Immunotherapy for urothelial carcinoma: Metastatic disease and beyond.

abstract：AIM:We aimed to analyze surgical outcomes of open or laparoscopic adrenalectomy for solitary adrenal metastasis and assess the factors influencing survival. METHODS:We retrospectively reviewed our institutional clinicopathological database for cases of adrenalectomy for solitary adrenal metastasis from solid tumors be...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hatano K,Horii S,Nakai Y,Nakayama M,Kakimoto KI,Nishimura K

更新日期：2020-04-01 00:00:00

abstract：AIM:Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. METHOD:All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single ...

journal_title：Asia-Pacific journal of clinical oncology

authors： How SH,Ng TH,Kuan YC,Jamalludin AR,Fauzi AR

更新日期：2015-09-01 00:00:00

abstract：AIM:Complementary medicine (CAM) use in the cancer population is higher than the general population: some studies estimate up to 70%. Our Medicines Information Centre, in a tertiary cancer institution, receives many enquiries regarding use and safety of CAM with conventional cancer therapies (chemotherapy, radiotherapy...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brooks SL,Rowan G,Michael M

更新日期：2018-10-01 00:00:00

abstract：AIM:A proportion of locally advanced rectal cancer patients who receive neoadjuvant chemoradiotherapy (NACRT) are still unresectable. This study was undertaken to assess the outcomes of giving additional chemotherapy to rectal cancer patients with unresectable disease after NACRT. METHODS:Patients with poor response t...

journal_title：Asia-Pacific journal of clinical oncology

authors： Engineer R,Ostwal V,Arya S,Gupta P,Chopra S,Patil P,Jatal S,Saklani A

更新日期：2017-08-01 00:00:00

abstract：AIM:In colorectal cancer (CRC), adjuvant therapy is offered on the basis of stage and attempts to identify factors to better target treatment have not been successful. Recent work suggested that mismatch repair deficient CRCs may not benefit from 5FU adjuvant chemotherapy but studies remain conflicting. We aimed to det...

journal_title：Asia-Pacific journal of clinical oncology

authors： Thomas ML,Hewett PJ,Ruszkiewicz AR,Moore JW

更新日期：2015-12-01 00:00:00

abstract：AIM:The objective of this economic evaluation, which was based on patients from two randomized controlled clinical trials (NO16966 and NO16967), was to compare direct medical costs to the Australian health-care system of capecitabine plus oxaliplatin (XELOX) and bolus and/or infusional 5-fluorouracil (5-FU) plus folini...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tran G,Hack SP,Kerr A,Stokes L,Gibbs P,Price T,Todd C

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To review the outcomes of metastatic melanoma patients treated with infliximab for severe steroid-refractory colitis secondary to ipilimumab therapy. BACKGROUND:Immune-related colitis is a known potential adverse effect of ipilimumab, that causes significant morbidity and extended hospital stays. There are l...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hillock NT,Heard S,Kichenadasse G,Hill CL,Andrews J

更新日期：2017-10-01 00:00:00

abstract：AIM:Gastric cancer patients are normally treated with oral fluoropyrimidine and cisplatin or oxaliplatin; however, treating patients who also have a gastrointestinal obstruction is often difficult because of their poor oral intake. Instead, a modified (m)FOLFOX-6 regimen is administered, even to patients with gastroint...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yukami H,Terazawa T,Goto M,Aoki M,Asaishi K,Yamaguchi T,Kuwakado S,Kii T,Higuchi K

更新日期：2019-10-01 00:00:00

abstract：AIM:Multidisciplinary care is advocated as best practice in cancer care. Relatively little is documented about multidisciplinary team (MDT) meeting functioning, decision making and the use of evidence to support decision making in Australia. This descriptive study aimed to examine team functioning, the role of team mee...

journal_title：Asia-Pacific journal of clinical oncology

authors： Rankin NM,Lai M,Miller D,Beale P,Spigelman A,Prest G,Turley K,Simes J

更新日期：2018-02-01 00:00:00

abstract：AIM:Integration of clinical genetics into oncology is variable. Sarcomas have a strong genetic component, with up to 1/30 patients carrying germline TP53 mutations. This study aimed to define genetic risk awareness among sarcoma physicians. Outcomes were attitudes toward genetic testing, level of cancer risk and awaren...

journal_title：Asia-Pacific journal of clinical oncology

authors： McBride KA,Schlub TE,Ballinger ML,Thomas DM,Tattersall MH

更新日期：2016-06-01 00:00:00

abstract：AIM:To carry out a nationwide study of KRAS testing in metastatic colorectal cancer as reported by nine major molecular pathology service providers in Australia, including mutation frequencies and turnaround times that might impact on patient care. METHODS:Participating laboratories contributed information on KRAS mut...

journal_title：Asia-Pacific journal of clinical oncology

authors： Scott RJ,Fox SB,Desai J,Grieu F,Amanuel B,Garrett K,Harraway J,Cheetham G,Pattle N,Haddad A,Byron K,Rudzki B,Waring P,Iacopetta B

更新日期：2014-09-01 00:00:00

abstract：AIM:To explore the incidence of subclinical cardiotoxicity in women treated with adjuvant trastuzumab in the early breast cancer setting using cardiac magnetic resonance imaging (cMRI). METHODS:The cardiac function and myocardial tissue characteristics of 25 women who had completed adjuvant trastuzumab therapy greater...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lawley C,Wainwright C,Segelov E,Lynch J,Beith J,McCrohon J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Primary squamous cell carcinoma of the breast (PSCCB) is a rare clinical classification of breast tumors. Little is known about its clinicopathological features, prognosis and potential therapeutic strategies. The purpose of this study is to evaluate the effect of postoperative radiotherapy (PORT) on patient...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wang X,Zhang L,Luo J,Jin K,Yang Z,Meng J,Zhang X,Zhang Z,Shao Z,Guo X,Chen X,Yu X

更新日期：2020-10-20 00:00:00

abstract：AIM:Vascular endothelial growth facto receptor-tyrosine kinase inhibitors (VEGFR-TKIs) are widely used for metastatic renal cell carcinoma (mRCC). The aim of this study was to investigate the association between the response to VEGFR-TKIs and hyperlipidemia and hypothyroidism. METHODS:Clinical data on 155 patients wit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Song Y,Du C,Zhang W,Sun Y,Yang L,Cui C,Chi Y,Shou J,Zhou A,Wang J,Sun Y

更新日期：2016-06-01 00:00:00

abstract：AIMS:Cyclophosphamide was widely used as a single agent prior to the advent of platinum-based regimens for epithelial ovarian cancer, and, in combination with platinum, prior to the adoption of platinum and paclitaxel as standard first-line therapy. As cyclophosphamide currently has no defined role in ovarian cancer we...

journal_title：Asia-Pacific journal of clinical oncology

authors： Handolias D,Quinn M,Foo S,Mileshkin L,Grant P,Dutu G,Rischin D

更新日期：2016-03-01 00:00:00

abstract：AIM:We investigated prognostic significance of methylation status of MASPIN gene and its protein expression in normal subjects, cholelithiasis and gallbladder cancer (GBC) patients. METHODS:MASPIN protein expression and its promoter methylation in gallbladder tissue of cholelithiasis (n = 36), GBC (n = 46) and control...

journal_title：Asia-Pacific journal of clinical oncology

authors： Baghel K,Kazmi HR,Chandra A,Raj S,Srivastava RN

更新日期：2019-10-01 00:00:00

abstract：AIM:Elevated neutrophil-to-lymphocyte ratio (NLR) has been demonstrated to be a poor prognostic factor in multiple types of malignancies, whereas the effect of NLR on the prognosis of epidermal growth factor receptor (EGFR)-mutated advanced non-small-cell lung cancer (NSCLC) patients treated with first-line EGFR tyrosi...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lin GN,Peng JW,Liu PP,Liu DY,Xiao JJ,Chen XQ

更新日期：2017-10-01 00:00:00

abstract：AIM:This multicenter, observational study aimed to investigate the survival benefit of eribulin as well as that of taxane-based regimens in Japanese patients with metastatic breast cancer (MBC) in a real-world setting. METHODS:This study enrolled women with MBC who received eribulin or taxane-based regimens with or wi...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kikuchi Y,Uchida Y,Shirakawa K,Kanauchi H,Niwa T,Nishioka K,Tada K,Hashimoto M,Yasuda H,Sugiura R,Kawabata H,Seto Y,Ogawa T

更新日期：2018-10-01 00:00:00

abstract：AIMS:To determine the feasibility of stereotactic body radiotherapy (SBRT) in patients with pelvic sidewall recurrence of uterine cervical cancer after radical hysterectomy or definitive radiotherapy. METHODS:We retrospectively reviewed 23 patients with locally recurrent uterine cervical cancer limited to the pelvic s...

journal_title：Asia-Pacific journal of clinical oncology

authors： Seo Y,Kim MS,Yoo HJ,Jang WI,Rhu SY,Choi SC,Kim MH,Kim BJ,Lee DH,Cho CK

更新日期：2016-06-01 00:00:00

abstract：AIM:Autoimmune hemolytic anemia (AIHA) is frequently associated with B-cell lymphoproliferative disorders, and patients rarely develop overt clinical manifestations of AIHA. AIHA is rare in patients with multiple myeloma (MM). We conducted a prospective study to detect the presence of AIHA in MM patients and its impact...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kashyap R,Singh A,Kumar P

更新日期：2016-06-01 00:00:00

abstract：AIMS:In this study, we intended to analyze the clinical significance of CD4+ FoxP3+ Tregs in gastric cancer patients and investigate the relationship between the proportion of CD4+ FoxP3+ Tregs in the peripheral blood and the expression of FoxM1 and Ki-67 in gastric cancer tissues. METHODS:Flow cytometry was used to m...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ma K,Li X,Lv J,Liu Z,Zhang L,Cong H,Wang H,Shen F,Yue L

更新日期：2020-01-19 00:00:00

abstract：AIM:Carboplatin dosing depends on accurate glomerular filtration rate (GFR) estimation. There is a lack of clinical agreement about carboplatin dosing when the GFR measurement is very high (>110 mL/min). METHODS:A retrospective audit of pre-chemotherapy 99m technetium (Tc) diethylenetriamene pentaacetate (DTPA) radion...

journal_title：Asia-Pacific journal of clinical oncology

authors： Roy AC,Jones DN,Slavotinek JP,Kichenadasse G,Karapetis C,Lam E,Bishnoi S,Koczwara B

更新日期：2011-09-01 00:00:00

abstract：AIM:Long noncoding RNAs play a key role in the development and progression of various human cancers. Recently, LINC00852 has been reported to be associated with spinal metastasis lung adenocarcinoma. However, the role and potential mechanisms of LINC00852 in prostate cancer cells remain largely unknown. METHODS:LINC00...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yi S,Li G,Sun B

更新日期：2020-10-30 00:00:00

abstract：AIMS:Esophageal cancer (EC) is one of the most prevalent and deadly cancers worldwide. Along with nutrition, smoking and alcohol consumption, human papillomavirus (HPV) infection is one of the major risk factors, which is modulated by host immune response. This study is aimed at elucidating how HPV modifies host immune...

journal_title：Asia-Pacific journal of clinical oncology

authors： Feng B,Awuti I,Deng Y,Li D,Niyazi M,Aniwar J,Sheyhidin I,Lu G,Li G,Zhang L

更新日期：2014-03-01 00:00:00

abstract：:First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used as first-line therapy in patients with non-small cell lung cancer (NSCLC) harboring a sensitizing mutation in the EGFR gene. Unfortunately, resistance to these therapies often occurs within 10 months of commencing treat...

journal_title：Asia-Pacific journal of clinical oncology

authors： John T,Bowden JJ,Clarke S,Fox SB,Garrett K,Horwood K,Karapetis CS

更新日期：2017-08-01 00:00:00

abstract：AIM:This systematic review and meta-analysis was performed to assess the efficacy and side effects between single-agent and doublet chemotherapy in first-line treatment of advanced non-small cell lung cancer with performance status 2 (PS2). METHODS:We searched for randomized controlled trials in online electronic data...

journal_title：Asia-Pacific journal of clinical oncology

authors： Luo L,Hu Q,Jiang JX,Yang X,Dinglin XX,Lin X,Yao HR

更新日期：2015-09-01 00:00:00

abstract：AIM:Retroperitoneal sarcomas (RPSs) are large, rare tumors. The role of core biopsy for retroperitoneal masses identified by preoperative imaging is unclear and we report the safety and accuracy of core biopsies at a specialized sarcoma unit in Sydney, Australia. METHODS:A retrospective analysis of a prospectively col...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hwang SY,Warrier S,Thompson S,Davidson T,Yang JL,Crowe P

更新日期：2016-03-01 00:00:00

abstract：AIM:While first-line palliative chemotherapy (CT1) improves survival and quality of life in advanced biliary cancer (ABC), there is no randomized evidence to support second-line chemotherapy (CT2) in ABC. We aim to explore to role of CT2 in ABC. METHODS:We performed a retrospective review of all patients who received ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brungs D,Aghmesheh M,Sjoquist K,Goldstein D

更新日期：2017-10-01 00:00:00

abstract：:Health literacy refers to one's ability to obtain, process and understand health information and services to enable sound health decision-making. This is an area of increasing importance due to the complexity of the health system, especially in the cancer setting. A certain level of health literacy is required for pat...

journal_title：Asia-Pacific journal of clinical oncology

authors： Koay K,Schofield P,Jefford M

更新日期：2012-03-01 00:00:00

abstract：AIM:To describe the development of the content and pilot testing of a radiation therapist-led educational intervention for breast cancer patients about to commence radiotherapy. Pilot testing consisted of testing the intervention for appropriateness, feasibility and acceptance. METHODS:A tailored intervention consisti...

journal_title：Asia-Pacific journal of clinical oncology

authors： Halkett GK,Schofield P,O'Connor M,York D,Jefford M,Jiwa M,Spry N,Taylor M,Aranda S

更新日期：2012-09-01 00:00:00