Oxidative status of cardinal ligament in pelvic organ prolapse.

abstract：:This study investigated changes in the level of serum 25-OH vitamin D [25-hydroxyvitamin D, 25(OH)D] in patients with non-alcoholic fatty liver disease (NAFLD) and the correlation between the severity of NAFLD and 25(OH)D. A retrospective analysis was performed on 385 NAFLD patients (NAFLD group) admitted to the Zhong...

journal_title：Experimental and therapeutic medicine

authors： Cai J,Zhang Z,Liu J,Xiao X,Wang C,Deng M,Chen L

更新日期：2020-03-01 00:00:00

abstract：:The pathogenesis of acute liver failure has not been fully elucidated. The present study investigated the effects of the serum from patients with hepatitis E virus (HEV)-related acute liver failure on human liver cell survival and apoptosis, and evaluated the protective effects of anti-lipopolysaccharide(LPS) antibody...

journal_title：Experimental and therapeutic medicine

authors： Wu F,Wang M,Tian D

更新日期：2014-01-01 00:00:00

abstract：:The aim of the study was to detect the expression of interleukin-1β (IL-1β) in serum of patients with perimenopausal non-organic sleep disorder (PNSD) and to study the relationship between IL-1β and the severity of insomnia and liver depression, so as to benefit the prevention of PNSD. A total of 268 cases of perimeno...

journal_title：Experimental and therapeutic medicine

authors： Li H,Chen Y,Wu H,Huang J,Ma K,Zheng J,Lv S

更新日期：2019-01-01 00:00:00

abstract：:Successful eyelid reconstructions have been reported when using an axial nasal chondromucosal flap based on the dorsal nasal artery. The present study aimed to present a detailed anatomical description of the blood supply of the lateral nasal region and the angular artery, in order to propose the angular vessels as a ...

journal_title：Experimental and therapeutic medicine

authors： Hou D,Fang L,Zhao Z,Zhou C,Yang M

更新日期：2013-03-01 00:00:00

abstract：:Alteration of behavior and PSD proteins in cerebral cortex and hippocampal synaptosome in the Alzheimer's disease (AD) mouse model were determined. AD was established by intraperitoneal injection of streptozotocin (STZ) in neonatal mice (intraperitoneal AD group) or intracerebroventricular injection of STZ in adult mi...

journal_title：Experimental and therapeutic medicine

authors： Zhang Y,Ding R,Wang S,Ren Z,Xu L,Zhang X,Zhao J,Ding Y,Wu Y,Gong Y

更新日期：2018-09-01 00:00:00

abstract：:In the present study, the predictive value of glycosylated hemoglobin (HbA1c), microalbuminuria (24 h mAlb) and serum cystatin C (Cys-C) levels on the outcome of pregnancy in patients with gestational diabetes mellitus (GDM) was investigated. Samples of 144 females with GDM and 117 normal pregnant females as controls ...

journal_title：Experimental and therapeutic medicine

authors： Jin H

更新日期：2020-02-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) has been demonstrated to affect the oxidative stress status in several in vitro, in vivo and clinical studies. The aim of the present study was to evaluate the effect of a GLP-1 analogue, exenatide, on oxidative stress parameters and apoptotic markers in testicular cells in an iron over...

journal_title：Experimental and therapeutic medicine

authors： Yesil S,Sungu N,Kilicarslan A,Kuskonmaz SM,Kara H,Kucuk A,Polat F,Kavutcu M,Arslan M

更新日期：2018-12-01 00:00:00

abstract：:The functions of telomeric repeat-binding factor 1 (TRF1) and 2 (TRF2) in oral carcinogenesis are largely unexplored. This study examined the relationship between the expression of TRF1 and TRF2 and clinicopathological variables and survival in oral cavity squamous cell carcinoma (OCSCC). Western blotting and immunohi...

journal_title：Experimental and therapeutic medicine

authors： Chuang HC,Chen CH,Huang CC,Fang FM,Tsai HT,Chien CY

更新日期：2011-01-01 00:00:00

abstract：:Serum thymidine kinase 1 (STK1) is a reliable proliferation marker in most solid tumors, including gastric cancer. The aim of this study was to evaluate whether STK1 levels are related to the tumor response to chemotherapy and survival in advanced gastric cancer. The results showed that the average STK1 level in patie...

journal_title：Experimental and therapeutic medicine

authors： Liu Y,Ling Y,Qi Q,Tang Y,Xu J,Tong Z,Sheng G,Yang Q,Pan Y

更新日期：2011-11-01 00:00:00

abstract：:Hypertension is a very common cardiovascular disorder, however, the molecular mechanism underlying this disease remains poorly understood. Recently, an increasing number of studies have demonstrated that mitochondrial (mt)DNA mutations serve important roles in the pathogenesis of hypertension. The current study report...

journal_title：Experimental and therapeutic medicine

authors： Lin L,Cui P,Qiu Z,Wang M,Yu Y,Wang J,Sun Q,Zhao H

更新日期：2019-03-01 00:00:00

abstract：:Intervertebral disc degeneration (IDD) is considered to be the main cause of many spinal disorders; however, its underlying pathophysiology is not clearly understood. Recent studies indicate that excessive mechanical loading may serve a major role in the initiation of IDD. The aim of the present study was to explore t...

journal_title：Experimental and therapeutic medicine

authors： Bai X,Wang D,Zhou M,Xu C,Li W,Tao H,He Q,Ruan D

更新日期：2017-04-01 00:00:00

abstract：:Acute cerebral ischemia/reperfusion injury (ACIR) rat model was used to investigate the effect of spermine on oxidative stress and apoptosis. Sixty healthy and clean male Sprague-Dawley rats were randomly divided into 3 groups: The sham-operated group (n=12), the model group (n=12) and the experiment group (n=36). The...

journal_title：Experimental and therapeutic medicine

authors： Du H,Ming X,Zhou S

更新日期：2017-07-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are a novel class of transcripts, which are pervasively transcribed in the genome and a have greatly unknown biological function. Previous studies have identified that lncRNAs serve an important role in embryonic development. However, the function and mechanism of lncRNAs in the developm...

journal_title：Experimental and therapeutic medicine

authors： Gao L,Yin J,Wu W

更新日期：2016-06-01 00:00:00

abstract：:Chemotherapy-induced anorexia (CIA), which may lead to severe nutrition-associated problems, is a common complication associated with anti-cancer therapies. In the present study, the anti-anorexigenic effect of electroacupuncture (EA) was explored through assessing a change in appetite-associated peptides and c-Fos ex...

journal_title：Experimental and therapeutic medicine

authors： Kang KS,Huh W,Bang Y,Choi HJ,Baek JY,Song JH,Kang JW,Kim TH

更新日期：2019-04-01 00:00:00

abstract：:The aim of the present study was to investigate whether modified Huangqi Chifeng decoction (MHCD) could be an effective treatment against Doxorubicin-induced nephrosis in rats and whether it regulates autophagy via the phosphoinositide-3 kinase/mammalian target of rapamycin (PI3K/mTOR) signaling pathway. A total of 40...

journal_title：Experimental and therapeutic medicine

authors： Yu ZK,Yang B,Zhang Y,Li LS,Zhao JN,Hao W

更新日期：2018-09-01 00:00:00

abstract：:Infantile neuroaxonal dystrophy (INAD) is a rare neurodegenerative disorder. Phospholipase A2 group VI (PLA2G6) gene mutations have been identified in the majority of individuals with INAD. The present case report is on a Chinese female pediatric patient (age, 18 months) diagnosed with INAD with deafness. To date, onl...

journal_title：Experimental and therapeutic medicine

authors： Wang B,Wu,Tang J

更新日期：2018-08-01 00:00:00

abstract：:The present study was performed to investigate the prognostic value of coronary computed tomography angiography (CTA) results for asymptomatic patients with coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM). A total of 164 asymptomatic patients with T2DM were enrolled at Weifang Traditional Chinese Hosp...

journal_title：Experimental and therapeutic medicine

authors： Tian P,Zheng X,Li M,Li W,Niu Q

更新日期：2019-07-01 00:00:00

abstract：:The intermingling of two malignant neoplasms within the same cutaneous tumor is rare. No consensus has been reached for a clear definition and categorization. In the current study, we describe a cutaneous neoplasm; a squamomelanocytic tumor (SMT) with histological features combining those of a squamous cell carcinoma ...

journal_title：Experimental and therapeutic medicine

authors： Wang HY,Zhang XB,Su RJ,Wang CB,Liu X

更新日期：2013-03-01 00:00:00

abstract：:The binary toxin Clostridium difficile transferase (CDT) is frequently observed in C. difficile strains and is associated with an increased severity of C. difficile infection. CDT-producing C. difficile infections cause higher fatality rates than infections with CDT negative isolates. Thus, the rapid and accurate iden...

journal_title：Experimental and therapeutic medicine

authors： Yu L,Li H,Zhao X,Wang X,Wei X,Lin W,Li P,Cui L,Yuan J

更新日期：2017-11-01 00:00:00

abstract：:Air pollution can highly impact the respiratory system in healthy individuals. Studies have indicated that particles with an aerodynamic diameter of ≤2.5 µm (PM2.5) can be considered to be harmful for lung alveoli and bronchial epithelium cells. PM2.5 can be directly inhaled and can deeply penetrate into the lung alve...

journal_title：Experimental and therapeutic medicine

authors： Han X,Zhuang Y

更新日期：2021-01-01 00:00:00

abstract：:Valvular heart disease (VHD) is caused by either damage or defect in one of the four heart valves, aortic, mitral, tricuspid or pulmonary. Defects in these valves can be congenital or acquired. Age, gender, tobacco use, hypercholesterolemia, hypertension, and type II diabetes contribute to the risk of disease. VHD is ...

journal_title：Experimental and therapeutic medicine

authors： Zeng YI,Sun R,Li X,Liu M,Chen S,Zhang P

更新日期：2016-04-01 00:00:00

abstract：:In the present study, we demonstrate that the degeneration of intervertebral discs is caused by ageing and apoptosis of matrix cells. Apoptosis is as essential as the function of proteoglycan synthesis in assessing the possible degeneration of intervertebral discs; paeoniflorin (PF) induces cytoprotective effects on v...

journal_title：Experimental and therapeutic medicine

authors： Chen SQ,Lin JP,Zheng QK,Chen SJ,Li M,Lin XZ,Wang SZ

更新日期：2015-12-01 00:00:00

abstract：:A number of microRNAs (miRs) have been revealed to be involved in the development of osteoporosis, including postmenopausal osteoporosis. The aim of the present study was to investigate miR-135a-5p expression and the cellular function of miR-135a-5p and its underlying mechanism in postmenopausal osteoporosis. miR-135a...

journal_title：Experimental and therapeutic medicine

authors： Shi X,Zhang Z

更新日期：2019-10-01 00:00:00

abstract：:The chest X-ray is routinely requested by pediatricians for children with suspected pneumonia, but has been demonstrated to be an insensitive method with relatively low accuracy. Computed tomography (CT) allows for the characterization of the consolidation in pneumonia but has a high risk of radiation exposure in chil...

journal_title：Experimental and therapeutic medicine

authors： Yan C,Hui R,Lijuan Z,Zhou Y

更新日期：2020-02-01 00:00:00

abstract：:High-mobility group box 1 (HMGB1) is released after focal cerebral ischemia/reperfusion (I/R), and aggravates brain tissue damage. Ginsenoside Rb1 (Rb1), isolated from Panax ginseng, has been reported to inhibit I/R-induced cell death in the brain. The present study aimed to investigate the protective ability of GRb1 ...

journal_title：Experimental and therapeutic medicine

authors： Liu A,Zhu W,Sun L,Han G,Liu H,Chen Z,Zhuang L,Jiang W,Xue X

更新日期：2018-10-01 00:00:00

abstract：:This study investigated the expression of C-C chemokine receptor type 3 (CCR3), transcription factor SOX5 (SOX5) and microtubule-associated protein 1 light chain 3 (LC3) in patients with elderly onset rheumatoid arthritis (EORA) and the clinical significance. Ninety patients with elderly onset rheumatoid arthritis wer...

journal_title：Experimental and therapeutic medicine

authors： Wang J,Zhao Q

更新日期：2017-10-01 00:00:00

abstract：:Here, we present a case of post-operative liver metastases from pancreatic head cancer in a patient with leukocytopenia, who was safely treated by hepatic arterial infusion (HAI) chemotherapy consisting of gemcitabine and 5-FU. The patient was a 61-year-old woman who underwent pancreaticoduodenectomy for pancreatic he...

journal_title：Experimental and therapeutic medicine

authors： Tajima H,Ohta T,Kitagawa H,Sakai S,Makino I,Hayashi H,Nakagawara H,Onishi I,Takamura H,Ninomiya I,Fushida S,Tani T,Fujimura T,Kayahara M,Koda W,Minami T,Ryu Y,Sanada J,Matsui O

更新日期：2010-11-01 00:00:00

abstract：:Extramedullary hematopoiesis (EMH) is defined as hematopoiesis occurring in organs outside of the bone marrow. The present report describes two cases of thalassemic patients with paraspinal medullary hematopoiesis and analyzes the clinical manifestations, imaging, pathology, diagnosis and treatment of EMH. In addition...

journal_title：Experimental and therapeutic medicine

authors： Zhang HZ,Li Y,Liu X,Chen BR,Yao GH,Peng YN

更新日期：2016-12-01 00:00:00

abstract：:Eosinophilia has been implicated in the pathophysiology of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, the role of eosinophil activation in the development of AECOPD remains unclear. In the present study, the reliability of plasma levels of eosinophil activation markers, including eo...

journal_title：Experimental and therapeutic medicine

authors： Yang QF,Lu TT,Shu CM,Feng LF,Chang HT,Ji QY

更新日期：2017-10-01 00:00:00

abstract：:Pulmonary embolism may escape prompt diagnosis since clinical symptoms and signs are nonspecific. The occurrence of syncope as the sole initial symptom in a previously healthy patient with no predisposing factors to embolism and no hemodynamic instability is extremely rare, which may have been a factor in the delayed ...

journal_title：Experimental and therapeutic medicine

authors： Jiang AG,Lu HY

更新日期：2013-05-01 00:00:00