当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES期刊下所有文献 > Investigation of a Staphylococcus argenteus Strain Involved in a Chronic Prosthetic-Joint Infection.

Investigation of a Staphylococcus argenteus Strain Involved in a Chronic Prosthetic-Joint Infection.

Abstract：

:Staphylococcus argenteus is an emerging species responsible for infections comparable to those induced by Staphylococcus aureus. It has been involved in few chronic or persistent infections so far. In this study, we described a case of a persistent prosthetic-joint infection (PJI) affecting a young woman. We investigated in vitro the virulence traits of the incriminated S. argenteus strain (bone cell invasion, biofilm formation and induction of inflammation) and analyzed its genome, in comparison with two other strains of S. argenteus and two S. aureus isolates. It appeared that this S. argenteus PJI strain combined biofilm formation, osteoblast invasion and intracellular persistence abilities together with genes potentially involved in the escape of the host immune defenses, which might explain the chronicization of the infection.

journal_name

Int J Mol Sci

journal_title

International journal of molecular sciences

authors

Diot A,Dyon-Tafani V,Bergot M,Tasse J,Martins-Simões P,Josse J,Valour F,Laurent F

doi

10.3390/ijms21176245

subject

Has Abstract

pub_date

2020-08-28 00:00:00

issue

17

issn

1422-0067

pii

ijms21176245

journal_volume

21

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES文献大全
  • Integrative Analysis of Regulatory Module Reveals Associations of Microgravity with Dysfunctions of Multi-body Systems and Tumorigenesis.

    abstract：:Previous studies have demonstrated that microgravity could lead to health risks. The investigation of the molecular mechanisms from the aspect of systems biology has not been performed yet. Here, we integratively analyzed transcriptional and post-transcriptional regulations based on gene and miRNA expression profiles ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21207585

    authors： Yuan M,Liu H,Zhou S,Zhou X,Huang YE,Hou F,Jiang W

    更新日期：2020-10-14 00:00:00

  • FGF21 Protects against Aggravated Blood-Brain Barrier Disruption after Ischemic Focal Stroke in Diabetic db/db Male Mice via Cerebrovascular PPARγ Activation.

    abstract：:Recombinant fibroblast growth factor 21 (rFGF21) has been shown to be potently beneficial for improving long-term neurological outcomes in type 2 diabetes mellitus (T2DM) stroke mice. Here, we tested the hypothesis that rFGF21 protects against poststroke blood-brain barrier (BBB) damage in T2DM mice via peroxisome pro...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21030824

    authors： Jiang Y,Lin L,Liu N,Wang Q,Yuan J,Li Y,Chung KK,Guo S,Yu Z,Wang X

    更新日期：2020-01-28 00:00:00

  • Cocoa and Grape Seed Byproducts as a Source of Antioxidant and Anti-Inflammatory Proanthocyanidins.

    abstract：:Phenolic compounds, which are secondary plant metabolites, are considered an integral part of the human diet. Physiological properties of dietary polyphenols have come to the attention in recent years. Especially, proanthocyanidins (ranging from dimers to decamers) have demonstrated potential interactions with biologi...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms18020376

    authors： Cádiz-Gurrea ML,Borrás-Linares I,Lozano-Sánchez J,Joven J,Fernández-Arroyo S,Segura-Carretero A

    更新日期：2017-02-10 00:00:00

  • Endoglin Targeting: Lessons Learned and Questions That Remain.

    abstract：:Approximately 30 years ago, endoglin was identified as a transforming growth factor (TGF)-β coreceptor with a crucial role in developmental biology and tumor angiogenesis. Its selectively high expression on tumor vessels and its correlation with poor survival in cancer patients led to the exploration of endoglin as a ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms22010147

    authors： Liu Y,Paauwe M,Nixon AB,Hawinkels LJAC

    更新日期：2020-12-25 00:00:00

  • Growth Hormone Deficiency Following Traumatic Brain Injury.

    abstract：:Traumatic brain injury (TBI) is fairly common and annually affects millions of people worldwide. Post traumatic hypopituitarism (PTHP) has been increasingly recognized as an important and prevalent clinical entity. Growth hormone deficiency (GHD) is the most common pituitary hormone deficit in long-term survivors of T...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms20133323

    authors： Kgosidialwa O,Hakami O,Muhammad Zia-Ul-Hussnain H,Agha A

    更新日期：2019-07-06 00:00:00

  • Functional Mechanisms Underlying the Antimicrobial Activity of the Oryza sativa Trx-like Protein.

    abstract：:Plants are constantly subjected to a variety of environmental stresses and have evolved regulatory responses to overcome unfavorable conditions that might reduce or adversely change a plant's growth or development. Among these, the regulated production of reactive oxygen species (ROS) as a signaling molecule occurs du...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms20061413

    authors： Park SC,Kim IR,Hwang JE,Kim JY,Jung YJ,Choi W,Lee Y,Jang MK,Lee JR

    更新日期：2019-03-20 00:00:00

  • Non-Linear Quantitative Structure⁻Activity Relationships Modelling, Mechanistic Study and In-Silico Design of Flavonoids as Potent Antioxidants.

    abstract：:In this work, we developed quantitative structure-activity relationships (QSAR) models for prediction of oxygen radical absorbance capacity (ORAC) of flavonoids. Both linear (partial least squares-PLS) and non-linear models (artificial neural networks-ANNs) were built using parameters of two well-established antioxida...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms20092328

    authors： Žuvela P,David J,Yang X,Huang D,Wong MW

    更新日期：2019-05-10 00:00:00

  • Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions.

    abstract：:Polyphosphoinositides (PPIns) are a family of seven lipid messengers that regulate a vast array of signalling pathways to control cell proliferation, migration, survival and differentiation. PPIns are differentially present in various sub-cellular compartments and, through the recruitment and regulation of specific pr...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms20122991

    authors： Fiume R,Faenza I,Sheth B,Poli A,Vidalle MC,Mazzetti C,Abdul SH,Campagnoli F,Fabbrini M,Kimber ST,Mariani GA,Xian J,Marvi MV,Mongiorgi S,Shah Z,Divecha N

    更新日期：2019-06-19 00:00:00

  • Schiff Base Ancillary Ligands in Bis(diimine) Copper(I) Dye-Sensitized Solar Cells.

    abstract：:Five 6,6'-dimethyl-2,2'-bipyridine ligands bearing N-arylmethaniminyl substituents in the 4- and 4'-positions were prepared by Schiff base condensation in which the aryl group is Ph (1), 4-tolyl (2), 4- t BuC6H4 (3), 4-MeOC6H4 (4), and 4-Me2NC6H4 (5). The homoleptic copper(I...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21051735

    authors： Lüthi E,Forero Cortés PA,Prescimone A,Constable EC,Housecroft CE

    更新日期：2020-03-03 00:00:00

  • Structural Identification of Antibacterial Lipids from Amazonian Palm Tree Endophytes through the Molecular Network Approach.

    abstract：:A library of 197 endophytic fungi and bacteria isolated from the Amazonian palm tree Astrocaryum sciophilum was extracted and screened for antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). Four out of five antibacterial ethyl acetate extracts were also cytotoxic for the MRC-5 cells lin...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms20082006

    authors： Barthélemy M,Elie N,Pellissier L,Wolfender JL,Stien D,Touboul D,Eparvier V

    更新日期：2019-04-24 00:00:00

  • Glioblastoma Cells Do Not Affect Axitinib-Dependent Senescence of HUVECs in a Transwell Coculture Model.

    abstract：:Axitinib is an orally available inhibitor of tyrosine kinases, with high specificity for vascular endothelial growth factor receptors (VEGFRs) 1, 2, and 3. It is approved for the treatment of advanced renal cell carcinoma and is in phase II clinical trials for recurrent glioblastoma (GBM). GBM is a brain tumor peculia...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21041490

    authors： Merolle M,Mongiardi MP,Piras M,Levi A,Falchetti ML

    更新日期：2020-02-21 00:00:00

  • A Systematic Evaluation of Blood Serum and Plasma Pre-Analytics for Metabolomics Cohort Studies.

    abstract：:The recent thriving development of biobanks and associated high-throughput phenotyping studies requires the elaboration of large-scale approaches for monitoring biological sample quality and compliance with standard protocols. We present a metabolomic investigation of human blood samples that delineates pitfalls and g...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms17122035

    authors： Jobard E,Trédan O,Postoly D,André F,Martin AL,Elena-Herrmann B,Boyault S

    更新日期：2016-12-05 00:00:00

  • The neuroprotective functions of transforming growth factor beta proteins.

    abstract：:Transforming growth factor beta (TGF-β) proteins are multifunctional cytokines whose neural functions are increasingly recognized. The machinery of TGF-β signaling, including the serine kinase type transmembrane receptors, is present in the central nervous system. However, the 3 mammalian TGF-β subtypes have distinct ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms13078219

    authors： Dobolyi A,Vincze C,Pál G,Lovas G

    更新日期：2012-01-01 00:00:00

  • RAGE Signaling in Melanoma Tumors.

    abstract：:Despite recent progresses in its treatment, malignant cutaneous melanoma remains a cancer with very poor prognosis. Emerging evidences suggest that the receptor for advance glycation end products (RAGE) plays a key role in melanoma progression through its activation in both cancer and stromal cells. In tumors, RAGE ac...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms21238989

    authors： Olaoba OT,Kadasah S,Vetter SW,Leclerc E

    更新日期：2020-11-26 00:00:00

  • Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1.

    abstract：:The mammalian target of rapamycin (mTOR) is the central regulator of mammalian cell growth, and is essential for the formation of two structurally and functionally distinct complexes: mTORC1 and mTORC2. mTORC1 can sense multiple cues such as nutrients, energy status, growth factors and hormones to control cell growth ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms17101636

    authors： Zheng L,Zhang W,Zhou Y,Li F,Wei H,Peng J

    更新日期：2016-09-29 00:00:00

  • Physical Mapping of Pm57, a Powdery Mildew Resistance Gene Derived from Aegilops searsii.

    abstract：:Powdery mildew caused by Blumeria graminis f. sp. tritici (Bgt) is one of many severe diseases that threaten bread wheat (Triticum aestivum L.) yield and quality worldwide. The discovery and deployment of powdery mildew resistance genes (Pm) can prevent this disease epidemic in wheat. In a previous study, we transferr...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms21010322

    authors： Dong Z,Tian X,Ma C,Xia Q,Wang B,Chen Q,Sehgal SK,Friebe B,Li H,Liu W

    更新日期：2020-01-03 00:00:00

  • What Is the Evolutionary Fingerprint in Neutrophil Granulocytes?

    abstract：:Over the years of evolution, thousands of different animal species have evolved. All these species require an immune system to defend themselves against invading pathogens. Nevertheless, the immune systems of different species are obviously counteracting against the same pathogen with different efficiency. Therefore, ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms21124523

    authors： Fingerhut L,Dolz G,de Buhr N

    更新日期：2020-06-25 00:00:00

  • Adult Renal Stem/Progenitor Cells Can Modulate T Regulatory Cells and Double Negative T Cells.

    abstract：:Adult Renal Stem/Progenitor Cells (ARPCs) have been recently identified in the human kidney and several studies show their active role in kidney repair processes during acute or chronic injury. However, little is known about their immunomodulatory properties and their capacity to regulate specific T cell subpopulation...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms22010274

    authors： Curci C,Picerno A,Chaoul N,Stasi A,De Palma G,Franzin R,Pontrelli P,Castellano G,Pertosa GB,Macchia L,Di Lorenzo VF,Sabbà C,Gallone A,Gesualdo L,Sallustio F

    更新日期：2020-12-29 00:00:00

  • Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation.

    abstract：:A key role of the mitochondrial Translocator Protein 18 KDa (TSPO) in neuroinflammation has been recently proposed. However, little is known about TSPO-activated pathways underlying the modulation of reactive microglia. In the present work, the TSPO activation was explored in an in vitro human primary microglia model ...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms20184467

    authors： Pozzo ED,Tremolanti C,Costa B,Giacomelli C,Milenkovic VM,Bader S,Wetzel CH,Rupprecht R,Taliani S,Settimo FD,Martini C

    更新日期：2019-09-10 00:00:00

  • A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4.

    abstract：:Early prediction of xenobiotic metabolism is essential for drug discovery and development. As the most important human drug-metabolizing enzyme, cytochrome P450 3A4 has a large active cavity and metabolizes a broad spectrum of substrates. The poor substrate specificity of CYP3A4 makes it a huge challenge to predict th...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms160714677

    authors： Dai ZR,Ai CZ,Ge GB,He YQ,Wu JJ,Wang JY,Man HZ,Jia Y,Yang L

    更新日期：2015-06-30 00:00:00

  • Chemically induced breast tumors in rats are detectable in early stages by contrast enhanced magnetic resonance imaging but not by changes in the acute-phase reactants in serum.

    abstract：:The present study was undertaken to develop a rat model for monitoring the early development of breast cancer. Twelve female rats were divided into two groups of six rats that were either treated with N-methyl-N-nitrosourea to induce breast cancer or with bacterial lipopolysaccharide to induce inflammation. Serum samp...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms12021030

    authors： Golbabapour S,Pang WW,George J,Pasupati T,Abdul-Rahman PS,Hashim OH

    更新日期：2011-02-07 00:00:00

  • Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection.

    abstract：:The current knowledge about neuroprotective mechanisms in humans after status epilepticus is scarce. One reason is the difficulty to measure possible mediators of these neuroprotective mechanisms. The dawn of microRNA detection in the cerebrospinal fluid (CSF) and the recent advancements in measuring proteins in the C...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms18030490

    authors： Körtvelyessy P,Huchtemann T,Heinze HJ,Bittner DM

    更新日期：2017-02-24 00:00:00

  • Special Issue on "The Tight Junction and Its Proteins: More than Just a Barrier".

    abstract：:For a long time, the tight junction (TJ) was known to form and regulate the paracellular barrier between epithelia and endothelial cell sheets. Starting shortly after the discovery of the proteins forming the TJ-mainly, the two families of claudins and TAMPs-several other functions have been discovered, a striking one...

    journal_title：International journal of molecular sciences

    pub_type： 社论

    doi：10.3390/ijms21134612

    authors： Krug SM,Fromm M

    更新日期：2020-06-29 00:00:00

  • Gestational Factors throughout Fetal Neurodevelopment: The Serotonin Link.

    abstract：:Serotonin (5-HT) is a critical player in brain development and neuropsychiatric disorders. Fetal 5-HT levels can be influenced by several gestational factors, such as maternal genotype, diet, stress, medication, and immune activation. In this review, addressing both human and animal studies, we discuss how these gesta...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms21165850

    authors： Hanswijk SI,Spoelder M,Shan L,Verheij MMM,Muilwijk OG,Li W,Liu C,Kolk SM,Homberg JR

    更新日期：2020-08-14 00:00:00

  • Is Upregulation of Aquaporin 4-M1 Isoform Responsible for the Loss of Typical Orthogonal Arrays of Particles in Astrocytomas?

    abstract：:The astrocytic endfoot membranes of the healthy blood-brain barrier-contacting the capillary-are covered with a large number of the water channel aquaporin 4 (AQP4). They form orthogonal arrays of particles (OAPs), which consist of AQP4 isoform M1 and M23. Under pathologic conditions, AQP4 is distributed over the whol...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms17081230

    authors： Fallier-Becker P,Nieser M,Wenzel U,Ritz R,Noell S

    更新日期：2016-07-29 00:00:00

  • Adipose-Derived Stem Cells in Cancer Progression: New Perspectives and Opportunities.

    abstract：:Growing importance has been attributed to interactions between tumors, the stromal microenvironment and adult mesenchymal stem cells. Adipose-derived stem cells (ASCs) are routinely employed in regenerative medicine and in autologous fat transfer procedures. To date, clinical trials have failed to demonstrate the pote...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章,评审

    doi：10.3390/ijms20133296

    authors： Scioli MG,Storti G,D'Amico F,Gentile P,Kim BS,Cervelli V,Orlandi A

    更新日期：2019-07-04 00:00:00

  • Antimicrobial Resistance Profile of Planktonic and Biofilm Cells of Staphylococcus aureus and Coagulase-Negative Staphylococci.

    abstract：:The objective of the present study was to determine the antimicrobial resistance profile of planktonic and biofilm cells of Staphylococcus aureus and coagulase-negative staphylococci (CoNS). Two hundred Staphylococcus spp. strains were studied, including 50 S. aureus and 150 CoNS strains (50 S. epidermidis, 20 S. haem...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms17091423

    authors： de Oliveira A,Cataneli Pereira V,Pinheiro L,Moraes Riboli DF,Benini Martins K,Ribeiro de Souza da Cunha Mde L

    更新日期：2016-09-01 00:00:00

  • The Expression and Clinical Outcome of pCHK2-Thr68 and pCDC25C-Ser216 in Breast Cancer.

    abstract：:Checkpoint kinase 2 (CHK2) and cell division cycle 25C (CDC25C) are two proteins involved in the DNA damage response pathway, playing essential roles in maintaining genome integrity. As one of the major hallmarks of abnormal cellular division, genomic instability occurs in most cancers. In this study, we identified th...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms17111803

    authors： Jiang H,Wang B,Zhang F,Qian Y,Chuang CC,Ying M,Wang Y,Zuo L

    更新日期：2016-10-28 00:00:00

  • InDel Marker Based Estimation of Multi-Gene Allele Contribution and Genetic Variations for Grain Size and Weight in Rice (Oryza sativa L.).

    abstract：:The market success of any rice cultivar is exceedingly dependent on its grain appearance, as well as its grain yield, which define its demand by consumers as well as growers. The present study was undertaken to explore the contribution of nine major genes, qPE9~1, GW2, SLG7, GW5, GS3, GS7, GW8, GS5, and GS2, in regula...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms20194824

    authors： Gull S,Haider Z,Gu H,Raza Khan RA,Miao J,Wenchen T,Uddin S,Ahmad I,Liang G

    更新日期：2019-09-28 00:00:00

  • Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.

    abstract：:Salivary gland dysfunction induces salivary flow reduction and a dry mouth, and commonly involves oral dysfunction, tooth structure deterioration, and infection through reduced salivation. This study aimed to investigate the impact of aging on the salivary gland by a metabolomics approach in an extensive aging mouse m...

    journal_title：International journal of molecular sciences

    pub_type： 杂志文章

    doi：10.3390/ijms22010404

    authors： Toan NK,Tai NC,Kim SA,Ahn SG

    更新日期：2021-01-02 00:00:00