Nutrition and health – transforming research traditions.

Abstract:

:In this contribution, we show that current scientific methodologies used in nutrition science and by regulatory agencies, such as the randomized control trial, limit our understanding of nutrition and health as they are to crude to capture the subtle pleiotropic nature of most nutrients. Thereby, regulatory agencies such as the European Food Safety Authority curb the development of scientific knowledge and industrial innovations within the nutritional field. In order to develop insights into the health impact of certain food and food-components, we need to realize that health is adaptation set within a homeostatic range. Increased performance of health, i.e., the maximum stimulation of health, typically seems 30-60% greater than the control group, with a width of no more than about a factor of ten, clarifying the difficulty of documenting responses of food-endogenous components within the homeostatic range of healthy people. A strategy to record subtle responses of food components is the summation of procentual effects of relevant health outcomes. We illustrate this approach with the action of flavanols on vascular health, specifically endothelial function.

journal_name

Crit Rev Food Sci Nutr

authors

Hanekamp JC,Bast A,Calabrese EJ

doi

10.1080/10408398.2012.680525

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

1074-80

issue

8

eissn

1040-8398

issn

1549-7852

journal_volume

55

pub_type

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