Novel findings of the association between gut microbiota-derived metabolite trimethylamine N-oxide and inflammation: results from a systematic review and dose-response meta-analysis.

Abstract:

:The gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) has been regarded as one of the potent risk factors of cardiovascular events and diabetes. However, its association with possible inflammatory mediators has not been revealed yet. In the current meta-analysis, we quantitatively summarized the results of studies regarding the association between TMAO and inflammation. Electronic databases including PubMed, ProQuest, Scopus, and Embase were systematically searched and a total of 586 manuscripts were retrieved. After removing 223 duplicates, 363 manuscripts were reviewed. All of the studies regarding the association between TMAO and inflammatory factors were included in the systematic review and eligible studies were included in to the meta-analysis. Accordingly, 13,783 number of participants were included and the results showed that being in the highest category of TMAO Accordingly was associated with 0.27 mg/L (weighted mean difference: 0.268; 95% confidence interval [CI]: 0.058-0.479; p = 0.013) increase in CRP concentrations compared with lowest category. The results of subgrouping and meta-regression revealed the location, CRP sample source, disease status, male percent, proportion of diabetes and smoking as the source of heterogeneity. Moreover, the dose-response meta-analysis revealed a non-linear association between increased TMAO concentrations and increased CRP concentrations (p for nonlinearity = 0.015). To our knowledge, this is first dose-response meta-analysis that summarized the results of studies about the association between circulating TMAO concentrations and inflammation risk.

journal_name

Crit Rev Food Sci Nutr

authors

Farhangi MA,Vajdi M

doi

10.1080/10408398.2020.1770199

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

2801-2823

issue

16

eissn

1040-8398

issn

1549-7852

journal_volume

60

pub_type

杂志文章,meta分析
  • Review of the quantification techniques for polycyclic aromatic hydrocarbons (PAHs) in food products.

    abstract::There is a growing need for accurate detection of trace-level PAHs in food products due to the numerous detrimental effects caused by their contamination (e.g., toxicity, carcinogenicity, and teratogenicity). This review aims to discuss the up-to-date knowledge on the measurement techniques available for PAHs containe...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2015.1116970

    authors: Bansal V,Kumar P,Kwon EE,Kim KH

    更新日期:2017-10-13 00:00:00

  • Association between vitamin deficiency and metabolic disorders related to obesity.

    abstract::Inappropriate food behavior contributes to obesity and leads to vitamin deficiency. This review discusses the nutritional status of water- and fat-soluble vitamins in obese subjects. We verified that most vitamins are deficient in obese individuals, especially the fat-soluble vitamins, folic acid, vitamin B12 and vita...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2015.1117413

    authors: Thomas-Valdés S,Tostes MDGV,Anunciação PC,da Silva BP,Sant'Ana HMP

    更新日期:2017-10-13 00:00:00

  • Biochemistry and technology of chickpea (Cicer arietinum L.) seeds.

    abstract::Chickpea is an important source of proteins, carbohydrates, B-group vitamins, and certain minerals, particularly to the populations of developing nations. India contributes over 75% of the chickpea production in the world where it is mostly consumed as dhal, whole seeds, and several types of traditional, fermented, de...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398709527449

    authors: Chavan JK,Kadam SS,Salunkhe DK

    更新日期:1986-01-01 00:00:00

  • The influence of omega-3 supplementation on vitamin D levels in humans: a systematic review and dose-response meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Inconsistencies exist with regard to the influence of omega-3 supplementation on 25-hydroxyvitamin D (25(OH)D) levels, which could be attributed to many factors, such as the duration and dose of omega-3 supplementation, and individuals' baseline 25(OH)D levels. Therefore, to address the inconsistencies, we c...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1863905

    authors: Alhabeeb H,Kord-Varkaneh H,Tan SC,Găman MA,Otayf BY,Qadri AA,Alomar O,Salem H,Al-Badawi IA,Abu-Zaid A

    更新日期:2020-12-25 00:00:00

  • Effective regulatory approval process for food ingredient technologies.

    abstract::Most sciences and technologies related to food safety have advanced exponentially over the 40 years since passage in the U.S. of the Food Additive Amendment of 1958 to the Federal Food, Drug and Cosmetic (FD&C) Act. Effective regulatory decision making places a high premium on competent professional and administrative...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408699891274282

    authors: Kirschman JC

    更新日期:1998-08-01 00:00:00

  • 3D printing of food: pretreatment and post-treatment of materials.

    abstract:BACKGROUND:Food 3 D printing is an emerging food processing technology. Due to the advantages of functionalization, customization, personalized nutrition design, simplified supply chain and broadening existing food materials, 3 D printing has been extensively studied in the food sector in the past decade. Many factors ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2019.1641065

    authors: He C,Zhang M,Fang Z

    更新日期:2020-01-01 00:00:00

  • An overview on chemical aspects and potential health benefits of limonoids and their derivatives.

    abstract::Limonoids are heavily oxygenated, modified triterpenes dominant in Meliaceae and Rutaceae plant families. The term 'limonoid' is derived from limonin, which was first identified as the bitter constituent of Citrus seeds in 1841. This group of secondary metabolites exhibits a wide range of biological properties, includ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.581400

    authors: Tundis R,Loizzo MR,Menichini F

    更新日期:2014-01-01 00:00:00

  • Plant proteases for bioactive peptides release: A review.

    abstract::Proteins are a potential source of health-promoting biomolecules with medical, nutraceutical, and food applications. Nowadays, bioactive peptides production, its isolation, characterization, and strategies for its delivery to target sites are a matter of intensive research. In vitro and in vivo studies regarding the b...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2017.1308312

    authors: Mazorra-Manzano MA,Ramírez-Suarez JC,Yada RY

    更新日期:2018-01-01 00:00:00

  • A comprehensive review on the nanocomposites loaded with chitosan nanoparticles for food packaging.

    abstract::Chitosan is mainly derived from seafood by-products and the thereof chitosan nanoparticles (CNPs) are known as nontoxic, biocompatible, biodegradable and functionalized nanostructures. CNPs, as green fillers, showed an appropriate potential in reinforcement of various biodegradable composites for food packaging and bi...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1843133

    authors: Garavand F,Cacciotti I,Vahedikia N,Rehman A,Tarhan Ö,Akbari-Alavijeh S,Shaddel R,Rashidinejad A,Nejatian M,Jafarzadeh S,Azizi-Lalabadi M,Khoshnoudi-Nia S,Jafari SM

    更新日期:2020-11-05 00:00:00

  • Low-alcohol Beers: Flavor Compounds, Defects, and Improvement Strategies.

    abstract::Beer consumers are accustomed to a product that offers a pleasant and well-defined taste. However, in alcohol-free and alcohol-reduced beers these characteristics are totally different from those in regular beer. Therefore, it is important to evaluate and determine the different flavor compounds that affect organolept...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2012.733979

    authors: Blanco CA,Andrés-Iglesias C,Montero O

    更新日期:2016-06-10 00:00:00

  • Rice bran: a novel functional ingredient.

    abstract::Rice (Oryza sativa) is the most important staple food for a large part of the world's human population, especially in East and South Asia, the Middle East, Latin America, and the West Indies. It provides more than one fifth of the calories consumed worldwide by the human. It is the second leading cereal crop and stapl...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.608586

    authors: Sharif MK,Butt MS,Anjum FM,Khan SH

    更新日期:2014-01-01 00:00:00

  • FDA's public health goals in evaluating health claims.

    abstract::Scientific developments have increased awareness of possible links between diet and health within the scientific community and in the general public and have generated interest in the use of disease-related health claims on food labels. The enactment of the Nutrition, Labeling, and Education Act for the first time aut...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408399509527681

    authors: Taylor MR

    更新日期:1995-01-01 00:00:00

  • Microporous modified atmosphere packaging to extend shelf life of fresh foods: A review.

    abstract::In recent years, microporous modified atmosphere packaging has been widely concerned because of its adjustable air permeability and low processing cost. With the development and increasing demand of fresh food industry, the limited permeability of film in modified atmosphere packaging can't meet the fresh-keeping requ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1811635

    authors: Qu P,Zhang M,Fan K,Guo Z

    更新日期:2020-08-28 00:00:00

  • Using power ultrasound to accelerate food freezing processes: Effects on freezing efficiency and food microstructure.

    abstract::Freezing is an effective way of food preservation. However, traditional freezing methods have the disadvantages of low freezing efficiency and generation of large ice crystals, leading to possible damage of food quality. Power ultrasound assisted freezing as a novel technique can effectively reduce the adverse effects...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2018.1482528

    authors: Zhang P,Zhu Z,Sun DW

    更新日期:2018-01-01 00:00:00

  • Regulating the use of degraded oil/fat in deep-fat/oil food frying.

    abstract::During frying, the degradation of oil produces harmful compounds. Improper monitoring of oil-discard times in restaurants either risks the public health or causes financial losses to industries. Measuring the oil quality is a complex problem and an online sensor is needed. The process of frying reviewed includes moist...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408399709527793

    authors: Paul S,Mittal GS

    更新日期:1997-11-01 00:00:00

  • Enhancing production of microalgal biopigments through metabolic and genetic engineering.

    abstract::The versatile use of biopigments in food, feed, cosmetic, pharmaceutical and analytical industries emphasized to find different and renewable sources of biopigments. Microalgae, including cyanobacteria, are becoming a potential candidate for pigment production as these have fast-growing ability, high pigment content, ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2018.1533518

    authors: Saini DK,Chakdar H,Pabbi S,Shukla P

    更新日期:2020-01-01 00:00:00

  • Impact of gut microbiota on neurological diseases: Diet composition and novel treatments.

    abstract::Gut microbiota has significant effects on the structure and function of the enteric and central nervous system including human behaviour and brain regulation. Herein, we analyze the role of this intestinal ecosystem, the effects of dietary changes and the administration of nutritional supplements, such as probiotics, ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2018.1484340

    authors: Larroya-García A,Navas-Carrillo D,Orenes-Piñero E

    更新日期:2019-01-01 00:00:00

  • The role of antioxidants in gastric carcinogenesis.

    abstract::The epidemiologic evidence for a role of antioxidants in inhibiting carcinogenesis in humans is briefly summarized. Mechanistic pathways of protection by antioxidants are illustrated with the prevailing model of gastric carcinogenesis in humans. In this model, ascorbic acid may be involved at the early stage of chroni...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408399509527687

    authors: Correa P

    更新日期:1995-01-01 00:00:00

  • An overview of the effect of probiotics and exercise on mood and associated health conditions.

    abstract::The present paper provides a review of the current knowledge relating to the health benefits of probiotics, specially focused on the effects they may have together with physical exercise on mood disorders and related chronic medical conditions.With both these conditions being a substantial contributor to the global di...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2016.1189872

    authors: Grant MC,Baker JS

    更新日期:2017-12-12 00:00:00

  • The relationship between iron status and adiposity in women from developing countries: a review.

    abstract::Scientific reports have shown that iron deficiency is positively associated with adiposity. With the high prevalence of iron deficiency and obesity in developing countries and women being particularly affected, this review was carried out with the aim of elucidating the link between iron status and adiposity in women ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.594914

    authors: Aderibigbe OR,Pisa PT,Vorster HH,Kruger SH

    更新日期:2014-01-01 00:00:00

  • Application of hyperspectral imaging in food safety inspection and control: a review.

    abstract::Food safety is a great public concern, and outbreaks of food-borne illnesses can lead to disturbance to the society. Consequently, fast and nondestructive methods are required for sensing the safety situation of produce. As an emerging technology, hyperspectral imaging has been successfully employed in food safety ins...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.651542

    authors: Feng YZ,Sun DW

    更新日期:2012-01-01 00:00:00

  • Bioactive lipids in pathological retinopathy.

    abstract::Diabetic retinopathy is a common condition that occurs in patients with diabetes with long-standing hyperglycemia that is characterized by inappropriate angiogenesis. This pathological angiogenesis could be a sort of physiological proliferative response to injury by the endothelium. Recent studies suggested that react...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.565523

    authors: Ma Q,Shen JH,Shen SR,Das UN

    更新日期:2014-01-01 00:00:00

  • Viscosity as related to dietary fiber: a review.

    abstract::Viscosity is a physicochemical property associated with dietary fibers, particularly soluble dietary fibers. Viscous dietary fibers thicken when mixed with fluids and include polysaccharides such as gums, pectins, psyllium, and beta-glucans. Although insoluble fiber particles may affect viscosity measurement, viscosit...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408390500511862

    authors: Dikeman CL,Fahey GC

    更新日期:2006-01-01 00:00:00

  • Global occurrence of deoxynivalenol in food commodities and exposure risk assessment in humans in the last decade: a survey.

    abstract::Preventing food from fungal infestation has become a cause of great concern as food safety is of particular importance to public health globally. Recently International Agency for Research on Cancer (IARC) and the World Health Organization (WHO) in its 2016 press release has urged to take action against widespread myc...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2019.1571479

    authors: Mishra S,Srivastava S,Dewangan J,Divakar A,Kumar Rath S

    更新日期:2020-01-01 00:00:00

  • Synthesis of novel α-glucans with potential health benefits through controlled glucose release in the human gastrointestinal tract.

    abstract::The glycemic carbohydrates we consume are currently viewed in an unfavorable light in both the consumer and medical research worlds. In significant part, these carbohydrates, mainly starch and sucrose, are looked upon negatively due to their rapid and abrupt glucose delivery to the body which causes a high glycemic re...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2018.1516621

    authors: Gangoiti J,Corwin SF,Lamothe LM,Vafiadi C,Hamaker BR,Dijkhuizen L

    更新日期:2020-01-01 00:00:00

  • Black pepper and health claims: a comprehensive treatise.

    abstract::For millennia, spices have been an integral part of human diets and commerce. Recently, the widespread recognition of diet-health linkages bolsters their dietary importance. The bioactive components present in them are of considerable significance owing to their therapeutic potential against various ailments. They pro...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.571799

    authors: Butt MS,Pasha I,Sultan MT,Randhawa MA,Saeed F,Ahmed W

    更新日期:2013-01-01 00:00:00

  • Spray-drying wall materials: relationship with bioactive compounds.

    abstract::The encapsulation by spray drying is a common method of encapsulation on the food industry. Many biopolymers are described on the literature as wall materials for this purpose. As different wall materials are applied on spray drying, it is necessary to know their physicochemical characteristics. In view of the differe...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1786354

    authors: Coimbra PPS,Cardoso FSN,Gonçalves ÉCBA

    更新日期:2020-07-02 00:00:00

  • Current and future perspectives for controlling Vibrio biofilms in the seafood industry: a comprehensive review.

    abstract::The contamination of seafood with Vibrio species can have severe repercussions in the seafood industry. Vibrio species can form mature biofilms and persist on the surface of several seafoods such as crabs, oysters, mussels, and shrimp, for extended duration. Several conventional approaches have been employed to inhibi...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1767031

    authors: Ashrafudoulla M,Mizan MFR,Park SH,Ha SD

    更新日期:2020-05-21 00:00:00

  • Carotene Degradation and Isomerization during Thermal Processing: A Review on the Kinetic Aspects.

    abstract::Kinetic models are important tools for process design and optimization to balance desired and undesired reactions taking place in complex food systems during food processing and preservation. This review covers the state of the art on kinetic models available to describe heat-induced conversion of carotenoids, in part...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2013.790779

    authors: Colle IJ,Lemmens L,Knockaert G,Van Loey A,Hendrickx M

    更新日期:2016-08-17 00:00:00

  • Nutrition and health – transforming research traditions.

    abstract::In this contribution, we show that current scientific methodologies used in nutrition science and by regulatory agencies, such as the randomized control trial, limit our understanding of nutrition and health as they are to crude to capture the subtle pleiotropic nature of most nutrients. Thereby, regulatory agencies s...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2012.680525

    authors: Hanekamp JC,Bast A,Calabrese EJ

    更新日期:2015-01-01 00:00:00