Characterization of novel intramedullary nailing method for treating femoral shaft fracture through finite element analysis.

abstract：:MicroRNA (miR)-202 has been reported to be involved in the regulation of human cancer progression including bladder cancer, non-small cell lung cancer, pancreatic cancer and esophageal squamous cell carcinoma. However, the function of miR-202 in prostate cancer remains largely unknown. The present study demonstrated t...

journal_title：Experimental and therapeutic medicine

authors： Zhang S,Cai J,Xie W,Luo H,Yang F

更新日期：2018-08-01 00:00:00

abstract：:A mutation in the IIb sodium phosphate transporter SLC34A2 gene has recently been described in pulmonary alveolar microlithiasis (PAM) patients. Experiments in this study were aimed at confirming the role of the gene product in PAM by comparing phosphorylated products in extracellular fluid of alveolar epithelial cell...

journal_title：Experimental and therapeutic medicine

authors： Ma T,Qu D,Yan B,Zhang Q,Ren J,Hu Y

更新日期：2018-01-01 00:00:00

abstract：:An accessory middle cerebral artery (AMCA), which mainly acts in the collateral circulation of the middle cerebral artery (MCA), is a rare anatomic malformation. Similar to other intracranial vessels, cerebrovascular disease can occur in the AMCA. However, the development of an arteriovenous malformation (AVM) in the ...

journal_title：Experimental and therapeutic medicine

authors： Li K,Guo Y,Qu L,Xu B,Xu K,Yu J

更新日期：2018-09-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) may lead to physical and pathological damage and has been a focus of research for decades. Evaluating tensile damage caused by deformation in ICH is an important component of damage assessment for correct diagnosis and treatment. Traditional research on ICH paid little attention to quant...

journal_title：Experimental and therapeutic medicine

authors： Ren P,Wang BC,Wang YZ,Hao SL,Guo TW,Li XF

更新日期：2018-12-01 00:00:00

abstract：:Aldehyde dehydrogenase 2 (aldh2) serves an important role in the development of organ injury. Therefore, the present study investigated the effects of aldh2 on the oxidative stress response in a mouse model of ketamine-induced cystitis (KIC). A total of 60 8-week-old male Institute of Cancer Research wild-type (WT) mi...

journal_title：Experimental and therapeutic medicine

authors： Xi XJ,Chen SH,Mi H

更新日期：2020-11-01 00:00:00

abstract：:The objective of the present study was to observe the therapeutic effect of radiation delivered via a 32P source on Graves' ophthalmopathy. A32P solution was injected into a 10-ml vacuum flask held inside a lead container. A window was cut in the lead, generating a treatment beam. Radiation was given to four areas: Th...

journal_title：Experimental and therapeutic medicine

authors： Hao HT,Wang Y,Wang X,Luan S,Cui J,Chen Y,Cui YL

更新日期：2017-10-01 00:00:00

abstract：:Cnidium officinale Makino and Capsella bursa-pastoris are used as traditional herbs with diverse medicinal effects, including the inhibition of inflammation, reduction of blood pressure and as diuretics, however, the anti-cancer effects of C. officinale Makino and C. bursa-pastoris are poorly defined. The aims of this...

journal_title：Experimental and therapeutic medicine

authors： Lee KE,Shin JA,Hong IS,Cho NP,Cho SD

更新日期：2013-03-01 00:00:00

abstract：:Lung cancer is among the most common causes of cancer-related mortality. It has a high mortality rate and resistance to chemotherapy due to its high metastatic potential. Naringenin, a bioactive compound identified in several fruits, displays anti-inflammatory and antitumor effects. Furthermore, naringenin mitigates t...

journal_title：Experimental and therapeutic medicine

authors： Chang HL,Chang YM,Lai SC,Chen KM,Wang KC,Chiu TT,Chang FH,Hsu LS

更新日期：2017-02-01 00:00:00

abstract：:The alleviation of brain injury is a key issue following cardiopulmonary resuscitation (CPR). Hydrogen sulfide (H2S) is hypothesized to be involved in the pathophysiological process of ischemia-reperfusion injury, and exerts a protective effect on neurons. The aim of the present study was to investigate the effects of...

journal_title：Experimental and therapeutic medicine

authors： Lin JY,Zhang MW,Wang JG,Li H,Wei HY,Liu R,Dai G,Liao XX

更新日期：2016-02-01 00:00:00

abstract：:Excision repair cross-complementation group 1 (ERCC1) protein has been associated with cisplatin resistance. The objective of this study was to investigate the correlation between ERCC1 protein levels and the therapeutic effect of individualized therapy in advanced non-small cell lung cancer (NSCLC). A total of 190 ad...

journal_title：Experimental and therapeutic medicine

authors： Gao Z,Han B,Shen J,Gu A,Qi D,Huang J,Shi C,Xiong L,Zhao Y,Jiang L,Wang H,Chen Y

更新日期：2011-09-01 00:00:00

abstract：:This study was designed to assess the relationship between changes in peripheral inflammatory factors of patients complicated with non-alcoholic fatty liver disease (NAFLD) undergoing coronary artery bypass grafting (CABG) before and after operation, and their prognosis. A total of 68 patients with stable angina pecto...

journal_title：Experimental and therapeutic medicine

authors： Wang L,Li Y,Gong X

更新日期：2018-01-01 00:00:00

abstract：:Abnormalities in insulin hormone levels leads to a hyperglycemic condition of diabetic mellitus. Hyperglycemia seriously induces organ and system destructions. The excessive accumulation of collagen fiber deposits occurs in inflammatory and reorganization processes of chronic liver diseases in type I insulin-dependent...

journal_title：Experimental and therapeutic medicine

authors： Komolkriengkrai M,Nopparat J,Vongvatcharanon U,Anupunpisit V,Khimmaktong W

更新日期：2019-08-01 00:00:00

abstract：:Phosphocitrate (PC) and its analogue, PC-β ethyl ester, inhibit articular cartilage degeneration in Hartley guinea pigs. However, the underlying molecular mechanisms remain unclear. The present study aimed to investigate the hypothesis that PC exerted its disease-modifying effect on osteoarthritis (OA), in part, by in...

journal_title：Experimental and therapeutic medicine

authors： Sun Y,Kiraly AJ,Cox M,Mauerhan DR,Hanley EN Jr

更新日期：2018-04-01 00:00:00

abstract：:The aim of the present study was to summarize the clinical characteristics of nocardiosis caused by Nocardia otitidiscaviarum in order to improve the knowledge of nocardiosis. A case of dissemination nocardiosis caused by N. otitidiscaviarum in an immunocompetent host is reported and the associated literature reviewed...

journal_title：Experimental and therapeutic medicine

authors： Jiang Y,Huang A,Fang Q

更新日期：2016-11-01 00:00:00

abstract：:The pathogenesis of acute liver failure has not been fully elucidated. The present study investigated the effects of the serum from patients with hepatitis E virus (HEV)-related acute liver failure on human liver cell survival and apoptosis, and evaluated the protective effects of anti-lipopolysaccharide(LPS) antibody...

journal_title：Experimental and therapeutic medicine

authors： Wu F,Wang M,Tian D

更新日期：2014-01-01 00:00:00

abstract：:The aim of the present study was to examine the clinical value of continuously monitoring serum CC16 levels in diagnosing pulmonary contusion, estimating its severity degree and predicting disease progression. Thirty-one acute trauma patients with lung contusion diagnosed by chest computed tomography (CT) were include...

journal_title：Experimental and therapeutic medicine

authors： Wen MN,Zhao G,Zhang JY,Zhao YH

更新日期：2017-09-01 00:00:00

abstract：:Various types of complications arising from intravenous indwelling needles have become a challenge in clinical care. It is urgent to seek a simple and cost-effective method for prevention and treatment of phlebitis. We investigated the roles of mirabilite in preventing and treating phlebitis caused by intravenous indw...

journal_title：Experimental and therapeutic medicine

authors： Lu Y,Hao C,He W,Tang C,Shao Z

更新日期：2018-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/etm.2015.2860.]. ...

journal_title：Experimental and therapeutic medicine

authors： Liu Y,Xiao J,Shi X,Hao G,Chen Q,Zhou J,Wei X

更新日期：2019-04-01 00:00:00

abstract：:The aim of the present study was to evaluate the predictive efficiency of mean platelet volume (MPV) and platelet size deviation width (PDW) for bone marrow failure (BMF) in thrombocytopenic patients. Platelet count, MPV and PDW data were retrieved from the records of 574 unselected thrombocytopenic patients from betw...

journal_title：Experimental and therapeutic medicine

authors： Xu RL,Zheng ZJ,Ma YJ,Hu YP,Zhuang SH

更新日期：2013-01-01 00:00:00

abstract：:Platelet-rich plasma (PRP) is blood plasma containing a high number of platelets that release growth factors for wound healing and tissue regeneration. In the present study, the feasibility of improving PRP therapy by using chitosan that exhibits high platelet activation ability was investigated. A total of 13 chitosa...

journal_title：Experimental and therapeutic medicine

authors： Hattori H,Ishihara M

更新日期：2017-03-01 00:00:00

abstract：:The DNA methylation inhibitor 5-aza-2'-deoxycytidine (5-aza-CdR) is widely used as an anticancer drug for the treatment of leukemia and solid tumors. Gastric cancer (GC) patients who were positive for caudal type homeobox transcription factor 2 (CDX2) expression showed a higher survival rate compared with those who we...

journal_title：Experimental and therapeutic medicine

authors： Zhang JF,Zhang JG,Kuai XL,Zhang H,Jiang W,Ding WF,Li ZL,Zhu HJ,Mao ZB

更新日期：2013-03-01 00:00:00

abstract：:Infantile neuroaxonal dystrophy (INAD) is a rare neurodegenerative disorder. Phospholipase A2 group VI (PLA2G6) gene mutations have been identified in the majority of individuals with INAD. The present case report is on a Chinese female pediatric patient (age, 18 months) diagnosed with INAD with deafness. To date, onl...

journal_title：Experimental and therapeutic medicine

authors： Wang B,Wu,Tang J

更新日期：2018-08-01 00:00:00

abstract：:Transplantation using bone marrow mesenchymal stem cells (BMSCs) is emerging as a potential regenerative therapy after ischemic attacks in the brain. However, it has been questioned because very few transplanted BMSCs are detected homing to and survived in the ischemic region. Improving the cell viability and migratio...

journal_title：Experimental and therapeutic medicine

authors： Yu J,Liu XL,Cheng QG,Lu SS,Xu XQ,Zu QQ,Liu S

更新日期：2016-09-01 00:00:00

abstract：:Pelvic organ prolapse (POP) is a common and distressing health problem in adult women, but the pathophysiological mechanism is yet to be fully elucidated. Previous studies have indicated that oxidative stress may be associated with POP. Thus, the aim of the present study was to investigate the oxidative status of pelv...

journal_title：Experimental and therapeutic medicine

authors： Fang G,Hong L,Liu C,Yang Q,Zhang Q,Li Y,Li B,Wu D,Wu W,Shi H

更新日期：2018-10-01 00:00:00

abstract：:The aim of our study was to analyze the role of toll-like receptor 4 (TLR4)/nuclear factor (NF)-κB signal pathway on Hepcidin regulation in non-alcoholic fatty liver disease (NAFLD). A total of 60 male Sprague-Dawley rats were randomly divided into the control, NAFLD and intervention groups. Rats in the control group ...

journal_title：Experimental and therapeutic medicine

authors： Chen W,Wang X,Huang LI,Liu BO

更新日期：2016-01-01 00:00:00

abstract：:There is little information regarding the recent trend of synchronous and metachronous pulmonary metastases in patients with primary colorectal cancer. We investigated patients with sporadic colorectal cancer who underwent surgery in our department between 1990 and 2009. Clinicopathological parameters of primary cance...

journal_title：Experimental and therapeutic medicine

authors： Nozawa H,Sunami E,Nakajima J,Nagawa H,Kitayama J

更新日期：2012-03-01 00:00:00

abstract：:Phthalates are confirmed to have toxic effects on the reproductive system and are likely to have further damaging actions in humans. The present study explored the molecular mechanisms of the toxic effect of mono-(2-ethylhexyl) phthalate (MEHP) on mouse Sertoli cells. Cell apoptosis and proliferation assays were used ...

journal_title：Experimental and therapeutic medicine

authors： Wang L,Dou T,Li S,Liu Y

更新日期：2019-04-01 00:00:00

abstract：:MYH is an important enzyme in combating DNA oxidative stress in the occurrence and development of various types of tumors. To investigate the correlation between expression of the DNA repair enzyme MYH in esophageal squamous cell carcinoma and 8-oxoguanine (8-oxoG) oxidative damage, as well as the clinical significanc...

journal_title：Experimental and therapeutic medicine

authors： Shen K,Ji Y,Chen GQ,Huang B,Zhang X,Wu S,Yu GP,Wang XC

更新日期：2011-11-01 00:00:00

abstract：:Alcohol use disorder (AUD) is a primary, chronic and relapsing disease of brain reward, motivation and memory, which is associated with several comorbidities, including major depression and post-traumatic stress disorder. It has been revealed that Ibudilast (IBUD), a dual inhibitor of phosphodiesterase-4 and -10 and o...

journal_title：Experimental and therapeutic medicine

authors： Petralia MC,Mazzon E,Mangano K,Fagone P,Di Marco R,Falzone L,Basile MS,Nicoletti F,Cavalli E

更新日期：2020-03-01 00:00:00

abstract：:The application of biomarkers in melanoma prognosis has been well recognized. However the ability of a single biomarker to predict melanoma patient outcome is usually limited. We previously examined the expression of ten biomarkers (Bim, BRG1, BRMS1, CTHRC1, ING4, NQO1, NF-κB-p50, PUMA, SNF5 and SOX4) in melanomas. To...

journal_title：Experimental and therapeutic medicine

authors： Li J,Zhang Z,Li G

更新日期：2011-01-01 00:00:00