Regulatory Role of MicroRNAs in Muscle Atrophy during Exercise Intervention.

Abstract:

:Skeletal muscle comprising approximately 40% of body weight is highly important for locomotion and metabolic homeostasis. The growth and regeneration of skeletal muscle are highly organized processes; thus, it is not surprising to reveal certain complexity during these regulatory processes. Recently, a large number of evidence indicate that microRNAs can result in obvious impacts on growth, regeneration and metabolism of skeletal muscle. In this review, recent research achievements of microRNAs in regulating myogenesis, atrophy and aging during exercise intervention are discussed, which will provide the guidance for developing potential applications of microRNAs in health promotion and rehabilitation of sports injuries.

journal_name

Int J Mol Sci

authors

Zhang S,Chen N

doi

10.3390/ijms19020405

subject

Has Abstract

pub_date

2018-01-30 00:00:00

issue

2

issn

1422-0067

pii

ijms19020405

journal_volume

19

pub_type

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