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Wearable-device-measured physical activity and future health risk.

Abstract：

:Use of wearable devices that monitor physical activity is projected to increase more than fivefold per half-decade1. We investigated how device-based physical activity energy expenditure (PAEE) and different intensity profiles were associated with all-cause mortality. We used a network harmonization approach to map dominant-wrist acceleration to PAEE in 96,476 UK Biobank participants (mean age 62 years, 56% female). We also calculated the fraction of PAEE accumulated from moderate-to-vigorous-intensity physical activity (MVPA). Over the median 3.1-year follow-up period (302,526 person-years), 732 deaths were recorded. Higher PAEE was associated with a lower hazard of all-cause mortality for a constant fraction of MVPA (for example, 21% (95% confidence interval 4-35%) lower hazard for 20 versus 15 kJ kg-1 d-1 PAEE with 10% from MVPA). Similarly, a higher MVPA fraction was associated with a lower hazard when PAEE remained constant (for example, 30% (8-47%) lower hazard when 20% versus 10% of a fixed 15 kJ kg-1 d-1 PAEE volume was from MVPA). Our results show that higher volumes of PAEE are associated with reduced mortality rates, and achieving the same volume through higher-intensity activity is associated with greater reductions than through lower-intensity activity. The linkage of device-measured activity to energy expenditure creates a framework for using wearables for personalized prevention.

journal_name

Nat Med

journal_title

Nature medicine

authors

Strain T,Wijndaele K,Dempsey PC,Sharp SJ,Pearce M,Jeon J,Lindsay T,Wareham N,Brage S

doi

10.1038/s41591-020-1012-3

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

1385-1391

issue

9

eissn

1078-8956

issn

1546-170X

pii

10.1038/s41591-020-1012-3

journal_volume

26

pub_type

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