An overview on chemical aspects and potential health benefits of limonoids and their derivatives.

Abstract:

:Limonoids are heavily oxygenated, modified triterpenes dominant in Meliaceae and Rutaceae plant families. The term 'limonoid' is derived from limonin, which was first identified as the bitter constituent of Citrus seeds in 1841. This group of secondary metabolites exhibits a wide range of biological properties, including anticancer, antibacterial, antifungal, antimalarial, and antiviral activities. Significant progress on the role of limonoids as promising candidates for cancer chemoprevention and/or therapy has been achieved in particular in recent years. The aim of this review article is to discuss the recent developments on limonoids chemical aspects and biological activities with the relationship between structure and activity, supporting the new possibilities for the medicinal and/or nutraceutical use of these compounds.

journal_name

Crit Rev Food Sci Nutr

authors

Tundis R,Loizzo MR,Menichini F

doi

10.1080/10408398.2011.581400

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

225-50

issue

2

eissn

1040-8398

issn

1549-7852

journal_volume

54

pub_type

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