Abstract：
:Over the years of evolution, thousands of different animal species have evolved. All these species require an immune system to defend themselves against invading pathogens. Nevertheless, the immune systems of different species are obviously counteracting against the same pathogen with different efficiency. Therefore, the question arises if the process that was leading to the clades of vertebrates in the animal kingdom-namely mammals, birds, amphibians, reptiles, and fish-was also leading to different functions of immune cells. One cell type of the innate immune system that is transmigrating as first line of defense in infected tissue and counteracts against pathogens is the neutrophil granulocyte. During the host-pathogen interaction they can undergo phagocytosis, apoptosis, degranulation, and form neutrophil extracellular traps (NETs). In this review, we summarize a wide spectrum of information about neutrophils in humans and animals, with a focus on vertebrates. Special attention is kept on the development, morphology, composition, and functions of these cells, but also on dysfunctions and options for cell culture or storage.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Fingerhut L,Dolz G,de Buhr Ndoi
10.3390/ijms21124523subject
Has Abstractpub_date
2020-06-25 00:00:00issue
12issn
1422-0067pii
ijms21124523journal_volume
21pub_type
杂志文章,评审abstract：:Studies have shown that the type II pyridoxal phosphate-dependent decarboxylase (PLP_deC) genes produce secondary metabolites and flavor volatiles in plants, and TDC (tryptophan decarboxylase), a member of the PLP_deC family, plays an important role in the biosynthesis of terpenoid indole alkaloids (TIAs). In this stu...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21010054
更新日期：2019-12-20 00:00:00
abstract：:Antioxidants are among the most popular health-protecting products, sold worldwide without prescription. Indeed, there are many reports showing the benefits of antioxidants but only a few questioning the possible harmful effects of these "drugs". The normal balance between antioxidants and free radicals in the body is...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms13022091
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journal_title：International journal of molecular sciences
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doi：10.3390/ijms20051123
更新日期：2019-03-05 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20205097
更新日期：2019-10-14 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20225789
更新日期：2019-11-18 00:00:00
abstract：:n/a. ...
journal_title：International journal of molecular sciences
pub_type： 评论,杂志文章
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更新日期：2017-05-05 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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更新日期：2019-06-15 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms12085157
更新日期：2011-01-01 00:00:00
abstract：:The melanin-inducing properties of cirsimaritin were investigated in murine B16F10 cells. Cirsimaritin is an active flavone with methoxy groups, which is isolated from the branches of Lithocarpus dealbatus. Tyrosinase activity and melanin content in murine B16F10 melanoma cells were increased by cirsimaritin in a dose...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms16048772
更新日期：2015-04-20 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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更新日期：2018-10-18 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
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更新日期：2017-07-15 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms150813247
更新日期：2014-07-29 00:00:00
abstract：:Botrytis cinerea is a pathogenic fungus that causes gray mold disease in a broad range of crops. The high intraspecific variability of B. cinerea makes control of this fungus very difficult. Here, we isolated a variant B05.10M strain from wild-type B05.10. The B05.10M strain showed serious defects in mycelial growth, ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21082912
更新日期：2020-04-21 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19010125
更新日期：2018-01-02 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20010169
更新日期：2019-01-04 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms17010098
更新日期：2016-01-13 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 临床试验,杂志文章
doi：10.3390/ijms20194710
更新日期：2019-09-23 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21218029
更新日期：2020-10-28 00:00:00
abstract：:Mathematical optimization framework allows the identification of certain nodes within a signaling network. In this work, we analyzed the complex extracellular-signal-regulated kinase 1 and 2 (ERK1/2) cascade in cardiomyocytes using the framework to find efficient adjustment screws for this cascade that is important fo...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20092179
更新日期：2019-05-02 00:00:00
abstract：:Acrylic bone cement is widely used in orthopedic surgery for treating various conditions of the bone and joints. Bone cement consists of methyl methacrylate (MMA), polymethyl methacrylate (PMMA), and benzoyl peroxide (BPO), functioning as a liquid monomer, solid phase, and polymerization initiator, respectively. Howev...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
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更新日期：2020-06-04 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20215460
更新日期：2019-11-01 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
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更新日期：2020-11-03 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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更新日期：2018-06-30 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
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更新日期：2012-10-22 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms151223389
更新日期：2014-12-16 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
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更新日期：2020-11-21 00:00:00
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更新日期：2020-03-04 00:00:00
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journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms17081270
更新日期：2016-08-19 00:00:00
