Draft genome sequence of a Kluyvera intermedia isolate from a patient with a pancreatic abscess.

Abstract:

:The genus Kluyvera comprises potential pathogens that can cause many infections. This study reports a Kluyvera intermedia strain (FOSA7093) from a pancreatic cyst specimen from a long-term hospitalised patient. Whole-genome sequencing (WGS) of the K. intermedia isolate was performed and the strain was reported as sensitive to Danish-registered antibiotics although it had a fosA-like gene in the genome. There were nine contigs that aligned to a plasmid, and these contigs contained several heavy metal resistance gene homologues. Furthermore, a prophage was discovered in the genome. WGS represents an efficient tool for monitoring Kluyvera spp. and its role as a reservoir of multidrug resistance. Therefore, this susceptible K. intermedia genome has many characteristics that allow comparison of resistant K. intermedia that might be discovered in the future.

authors

Thele R,Gumpert H,Christensen LB,Worning P,Schønning K,Westh H,Hansen TA

doi

10.1016/j.jgar.2017.05.007

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

1-2

eissn

2213-7165

issn

2213-7173

pii

S2213-7165(17)30069-3

journal_volume

10

pub_type

杂志文章
  • New chalcone compound as a promising antileishmanial drug for an old neglected disease: Biological evaluation using radiolabelled biodistribution.

    abstract:OBJECTIVES:Treatment of leishmaniasis remains a challenge, especially due to the need for multiple painful injections, the toxicity of current drugs against the disease, their lack of efficacy and, lately, drug resistance. The aim of this study was to demonstrate the biological behaviour of 3-nitro-2'-hydroxy-4',6'-dim...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2017.11.012

    authors: Sousa-Batista AJ,Philipon CIMS,de Souza Albernaz M,Pinto SR,Rossi-Bergmann B,Santos-Oliveira R

    更新日期:2018-06-01 00:00:00

  • Forecasting models of infections due to carbapenem-resistant Gram-negative bacteria in an intensive care unit in an endemic area.

    abstract:OBJECTIVES:The aim of this study was to forecast the monthly incidence rates of infections [infections/1000 bed-days (IBD)] due to carbapenem-resistant Klebsiella pneumoniae (CRKP), carbapenem-resistant Pseudomonas aeruginosa (CRPA), carbapenem-resistant Acinetobacter baumannii (CRAB) and total carbapenem-resistant Gra...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.06.019

    authors: Karampatakis T,Tsergouli K,Iosifidis E,Antachopoulos C,Mouloudi E,Karyoti A,Tsakris A,Roilides E

    更新日期:2020-03-01 00:00:00

  • Polymyxin monotherapy versus polymyxin-based combination therapy against carbapenem-resistant Klebsiella pneumoniae: A systematic review and meta-analysis.

    abstract:OBJECTIVES:This meta-analysis was performed to compare polymyxin monotherapy and polymyxin-based combination therapy for carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections. METHODS:We conducted searches on MEDLINE, Embase and Cochrane Collaborative database for both observational studies and randomised cont...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.08.024

    authors: Hou SY,Wu D,Feng XH

    更新日期:2020-12-01 00:00:00

  • Individual feedback to reduce inappropriate antimicrobial prescriptions for treating acute upper respiratory infections in an outpatient setting of a Thai university hospital.

    abstract:OBJECTIVES:Excessive use of antimicrobial agents for acute upper respiratory infections (URIs) is one of the most common problems in clinical practice. Interventions are required to reduce antimicrobial overuse in these common infections. METHODS:During a 9-month study period (June 2014-February 2015), a quasi-experim...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2017.08.015

    authors: Rattanaumpawan P,Chuenchom N,Thamlikitkul V,Siriraj Antimicrobial Stewardship Program.

    更新日期:2018-03-01 00:00:00

  • Molecular mechanisms of clarithromycin resistance in Mycobacterium abscessus complex clinical isolates from Venezuela.

    abstract::In this study, 26 clinical isolates of Mycobacterium abscessus complex strains were characterised using available identification algorithms for the three species (M. abscessus, M. massiliense and M. bolletii) and the genotypic characteristics of clarithromycin (CLR) resistance were determined. Strains were identified ...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2015.05.007

    authors: Ramírez A,de Waard JH,Araque M

    更新日期:2015-09-01 00:00:00

  • Characterisation of a novel integrative and conjugative element ICESsD9 carrying erm(B) and tet(O) resistance determinants in Streptococcus suis, and the distribution of ICESsD9-like elements in clinical isolates.

    abstract::This study identified a novel integrative and conjugative element (ICESsD9) carrying erm(B) and tet(O) resistance determinants in Streptococcus suis D9 and determined its prevalence in clinical isolates. Comparative genome analysis was performed using Mauve and Artemis Comparison Tool visualisation programs. Inverse P...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2016.05.008

    authors: Huang K,Song Y,Zhang Q,Zhang A,Jin M

    更新日期:2016-12-01 00:00:00

  • Update on the activity of delafloxacin against acute bacterial skin and skin-structure infection isolates from European hospitals (2014-2019).

    abstract:OBJECTIVES:Delafloxacin is a broad-spectrum anionic fluoroquinolone with activity against Gram-positive and Gram-negative organisms, including methicillin-resistant Staphylococcus aureus. Both oral and intravenous formulations were approved for use in the treatment of acute bacterial skin and skin-structure infections ...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.09.027

    authors: Shortridge D,Pfaller MA,Streit JM,Flamm RK

    更新日期:2020-12-01 00:00:00

  • Extended-spectrum β-lactamase-producing Enterobacteriaceae from animal origin and wastewater in Tunisia: first detection of O25b-B23-CTX-M-27-ST131 Escherichia coli and CTX-M-15/OXA-204-producing Citrobacter freundii from wastewater.

    abstract:OBJECTIVES:This study aimed to isolate and characterise extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) isolates from animals and wastewater in Tunisia. METHODS:ESBL-E from wastewater (n=123 samples), faeces of healthy animals (poultry, sheep, goats and calves) (n=140) and raw milk from healthy cow...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.01.002

    authors: Sghaier S,Abbassi MS,Pascual A,Serrano L,Díaz-De-Alba P,Said MB,Hassen B,Ibrahim C,Hassen A,López-Cerero L

    更新日期:2019-06-01 00:00:00

  • Detection of chromosomal and plasmid-mediated mechanisms of colistin resistance in Escherichia coli and Klebsiella pneumoniae from Indian food samples.

    abstract:OBJECTIVES:Numerous previous publications on the detection of bacterial isolates harbouring the mcr-1 gene from animals and humans strongly suggest an underlying route of transmission of colistin resistance via the food chain. The aim of this study was to investigate the presence of colistin-resistant (Col-R) bacteria ...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2018.09.005

    authors: Ghafur A,Shankar C,GnanaSoundari P,Venkatesan M,Mani D,Thirunarayanan MA,Veeraraghavan B

    更新日期:2019-03-01 00:00:00

  • Possible application of high-dose vitamin C in the prevention and therapy of coronavirus infection.

    abstract::Coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses increase oxidative stress in the body leading to cellular and tissue damage. To combat this, administration of high-dose vitamin C (ascorbic acid or ascorbate), in addition to standard conventional supportive treat...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章,评审

    doi:10.1016/j.jgar.2020.09.025

    authors: Hoang BX,Shaw G,Fang W,Han B

    更新日期:2020-12-01 00:00:00

  • Whole-genome sequencing and single nucleotide polymorphisms in multidrug-resistant clinical isolates of Mycobacterium tuberculosis from the Philippines.

    abstract:OBJECTIVES:Thousands of cases of multidrug-resistant tuberculosis (TB) have been observed in the Philippines, but studies on the Mycobacterium tuberculosis (MTB) genotypes that underlie the observed drug resistance profiles are lacking. This study aimed to analyse the whole genomes of clinical MTB isolates representing...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2018.08.009

    authors: Roa MB,Tablizo FA,Morado EKD,Cunanan LF,Uy IDC,Ng KCS,Manalastas-Cantos KG,Reyes JM,Ganchua SKC,Ang CF,Kato-Maeda M,Cattamanchi A,Karaoz U,Destura RV,Lluisma AO

    更新日期:2018-12-01 00:00:00

  • Antimicrobial susceptibility and mechanisms of resistance of Greek Clostridium difficile clinical isolates.

    abstract:OBJECTIVES:This study examined the antimicrobial susceptibility and resistance mechanisms of Clostridium difficile recovered in Greek hospitals during 2012-2015. METHODS:C. difficile isolates (n=88) were collected from clinically-confirmed C. difficile infection from symptomatic patients in 10 Greek hospitals. Minimum...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2018.09.009

    authors: Chatedaki C,Voulgaridi I,Kachrimanidou M,Hrabak J,Papagiannitsis CC,Petinaki E

    更新日期:2019-03-01 00:00:00

  • Risk factors for carbapenem-resistant Klebsiella pneumoniae infection: A meta-analysis.

    abstract:OBJECTIVES:Rates of nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) have increased. A meta-analysis was conducted to explore risk factors for CRKP infection in order to provide a theoretical basis for reducing the CRKP infection rate and actively preventing CRKP infection. METHODS:Onl...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.09.006

    authors: Li J,Li Y,Song N,Chen Y

    更新日期:2020-06-01 00:00:00

  • Complete genome sequencing and comparative plasmid analysis of KPC-2-producing Klebsiella pneumoniae isolated from hospital sewage water in Japan.

    abstract:OBJECTIVES:The Klebsiella pneumoniae carbapenemase (blaKPC) gene is one of the most widespread carbapenemase genes in the world. However, there are few reports on KPC-producing bacteria in Japan. The aim of this study was therefore to investigate KPC-producing K. pneumoniae in Japan. METHODS:A KPC-2-producingK. pneumo...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.12.007

    authors: Eda R,Maehana S,Hirabayashi A,Nakamura M,Furukawa T,Ikeda S,Sakai K,Kojima F,Sei K,Suzuki M,Kitasato H

    更新日期:2020-12-26 00:00:00

  • IncC blaKPC-2-positive plasmid characterised from ST648 Escherichia coli.

    abstract:OBJECTIVES:This study describes the characterisation of type 2 IncC plasmids pC-Ec20-KPC and pC-Ec2-KPC, carrying theblaKPC-2 gene, from two multiresistant Escherichia coli recovered in University Hospital of Larissa (Greece) in 2018. METHODS:E. coli strains Ec-2Lar and Ec-20Lar were recovered from rectal swabs of two...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.05.001

    authors: Papagiannitsis CC,Bitar I,Malli E,Tsilipounidaki K,Hrabak J,Petinaki E

    更新日期:2019-12-01 00:00:00

  • Investigation of pre-clinical pharmacokinetic parameters of atovaquone nanosuspension prepared using a pH-based precipitation method and its pharmacodynamic properties in a novel artemisinin combination.

    abstract:OBJECTIVES:Recently, a growing resistance to antimalarial drugs such as chloroquine, sulfadoxine-pyrimethamine, artemisinin derivatives and mefloquine has been observed. The pharmacokinetic limitation of the current therapy and multi-drug resistance has resulted in an urgent need to study the new antimalarial combinati...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.02.018

    authors: Kathpalia H,Juvekar S,Mohanraj K,Apsingekar M,Shidhaye S

    更新日期:2020-09-01 00:00:00

  • Whole genome sequence of an Escherichia coli ST410 isolate co-harbouring blaNDM-5, blaOXA-1, blaCTX-M-15, blaCMY-2, aac(3)-IIa and aac(6')-Ib-cr genes isolated from a patient with bloodstream infection in China.

    abstract:OBJECTIVES:Mortality associated with carbapenemase-producing Enterobacteriaceae is high as there are few therapeutic options. Escherichia coli sequence type 410 (ST410) is currently an international high-risk clone and is responsible for a large number of clinical infections. Here we report the draft genome sequence of...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.10.027

    authors: Huang J,Ma S,Yu Q,Fu M,Shao L,Shan X,Li X

    更新日期:2019-12-01 00:00:00

  • A systematic review on the prevalence of extended-spectrum beta lactamase-producing Gram-negative bacteria in Nigeria.

    abstract:OBJECTIVE:There are numerous reported cases of extended-spectrum beta-lactamases (ESBLs) producing Enterobacteriaceae in Nigeria. Yet, there are regions in Nigeria where cases of ESBL were under-reported. The review aims to assess the prevalence of ESBL-producing Gram-negative bacteria in Nigeria and the genes involved...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章,评审

    doi:10.1016/j.jgar.2020.04.010

    authors: Tanko N,Bolaji RO,Olayinka AT,Olayinka BO

    更新日期:2020-09-01 00:00:00

  • Rectal screening displays high negative predictive value for bloodstream infection with (ESBL-producing) Gram-negative bacteria in neonates with suspected sepsis in a low-resource setting neonatal care unit.

    abstract:OBJECTIVES:We analysed the concordance of rectal swab isolates and blood culture for Gram-negative bacteria (GNB) isolates in neonates with a suspicion of neonatal sepsis admitted to a neonatal care unit in Haiti. METHODS:We matched pairs of blood and rectal samples taken on the date of suspected sepsis onset in the s...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.08.017

    authors: Lenglet A,Schuurmans J,Ariti C,Borgundvaag E,Charles K,Badjo C,Clezy K,Evens E,Senat-Delva R,Berthet M,Lekkerkerker M,McRae M,Wertheim H,Hopman J

    更新日期:2020-12-01 00:00:00

  • Case series of carbapenemase-producing Enterobacteriaceae osteomyelitis: Feel it in your bones.

    abstract:OBJECTIVES:Limited data have been reported regarding osteomyelitis due to carbapenemase-producing Enterobacteriaceae (CPE), including co-infections with extended-spectrum β-lactamase (ESBL)-producing micro-organisms. METHODS:We conducted a retrospective study in a reference centre for bone and joint infections from 20...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.08.007

    authors: Davido B,Noussair L,Saleh-Mghir A,Salomon E,Bouchand F,Matt M,Lawrence C,Bauer T,Herrmann JL,Perronne C,Gaillard JL,Rottman M,Dinh A

    更新日期:2020-12-01 00:00:00

  • Whole-genome sequencing reveals misidentification of a multidrug-resistant urine clinical isolate as Corynebacterium urealyticum.

    abstract:OBJECTIVES:Corynebacterium urealyticum is a non-diphtherial urease-producing clinically relevant corynebacterium associated with urinary tract infections. Most clinical C. urealyticum isolates are multidrug-resistant. Whole-genome sequencing (WGS) of C. urealyticum VH4248 isolated from a clinical urine sample at Hospit...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.07.020

    authors: Rocha DJP,Azevedo V,Brenig B,Silva A,Blom J,Ramos RT,Aguiar ERG,Chapartegui-González I,Fernández-Martínez M,Martínez-Martínez L,Pacheco LGC,Navas J

    更新日期:2020-12-01 00:00:00

  • High prevalence of blaCMY AmpC beta-lactamase in ESBL co-producing Escherichia coli and Klebsiella spp. clinical isolates in the northeast of Iran.

    abstract:OBJECTIVE:The production of β-lactamase enzymes such as AmpC β-lactamases and extended-spectrum β-lactamases (ESBLs) is among the main mechanisms for resistance to expanded-spectrum cephalosporins. The present study was conducted to investigate the prevalence and molecular epidemiology of plasmid-mediated AmpC beta (β)...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.03.011

    authors: Rizi KS,Mosavat A,Youssefi M,Jamehdar SA,Ghazvini K,Safdari H,Amini Y,Farsiani H

    更新日期:2020-09-01 00:00:00

  • Infections by OXA-48-like-producing Klebsiella pneumoniae non-co-producing extended-spectrum beta-lactamase: Can they be successfully treated with cephalosporins?

    abstract:BACKGROUND:OXA-48 is an Ambler class D β-lactamase that hydrolyses penicillin and imipenem but has poor hydrolytic activity against cephalosporins. However, very few clinical experiences of treating extended-spectrum β-lactamase (ESBL)-negative OXA-48 producers with cephalosporins have been published. OBJECTIVES:The a...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.02.016

    authors: Escolà-Vergé L,Larrosa N,Los-Arcos I,Viñado B,González-López JJ,Pigrau C,Almirante B,Len O

    更新日期:2019-12-01 00:00:00

  • Molecular characterisation of the clonal emergence of high-level ciprofloxacin-monoresistant Haemophilus influenzae in the Region of Southern Denmark.

    abstract::Haemophilus influenzae is an important human pathogen usually susceptible to quinolones. Here we report the emergence of high-level ciprofloxacin-monoresistant H. influenzae in the Region of Southern Denmark. Four isolates were collected for phenotypic and molecular characterisation using whole-genome sequencing (WGS)...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2015.12.004

    authors: Fuursted K,Hartmeyer GN,Stegger M,Andersen PS,Justesen US

    更新日期:2016-06-01 00:00:00

  • Impact of ethnic disparities on the treatment outcomes of HIV-negative drug-resistant tuberculosis patients in Kuala Lumpur, Malaysia: A call for a culturally-sensitive community intervention approach.

    abstract:OBJECTIVE:Little is known about the treatment outcomes of HIV-negative drug-resistant tuberculosis (TB) patients in Malaysia. With respect to this issue, this study aimed to determine factors associated with unsuccessful treatment outcomes among drug-resistant TB patients at the Institute of Respiratory Medicine, Kuala...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.05.009

    authors: Shariff NM,Shah SA,Kamaludin F

    更新日期:2019-12-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus nasal colonisation amongst healthcare workers in Kurdistan Region, Iraq.

    abstract:OBJECTIVES:The aim of this study was to determine the prevalence of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) among healthcare workers (HCWs) compared with non-HCWs at Duhok city, Kurdistan Region, northern Iraq. METHODS:A total of 182 HCWs with different occupations and working in different...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2017.01.010

    authors: Hussein NR,Assafi MS,Ijaz T

    更新日期:2017-06-01 00:00:00

  • Emergence of an Escherichia coli strain co-harbouring mcr-1 and blaNDM-9 from a urinary tract infection in Taiwan.

    abstract:OBJECTIVES:Multidrug-resistant bacteria have become a serious threat worldwide. In particular, the coexistence of carbapenemase genes and mcr-1 leaves few available treatment options. Here we report a multidrug-resistant Escherichia coli isolate harbouring both mcr-1 and blaNDM-9 from a patient with a urinary tract inf...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2018.10.003

    authors: Lin YC,Kuroda M,Suzuki S,Mu JJ

    更新日期:2019-03-01 00:00:00

  • Coexistence of blaKPC-2-IncN and mcr-1-IncX4 plasmids in a ST48 Escherichia coli strain in China.

    abstract:OBJECTIVES:The aim of this study was to explore the genomic content of a blaKPC-2- and mcr-1-harbouring Escherichia coli strain and to clarify the molecular mechanism for the transmission of multidrug resistance. METHODS:Antimicrobial susceptibility testing was conducted by the broth microdilution method to determine ...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.08.023

    authors: Wang Y,Liu H,Wang Q,Du X,Yu Y,Jiang Y

    更新日期:2020-12-01 00:00:00

  • In vitro activity of fosfomycin against mucoid and non-mucoid Pseudomonas aeruginosa strains.

    abstract:OBJECTIVES:Pseudomonas aeruginosa is the most frequent infectious agent in cystic fibrosis patients. P. aeruginosa resistance to first line antibiotics limits therapeutic options, but the therapeutic potential of older generation antibiotics, such as fosfomycin is under investigation. Fosfomycin does not belong to any ...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2020.02.014

    authors: Bressan A,Rodio DM,Stangherlin F,Puggioni G,Ambrosi C,Arcari G,Carattoli A,Antonelli G,Pietropaolo V,Trancassini M

    更新日期:2020-03-01 00:00:00

  • Opening Pandora's box: High-level resistance to antibiotics of last resort in Gram-negative bacteria from Nigeria.

    abstract:OBJECTIVES:The aim of this study was to determine the percentage of antimicrobial-resistant isolates and the associated resistance mechanisms in Gram-negative bacteria from South Western Nigeria. METHODS:A total of 306 non-duplicate unbiased Gram-negative isolates were recovered from patients admitted to three teachin...

    journal_title:Journal of global antimicrobial resistance

    pub_type: 杂志文章

    doi:10.1016/j.jgar.2019.10.016

    authors: Ogbolu DO,Piddock LJV,Webber MA

    更新日期:2020-06-01 00:00:00