Multimodal neuroimaging in anorexia nervosa.

abstract：:The chronic constriction injury (CCI) of the sciatic nerve is a nerve injury-based model of neuropathic pain (NP). Comorbidities of NP such as depression, anxiety, and cognitive deficits are associated with a functional reorganization of the medial prefrontal cortex (mPFC). Here, we have employed an adapted model of C...

journal_title：Journal of neuroscience research

authors： Medeiros P,de Freitas RL,Boccella S,Iannotta M,Belardo C,Mazzitelli M,Romano R,De Gregorio D,Coimbra NC,Palazzo E,Maione S

更新日期：2020-02-01 00:00:00

abstract：:Spinocerebellar ataxia type 17 (SCA17) is a type of autosomal dominant cerebellar ataxia (ADCA) characterized by variable manifestations, including cerebellar ataxia, dementia, and psychiatric symptoms. Since the identification of a CAG repeat expansion in the TATA-box binding protein (TBP) gene in a patient with atax...

journal_title：Journal of neuroscience research

authors： Cui Y,Yang S,Li XJ,Li S

更新日期：2017-08-01 00:00:00

abstract：:Grafting fetal ventral mesencephalon has been utilized to alleviate the symptoms of Parkinson's disease. One obstacle in using this approach is the limited outgrowth from the transplanted dopamine neurons. Thus, it is important to evaluate factors that promote outgrowth from fetal dopamine neurons. Proteoglycans (PGs)...

journal_title：Journal of neuroscience research

authors： Berglöf E,Plantman S,Johansson S,Strömberg I

更新日期：2008-01-01 00:00:00

abstract：:Studies using Aplysia californica have demonstrated that transcription after nerve injury occurs during a rapid, transient first phase and a delayed, prolonged second phase. Although the second phase is especially important for regeneration, the mRNAs produced during this phase have not been identified. We characteriz...

journal_title：Journal of neuroscience research

authors： Colby GP,Sung YJ,Ambron RT

更新日期：2005-11-15 00:00:00

abstract：:Dissociated neurons from the neural tube containing the trigeminal motor nucleus from early chick embryos were cultured on laminin or collagen-polyornithine substrates, with and without nerve growth factor (NGF). Control cultures were grown in similar conditions with cytochrome-C. It was found that neuronal survival w...

journal_title：Journal of neuroscience research

authors： Heaton MB

更新日期：1989-04-01 00:00:00

abstract：:Astroglial cells play an important role in maintaining neuronal function in the adult and in the developing nervous system. Ethanol exposure induces profound alterations in the astrogliogenesis process, affecting important cell functions, including intracellular protein trafficking. Because the actin cytoskeleton play...

journal_title：Journal of neuroscience research

authors： Guasch RM,Tomas M,Miñambres R,Valles S,Renau-Piqueras J,Guerri C

更新日期：2003-05-15 00:00:00

abstract：:Previous histochemical studies of iron in the brain demonstrated iron enrichment in oligodendrocytes, but the iron-enriched oligodendrocytes had a spatially restricted distribution that excluded major white matter tracts. In this study we used techniques designed to permeabilize tissue, combined with iron histochemist...

journal_title：Journal of neuroscience research

authors： LeVine SM,Macklin WB

更新日期：1990-08-01 00:00:00

abstract：:Amyloid plaques, found in characteristically large numbers in specific brain areas of Alzheimer's disease (AD) and Down's Syndrome (DS) patients, are composed of a 41-43 amino acid peptide, A4, derived from a transmembrane glycoprotein, amyloid precursor protein (APP). In transformed cells APP has been shown to be cle...

journal_title：Journal of neuroscience research

authors： Baskin F,Rosenberg RN,Greenberg BD

更新日期：1991-05-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) coactivates a number of transcription factors critical for mitochondrial biogenesis. Previously, we found that the expression of PGC-1alpha is governed by neuronal activity, but the signaling mechanism is poorly understood. The present st...

journal_title：Journal of neuroscience research

authors： Liang HL,Dhar SS,Wong-Riley MT

更新日期：2010-02-15 00:00:00

abstract：:Two fundamental questions about neuron cell culture were addressed. Can one serum-free medium that was developed for optimum growth of hippocampal neurons support the growth of neurons from other regions of the brain? Is the region specific state of differentiation maintained in culture? To answer these questions, we ...

journal_title：Journal of neuroscience research

authors： Brewer GJ

更新日期：1995-12-01 00:00:00

abstract：:The higher prevalence and risk for Alzheimer's disease in women relative to men has been partially attributed to the precipitous decline in gonadal hormone levels that occurs in women following the menopause. Although considerable attention has been focused on the consequence of estrogen loss, and thus estrogen's neur...

journal_title：Journal of neuroscience research

authors： Kaur P,Jodhka PK,Underwood WA,Bowles CA,de Fiebre NC,de Fiebre CM,Singh M

更新日期：2007-08-15 00:00:00

abstract：:Accumulating evidence indicates an immunosuppressive role for CD4(+)CD25(+) regulatory T cells (Tregs) in autoimmune diseases. Although an impaired Treg function in patients with relapsing-remitting multiple sclerosis (RR-MS) has been reported recently, no information is available so far about Treg function in the pro...

journal_title：Journal of neuroscience research

authors： Venken K,Hellings N,Hensen K,Rummens JL,Medaer R,D'hooghe MB,Dubois B,Raus J,Stinissen P

更新日期：2006-06-01 00:00:00

abstract：:Extracts of bovine heart, rat heart, and rat skeletal muscle were chromatographically separated and the fractions tested for their ability to maintain the survival of dissociated sympathetic, parasympathetic, and sensory neurones. Bovine heart contained at least five, rat heart at least six, and rat skeletal muscle at...

journal_title：Journal of neuroscience research

authors： Bonyhady RE,Hendry IA,Hill CE,Watters DJ

更新日期：1985-01-01 00:00:00

abstract：:Alterations in the 5-HT2A receptor gene expression in the prefrontal cortex have been suggested to play a role in the pathophysiology and pharmacotherapy of schizophrenia. This study measured mRNA encoding 5-HT2A receptor in the left superior frontal gyrus from chronic elderly schizophrenics (n = 21) with varying neur...

journal_title：Journal of neuroscience research

authors： Hernandez I,Sokolov BP

更新日期：2000-01-15 00:00:00

abstract：:The high circulating levels of leptin in neonatal rodents do not seem to be regulating energy balance at this age, but rather may play an important role for brain development. We tested the hypothesis that high neonatal leptin levels modify hippocampal function and production of synaptic proteins with possible long-te...

journal_title：Journal of neuroscience research

authors： Walker CD,Long H,Williams S,Richard D

更新日期：2007-03-01 00:00:00

abstract：:The applications of neural progenitor cells in clinical therapy for neural degeneration, such as Parkinson's disease, Huntington's disease, and cerebral infarction, have long been explored widely. It had been suggested that these cells may block the apoptosis of ischemia-induced neuronal damage and may themselves resi...

journal_title：Journal of neuroscience research

authors： Hsieh WY,Hsieh YL,Liu DD,Yang SN,Wu JN

更新日期：2003-01-15 00:00:00

abstract：:The Rho GTPases are important regulators of neurite outgrowth and pathfinding. We have recently reported that a Rho-family guanine nucleotide exchange factor, GEFT, modulates dendrite spine morphology and basal neurite outgrowth in primary hippocampal neurons and Neuro2A cells, respectively. Here we demonstrate that G...

journal_title：Journal of neuroscience research

authors： Bryan BA,Cai Y,Liu M

更新日期：2006-05-15 00:00:00

abstract：:In eukaryotes, mitochondria are critical for cellular bioenergetics and mediating apoptosis. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) is an important regulator of mitochondrial biogenesis and function. However, the role of PGC-1alpha in neuronal a...

journal_title：Journal of neuroscience research

authors： Liang J,Yang Y,Zhu X,Wang X,Chen R

更新日期：2010-07-01 00:00:00

abstract：:Haptoglobin (Hp), an acute-phase response protein, is typically increased in the serum of adults after acute tissue injury. It is an antioxidant and may function as an injury-induced neuroprotective protein. However, the source of increased Hp is not clear. To investigate its source, we compared its time course expres...

journal_title：Journal of neuroscience research

authors： Yang S,Ma Y,Liu Y,Que H,Zhu C,Liu S

更新日期：2013-02-01 00:00:00

abstract：:Chronic alcohol consumption has adverse effects on the central nervous system, affecting some hippocampal and hypothalamic functions. In this study we tempted to demonstrate that some of these modifications could involve impairment of neurotrophic factors. Three experimental groups of male Sprague Dawley rats were stu...

journal_title：Journal of neuroscience research

authors： Tapia-Arancibia L,Rage F,Givalois L,Dingeon P,Arancibia S,Beaugé F

更新日期：2001-01-15 00:00:00

abstract：:A number of cytokines and growth factors may affect astrocyte proliferation and functions. Transforming growth factor-beta 1 (TGF-beta 1) is a pleiotropic cytokine which exerts multiple effects on growth and differentiation of different cell types. TGF-beta 1 is present in low amounts in the normal brain. TGF-beta 1 g...

journal_title：Journal of neuroscience research

authors： Vergeli M,mazzanti B,Ballerini C,Gran B,Amaducci L,Massacesi L

更新日期：1995-01-01 00:00:00

abstract：:The effects of the environmental contaminants methylmercury (MeHg) and inorganic mercury (HgCl(2)) on cell viability, intracellular calcium concentration ([Ca(2+)](i)), and reactive oxygen species (ROS) generation were studied in rat cerebellar granule neuron cultures using fluorescent methods. MeHg exhibited an LC(50...

journal_title：Journal of neuroscience research

authors： Gassó S,Cristòfol RM,Selema G,Rosa R,Rodríguez-Farré E,Sanfeliu C

更新日期：2001-10-01 00:00:00

abstract：:Fibroblast growth factor 2 (FGF2) exhibits pleiotropic functions during embryogenesis. In neural development, both pro- and antineurogenic activities of FGF2 have been described in the differentiation of neuronal progenitors into postmitotic neurons. We used cultured neural stem cells (NSCs) derived from rat embryonic...

journal_title：Journal of neuroscience research

authors： Tsai RY,Kim S

更新日期：2005-10-15 00:00:00

abstract：:In culture, cerebellar granule neurons die of apoptosis in serum-free media containing a physiologic level of K(+) but survive in a depolarizing concentration of K(+) or when insulin-like growth factor 1 (IGF-1) is added. Both Akt/PKB activation and caspase-3 inhibition were implicated as the underlying neuroprotectiv...

journal_title：Journal of neuroscience research

authors： Zhong J,Deng J,Huang S,Yang X,Lee WH

更新日期：2004-03-15 00:00:00

abstract：:In many regions of the rat central nervous system, oligodendrocytes develop from migratory A2B5+ precursor cells. In the rat spinal cord, during early embryonic development the capacity for oligodendrogenesis appears to be restricted to ventral regions of the spinal cord, while cultures of postnatal rat spinal cord co...

journal_title：Journal of neuroscience research

authors： Fok-Seang J,Miller RH

更新日期：1994-02-01 00:00:00

abstract：:The male preponderance in autism prevalence has brought together the disparate topics of sex/gender and autism research. Two directions of neuroimaging studies on the relationships between sex/gender and autism may inform male-specific risk mechanisms and female-specific protective mechanisms of autism. First, we revi...

journal_title：Journal of neuroscience research

authors： Lai MC,Lerch JP,Floris DL,Ruigrok AN,Pohl A,Lombardo MV,Baron-Cohen S

更新日期：2017-01-02 00:00:00

abstract：:Iron deficiency and chronic mild carbon monoxide (CO) exposure are nutritional and environmental problems that can be experienced simultaneously. We examined the effects of chronic mild CO exposure and iron availability on auditory development in the rat. We propose that chronic mild CO exposure creates an oxidative s...

journal_title：Journal of neuroscience research

authors： Webber DS,Lopez I,Korsak RA,Hirota S,Acuna D,Edmond J

更新日期：2005-06-01 00:00:00

abstract：:Early studies of murine experimental autoimmune encephalomyelitis (EAE) induced with myelin basic protein (MBP) divide various mouse strains into either "susceptible" or "resistant" phenotypes. Resistance is defined as lack of encephalitogenic responses after active immunization or adoptive transfer. It is now becomin...

journal_title：Journal of neuroscience research

authors： Shaw MK,Kim C,Hao HW,Chen F,Tse HY

更新日期：1996-09-15 00:00:00

abstract：:An angiotensin 2 type 1 receptor blocker, olmesartan, and a calcium channel blocker, azelnidipine, possess not only an antihypertensive effect but also an antioxidative effect and other beneficial effects. In the present study, we examined the efficacy of olmesartan and azelnidipine monotherapy (2 mg/kg or 10 mg/kg ea...

journal_title：Journal of neuroscience research

authors： Omote Y,Deguchi K,Kono S,Liu W,Kurata T,Hishikawa N,Yamashita T,Ikeda Y,Abe K

更新日期：2014-10-01 00:00:00

abstract：:The expression of gangliosides of the lactosylceramide (LC) and of the gangliotetraosylceramide (GTC) series on the surface of cells from rat embryonic cerebellar tissue was investigated by double-color indirect immunofluorescence. GD3 was assumed to be representative of LC and was detected using a specific monoclonal...

journal_title：Journal of neuroscience research

authors： Gravotta D,Ferreira A,Busciglio J,Caceres A,Landa CA,Maccioni HJ

更新日期：1990-02-01 00:00:00