Very high GFR in cancer patients undergoing chemotherapy: prevalence, carboplatin dosing patterns and chemotherapy toxicity.

abstract：AIM:To evaluate the attitudes of patients with different cancers towards research biopsies outside a clinical trial. METHODS:Patients with metastatic cancer completed a questionnaire that assessed patients' willingness to consider research biopsies. Research biopsies were divided into two groups: biopsies performed as...

journal_title：Asia-Pacific journal of clinical oncology

authors： Robinson DH,Churilov L,Lin NU,Lim E,Seah D

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Azacitidine safety and efficacy were established in studies of mainly Caucasian patients. Differences in drug metabolism enzymes between Caucasian and East Asian populations prevent extrapolation of drug effects between these groups. This phase 2 study evaluated azacitidine safety, efficacy and pharmacokinet...

journal_title：Asia-Pacific journal of clinical oncology

authors： Du X,Lai YY,Xiao Z,Liu T,Hu Y,Sun A,Li X,Shen ZX,Jin J,Yu L,Laille E,Dong Q,Songer S,Beach CL

更新日期：2018-06-01 00:00:00

abstract：AIM:To investigate the association between plasma visfatin levels and risk of early and advanced colorectal cancer (CRC). METHODS:In total, 358 CRC patients and 286 controls were enrolled. According to the T factor of the TNM system. cancer patients were divided into two subgroups: early and advanced cancer. Levels of...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen M,Wang Y,Li Y,Zhao L,Ye S,Wang S,Yu C,Xie H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Definitive chemoradiotherapy (CRT) is the standard treatment for locally advanced head and neck cancer (HNC). However, for very elderly patients, the comparison of benefit/risk between definitive radiotherapy (RT) with and without systemic chemotherapy was equivocal. PATIENTS AND METHODS:The study was a sin...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lai KM,Lin JT,Lu HJ,Liang CC,Chen MK

更新日期：2018-06-01 00:00:00

abstract：AIM:Cabazitaxel is a next generation taxane that has been shown to improve overall survival in patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease progressed during or after docetaxel-based therapy. A worldwide early access program (EAP) study was established to provide access to cabazit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Parente P,Ng S,Parnis F,Guminski A,Gurney H

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:The goal of this study was to determine the relationships among type 2 diabetes mellitus (DM), specific cancer histological types and mortality in hospitalized women. METHODS:Patients over 19 years of age were included if the indication for hospital admission was a diagnosis of type 2 DM or a malignancy. ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen JY,Chiou WK,Chou WY,Lin JD

更新日期：2016-03-01 00:00:00

abstract：AIM:For early-stage breast cancer, four cycles of docetaxel and cyclophosphamide (TC) was proven superior to doxorubicin plus cyclophosphamide in the US Oncology 9375 trial. Given primary prophylactic antibiotics, 5% febrile neutropenia was recorded in a population comprising 75.5% Caucasians. Smaller trials and retros...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chow LWC,Biganzoli L,Leo AD,Kuroi K,Han HS,Patel J,Huang CS,Lu YS,Zhu L,Chow CYC,Loo WTY,Glück S,Toi M

更新日期：2017-12-01 00:00:00

abstract：AIM:To describe the overall survival, progression-free survival, response rate and toxicity of pegylated liposomal doxorubicin (PLD) in recurrent ovarian cancer. METHODS:A retrospective study of 45 patients with recurrent or progressive ovarian cancer was conducted at the Westmead Cancer Care Centre. Patients received...

journal_title：Asia-Pacific journal of clinical oncology

authors： Dear RF,Gao B,Harnett P

更新日期：2010-03-01 00:00:00

abstract：:Resistance to endocrine therapy is a significant therapeutic challenge in the treatment of women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer. Cyclin-dependent kinase (CDK)4/6 inhibitors in combination with endocrine therapy have been shown to i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Boyle F,Beith J,Burslem K,de Boer R,Hui R,Lim E,McCarthy N,Redfern A,Woodward N

更新日期：2018-10-01 00:00:00

abstract：:Health literacy refers to one's ability to obtain, process and understand health information and services to enable sound health decision-making. This is an area of increasing importance due to the complexity of the health system, especially in the cancer setting. A certain level of health literacy is required for pat...

journal_title：Asia-Pacific journal of clinical oncology

authors： Koay K,Schofield P,Jefford M

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Clinical trials investigating the effects of addition of oxaliplatin to neoadjuvant radiochemotherapy in locally advanced rectal cancers (LARCs) have brought controversial results for pathologic complete response as an endpoint. This randomized clinical trial investigated downstaging as a short-term surrogat...

journal_title：Asia-Pacific journal of clinical oncology

authors： Haddad P,Miraie M,Farhan F,Fazeli MS,Alikhassi A,Maddah-Safaei A,Aghili M,Kalaghchi B,Babaei M

更新日期：2017-12-01 00:00:00

abstract：:The precise cell types that give rise to tumors and mechanisms that underpin tumor heterogeneity are poorly understood. There is increasing evidence to suggest that diverse solid tumors are hierarchically organized and may be sustained by a distinct subpopulation of cancer stem cells (CSCs). The CSC hypothesis provide...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lindeman GJ,Visvader JE

更新日期：2010-06-01 00:00:00

abstract：AIM:Survival rates for patients with cancer who live in rural and regional areas are worse than in metropolitan areas. This may be due to geographical isolation, delayed diagnosis, inadequate transport, lower socioeconomic status and workforce shortages. We conducted a qualitative study of rural patients, carers and he...

journal_title：Asia-Pacific journal of clinical oncology

authors： Grimison P,Phillips F,Butow P,White K,Yip D,Sardelic F,Underhill C,Tse R,Simes R,Turley K,Raymond C,Goldstein D

更新日期：2013-09-01 00:00:00

abstract：AIM:Autoimmune hemolytic anemia (AIHA) is frequently associated with B-cell lymphoproliferative disorders, and patients rarely develop overt clinical manifestations of AIHA. AIHA is rare in patients with multiple myeloma (MM). We conducted a prospective study to detect the presence of AIHA in MM patients and its impact...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kashyap R,Singh A,Kumar P

更新日期：2016-06-01 00:00:00

abstract：:Posterior reversible encephalopathy syndrome (PRES) is a neuro-radiological syndrome characterized by seizures, altered level of consciousness and visual disturbance. PRES is associated with hyperintense lesions on magnetic resonance imaging (MRI) most commonly seen in the posterior regions. In most cases symptoms and...

journal_title：Asia-Pacific journal of clinical oncology

authors： Femia G,Hardy TA,Spies JM,Horvath LG

更新日期：2012-06-01 00:00:00

abstract：AIM:The ACCElox registry was set up to assess therapeutic management of early-stage colon cancer with oxaliplatin/5-fluorouracil (5-FU)-based regimen and the duration of adjuvant chemotherapy in current clinical practice. METHODS:This prospective observational study was conducted between 2006 and 2008 in 19 countries ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Park YS,Ji J,Zalcberg JR,El-Serafi M,Buzaid A,Ghosn M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:An elevated preoperative aspartate aminotransferase-to-lymphocyte ratio index (ALRI) may predict poor survival in various cancers. However, the prognostic value of aminotransferase-to-lymphocyte ratio index (ALRI) in patients with hepatocellular carcinoma (HCC) remains to be determined. MATERIALS AND METHOD...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen Y,He C,Wen T,Yan L,Yang J

更新日期：2020-10-30 00:00:00

abstract：AIM:To examine the treatment practices for cancer pain relief and adverse event management, and the factors related to patient outcomes in the participating countries/regions. METHODS:The study was a cross-sectional survey conducted between September and December 2013 in 10 countries/regions across Asia. Adult patient...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ho KY,Ahn JS,Calimag MM,Chao TC,Kim YC,Moon H,Tho LM,Xia ZJ,You D

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:Ki-67 proliferation index (Ki-67 index) is used to quantify cell proliferation during histopathological assessment of various tumors including glioblastoma (GB). AIM:We aimed to assess correlation between Ki-67 index and overall survival in patients with GB and determine a cut-point for Ki-67 index that p...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wong E,Nahar N,Hau E,Varikatt W,Gebski V,Ng T,Jayamohan J,Sundaresan P

更新日期：2019-02-01 00:00:00

abstract：AIM:Clinical and pharmacokinetic effects of azacitidine in higher-risk myelodysplastic syndromes were established in mainly Caucasian populations. Because of inter-ethnic genotype variability of drug-metabolizing enzymes, it is important to evaluate azacitidine in populations expected to use the drug. METHODS:In this ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chou WC,Yeh SP,Hsiao LT,Lin SF,Chen YC,Chen TY,Laille E,Galettis A,Dong Q,Songer S,Beach CL

更新日期：2017-10-01 00:00:00

abstract：AIM:The open-label, nonrandomized, phase II APEC study enrolled 167 patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) to investigate the safety and efficacy of first-line, every-2-weeks cetuximab plus investigator's choice of FOLFIRI or FOLFOX in this patient population. METHODS:A subgroup analysis ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Price T,Shen L,Ma B,Esser R,Chen W,Gibbs P,Lim R,Cheng AL

更新日期：2019-08-01 00:00:00

abstract：AIM:Colorectal cancer (CRC) is one of the most common malignancies worldwide and adjuvant chemotherapy is proven to improve survival in patients with Dukes' C CRC. The purpose of this study was to analyze factors influencing referral to medical oncology in patients with Dukes' C colonic cancer in our institutions. MET...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu CT,Stephens JH,Rieger NA

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The comprehensive genetic alterations underlying the pathogenesis of Sézary syndrome (SS) remains largely unknown. Previous studies showed that alterations of tumor necrosis factor-α-induced protein 3 gene (TNFAIP3; A20) are frequent in SS. In this study, we characterized the mutation and polymorphisms of A2...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou L,Zheng H,Huang X,Zhu L,Wu S,Zeng C,Yang L,Chen S,Luo G,Du X,Li Y

更新日期：2018-04-01 00:00:00

abstract：AIMS:In this study, we intended to analyze the clinical significance of CD4+ FoxP3+ Tregs in gastric cancer patients and investigate the relationship between the proportion of CD4+ FoxP3+ Tregs in the peripheral blood and the expression of FoxM1 and Ki-67 in gastric cancer tissues. METHODS:Flow cytometry was used to m...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ma K,Li X,Lv J,Liu Z,Zhang L,Cong H,Wang H,Shen F,Yue L

更新日期：2020-01-19 00:00:00

abstract：AIMS:Extracorporeal irradiation and re-implantation (ECI) has been used as limb salvage surgery for musculoskeletal oncology patients. Biological reconstruction, no risk of disease transmission and immunological reaction, ready availability and preservation of bone stock are the major advantage of this surgical techniq...

journal_title：Asia-Pacific journal of clinical oncology

authors： Arpornchayanon O,Leerapun T,Pruksakorn D,Panichkul P

更新日期：2013-09-01 00:00:00

abstract：AIM:A newly developed cervical cancer screening method - folate receptor-mediated epithelium staining utilizes methylene blue internalized by folate receptor-mediated endocytosis to stain cervical intra-epithelial neoplasia. We test the clinical feasibility of this method in this study. METHODS:A total of 14 344 women...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li D,Chen L,Wang H,Yang H,Dai Y,Yu C,Dong Y

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:MRI and PET/CT scans are the main supportive methods for nasopharyngeal cancer (NPC) for staging and planning. The aim of this study is to compare MRI and PET/CT scanning in terms of survival in patients with NPC who had MRI or PET/CT-simulated radiotherapy planning. METHODS:Pathological diagnosed nonkerati...

journal_title：Asia-Pacific journal of clinical oncology

authors： Gundog M,Basaran H,Dogan S,Abdulrezzak U

更新日期：2021-02-01 00:00:00

abstract：AIM:Gastric cancer patients are normally treated with oral fluoropyrimidine and cisplatin or oxaliplatin; however, treating patients who also have a gastrointestinal obstruction is often difficult because of their poor oral intake. Instead, a modified (m)FOLFOX-6 regimen is administered, even to patients with gastroint...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yukami H,Terazawa T,Goto M,Aoki M,Asaishi K,Yamaguchi T,Kuwakado S,Kii T,Higuchi K

更新日期：2019-10-01 00:00:00

abstract：AIM:To evaluate tumor markers as prognostic factors in patients with metastatic or recurrent gastric cancer receiving first-line chemotherapy. METHODS:Between January 2000 and December 2008, 1178 patients with metastatic or recurrent gastric cancer were assayed for expression of three serum tumor markers, CA 19-9, CA ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jo JC,Ryu MH,Koo DH,Ryoo BY,Kim HJ,Kim TW,Choi KD,Lee GH,Jung HY,Yook JH,Oh ST,Kim BS,Kim JH,Kang YK

更新日期：2013-12-01 00:00:00

abstract：AIM:Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. METHOD:All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single ...

journal_title：Asia-Pacific journal of clinical oncology

authors： How SH,Ng TH,Kuan YC,Jamalludin AR,Fauzi AR

更新日期：2015-09-01 00:00:00