Clinical study on the changes of lung-specific proteins: CC16 after lung contusion.

abstract：:MicroRNAs (miRs) are have been demonstrated to serve important functions in the genesis of human cancer, including colorectal cancer (CRC). The role of miR-6852 in CRC remains unknown. In this study, it was demonstrated that miR-6852 was underexpressed in CRC tissues compared with adjacent normal tissues. Moreover, th...

journal_title：Experimental and therapeutic medicine

authors： Cui BH,Hong X

更新日期：2018-08-01 00:00:00

abstract：:In order to identify and describe the effectiveness of transdermal testosterone pretreatment on poor ovarian responders, MEDLINE, EMBASE, the Cochrane library and the Chinese biomedical database were searched for randomized controlled trials (RCTs). Three RCTs, which compared the outcomes of female pretreatment with t...

journal_title：Experimental and therapeutic medicine

authors： Luo S,Li S,Li X,Qin L,Jin S

更新日期：2014-07-01 00:00:00

abstract：:Scarred uterus is caused by cesarean section surgery, and this condition affects further gestation and delivery in patients. Previous evidence suggested that resveratrol, a polyphenol compound, presents beneficial outcomes for patients with scarred uterus. Therefore, the aim of the present study was to analyze the eff...

journal_title：Experimental and therapeutic medicine

authors： Ma H,Qiao Z

更新日期：2018-06-01 00:00:00

abstract：:The present study aimed to investigate whether serum interleukin-6 (IL-6) expression levels were associated with the onset and progression of intervertebral disc degeneration (IDD). A comprehensive meta-analysis of the scientific literature from numerous electronic databases was performed, in order to obtain published...

journal_title：Experimental and therapeutic medicine

authors： Deng X,Zhao F,Kang B,Zhang X

更新日期：2016-04-01 00:00:00

abstract：:Infantile neuroaxonal dystrophy (INAD) is a rare neurodegenerative disorder. Phospholipase A2 group VI (PLA2G6) gene mutations have been identified in the majority of individuals with INAD. The present case report is on a Chinese female pediatric patient (age, 18 months) diagnosed with INAD with deafness. To date, onl...

journal_title：Experimental and therapeutic medicine

authors： Wang B,Wu,Tang J

更新日期：2018-08-01 00:00:00

abstract：:Coronary artery disease (CAD) is the first cause of morbidity and mortality worldwide. An important goal is to diagnose patients in early stages, in order to reduce acute cardiovascular events. The angiotensin-converting enzyme (ACE) is an important element for the cardiovascular system, through its actions on hydro-s...

journal_title：Experimental and therapeutic medicine

authors： Vladeanu MC,Bojan IB,Bojan A,Iliescu D,Badescu MC,Badulescu OV,Badescu M,Georgescu CA,Ciocoiu M

更新日期：2020-10-01 00:00:00

abstract：:The aim of the present study was to examine the effect of CCAAT enhancer binding protein β (C/EBPβ) on human breast cancer cells. The plasmids pCDH-C/EBPβ and pLKO.1-shC/EBPβ were constructed and were infected into MDA-MB-468 cells, to provide C/EBPβ overexpressing and C/EBPβ knockdown cells, respectively. Cell viabil...

journal_title：Experimental and therapeutic medicine

authors： Cao J,Wang M,Wang T

更新日期：2017-08-01 00:00:00

abstract：:Previous clinical trials have investigated the effect of glucocorticoid therapy in acute respiratory distress syndrome (ARDS), with controversial results, particularly with regard to the early administration of low dose glucocorticoid. The present meta-analysis aimed to assess whether the application of glucocorticoid...

journal_title：Experimental and therapeutic medicine

authors： Yang ZG,Lei XL,Li XL

更新日期：2017-04-01 00:00:00

abstract：:Homeobox protein Nxk-2.5 (Nkx2.5) is a homeobox transcription factor that promotes chamber-like myocardial gene expression. Data from a previous genome-wide association study suggested that Nkx2.5 may be associated with the genetic variation that underlies atrial fibrillation (AF). Nkx2.5 loss of function has been dem...

journal_title：Experimental and therapeutic medicine

authors： Chen J,Xu S,Li W,Wu L,Wang L,Li Y,Zhou W

更新日期：2019-12-01 00:00:00

abstract：:This study describes the case of a 41-year-old woman admitted for anterograde memory loss, right facial grimacing and right arm posturing that had begun 1 month previously. Cranial magnetic resonance-diffusion weighted imaging and -fluid-attenuated inversion recovery imaging revealed a hyperintense signal in the left ...

journal_title：Experimental and therapeutic medicine

authors： Liu J,Li M,Li G,Zhou C,Zhang R

更新日期：2016-01-01 00:00:00

abstract：:The aim of the present study was to analyze the mechanism by which nerve growth factor (NGF) promotes callus formation in mice with tibial fracture. NGF transgenic homozygotic mice and NGF wild homozygotic mice were selected to construct non-stabilized fracture model of tibia. The mice were sacrificed on days 7, 14 an...

journal_title：Experimental and therapeutic medicine

authors： Sang XG,Wang ZY,Cheng L,Liu YH,Li YG,Qin T,Di K

更新日期：2017-04-01 00:00:00

abstract：:The present study aimed to analyze the expression and effects of NUAK2 in gastric cancer and adjacent normal gastric tissues. The protein expression levels of NUAK2 were detected by western blot analysis. The effects of NUAK2 expression on the proliferation of gastric cancer cells was detected using an MTT and BrdU in...

journal_title：Experimental and therapeutic medicine

authors： Tang L,Tong SJ,Zhan Z,Wang Q,Tian Y,Chen F

更新日期：2017-02-01 00:00:00

abstract：:To suppress the invasion of hepatocellular carcinoma (HCC) cells into surrounding connective tissues during metastasis, we investigated the usefulness of sorafenib. In order to search for model cell lines, cell numbers were counted to reveal cell lines with the potential to proliferate in serum-free media. Cell prolif...

journal_title：Experimental and therapeutic medicine

authors： Tomizawa M,Shinozaki F,Sugiyama T,Yamamoto S,Sueishi M,Yoshida T

更新日期：2010-09-01 00:00:00

abstract：:The aim of the present study was to investigate whether magnolol, the essential component of the traditional Chinese medicine, Magnolia officinalis, can pass through liver X receptor α (LXRα), to subsequently play an important role in the lipid metabolic balance. Using a HepG2 human hepatoma cell line, mammalian cellu...

journal_title：Experimental and therapeutic medicine

authors： Xie NA,Hu C,Guo A,Liang H,DU P,Yin G

更新日期：2015-05-01 00:00:00

abstract：:The present study aimed to investigate the influence of mouse nerve growth factor (mNGF) on glial fibrillary acidic protein (GFAP) expression in neonatal rats with hypoxic-ischemic brain damage (HIBD). A total of 60 7-day-old neonatal rats were randomly divided into control, HIBD and mNGF groups (n=20). The rats in th...

journal_title：Experimental and therapeutic medicine

authors： Yin X,Dong L,Wei W,Wang Y,Chai Y,Feng Z

更新日期：2013-02-01 00:00:00

abstract：:Effects of propofol, midazolam and dexmedetomidine on patients with sepsis in intensive care unit (ICU) and on arterial blood gas (ABG) were studied. In total 429 ICU patients with sepsis, admitted to Renji Hospital, School of Medicine, Shanghai Jiaotong University from May 2015 to January 2019, were selected as resea...

journal_title：Experimental and therapeutic medicine

authors： Ding J,Chen Y,Gao Y

更新日期：2019-12-01 00:00:00

abstract：:The pathogenesis of acute liver failure has not been fully elucidated. The present study investigated the effects of the serum from patients with hepatitis E virus (HEV)-related acute liver failure on human liver cell survival and apoptosis, and evaluated the protective effects of anti-lipopolysaccharide(LPS) antibody...

journal_title：Experimental and therapeutic medicine

authors： Wu F,Wang M,Tian D

更新日期：2014-01-01 00:00:00

abstract：:Pulmonary mucormycosis, a relatively rare pulmonary fungal disease, is difficult to diagnose and lacks effective treatment. The present study reports the case of a 64-year-old patient who was treated successfully for pulmonary mucormycosis in Xuan Wu Hospital. The patient presented with low-grade fever and a productiv...

journal_title：Experimental and therapeutic medicine

authors： Luo Z,Zhang L

更新日期：2017-10-01 00:00:00

abstract：:Rhubarb has been used as an evacuant for thousands of years. However, recent research has indicated that rhubarb inhibits inflammation and protects organ function. In the current study, the use of rhubarb was investigated in patients with intra-abdominal hypertension (IAH). Specifically, its dual role in attenuating l...

journal_title：Experimental and therapeutic medicine

authors： Wan B,Zhang H,Yin J,Fu H,Chen Y,Yang L,Liu D,Lv T,Song Y

更新日期：2017-07-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) has been demonstrated to affect the oxidative stress status in several in vitro, in vivo and clinical studies. The aim of the present study was to evaluate the effect of a GLP-1 analogue, exenatide, on oxidative stress parameters and apoptotic markers in testicular cells in an iron over...

journal_title：Experimental and therapeutic medicine

authors： Yesil S,Sungu N,Kilicarslan A,Kuskonmaz SM,Kara H,Kucuk A,Polat F,Kavutcu M,Arslan M

更新日期：2018-12-01 00:00:00

abstract：:Spinal cord injury (SCI) may lead to a devastating and permanent loss of neurological function, which may place a great economic burden on the family of the patient and society. Methods for reducing the death of neuronal cells, inhibiting immune and inflammatory reactions, and promoting the growth of axons in order to...

journal_title：Experimental and therapeutic medicine

authors： Ji W,Hu S,Zhou J,Wang G,Wang K,Zhang Y

更新日期：2014-03-01 00:00:00

abstract：:The inactivation of the cyclin-dependent kinase inhibitor p16(INK4A) gene by hypermethylation is observed in numerous types of cancer. New findings indicate that DNA and histone methylation act in concert in gene silencing. In this study, we investigated the methylation status of the p16(INK4A) gene promoter and the h...

journal_title：Experimental and therapeutic medicine

authors： Yoruker EE,Mert U,Bugra D,Yamaner S,Dalay N

更新日期：2012-11-01 00:00:00

abstract：:Schisandrin B (SchB) is one of the primary active components of Schisandra chinensis (Turcz.) Baill., a traditional Chinese herb that has been used to treat insomnia for hundreds of years. Our previous studies revealed that SchB exerts sedative and hypnotic effects, increasing the content of γ-aminobutyric acid (GABA)...

journal_title：Experimental and therapeutic medicine

authors： Wang M,Li N,Jing S,Wang C,Sun J,Li H,Liu J,Chen J

更新日期：2020-12-01 00:00:00

abstract：:The aim of this study was to evaluate the feasibility of transjugular intrahepatic portosystemic shunts using FLUENCY expanded polytetraf luoroethylene (PTFE)-covered stents and the effect on the patency rate. A total of 114 cirrhotic patients who were treated by transjugular intrahepatic portosystemic stent shunt (TI...

journal_title：Experimental and therapeutic medicine

authors： Wu Q,Jiang J,He Y,Jiang T,Zhou S

更新日期：2013-01-01 00:00:00

abstract：:Action potential (AP) contours vary considerably between the fibers of normal adult and aged left atria. The underlying ionic and molecular mechanisms that mediate these differences remain unknown. The aim of the present study was to investigate whether the L-type calcium current (ICa.L) and the L-type Ca2+ channel of...

journal_title：Experimental and therapeutic medicine

authors： Gan TY,Qiao W,Xu GJ,Zhou XH,Tang BP,Song JG,Li YD,Zhang J,Li FP,Mao T,Jiang T

更新日期：2013-10-01 00:00:00

abstract：:Tumor hypoxia contributes to the development of resistance to chemotherapeutic drugs in several human cancer cell lines. Atovaquone, an anti-malaria drug approved by the US Food and Drug Administration, has recently demonstrated anti-cancer effects in vitro and in vivo in several cancer models. To assess the potential...

journal_title：Experimental and therapeutic medicine

authors： Fu C,Xiao X,Xu H,Lu W,Wang Y

更新日期：2020-12-01 00:00:00

abstract：:Clobetasol propionate (Clo) is a potent topical glucocorticoid and a potential remyelinating agent that has been approved by the U.S. Food and Drug Administration. However, the effect of Clo on neural stem cells (NSCs) remains largely unknown. The aim of the present study was to investigate the effect of Clo on the di...

journal_title：Experimental and therapeutic medicine

authors： Shi W,Bi S,Dai Y,Yang K,Zhao Y,Zhang Z

更新日期：2019-08-01 00:00:00

abstract：:We generated replication-defective adenovirus Ad-p53AIP1 and studied its anti-tumor efficacy both in vitro and in vivo. We demonstrated that Ad-p53AIP1 infection elicited high levels of p53AIP1 expression in cancer cells. We also found that Ad-p53AIP1 expression induced marked apoptosis and cell cycle arrest in HepG2 ...

journal_title：Experimental and therapeutic medicine

authors： Jiang Y,Chen H,Jia H,Xu Y,Liu G,Wang Y,Yang X,Lu Y

更新日期：2010-03-01 00:00:00

abstract：:This study was designed to investigate the correlation of vitamin D receptor (VDR) gene polymorphism with bronchial asthma in children. Seventy patients admitted to Daqing Longnan Hospital and diagnosed as bronchial asthma for the first time from April 2015 to May 2017 were selected as observation group. Patients rece...

journal_title：Experimental and therapeutic medicine

authors： Hou C,Zhu X,Chang X

更新日期：2018-03-01 00:00:00

abstract：:The present study aimed to evaluate whether thymosin α1 (Tα1) increases survival rates through the improvement of immunofunction and inhibition of hepatocyte apoptosis in rats with acute liver failure (ALF). A total of 25 rats were randomly divided into the control group (CG), the model group (MG) and the treatment gr...

journal_title：Experimental and therapeutic medicine

authors： Yang X,Chen Y,Zhang J,Tang T,Kong Y,Ye F,Zhang X,Liu X,Lin S

更新日期：2018-04-01 00:00:00