Safety and accuracy of core biopsy in retroperitoneal sarcomas.

abstract：AIM:Integration of clinical genetics into oncology is variable. Sarcomas have a strong genetic component, with up to 1/30 patients carrying germline TP53 mutations. This study aimed to define genetic risk awareness among sarcoma physicians. Outcomes were attitudes toward genetic testing, level of cancer risk and awaren...

journal_title：Asia-Pacific journal of clinical oncology

authors： McBride KA,Schlub TE,Ballinger ML,Thomas DM,Tattersall MH

更新日期：2016-06-01 00:00:00

abstract：AIM:To carry out a nationwide study of KRAS testing in metastatic colorectal cancer as reported by nine major molecular pathology service providers in Australia, including mutation frequencies and turnaround times that might impact on patient care. METHODS:Participating laboratories contributed information on KRAS mut...

journal_title：Asia-Pacific journal of clinical oncology

authors： Scott RJ,Fox SB,Desai J,Grieu F,Amanuel B,Garrett K,Harraway J,Cheetham G,Pattle N,Haddad A,Byron K,Rudzki B,Waring P,Iacopetta B

更新日期：2014-09-01 00:00:00

abstract：AIM:Advanced esophagogastric carcinoma has a poor prognosis. Palliative chemotherapy provides a survival advantage and improved quality of life. Epirubicin, cisplatin and continuous infusional 5-fluorouracil (5-FU) (ECF) is a well-established chemotherapy regimen but a continuous chemotherapy infusion is not always fea...

journal_title：Asia-Pacific journal of clinical oncology

authors： Karapetis CS,Cheong KA,Yip D,Strickland AH,Steer C,Marx G,Yip S,Chrystal K,Harper PG

更新日期：2010-12-01 00:00:00

abstract：AIM:Carboplatin dosing depends on accurate glomerular filtration rate (GFR) estimation. There is a lack of clinical agreement about carboplatin dosing when the GFR measurement is very high (>110 mL/min). METHODS:A retrospective audit of pre-chemotherapy 99m technetium (Tc) diethylenetriamene pentaacetate (DTPA) radion...

journal_title：Asia-Pacific journal of clinical oncology

authors： Roy AC,Jones DN,Slavotinek JP,Kichenadasse G,Karapetis C,Lam E,Bishnoi S,Koczwara B

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Anti-HER2 therapy-related cardiotoxicity is well described in the context of clinical trials, particularly in the setting of early stage disease, but there is more limited data in advanced breast cancer and in the real world setting. MATERIAL AND METHODS:A prospectively-maintained registry database with 312...

journal_title：Asia-Pacific journal of clinical oncology

authors： Conduit C,de Boer RH,Lok S,Gibbs P,Malik L,Loh Z,Yeo B,Greenberg S,Devitt B,Lombard J,Nottage M,Collins I,Torres J,Nolan M,Nott L

更新日期：2020-12-01 00:00:00

abstract：AIMS:In this study, we intended to analyze the clinical significance of CD4+ FoxP3+ Tregs in gastric cancer patients and investigate the relationship between the proportion of CD4+ FoxP3+ Tregs in the peripheral blood and the expression of FoxM1 and Ki-67 in gastric cancer tissues. METHODS:Flow cytometry was used to m...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ma K,Li X,Lv J,Liu Z,Zhang L,Cong H,Wang H,Shen F,Yue L

更新日期：2020-01-19 00:00:00

abstract：AIM:Vascular endothelial growth facto receptor-tyrosine kinase inhibitors (VEGFR-TKIs) are widely used for metastatic renal cell carcinoma (mRCC). The aim of this study was to investigate the association between the response to VEGFR-TKIs and hyperlipidemia and hypothyroidism. METHODS:Clinical data on 155 patients wit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Song Y,Du C,Zhang W,Sun Y,Yang L,Cui C,Chi Y,Shou J,Zhou A,Wang J,Sun Y

更新日期：2016-06-01 00:00:00

abstract：AIMS:Esophageal cancer (EC) is one of the most prevalent and deadly cancers worldwide. Along with nutrition, smoking and alcohol consumption, human papillomavirus (HPV) infection is one of the major risk factors, which is modulated by host immune response. This study is aimed at elucidating how HPV modifies host immune...

journal_title：Asia-Pacific journal of clinical oncology

authors： Feng B,Awuti I,Deng Y,Li D,Niyazi M,Aniwar J,Sheyhidin I,Lu G,Li G,Zhang L

更新日期：2014-03-01 00:00:00

abstract：AIM:A newly developed cervical cancer screening method - folate receptor-mediated epithelium staining utilizes methylene blue internalized by folate receptor-mediated endocytosis to stain cervical intra-epithelial neoplasia. We test the clinical feasibility of this method in this study. METHODS:A total of 14 344 women...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li D,Chen L,Wang H,Yang H,Dai Y,Yu C,Dong Y

更新日期：2017-02-01 00:00:00

abstract：AIM:The ACCElox registry was set up to assess therapeutic management of early-stage colon cancer with oxaliplatin/5-fluorouracil (5-FU)-based regimen and the duration of adjuvant chemotherapy in current clinical practice. METHODS:This prospective observational study was conducted between 2006 and 2008 in 19 countries ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Park YS,Ji J,Zalcberg JR,El-Serafi M,Buzaid A,Ghosn M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:MRI and PET/CT scans are the main supportive methods for nasopharyngeal cancer (NPC) for staging and planning. The aim of this study is to compare MRI and PET/CT scanning in terms of survival in patients with NPC who had MRI or PET/CT-simulated radiotherapy planning. METHODS:Pathological diagnosed nonkerati...

journal_title：Asia-Pacific journal of clinical oncology

authors： Gundog M,Basaran H,Dogan S,Abdulrezzak U

更新日期：2021-02-01 00:00:00

abstract：:Ipilimumab is a human anti-CTLA-4 monoclonal antibody recently approved for the treatment of advanced melanoma. Stimulation of T-cell activity unmasks antitumor activity, but can cause immune-related adverse events. Autoimmune hypophysitis is of particular importance because its presentation can be subtle but life thr...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tiu C,Pezaro C,Davis ID,Grossmann M,Parente P

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Azacitidine safety and efficacy were established in studies of mainly Caucasian patients. Differences in drug metabolism enzymes between Caucasian and East Asian populations prevent extrapolation of drug effects between these groups. This phase 2 study evaluated azacitidine safety, efficacy and pharmacokinet...

journal_title：Asia-Pacific journal of clinical oncology

authors： Du X,Lai YY,Xiao Z,Liu T,Hu Y,Sun A,Li X,Shen ZX,Jin J,Yu L,Laille E,Dong Q,Songer S,Beach CL

更新日期：2018-06-01 00:00:00

abstract：:Multidisciplinary oncology team meetings are crucial hubs for integrated, patient-centered diagnosis and treatment planning. Team meetings are designed to enact the best practice principles of multidisciplinary care. Yet surveys of clinicians and allied health providers who are members of multidisciplinary teams (MDTs...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lamprell K,Arnolda G,Delaney GP,Liauw W,Braithwaite J

更新日期：2019-08-01 00:00:00

abstract：AIM:To explore the incidence of subclinical cardiotoxicity in women treated with adjuvant trastuzumab in the early breast cancer setting using cardiac magnetic resonance imaging (cMRI). METHODS:The cardiac function and myocardial tissue characteristics of 25 women who had completed adjuvant trastuzumab therapy greater...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lawley C,Wainwright C,Segelov E,Lynch J,Beith J,McCrohon J

更新日期：2012-03-01 00:00:00

abstract：AIMS:Currently, the only standard systemic treatment for advanced hepatocellular carcinoma is sorafenib monotherapy. The study was conducted to assess the efficacy and safety of the novel combination of sorafenib and gemcitabine in the treatment of advanced hepatocellular carcinoma. METHODS:Between March 2008 and Octo...

journal_title：Asia-Pacific journal of clinical oncology

authors： Srimuninnimit V,Sriuranpong V,Suwanvecho S

更新日期：2014-09-01 00:00:00

abstract：AIM:To describe the overall survival, progression-free survival, response rate and toxicity of pegylated liposomal doxorubicin (PLD) in recurrent ovarian cancer. METHODS:A retrospective study of 45 patients with recurrent or progressive ovarian cancer was conducted at the Westmead Cancer Care Centre. Patients received...

journal_title：Asia-Pacific journal of clinical oncology

authors： Dear RF,Gao B,Harnett P

更新日期：2010-03-01 00:00:00

abstract：AIM:Metadherin (MTDH) is a potential oncogene in tumor development and is highly expressed in various types of human cancers. However, there has been no report on the role of MTDH in bladder cancer. Our aim was to investigate the expression pattern of MTDH in bladder tissue at different clinic pathological stages and e...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou J,Li J,Wang Z,Yin C,Zhang W

更新日期：2012-09-01 00:00:00

abstract：AIMS:The Australian Institute of Health and Welfare (AIHW) is a major national agency established by the Australian government to provide information and statistics on Australia's health and welfare. The AIHW and the Australasian Association of Cancer Registries collaborate every year to provide updated information on ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Australian Institute of Health and Welfare.

更新日期：2013-09-01 00:00:00

abstract：AIMS:Cyclophosphamide was widely used as a single agent prior to the advent of platinum-based regimens for epithelial ovarian cancer, and, in combination with platinum, prior to the adoption of platinum and paclitaxel as standard first-line therapy. As cyclophosphamide currently has no defined role in ovarian cancer we...

journal_title：Asia-Pacific journal of clinical oncology

authors： Handolias D,Quinn M,Foo S,Mileshkin L,Grant P,Dutu G,Rischin D

更新日期：2016-03-01 00:00:00

abstract：:Cancer, its therapy, and related adverse effects have been associated with reduced work performance, including absenteeism (i.e. absence from scheduled work due to health problems) and presenteeism (i.e. impaired on-the-job performance due to health problems) among cancer survivors. This review aimed to compare the wo...

journal_title：Asia-Pacific journal of clinical oncology

authors： Soejima T,Kamibeppu K

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Docetaxel is an effective therapy for metastatic castration-resistant prostate cancer (mCRPC); however, many patients experience febrile neutropenia (FN) and cease treatment early due to toxicity. It is not known whether lower dose (LD) q3-weekly docetaxel impacts toxicity or efficacy. METHODS:Multicenter r...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hamid AA,Willson K,Vincent AD,Tamjid B,Lee M,Bergin A,Gan C,Campbell A,Stewart J,Pezaro C,Tran B,Weickhardt AJ

更新日期：2018-10-01 00:00:00

abstract：AIM:The objective of this economic evaluation, which was based on patients from two randomized controlled clinical trials (NO16966 and NO16967), was to compare direct medical costs to the Australian health-care system of capecitabine plus oxaliplatin (XELOX) and bolus and/or infusional 5-fluorouracil (5-FU) plus folini...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tran G,Hack SP,Kerr A,Stokes L,Gibbs P,Price T,Todd C

更新日期：2013-09-01 00:00:00

abstract：:First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used as first-line therapy in patients with non-small cell lung cancer (NSCLC) harboring a sensitizing mutation in the EGFR gene. Unfortunately, resistance to these therapies often occurs within 10 months of commencing treat...

journal_title：Asia-Pacific journal of clinical oncology

authors： John T,Bowden JJ,Clarke S,Fox SB,Garrett K,Horwood K,Karapetis CS

更新日期：2017-08-01 00:00:00

abstract：AIM:Mucositis is a major complication of irradiation in head and neck tumors, the addition of chemotherapy to irradiation may enhance this dose-limiting problem. Licorice is a strong demulcent that had been effectively used in treatment of peptic ulcer. The main purpose of this study was to compare the therapeutic safe...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ghalayani P,Emami H,Pakravan F,Nasr Isfahani M

更新日期：2017-04-01 00:00:00

abstract：AIM:Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. METHOD:All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single ...

journal_title：Asia-Pacific journal of clinical oncology

authors： How SH,Ng TH,Kuan YC,Jamalludin AR,Fauzi AR

更新日期：2015-09-01 00:00:00

abstract：AIM:For several decades urinary arylsulfatase (ARS) activity has been reported to be elevated in many cancers. It has been shown that urinary ARS activity may serve as a marker of tumor progression and therapy surveillance. This study was designed to evaluate the clinical application of detection of urinary ARS activit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Niu R,Jing H,Chen Z,Xu J,Dai J,Yan Z

更新日期：2012-12-01 00:00:00

abstract：AIM:Self-expandable metallic stents (SEMS) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. METHODS:A review of records of 85 patients with unresectable ga...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cha BH,Lee SH,Kim JE,Yoo JY,Park YS,Kim JW,Jeong SH,Kim N,Lee DH,Hwang JH

更新日期：2013-06-01 00:00:00

abstract：AIM:To examine the treatment practices for cancer pain relief and adverse event management, and the factors related to patient outcomes in the participating countries/regions. METHODS:The study was a cross-sectional survey conducted between September and December 2013 in 10 countries/regions across Asia. Adult patient...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ho KY,Ahn JS,Calimag MM,Chao TC,Kim YC,Moon H,Tho LM,Xia ZJ,You D

更新日期：2018-06-01 00:00:00

abstract：AIMS:Extracorporeal irradiation and re-implantation (ECI) has been used as limb salvage surgery for musculoskeletal oncology patients. Biological reconstruction, no risk of disease transmission and immunological reaction, ready availability and preservation of bone stock are the major advantage of this surgical techniq...

journal_title：Asia-Pacific journal of clinical oncology

authors： Arpornchayanon O,Leerapun T,Pruksakorn D,Panichkul P

更新日期：2013-09-01 00:00:00