Abstract:
:Nettles are commonly consumed in South Africa, Europe and Asia and are used in traditional medicine to treat a variety of ailments. In this study, the nutritional value of the leaves of nettles (Laportea alatipes and Obetia tenax) was evaluated and compared, when cooked and uncooked. The results showed a decrease in the concentrations of crude protein, vitamin A, vitamin E and metals after cooking of nettles. Although cooking reduced the concentrations of essential elements in nettles, their contribution to the diet remained adequate. L. alatipes presented with reduced levels of Cd (from 1.86 to 0.810 mg kg-1) and Pb (from 2.87 to 1.88 mg kg-1) after cooking. Similarly, Cd (from 2.97 to 0.780 mg kg-1) and Pb (from 2.21 to 0.795 mg kg-1) levels in O. tenax decreased after cooking, demonstrating the significance of cooking. The antioxidant activity of the nettles was determined using the 2,2-diphenyl-l-picrylhydrazyl (DPPH) free radical and ferric reducing antioxidant power (FRAP) assays. The methanol extract of Obetia tenax showed high ferric reducing power whilst the radical scavenging activity was due to the presence of the bioactive molecule, β-carotene, in the plants which exhibited higher DPPH radical scavenging ability relative to test samples and standards. The in vitro antidiabetic activity of the extracts and compounds from the nettles was better than or comparable to that of the known standard, acarbose, which underscores the prospective antidiabetic properties of nettles. Overall, our study provides scientific validation for the ethno-medicinal use of nettles and supports their consumption, which highlights their potential as nutraceuticals.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Mahlangeni NT,Moodley R,Jonnalagadda SBdoi
10.1038/s41598-020-67055-wsubject
Has Abstractpub_date
2020-06-17 00:00:00pages
9762issue
1issn
2045-2322pii
10.1038/s41598-020-67055-wjournal_volume
10pub_type
杂志文章abstract::The MEN1 gene, which encodes the protein Menin, was investigated for its regulatory role in milk protein synthesis in mammary glands. Menin responds to nutrient and hormone levels via the PI3K/Akt/mTOR pathway. Bovine mammary epithelial cells and tissues were used as experimental models in this study. The results reve...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06054-w
更新日期:2017-07-14 00:00:00
abstract::By eliminating the spherical aberrations of microsphere we derived a simple but useful formula on the focusing of dielectric microsphere. On basis of this formula, not only can researchers determine the parameters of an optical microsphere system with super-resolution, but they can also perform parameter transformatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06146-7
更新日期:2017-07-18 00:00:00
abstract::The intercellular spreading of protein assemblies is a major factor in the progression of neurodegenerative disorders. The quantitative study and visualization of cell-to-cell propagation using tagged-proteins is challenging due to the steric effect of relatively large fluorescence tags and the risk of 'false positive...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00657-z
更新日期:2017-03-28 00:00:00
abstract::Phosphoinositides play important roles in numerous intracellular membrane pathways. Little is known about the regulation or function of these lipids in rod photoreceptor cells, which have highly active membrane dynamics. Using new assays with femtomole sensitivity, we determined that whereas levels of phosphatidylinos...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26978
更新日期:2016-06-01 00:00:00
abstract::We examine the spin-dependent manipulating of vector beams by tailoring the inhomogeneous polarization. The spin-dependent manipulating is attributed to the spin-dependent phase gradient in vector beams, which can be regarded as the intrinsic feature of inhomogeneous polarization. The desired polarization can be obtai...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34276
更新日期:2016-09-28 00:00:00
abstract::Competition between simultaneously presented visual stimuli lengthens reaction time and reduces both the BOLD response and neural firing. In contrast, conditions of sequential presentation have been assumed to be free from competition. Here we manipulated the spatial proximity of stimuli (Near versus Far conditions) t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05011-x
更新日期:2017-07-06 00:00:00
abstract::Mesenchymal stem cells (MSCs) have various functions, making a significant contribution to tissue repair. On the other hand, the viability and function of MSCs are not lasting after an in vivo transplant, and the therapeutic effects of MSCs are limited. Although various chemical modification methods have been applied ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17166-8
更新日期:2017-12-05 00:00:00
abstract::Two series of Ge0.8Sn0.2 samples were grown on Ge buffered Si substrate by molecular beam epitaxy (MBE) to investigate the influence of growth temperature and film thickness towards the evolution of surface morphology. A novel phenomena was observed that the Ge0.8Sn0.2 film was segregated and relaxed by the formation ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63152-y
更新日期:2020-04-09 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-59761-2
更新日期:2020-02-11 00:00:00
abstract::Intrasynovial tendon injuries are among the most challenging in orthopedics. Despite significant improvements in operative and rehabilitation methods, functional outcomes continue to be limited by adhesions, gap formation, and rupture. Adhesions result from excessive inflammation, whereas tendon gapping and rupture re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29474-8
更新日期:2018-07-23 00:00:00
abstract::A major translational challenge in the fields of therapeutic angiogenesis and regenerative medicine is the need to create functional microvasculature. The purpose of this study was to assess whether a potentially autologous endothelial cell (EC) source derived from human induced pluripotent stem cells (iPSC-ECs) can f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20966-1
更新日期:2018-02-08 00:00:00
abstract::Most traits of agricultural importance are quantitative traits controlled by numerous genes. However, it remains unclear about the molecular mechanisms underpinning quantitative traits. Here, we report the molecular characteristics of the genes controlling three quantitative traits randomly selected from three diverse...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66271-8
更新日期:2020-06-22 00:00:00
abstract::Karrikins (KAR) are a class of signal compounds, discovered in wildfire smoke, which affect seed germination. Currently, numerous studies have focused on the model plant Arabidopsis in the KAR research field, rather than on crops. Thus the regulatory mechanisms underlying KAR regulation of crop seed germination are la...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22073
更新日期:2016-02-23 00:00:00
abstract::Range-wide population studies of wide spread species are often associated with complex diversity patterns resulting from genetically divergent evolutionary significant units (ESUs). The compound evolutionary history creating such a pattern of diversity can be inferred through molecular analyses. Asparagus cochinchinen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46275-9
更新日期:2019-07-05 00:00:00
abstract::Faces presented upside-down are harder to recognize than presented right-side up, an effect known as the face inversion effect. With inversion the perceptual processing of the spatial relationship among facial parts is disrupted. Previous literature indicates a face inversion effect in chimpanzees toward familiar and ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02504
更新日期:2013-01-01 00:00:00
abstract::Anisotropically conductive materials are important components in subminiature devices. However, at this stage, some defects have limited practical applications of them, especially low anisotropic degree and high cost. Here, we report novel tricolor flag-liked microribbons array prepared by electrospinning technique. T...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep14583
更新日期:2015-09-28 00:00:00
abstract::Rare individuals remain cognitively intact despite the presence of neuropathology usually associated with fully symptomatic Alzheimer's disease (AD), which we refer to as Non-Demented with Alzheimer's disease Neuropathology (NDAN). Understanding the involved mechanism(s) of their cognitive resistance may reveal novel ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27812
更新日期:2016-06-14 00:00:00
abstract::Over the past few decades, two-dimensional (2D) and layered materials have emerged as new fields. Due to the zero-band-gap nature of graphene and the low photocatalytic performance of MoS2, more advanced semiconducting 2D materials have been prompted. As a result, semiconductor black phosphorus (BP) is a derived cutti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08691
更新日期:2015-03-03 00:00:00
abstract::Ceramide (Cer) release from glucosylceramides (GlcCer) is critical for the formation of the skin permeability barrier. Changes in β-glucocerebrosidase (GlcCer'ase) activity lead to diminished Cer, GlcCer accumulation and structural defects in SC lipid lamellae; however, the molecular basis for this impairment is not c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06990-7
更新日期:2017-07-25 00:00:00
abstract::Inhibition of immune checkpoint proteins like programmed death 1 (PD-1) is a promising therapeutic approach for several cancers, including non-small cell lung cancer (NSCLC). Although PD-1 ligand (PD-L1) expression is used to predict anti-PD-1 therapy responses in NSCLC, its accuracy is relatively less. Therefore, we ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65666-x
更新日期:2020-06-03 00:00:00
abstract::A number of studies have suggested that the irradiation behavior and damage processes occurring during sequential and simultaneous particle irradiations can significantly differ. Currently, there is no definite answer as to why and when such differences are seen. Additionally, the conventional multi-particle irradiati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30191
更新日期:2016-07-28 00:00:00
abstract::Electron ptychography has seen a recent surge of interest for phase sensitive imaging at atomic or near-atomic resolution. However, applications are so far mainly limited to radiation-hard samples, because the required doses are too high for imaging biological samples at high resolution. We propose the use of non-conv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07488-y
更新日期:2017-08-29 00:00:00
abstract::Human lactoferrin (hLF) is a valuable protein for pharmaceutical products and functional foods, and worldwide demand for this protein has steadily increased. However, large-scale recombinant human lactoferrin (rhLF) production using current animal bioreactor techniques is limited by the low expression of foreign prote...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-11462-z
更新日期:2017-09-06 00:00:00
abstract::Refractive surgical treatment of hyperopia still remains a challenge for refractive surgeons. A new nomogram of small incision lenticule extraction (SMILE) procedure has recently been developed for the treatment of hyperopia. In the present study, we aimed to evaluate the wound healing and inflammatory responses of th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29802
更新日期:2016-07-15 00:00:00
abstract::FTY720 is a sphingoid base analog that acts as an anticancer agent in animal models. Its effect on tumor cells stems largely from its ability to trigger endocytosis of several nutrient transporters. The observation that FTY720 similarly stimulates downregulation of amino acid permeases in yeast suggests that the cellu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14124-2
更新日期:2017-10-23 00:00:00
abstract::Combining endurance training with resistance training (RT) may attenuate skeletal muscle hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear. We investigated changes in markers of ribosome biogenesis, a process linked with skeletal muscle hypertrophy, following concurrent training v...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18887-6
更新日期:2018-01-12 00:00:00
abstract::Surface and soil core samples from northeast China were analyzed for Pu isotopes. The measured (240)Pu/(239)Pu atomic ratios and (239 + 240)Pu/(137)Cs activity ratios revealed that the global fallout is the dominant source of Pu and (137)Cs at these sites. Migration behavior of Pu varying with land type and human acti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03506
更新日期:2013-12-16 00:00:00
abstract::Nanoporous electrodes have received great attention because of their unique electrochemical properties. Here, the electrocatalytic oxygen evolution reaction (OER) activities at porous Pt layers with pore dimensions in the microporous range were examined. The OER activity of the porous Pt layers in acidic media increas...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-15688-9
更新日期:2017-11-13 00:00:00
abstract::Fully elucidating the molecular mechanisms of non-coding RNAs (ncRNAs), including micro RNAs (miRNAs) and long non-coding RNAs (lncRNAs), underlying hepatocarcinogenesis is challenging. We characterized the expression profiles of ncRNAs and constructed a regulatory mRNA-lncRNA-miRNA (MLMI) network based on transcripto...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52559-x
更新日期:2019-11-06 00:00:00
abstract::We recently showed that spinal cord injury (SCI) leads to a decrease in mRNA editing of serotonin receptor 2C (5-HT2CR) contributing to post-SCI spasticity. Here we study post-SCI mRNA editing and global gene expression using massively parallel sequencing. Evidence is presented that the decrease in 5-HT2CR editing is ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12615
更新日期:2015-07-30 00:00:00