Abstract：
:Bisphenol A (BPA) is a widespread pollutant threatening the ecosystem and human health. An effective BPA degrader YC-JY1 was isolated and identified as Sphingobium sp. The optimal temperature and pH for the degradation of BPA by strain YC-JY1 were 30 °C and 6.5, respectively. The biodegradation pathway was proposed based on the identification of the metabolites. The addition of cytochrome P450 (CYP) inhibitor 1-aminobenzotriazole significantly decreased the degradation of BPA by Sphingobium sp. YC-JY1. Escherichia coli BL21 (DE3) cells harboring pET28a-bisdAB achieved the ability to degrade BPA. The bisdB gene knockout strain YC-JY1ΔbisdB was unable to degrade BPA indicating that P450 bisdB was an essential initiator of BPA metabolism in strain YC-JY1. For BPA polluted soil remediation, strain YC-JY1 considerably stimulated biodegradation of BPA associated with the soil microbial community. These results point out that strain YC-JY1 is a promising microbe for BPA removal and possesses great application potential.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Jia Y,Eltoukhy A,Wang J,Li X,Hlaing TS,Aung MM,Nwe MT,Lamraoui I,Yan Ydoi
10.3390/ijms21103588subject
Has Abstractpub_date
2020-05-19 00:00:00issue
10issn
1422-0067pii
ijms21103588journal_volume
21pub_type
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