当前位置： SCI文献检索 > Journal of Global Antimicrobial Resistance期刊下所有文献 > Genetic diversity and in vitro activity of ceftazidime/avibactam and aztreonam/avibactam against imipenem-resistant Enterobacteriaceae isolates in Southwest China: A single-centre study.

Genetic diversity and in vitro activity of ceftazidime/avibactam and aztreonam/avibactam against imipenem-resistant Enterobacteriaceae isolates in Southwest China: A single-centre study.

Abstract：

OBJECTIVES:The aim of this study was to investigate the molecular mechanisms of imipenem resistance in Enterobacteriaceae and to assess the antimicrobial activities of ceftazidime/avibactam (CAZ/AVI) and aztreonam/avibactam (ATM/AVI) against imipenem-resistant clinical isolates in a tertiary hospital in China. METHODS:A total of 91 imipenem-resistant Enterobacteriaceae were collected and genes encoding carbapenemases, ESBLs, AmpC β-lactamases and porins were detected using PCR. MICs and susceptibility were determined using in-house-prepared broth microdilution panels and were interpreted according to CLSI breakpoints. RESULTS:Imipenem-resistant isolates comprising 54 Klebsiella pneumoniae, 18 Escherichia coli, 8 Enterobacter cloacae, 6 Serratia marcescens, 3 Klebsiella oxytoca and 2 Klebsiella aerogenes were collected independently. Five different carbapenemase genes were identified, namely blaKPC-2 (n = 60), blaNDM-5 (n = 14), blaNDM-1 (n = 11), blaKPC-3 (n = 4) and blaIMP-4 (n = 1). Among the 91 carbapenem-resistant Enterobacteriaceae (CRE), 85 isolates harboured at least one ESBL and/or AmpC gene, including 5 strains without carbapenemase-encoding genes. Moreover, 31 K. pneumoniae carried ompK35 and/or ompK36 mutations. MLST results showed that the K. pneumoniae belonged to 12 different STs, with ST11 being predominant (29/54; 53.7%). Overall, 17.6%, 25.3%, 41.8%, 65.9% and 100% of the CRE strains were susceptible to amikacin, trimethoprim/sulfamethoxazole, tetracycline, CAZ/AVI and ATM/AVI, respectively. CONCLUSION:This study revealed that CRE isolates differ significantly in their species, STs, porins and carbapenemase genes in a single Chinese hospital. ATM/AVI exhibited potent activity against CRE isolates, even for the most notorious double-carbapenemase-producers with porin defects, whereas CAZ/AVI was active against all the non-metallo-β-lactamase-producing isolates.

journal_name

J Glob Antimicrob Resist

journal_title

Journal of global antimicrobial resistance

authors

Wei J,Zou C,Wang D,Huang A,Niu S

doi

10.1016/j.jgar.2020.04.023

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

448-451

eissn

2213-7165

issn

2213-7173

pii

S2213-7165(20)30115-6

journal_volume

22

pub_type

杂志文章

相关文献

Journal of Global Antimicrobial Resistance文献大全
  • Resistance mechanisms and clinical characteristics of linezolid-resistant Enterococcus faecium isolates: A single-centre study in South Korea.

    abstract：OBJECTIVES:This study aimed to determine the prevalence of linezolid-resistant (LR) vancomycin-resistant enterococci and to investigate the mechanisms of linezolid resistance with clinical and microbiological characterisation. METHODS:All vancomycin-resistant Enterococcus faecium (VREF) isolated from blood and rectal ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.09.009

    authors： Cho SY,Kim HM,Chung DR,Kim SH,Huh HJ,Kang CI,Peck KR,Lee NY,Song JH

    更新日期：2018-03-01 00:00:00

  • Whole-genome sequencing of an NDM-1- and OXA-58-producing Acinetobacter towneri isolate from hospital sewage in Sichuan Province, China.

    abstract：OBJECTIVES:Acinetobacter spp. isolates carrying the blaNDM-1 gene are frequently reported. However, most reported blaNDM-1 genes are carried by clinical strains. Here we report a carbapenem-resistant Acinetobacter towneri isolate from hospital sewage in China co-harbouring blaNDM-1 and blaOXA-58 in the genome. METHODS...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.11.015

    authors： Jiang N,Zhang X,Zhou Y,Zhang Z,Zheng X

    更新日期：2019-03-01 00:00:00

  • Complete genome sequencing and comparative plasmid analysis of KPC-2-producing Klebsiella pneumoniae isolated from hospital sewage water in Japan.

    abstract：OBJECTIVES:The Klebsiella pneumoniae carbapenemase (blaKPC) gene is one of the most widespread carbapenemase genes in the world. However, there are few reports on KPC-producing bacteria in Japan. The aim of this study was therefore to investigate KPC-producing K. pneumoniae in Japan. METHODS:A KPC-2-producingK. pneumo...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2020.12.007

    authors： Eda R,Maehana S,Hirabayashi A,Nakamura M,Furukawa T,Ikeda S,Sakai K,Kojima F,Sei K,Suzuki M,Kitasato H

    更新日期：2020-12-26 00:00:00

  • Aminoquinolines afford resistance to cerebral malaria in susceptible mice.

    abstract：OBJECTIVES:Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. METHODS:In vitro testing was performed by the lactate dehydrogenase assay in chloroquine (CQ)-sensitive Plasmodium falci...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2020.07.027

    authors： Srbljanović J,Bobić B,Štajner T,Uzelac A,Opsenica I,Terzić-Jovanović N,Bauman N,Šolaja BA,Djurković-Djaković O

    更新日期：2020-12-01 00:00:00

  • Genomic features of a multidrug-resistant Enterobacter cloacae ST279 producing CTX-M-15 and AAC(6')-Ib-cr isolated from fatal infectious stomatitis in a crossed pit viper (Bothrops alternatus).

    abstract：OBJECTIVES:The widespread dissemination of extended-spectrum β-lactamase-producing Enterobacteriaceae has become a major issue in veterinary medicine. However, until now, there has been no report of bacteria with such a phenotype in infected snakes. The aim of this study was to report the first draft genome sequence of...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.11.009

    authors： de Carvalho MPN,Moura Q,Fernandes MR,Sellera FP,Pagotto AH,Stuginski DR,Castro RA,Sant'Anna SS,Grego KF,Lincopan N

    更新日期：2018-12-01 00:00:00

  • Genotypic and phylogenetic characterisation of a clinical Ralstonia pickettii strain carrying two novel OXA allelic variants, blaOXA-898 and blaOXA-899, isolated from a bloodstream infection in China.

    abstract：OBJECTIVES:Ralstonia pickettii has been increasingly recognised as an emerging opportunistic pathogen in hospital settings in recent years, especially in patients with prolonged hospital stay. Clinical manifestations associated with R. pickettii infection range from mild infections to severe invasive life-threatening i...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2020.02.020

    authors： Jiang T,Xu J,He F

    更新日期：2020-06-01 00:00:00

  • Draft genome sequence of an OXA-23, OXA-66, ADC-25 and TEM-1D co-producing Acinetobacter baumannii ST195 isolated from a patient with neonatal pneumonia in China.

    abstract：OBJECTIVES:The rapid spread of multidrug-resistant (MDR) Acinetobacter baumannii poses a substantial threat for morbidity and mortality worldwide. In particular, carbapenem-resistant A. baumannii has caused a severe challenge to human health. Here we reported the draft genome sequence of A. baumannii S131434, an OXA-23...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.11.008

    authors： Lv W,Zhang X,Hou M,Han D,Li Y,Xiong W

    更新日期：2019-03-01 00:00:00

  • Pharmacokinetics of meropenem in burn patients with infections caused by Gram-negative bacteria: Are we getting close to the right treatment?

    abstract：OBJECTIVES:Infections caused by multidrug-resistant Gram-negative bacteria are associated with high mortality. A relevant concern is the efficacy of antibiotic therapy in burn patients in whom pathophysiological changes strongly influence pharmacokinetic (PK) parameters. This study aimed to describe the PK parameters o...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.06.011

    authors： Corcione S,D'Avolio A,Loia RC,Pensa A,Segala FV,De Nicolò A,Fatiguso G,Romeo M,Di Perri G,Stella M,De Rosa FG

    更新日期：2020-03-01 00:00:00

  • Draft genome sequence of a Kluyvera intermedia isolate from a patient with a pancreatic abscess.

    abstract：:The genus Kluyvera comprises potential pathogens that can cause many infections. This study reports a Kluyvera intermedia strain (FOSA7093) from a pancreatic cyst specimen from a long-term hospitalised patient. Whole-genome sequencing (WGS) of the K. intermedia isolate was performed and the strain was reported as sens...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.05.007

    authors： Thele R,Gumpert H,Christensen LB,Worning P,Schønning K,Westh H,Hansen TA

    更新日期：2017-09-01 00:00:00

  • Emergence of an Escherichia coli strain co-harbouring mcr-1 and blaNDM-9 from a urinary tract infection in Taiwan.

    abstract：OBJECTIVES:Multidrug-resistant bacteria have become a serious threat worldwide. In particular, the coexistence of carbapenemase genes and mcr-1 leaves few available treatment options. Here we report a multidrug-resistant Escherichia coli isolate harbouring both mcr-1 and blaNDM-9 from a patient with a urinary tract inf...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.10.003

    authors： Lin YC,Kuroda M,Suzuki S,Mu JJ

    更新日期：2019-03-01 00:00:00

  • Complete genome sequence of multidrug-resistant Staphylococcus cohnii ssp. urealyticus strain SNUDS-2 isolated from farmed duck, Republic of Korea.

    abstract：OBJECTIVES:Staphylococcus cohnii has become increasingly recognized as a potential pathogen of clinically significant nosocomial and farm animal infections. This study was designed to determine the genome of a multidrug-resistant S. cohnii subsp. urealyticus strain SNUDS-2 isolated from a farmed duck in Korea. METHODS...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.05.008

    authors： Han JE,Lee S,Jeong DG,Yoon SW,Kim DJ,Lee MS,Kim HK,Park SK,Kim JH,Park SC

    更新日期：2017-09-01 00:00:00

  • Influence of age on the clinical efficacy of tigecycline in severely ill patients.

    abstract：OBJECTIVES:The aim of this study was to define the relationship between age and response to tigecycline among patients treated for complicated skin and soft-tissue infections (cSSTIs) and complicated intra-abdominal infections (cIAIs). METHODS:Pooled data derived from five European observational studies on the use of ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.03.018

    authors： Bassetti M,Guirao X,Montravers P,Rossolini GM,Sánchez García M,Sganga G,Eckmann C

    更新日期：2019-09-01 00:00:00

  • Evaluation of vancomycin MIC creep in Staphylococcus aureus.

    abstract：OBJECTIVES:Vancomycin is the primary treatment for methicillin-resistant Staphylococcus aureus (MRSA). However, an increasing proportion of MRSA isolates with high minimum inhibitory concentrations (MICs) within the susceptible range (vancomycin 'MIC creep') is being observed. The aim of this study was to assess the va...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.04.007

    authors： Diaz R,Ramalheira E,Afreixo V,Gago B

    更新日期：2017-09-01 00:00:00

  • Coexistence of blaKPC-2-IncN and mcr-1-IncX4 plasmids in a ST48 Escherichia coli strain in China.

    abstract：OBJECTIVES:The aim of this study was to explore the genomic content of a blaKPC-2- and mcr-1-harbouring Escherichia coli strain and to clarify the molecular mechanism for the transmission of multidrug resistance. METHODS:Antimicrobial susceptibility testing was conducted by the broth microdilution method to determine ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2020.08.023

    authors： Wang Y,Liu H,Wang Q,Du X,Yu Y,Jiang Y

    更新日期：2020-12-01 00:00:00

  • Antimicrobial resistance patterns of uropathogens isolated between 2012 and 2017 from a tertiary hospital in Northern Ethiopia.

    abstract：OBJECTIVES:Urinary tract infections (UTIs) are one of the most common infections in humans. Studies have shown that antibiotics for UTIs are usually prescribed empirically before the results of urine culture are available. The aim of the study was to assess the antimicrobial resistance patterns of bacteria isolated fro...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.01.022

    authors： Tuem KB,Desta R,Bitew H,Ibrahim S,Hishe HZ

    更新日期：2019-09-01 00:00:00

  • Evaluation of the in vitro antimicrobial activity of selected Saudi scorpion venoms tested against multidrug-resistant micro-organisms.

    abstract：OBJECTIVES:Scorpion venoms are a rich source of bioactive peptides with promising clinical value that may lead to the discovery and development of new drugs. The present study was designed to evaluate the in vitro antimicrobial activities of the venoms extracted from three medically important Saudi scorpions (Androcton...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.03.008

    authors： Al-Asmari AK,Alamri MA,Almasoudi AS,Abbasmanthiri R,Mahfoud M

    更新日期：2017-09-01 00:00:00

  • Carbapenem-resistant Acinetobacter baumannii isolates carrying blaOXA genes with upstream ISAba1: First report of a novel OXA subclass from Iran.

    abstract：OBJECTIVES:Carbapenem-resistant Acinetobacter baumannii (CRAB) have emerged as a serious threat to public-health worldwide. This study aimed to determine the antimicrobial susceptibility of A. baumannii isolates in Iran and to investigate oxacillinase-encoding determinants and their association with insertion sequence ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.12.011

    authors： Yazdansetad S,Najari E,Ghaemi EA,Javid N,Hashemi A,Ardebili A

    更新日期：2019-09-01 00:00:00

  • Individual feedback to reduce inappropriate antimicrobial prescriptions for treating acute upper respiratory infections in an outpatient setting of a Thai university hospital.

    abstract：OBJECTIVES:Excessive use of antimicrobial agents for acute upper respiratory infections (URIs) is one of the most common problems in clinical practice. Interventions are required to reduce antimicrobial overuse in these common infections. METHODS:During a 9-month study period (June 2014-February 2015), a quasi-experim...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.08.015

    authors： Rattanaumpawan P,Chuenchom N,Thamlikitkul V,Siriraj Antimicrobial Stewardship Program.

    更新日期：2018-03-01 00:00:00

  • Insertion sequences disrupting mgrB in carbapenem-resistant Klebsiella pneumoniae strains in Brazil.

    abstract：OBJECTIVES:This study aimed to characterise insertional mutations disturbing themgrB gene in carbapenem-resistant Klebsiella pneumoniae (CRKp). METHODS:A total of 118 clinical CRKp isolates were surveyed for polymyxin resistance and insertion sequence (IS) elements disruptingmgrB. RESULTS:Of the 118 isolates, 78 (66....

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2020.11.003

    authors： Silva DMD,Faria-Junior C,Nery DR,Oliveira PM,Silva LOR,Alves EG,Lima GRCEC,Pereira AL

    更新日期：2020-11-24 00:00:00

  • Antimicrobial susceptibility in hospitals in Hong Kong: The current status 2009-2011.

    abstract：:Hospitals in Hong Kong, like many hospitals in the world, are constantly challenged by the increasing rate of non-susceptible and multidrug-resistant organisms (MDROs). Accurate and timely surveillance is essential for effective control. The Hospital Authority of Hong Kong has developed a comprehensive antimicrobial s...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章,评审

    doi：10.1016/j.jgar.2014.05.008

    authors： Lai CK,Chuang WM,Kong MY,Siu HK,Tsang DN

    更新日期：2014-12-01 00:00:00

  • Draft genome sequences of two fluoroquinolone-resistant CTX-M-15-producing Escherichia coli ST90 (ST23 complex) isolated from a calf and a dairy cow in South America.

    abstract：OBJECTIVES:Farm animals have been recognised as important carriers and reservoirs of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli. The aim of this study was to report the draft genome sequences of two multidrug-resistant (MDR) CTX-M-15-producing E. coli strains (47VL and 13B) isolated from different ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.10.009

    authors： Sartori L,Fernandes MR,Ienne S,de Souza TA,Gregory L,Cerdeira L,Lincopan N

    更新日期：2017-12-01 00:00:00

  • Urinary tract infection in Uruguayan children: Aetiology, antimicrobial resistance and uropathogenic Escherichia coli virulotyping.

    abstract：:Uropathogenic Escherichia coli (UPEC) is the most frequent cause of urinary tract infection (UTI). Virulence factors (VFs) of UPEC in children are not well known. Circulating antibiotic resistance mechanisms in the community are increasing. In this study, the aetiological agents of UTI and antibiotic resistance mechan...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2014.08.003

    authors： Robino L,García-Fulgueiras V,Araujo L,Algorta G,Pírez MC,Vignoli R

    更新日期：2014-12-01 00:00:00

  • Detection of chromosomal and plasmid-mediated mechanisms of colistin resistance in Escherichia coli and Klebsiella pneumoniae from Indian food samples.

    abstract：OBJECTIVES:Numerous previous publications on the detection of bacterial isolates harbouring the mcr-1 gene from animals and humans strongly suggest an underlying route of transmission of colistin resistance via the food chain. The aim of this study was to investigate the presence of colistin-resistant (Col-R) bacteria ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.09.005

    authors： Ghafur A,Shankar C,GnanaSoundari P,Venkatesan M,Mani D,Thirunarayanan MA,Veeraraghavan B

    更新日期：2019-03-01 00:00:00

  • Long-range DHPS mutations unexpectedly increase Mycobacterium chimaera susceptibility to sulfonamides.

    abstract：:The two closely related mycobacteria, Mycobacterium intracellulare and Mycobacterium chimaera, exhibit a more than two-fold difference in their in vitro susceptibility to sulfonamides. Sulfonamides are antibiotics targeting the 6-hydroxymethyl-7,8-dihydropteroate synthase (DHPS) enzyme involved in the folate synthesis...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2013.05.003

    authors： Gotthard G,Muhammed Ameen S,Drancourt M,Chabriere E

    更新日期：2013-12-01 00:00:00

  • High burden of antimicrobial drug resistance in Asia.

    abstract：:The rapid development of antimicrobial resistance among micro-organisms is a serious public health concern. Moreover, the dissemination of antibiotic-resistant bacteria makes this issue a global problem, and Asia is no exception. For example, since New Delhi metallo-β-lactamase (NDM)-producing Enterobacteriaceae were ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章,评审

    doi：10.1016/j.jgar.2014.02.007

    authors： Lai CC,Lee K,Xiao Y,Ahmad N,Veeraraghavan B,Thamlikitkul V,Tambyah PA,Nelwan RH,Shibl AM,Wu JJ,Seto WH,Hsueh PR

    更新日期：2014-09-01 00:00:00

  • Extended-spectrum β-lactamase-producing Enterobacteriaceae from animal origin and wastewater in Tunisia: first detection of O25b-B23-CTX-M-27-ST131 Escherichia coli and CTX-M-15/OXA-204-producing Citrobacter freundii from wastewater.

    abstract：OBJECTIVES:This study aimed to isolate and characterise extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) isolates from animals and wastewater in Tunisia. METHODS:ESBL-E from wastewater (n=123 samples), faeces of healthy animals (poultry, sheep, goats and calves) (n=140) and raw milk from healthy cow...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.01.002

    authors： Sghaier S,Abbassi MS,Pascual A,Serrano L,Díaz-De-Alba P,Said MB,Hassen B,Ibrahim C,Hassen A,López-Cerero L

    更新日期：2019-06-01 00:00:00

  • Draft genome sequence of a multidrug-resistant blaOXA-69-producing Acinetobacter baumannii L13 isolated from Tarim River sample in China.

    abstract：OBJECTIVES:Acinetobacter baumannii (A. baumannii) is the world's most significant opportunistic pathogen that causes nosocomial infections; there is widespread health concern due to its ability to acquire multidrug resistance. This study reports a new variety of A. baumannii L13 isolated from Tarim River in Xinjiang Uy...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.05.022

    authors： Liu N,Zhu L,Zhang Z,Huang H,Jiang L

    更新日期：2019-09-01 00:00:00

  • Global genotype distribution of human clinical isolates of New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae; A systematic review.

    abstract：BACKGROUND AND AIM:The global rise of antimicrobial resistance among bacterial strains is a rapidly growing challenge and is becoming a major public health concern. This study documents the worldwide spread and genotype distribution of human clinical isolates of New Delhi metallo-β-lactamase-producing Klebsiella pneumo...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章,评审

    doi：10.1016/j.jgar.2020.10.016

    authors： Safavi M,Bostanshirin N,Hajikhani B,Yaslianifard S,van Belkum A,Goudarzi M,Hashemi A,Darban-Sarokhalil D,Dadashi M

    更新日期：2020-12-01 00:00:00

  • Trends and factors associated with antimicrobial resistance of Acinetobacter spp. invasive isolates in Europe: A country-level analysis.

    abstract：OBJECTIVES:This study investigated trends and factors associated with antimicrobial resistance (AMR) in Acinetobacter spp. in Europe. METHODS:Using data from EARS-Net, population-weighted multilevel logistic regression models with random intercepts for each participating country were performed to assess trends in Acin...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.05.024

    authors： Alvarez-Uria G,Midde M

    更新日期：2018-09-01 00:00:00

  • Antimicrobial resistance profiles and genotypes of extended-spectrum β-lactamase- and AmpC β-lactamase-producing Klebsiella pneumoniae isolated from dogs in Beijing, China.

    abstract：OBJECTIVES:Klebsiella pneumoniae, which exists in the intestinal and respiratory tracts of humans and animals, is an important conditional pathogen in many animals. The aim of the current study was to investigate the antimicrobial resistance profiles and genotypes of extended-spectrum β-lactamase (ESBL)- and AmpC β-lac...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.06.006

    authors： Liu Y,Yang Y,Chen Y,Xia Z

    更新日期：2017-09-01 00:00:00