Abstract:
:The human connectome has become the very frequent subject of study of brain-scientists, psychologists and imaging experts in the last decade. With diffusion magnetic resonance imaging techniques, united with advanced data processing algorithms, today we are able to compute braingraphs with several hundred, anatomically identified nodes and thousands of edges, corresponding to the anatomical connections of the brain. The analysis of these graphs without refined mathematical tools is hopeless. These tools need to address the high error rate of the MRI processing workflow, and need to find structural causes or at least correlations of psychological properties and cerebral connections. Until now, structural connectomics was only rarely able of identifying such causes or correlations. In the present work we study the frequent neighbor sets of the most deeply investigated brain area, the hippocampus. By applying the Frequent Network Neighborhood mapping method, we identified frequent neighbor-sets of the hippocampus, which may influence numerous psychological parameters, including intelligence-related ones. We have found "Good Neighbor" sets, which correlate with better test results and also "Bad Neighbor" sets, which correlate with worse test results. Our study utilizes the braingraphs, computed from the imaging data of the Human Connectome Project's 414 subjects, each with 463 anatomically identified nodes.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Fellner M,Varga B,Grolmusz Vdoi
10.1038/s41598-020-68914-2subject
Has Abstractpub_date
2020-07-20 00:00:00pages
11967issue
1issn
2045-2322pii
10.1038/s41598-020-68914-2journal_volume
10pub_type
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