Riboflavin and health: A review of recent human research.

Abstract:

:There has lately been a renewed interest in Riboflavin owing to insight into its recognition as an essential component of cellular biochemistry. The knowledge of the mechanisms and regulation of intestinal absorption of riboflavin and its health implications has significantly been expanded in recent years. The purpose of this review is to provide an overview of the importance of riboflavin, its absorption and metabolism in health and diseased conditions, its deficiency and its association with various health diseases, and metabolic disorders. Efforts have been made to review the available information in literature on the relationship between riboflavin and various clinical abnormalities. The role of riboflavin has also been dealt in the prevention of a wide array of health diseases like migraine, anemia, cancer, hyperglycemia, hypertension, diabetes mellitus, and oxidative stress directly or indirectly. The riboflavin deficiency has profound effect on iron absorption, metabolism of tryptophan, mitochondrial dysfunction, gastrointestinal tract, brain dysfunction, and metabolism of other vitamins as well as is associated with skin disorders. Toxicological and photosensitizing properties of riboflavin make it suitable for biological use, such as virus inactivation, excellent photosensitizer, and promising adjuvant in chemo radiotherapy in cancer treatment. A number of recent studies have indicated and highlighted the cellular processes and biological effects associated with riboflavin supplementation in metabolic diseases. Overall, a deeper understanding of these emerging roles of riboflavin intake is essential to design better therapies for future.

journal_name

Crit Rev Food Sci Nutr

authors

Thakur K,Tomar SK,Singh AK,Mandal S,Arora S

doi

10.1080/10408398.2016.1145104

subject

Has Abstract

pub_date

2017-11-22 00:00:00

pages

3650-3660

issue

17

eissn

1040-8398

issn

1549-7852

journal_volume

57

pub_type

杂志文章,评审
  • Acute effects of dietary plant nutrients on transcriptome profiles: evidence from human studies.

    abstract::The health benefits of long-term dietary plant ingestion are well-established. However, literature on acute nutritional challenges is very limited. This study aimed to identify available evidence on transcriptomics responses to acute ingestion of plants or plant extracts and identify signature gene profiles that may s...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2019.1608154

    authors: Jamshidi N,Mantri N,Cohen MM

    更新日期:2020-01-01 00:00:00

  • Lycopene in tomatoes: chemical and physical properties affected by food processing.

    abstract::Lycopene is the pigment principally responsible for the characteristic deep-red color of ripe tomato fruits and tomato products. It has attracted attention due to its biological and physicochemical properties, especially related to its effects as a natural antioxidant. Although it has no provitamin A activity, lycopen...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408690091189275

    authors: Shi J,Le Maguer M

    更新日期:2000-01-01 00:00:00

  • Targeting NF-κB signaling pathway in cancer by dietary polyphenols.

    abstract::Being a transcription factor, NF-κB regulates gene expressions involving cell survival and proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a central role in the development of inflammation and cancer. Thus, the down-regulation of NF-κB may be an exciting target in prevention...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2019.1661827

    authors: Khan H,Ullah H,Castilho PCMF,Gomila AS,D'Onofrio G,Filosa R,Wang F,Nabavi SM,Daglia M,Silva AS,Rengasamy KRR,Ou J,Zou X,Xiao J,Cao H

    更新日期:2020-01-01 00:00:00

  • An overview on chemical aspects and potential health benefits of limonoids and their derivatives.

    abstract::Limonoids are heavily oxygenated, modified triterpenes dominant in Meliaceae and Rutaceae plant families. The term 'limonoid' is derived from limonin, which was first identified as the bitter constituent of Citrus seeds in 1841. This group of secondary metabolites exhibits a wide range of biological properties, includ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.581400

    authors: Tundis R,Loizzo MR,Menichini F

    更新日期:2014-01-01 00:00:00

  • Whey protein concentrates and isolates: processing and functional properties.

    abstract::Substantial progress has been made in understanding the basic chemical and structural properties of the principal whey proteins, that is, beta-lactoglobulin (beta-Lg), alpha-lactalbumin (alpha-La), bovine serum albumin (BSA), and immunoglobulin (Ig). This knowledge has been acquired in terms of: (1) procedures for iso...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408399309527643

    authors: Morr CV,Ha EY

    更新日期:1993-01-01 00:00:00

  • Effect of Hurdle Technology in Food Preservation: A Review.

    abstract::Hurdle technology is used in industrialized as well as in developing countries for the gentle but effective preservation of foods. Hurdle technology was developed several years ago as a new concept for the production of safe, stable, nutritious, tasty, and economical foods. Previously hurdle technology, i.e., a combin...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2012.761594

    authors: Singh S,Shalini R

    更新日期:2016-01-01 00:00:00

  • Thermal pasteurization of ready-to-eat foods and vegetables: Critical factors for process design and effects on quality.

    abstract::Increasing consumer desire for high quality ready-to-eat foods makes thermal pasteurization important to both food producers and researchers. To be in compliance with the Food Safety Modernization Act (FSMA), food companies seek regulatory and scientific guidelines to ensure that their products are safe. Clearly under...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2015.1082126

    authors: Peng J,Tang J,Barrett DM,Sablani SS,Anderson N,Powers JR

    更新日期:2017-09-22 00:00:00

  • An overview of the effect of probiotics and exercise on mood and associated health conditions.

    abstract::The present paper provides a review of the current knowledge relating to the health benefits of probiotics, specially focused on the effects they may have together with physical exercise on mood disorders and related chronic medical conditions.With both these conditions being a substantial contributor to the global di...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2016.1189872

    authors: Grant MC,Baker JS

    更新日期:2017-12-12 00:00:00

  • Bioactive lipids in pathological retinopathy.

    abstract::Diabetic retinopathy is a common condition that occurs in patients with diabetes with long-standing hyperglycemia that is characterized by inappropriate angiogenesis. This pathological angiogenesis could be a sort of physiological proliferative response to injury by the endothelium. Recent studies suggested that react...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.565523

    authors: Ma Q,Shen JH,Shen SR,Das UN

    更新日期:2014-01-01 00:00:00

  • Towards a dietary-exposome assessment of chemicals in food: An update on the chronic health risks for the European consumer.

    abstract::An informed opinion to a hugely important question, whether the food on the Europeans' plate is safe to eat, is provided. Today, the Europeans face food-borne health risks from non-communicable diseases induced by excess body weight, outbreaks caused by pathogens, antimicrobial resistance and exposures to chemical con...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2019.1612320

    authors: Eskola M,Elliott CT,Hajšlová J,Steiner D,Krska R

    更新日期:2020-01-01 00:00:00

  • Nutrition, endothelial cell metabolism, and atherosclerosis.

    abstract::The vascular endothelium that forms an interface between the blood and the surrounding tissues is continuously exposed to both physiologic and pathophysiologic stimuli. These stimuli are often mediated by nutrients that can contribute to the overall function of the endothelial cell in the regulation of vascular tone, ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408399409527663

    authors: Hennig B,Toborek M,Cader AA,Decker EA

    更新日期:1994-01-01 00:00:00

  • A review on the aroma composition of Vitis vinifera L. Pinot noir wines: origins and influencing factors.

    abstract::Vitis vinifera L. Pinot noir still wines are some of the most popular and expensive red wines in the world. Several research articles are reported in literature concerning the impacts of viticultural and enological practices, and vineyard location, on Pinot noir still wine aroma. This review summarizes the previous an...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1762535

    authors: Longo R,Carew A,Sawyer S,Kemp B,Kerslake F

    更新日期:2020-05-13 00:00:00

  • Dietary polyphenols and chromatin remodeling.

    abstract::Polyphenols are the most abundant phytochemicals in fruits, vegetables, and plant-derived beverages. Recent findings suggest that polyphenols display the ability to reverse adverse epigenetic regulation involved in pathological conditions, such as obesity, metabolic disorder, cardiovascular and neurodegenerative disea...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2015.1062353

    authors: Russo GL,Vastolo V,Ciccarelli M,Albano L,Macchia PE,Ungaro P

    更新日期:2017-08-13 00:00:00

  • Advances in dietary enrichment with n-3 fatty acids.

    abstract::Evidence for the effectiveness of the enrichment of food products with n-3 fatty acids by inclusion of either plant- or fish-derived materials in the diets of chickens, turkeys, ostriches, cows, pigs, and goats has been reviewed. Both linseed oil/meal and fish products can increase the levels of total n-3 fatty acids ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408390701424303

    authors: Moghadasian MH

    更新日期:2008-05-01 00:00:00

  • A review of the role of inositols in conditions of insulin dysregulation and in uncomplicated and pathological pregnancy.

    abstract::Inositols, a group of 6-carbon polyols, are highly bioactive molecules derived from diet and endogenous synthesis. Inositols and their derivatives are involved in glucose and lipid metabolism and participate in insulin-signaling, with perturbations in inositol processing being associated with conditions involving insu...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1845604

    authors: Watkins OC,Yong HEJ,Sharma N,Chan SY

    更新日期:2020-12-07 00:00:00

  • A new look at early exposure to the flavors of the available vegetables as foundational mechanism of vegetable consumption habits and recipes of vegetables-based dishes.

    abstract::The flavor of the maternal diet is transferred to women's amniotic fluid and breast milk, so that the amniotic fluid and breast milk become natural transmitters of flavor-related information developing babies are exposed to at early stages of development. We aimed to review the available evidence regarding the impact ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1747047

    authors: Domínguez PR

    更新日期:2020-04-08 00:00:00

  • Effect of drying methods and storage with agro-ecological conditions on phytochemicals and antioxidant activity of fruits: a review.

    abstract::Choice of drying methods significantly impacts the nutritive and non-nutritive compounds in fruits and vegetables. Phytochemicals such as total phenolics and total flavonoids are non-nutritive bioactive compounds and are found in plants which are of important value due to their antioxidant properties in minimizing the...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2020.1816891

    authors: Vidinamo F,Fawzia S,Karim MA

    更新日期:2020-09-10 00:00:00

  • Processing effects for safety and quality in some non-predominant food technologies.

    abstract::Food functionality can be related to nutrient and non-nutrient compounds. Some foods are fortified with various nutrients whereas others are manipulated using their physicochemical properties in order to make them "functional." Texture, color, taste, odor, and other physicochemical properties may affect the overall qu...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408390600626560

    authors: Ortega-Rivas E

    更新日期:2007-01-01 00:00:00

  • Understanding critical factors for the quality and shelf-life of MAP fresh meat: a review.

    abstract::Due to increased demands for greater stringency in relation to hygiene and safety issues associated with fresh food products, coupled with ever-increasing demands by retailers for cost-effective extensions to product shelf-lives and the requirement to meet consumer expectations in relation to convenience and quality, ...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408390903531384

    authors: Singh P,Wani AA,Saengerlaub S,Langowski HC

    更新日期:2011-02-01 00:00:00

  • Effect of tea and other dietary factors on iron absorption.

    abstract::Iron deficiency is a major world health problem, that is, to a great extent, caused by poor iron absorption from the diet. Several dietary factors can influence this absorption. Absorption enhancing factors are ascorbic acid and meat, fish and poultry; inhibiting factors are plant components in vegetables, tea and cof...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408690091189194

    authors: Zijp IM,Korver O,Tijburg LB

    更新日期:2000-09-01 00:00:00

  • The mouthfeel of white wine.

    abstract::White wine mouthfeel which encompasses the tactile, chemosensory and taste attributes of perceived viscosity, astringency, hotness and bitterness is increasingly being recognized as an important component of overall white wine quality. This review summarizes the physiological basis for the perception of white wine mou...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2017.1346584

    authors: Gawel R,Smith PA,Cicerale S,Keast R

    更新日期:2018-01-01 00:00:00

  • Potato consumption and risk of all cause, cancer and cardiovascular mortality: a systematic review and dose-response meta-analysis of prospective cohort studies.

    abstract::A systematic review and meta-analysis of prospective cohort studies was conducted to examine the association of potato consumption and risk of all-cause, cancer and cardiovascular mortality in adults. We searched PubMed, Scopus databases up to September 2018 for all relevant published papers. All analyses were perform...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,meta分析

    doi:10.1080/10408398.2018.1557102

    authors: Darooghegi Mofrad M,Milajerdi A,Sheikhi A,Azadbakht L

    更新日期:2020-01-01 00:00:00

  • Nanotech: propensity in foods and bioactives.

    abstract::Nanotechnology is seeing higher propensity in various industries, including food and bioactives. New nanomaterials are constantly being developed from both natural biodegradable polymers of plant and animal origins such as polysaccharides and derivatives, peptides and proteins, lipids and fats, and biocompatible synth...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2010.494259

    authors: Kuan CY,Yee-Fung W,Yuen KH,Liong MT

    更新日期:2012-01-01 00:00:00

  • (Electro)Sensing of Phenicol Antibiotics-A Review.

    abstract::The presence of residues from frequent antibiotic use in animal feed can cause serious health risks by contaminating products meant for human consumption such as meat and milk. The present paper gives an overview of the electrochemical methods developed for the detection of phenicol antibiotic residues (chloramphenico...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2013.845140

    authors: Pilehvar S,Gielkens K,Trashin SA,Dardenne F,Blust R,De Wael K

    更新日期:2016-10-25 00:00:00

  • Recently isolated antidiabetic hydrolysates and peptides from multiple food sources: a review.

    abstract::Diabetes, a metabolic syndrome of global importance has been on a progressive rise in recent years. Several pharmacological approaches have been made, which have proved effective, but with underlying side effects. Bioactive hydrolysates (BHs) and peptides (BPs) from food sources, however, have shown the relative advan...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2018.1528206

    authors: Kehinde BA,Sharma P

    更新日期:2020-01-01 00:00:00

  • Cocoa phytochemicals: recent advances in molecular mechanisms on health.

    abstract::Recent reports on cocoa are appealing in that a food commonly consumed for pure pleasure might also bring tangible benefits for human health. Cocoa consumption is correlated with reduced health risks of cardiovascular diseases, hypertension, atherosclerosis, and cancer, and the health-promoting effects of cocoa are me...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2011.641041

    authors: Kim J,Kim J,Shim J,Lee CY,Lee KW,Lee HJ

    更新日期:2014-01-01 00:00:00

  • Plant compounds for the potential reduction of food waste - a focus on antimicrobial peptides.

    abstract::A large portion of global food waste is caused by microbial spoilage. The modern approach to preserve food is to apply different hurdles for microbial pathogens to overcome. These vary from thermal processes and chemical additives, to the application of irradiation and modified atmosphere packaging. Even though such p...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章

    doi:10.1080/10408398.2021.1873733

    authors: Shwaiki LN,Arendt EK,Lynch KM

    更新日期:2021-01-22 00:00:00

  • Low-alcohol Beers: Flavor Compounds, Defects, and Improvement Strategies.

    abstract::Beer consumers are accustomed to a product that offers a pleasant and well-defined taste. However, in alcohol-free and alcohol-reduced beers these characteristics are totally different from those in regular beer. Therefore, it is important to evaluate and determine the different flavor compounds that affect organolept...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2012.733979

    authors: Blanco CA,Andrés-Iglesias C,Montero O

    更新日期:2016-06-10 00:00:00

  • Nutritional status and follicular-derived thyroid cancer: An update.

    abstract::The incidence of differentiated thyroid cancer has been increasing in the last decades all over the world. Such a steady growth cannot be entirely attributable to more intensive thyroid nodule screening and more sensitive diagnostic procedures. Several environmental factors have changed with sufficient rapidity in the...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2020.1714542

    authors: Barrea L,Gallo M,Ruggeri RM,Giacinto PD,Sesti F,Prinzi N,Adinolfi V,Barucca V,Renzelli V,Muscogiuri G,Colao A,Baldelli R,E.O.L.O. Group.

    更新日期:2021-01-01 00:00:00

  • Recent advancements in the application of non-thermal plasma technology for the seafood industry.

    abstract::Non-thermal plasma (NTP) is one of the most promising minimal processing methods for the food industry. However up until recently there are limited studies which would report the application and effect of NTP on processed seafood. The objective of this review is to highlight the recent findings and advancements in the...

    journal_title:Critical reviews in food science and nutrition

    pub_type: 杂志文章,评审

    doi:10.1080/10408398.2018.1510827

    authors: Kulawik P,Kumar Tiwari B

    更新日期:2019-01-01 00:00:00