：2020-06-01 00:00:00

abstract：:A heat-stable factor present in extracts of human blood leukocytes is capable of lysing young Staphylococcus aureus at pH 5.0. Lysis is characterized by breakdown of cell-wall components as judged by electron microscopic and biochemical analysis. The leukocyte extracts can be replaced by a variety of agents known to i...

journal_title：Inflammation

authors： Lahav M,Ginsburg I

更新日期：1977-06-01 00:00:00

abstract：:In the present study, the anti-inflammatory effect of piperine was investigated on monosodium urate crystal-induced inflammation in mice, an experimental model for gouty arthritis, and compared it with that of the nonsteroidal anti-inflammatory drug, indomethacin. The levels of lysosomal enzymes, lipid peroxidation, t...

journal_title：Inflammation

authors： Sabina EP,Nagar S,Rasool M

更新日期：2011-06-01 00:00:00

abstract：:Interleukin-10 (IL-10) is a pleiotropic cytokine and plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Unlike IL-10 protein, few studies have focused on the potential association between IL-10 receptor (IL-10R) and SLE. The purpose of this study was to examine the association of a sing...

journal_title：Inflammation

authors： Peng H,Liu CY,Zhou M,Wen PF,Zhang M,Qiu LJ,Ni J,Liang Y,Pan HF,Ye DQ

更新日期：2013-12-01 00:00:00

abstract：:Human neutrophils were demonstrated to possess interleukin-2 receptor (IL-2R) beta and gamma chains, not alpha chain and the binding of IL-2 to the IL-2R beta chain on neutrophils plays an important regulatory role in neutrophil functions. We have investigated in this study the hypothesis that recombinant human IL-2 (...

journal_title：Inflammation

authors： Li J,Gyorffy S,Lee S,Kwok CS

更新日期：1996-08-01 00:00:00