Abstract:
BACKGROUND:Fungal keratitis (FK) has been shown to be a climate-sensitive disease. The differentiation between FK from bacterial keratitis (BK) was difficult. The purpose of this study was to compare the bacteriology and mycology between tropical and subtropical Taiwan and to investigate the independent risk factors for identification of fungi from bacteria. METHODS:Two hundred ninety-seven patients with clinical suspected microbial keratitis were prospectively enrolled. A fungal to bacteria rate (FBR), the number of fungi divided by bacteria identified, was determined to estimate the prevalence of fungi and bacteria. Clinical presentation, profiles of microorganisms, and predisposing risk factors were determined. Univariate and multivariate logistic regression analysis were used to investigate the independent risk factors. RESULTS:A total of 82 fungi and 143 bacteria were laboratory confirmed. The identification rate of fungus was higher in tropical Taiwan (p = 0.010). Among the fungi and bacteria confirmed, the FBR was 0.29 (22.4% vs. 77.6%) in subtropical Taiwan, and 0.70 (41.3% vs. 58.7%) in tropical Taiwan. Samples obtained in tropical area (p = 0.019), ocular trauma (p = 0.019), and plant exposure (p = 0.003) were independent risk factors for identification of fungus from bacteria. The predominant fungus isolated from corneal scraping were Fusarium solani (25%) and Trichosporon faecale (25%) in subtropical Taiwan; in tropical Taiwan was Fusarium spp. (50%). CONCLUSIONS:The identification rate of fungus was higher in tropical Taiwan than subtropical Taiwan. Awareness of the local epidemiology is crucial for early diagnosis of fungal keratitis in tropical area.
journal_name
Ann Clin Microbiol Antimicrobjournal_title
Annals of clinical microbiology and antimicrobialsauthors
Chen CA,Hsu SL,Hsiao CH,Ma DH,Sun CC,Yu HJ,Fang PC,Kuo MTdoi
10.1186/s12941-020-00353-3subject
Has Abstractpub_date
2020-03-30 00:00:00pages
11issue
1issn
1476-0711pii
10.1186/s12941-020-00353-3journal_volume
19pub_type
杂志文章abstract::At the time of writing, the SARS-CoV-2 virus has infected more than 49 million people causing more than 1.2 million deaths worldwide since its emergence from Wuhan, China in December 2019. Vaccine development against SARS-CoV-2 has drawn the global attention in order to stop the spread of the virus, with more than 10 ...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,评审
doi:10.1186/s12941-020-00402-x
更新日期:2020-11-30 00:00:00
abstract:BACKGROUND:Training of infectious disease (ID) specialists is structured on classical clinical microbiology training in Turkey and ID specialists work as clinical microbiologists at the same time. Hence, this study aimed to determine the clinical skills and knowledge required by clinical microbiologists. METHODS:A cro...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-10-38
更新日期:2011-12-16 00:00:00
abstract:BACKGROUND:Chenopodium ambrosioides and Kielmeyera neglecta are plants traditionally used in Brazil to treat various infectious diseases. The study of the biological activities of these plants is of great importance for the detection of biologically active compounds. METHODS:Extracts from these plants were extracted w...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-11-20
更新日期:2012-07-28 00:00:00
abstract:BACKGROUND:Mycetoma is a chronic mutilating disease of the skin and the underlying tissues caused by fungi or bacteria. Although recently included in the list of neglected tropical diseases by the World Health Organization, strategic control and preventive measures are yet to be outlined. Thus, it continues to pose hug...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,评审
doi:10.1186/s12941-018-0287-4
更新日期:2018-08-10 00:00:00
abstract:BACKGROUND:In 2002 we investigated an outbreak comprising 231 patients in Norway, caused by Pseudomonas aeruginosa and linked to the use of contaminated mouth swabs called Dent-O-Sept. Here we describe the extent of contamination of the swabs, and identify critical points in the production process that made the contami...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-6-3
更新日期:2007-03-13 00:00:00
abstract::An 87 -year-old female who was undergoing peritoneal dialysis presented with peritonitis caused by Alcaligenes faecalis and Pantoea agglomerans in consecutive years. With the following report we discuss the importance of these unusual microorganisms in peritoneal dialysis patients. ...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-10-12
更新日期:2011-04-10 00:00:00
abstract:BACKGROUND:Klebsiella pneumoniae is a frequent nosocomial pathogen, with the multidrug-resistant (MDR) K. pneumoniae being a major public health concern, frequently causing difficult-to-treat infections worldwide. The aim of this study was to investigate the molecular characterization of clinical MDR Klebsiella pneumon...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-13-16
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Miscarriage and preterm delivery are the most important challenges of pregnancy. Different bacterial and viral infection may cause miscarriage and preterm delivery. Among bacterial factors, Mycoplasma genitalium and Chlamydia trachomatis have the most important role and human papilloma virus (HPV) is the lea...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-018-0276-7
更新日期:2018-06-04 00:00:00
abstract:INTRODUCTION:Antibiotic resistance decreases success of Helicobacter pylori (Hp) eradication. Recently published results show low rate of resistance and better compliance with moxifloxacin based regiments. AIMS&METHODS: Whether 7 days moxifloxacin with lansoprasole and amoxycillin can be compared with 10 days moxifloxa...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,随机对照试验
doi:10.1186/1476-0711-9-13
更新日期:2010-04-15 00:00:00
abstract:BACKGROUND:Distinct virulence factors of H. pylori have been described: the vaculating cytotoxin (vacA), the cytotoxin associated gene (cagA), the induced by contact with epithelium factor Antigen (iceA gene) and the outer membrane protein oipA. In Tunisia, there are no data regarding the pattern of H. pylori genotypes...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,多中心研究
doi:10.1186/1476-0711-9-10
更新日期:2010-03-19 00:00:00
abstract:BACKGROUND:This study aimed to evaluate in vitro susceptibility to ceftobiprole of clinical strains identified from prosthetic joint infections (PJIs) compared to that of the associations currently recommended for post-operative empirical antibiotic therapy (PEAT) (vancomycin with either cefepime, third-generation ceph...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-020-00351-5
更新日期:2020-03-21 00:00:00
abstract:BACKGROUND:Malaria and HIV/AIDS are the two most common infections in sub-Sahara Africa. There are hypotheses and study reports on the possible association between these two infections, hence the prevalence and outcome of their co-infection in an endemic population will be important in defining healthcare strategies. A...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-015-0064-6
更新日期:2015-03-07 00:00:00
abstract:BACKGROUND:Tuberculous meningitis (TBM) caused by Mycobacterium tuberculosis resistant to antituberculosis drugs is an increasingly common clinical problem. This study aimed to evaluate drug resistance profiles of TBM isolates in adult patients in nine European countries involving 32 centers to provide insight into the...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,多中心研究
doi:10.1186/s12941-015-0107-z
更新日期:2015-11-04 00:00:00
abstract:BACKGROUND:Leishmaniasis and malaria are the two most common parasitic diseases and responsible for large number of deaths per year particularly in developing countries like Pakistan. Majority of Pakistan population rely on medicinal plants due to their low socio-economic status. The present review was designed to gath...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,评审
doi:10.1186/s12941-016-0170-0
更新日期:2016-09-20 00:00:00
abstract:BACKGROUND:Persistent bacteremia occurs in at least 30% of patients with Staphylococcus aureus bloodstream infection (SAB) and may be attributable to a dysregulated host immune response. Neutrophils interact with a variety of S. aureus microbial factors, including lipoteichoic acid (LTA), to activate phagocytic functio...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-020-00392-w
更新日期:2020-11-03 00:00:00
abstract:BACKGROUND:Penicillium sp., other than P. marneffei, is an unusual cause of invasive disease. These organisms are often identified in immunosuppressed patients, either due to human immunodeficiency virus or from immunosuppressant medications post-transplantation. They are a rarely identified cause of infection in immun...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-4-21
更新日期:2005-12-21 00:00:00
abstract:INTRODUCTION:The aim of this study was to show the emergence of the qnrD gene among fluoroquinolone-resistant Morganella morganii isolate. The occurrence of mutations in DNA gyrase (gyrA and gyrB) and topoisomerase IV (parC,parE) genes was also investigated in this strain. METHODOLOGY:95 clinical Enterobacteria were s...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-014-0034-4
更新日期:2014-08-09 00:00:00
abstract:BACKGROUND:Farnesol is a sesquiterpene alcohol produced by many organisms, and also found in several essential oils. Its role as a quorum sensing molecule and as a virulence factor of Candida albicans has been well described. Studies revealed that farnesol affect the growth of a number of bacteria and fungi, pointing t...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-8-13
更新日期:2009-04-29 00:00:00
abstract:BACKGROUND:Helicobacter pylori has been strongly associated with chronic gastritis, peptic and duodenal ulcers, and it is a risk factor for gastric cancer. Three major virulence factors of H. pylori have been described: the vacuolating toxin (VacA), the cytotoxin-associated gene product (CagA) and the adhesion protein ...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-8-14
更新日期:2009-04-30 00:00:00
abstract:BACKGROUND:Carbapenemase-producing Klebsiella pneumoniae (CPKP) strains have emerged as a major problem for healthcare systems. The aim of this study was to determine the circulating clones and analyze the clinical and molecular characteristics of CPKP in our hospital. METHODS:A total of 74 carbapenemase producers col...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-015-0109-x
更新日期:2016-01-19 00:00:00
abstract:BACKGROUND:Empiric antimicrobial therapy (EAMT) using imipenem/colistin is commonly prescribed as a first line therapy in critically ill patients with severe sepsis. We aimed to assess the appropriateness of prescribing imipenem/colistin as EAMT in ICU patients. METHODS:A 3-year observational prospective study include...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-018-0292-7
更新日期:2018-11-16 00:00:00
abstract::Mycobacterium bovis BCG vaccine significantly reduces the risk of tuberculosis by 50% and continues to be used to prevent tuberculosis around the world. However, it has been shown to be ineffective in some geographical regions. The existence of different BCG strains was described more than 60 years ago, these vary in ...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-3-10
更新日期:2004-06-03 00:00:00
abstract::A panel of national experts was convened by the Brazilian Infectious Diseases Society in order to organize the national recommendations for the management of zika virus infection. The focus of this document is the diagnosis, both clinical and laboratorial, and appropriate treatment of the diverse manifestations of thi...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,评审
doi:10.1186/s12941-016-0172-y
更新日期:2016-09-29 00:00:00
abstract:BACKGROUND:Cat-scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae and B. clarridgeiae. The typical manifestations of CSD include regional lymphadenitis and fever. However, CSD can have a wide variety of clinical manifestations that can lead to incorrect diagnoses and prolonged hospital stays. ...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-019-0322-0
更新日期:2019-07-15 00:00:00
abstract:BACKGROUND:Escherichia coli is the commonest cause of community and nosocomial urinary tract infection (UTI). Antibiotic treatment is usually empirical relying on susceptibility data from local surveillance studies. We therefore set out to determine levels of resistance to 8 commonly used antimicrobial agents amongst a...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-7-13
更新日期:2008-06-18 00:00:00
abstract:BACKGROUND:The emergence of Mycobacterium tuberculosis strains resistant to antituberculosis agents has recently received increased attention owing largely to the dramatic outbreaks of multi drug resistance tuberculosis (MDR-TB). METHODS:Patients residing in Zonguldak and Kayseri provinces of Turkey with, pulmonary tu...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-1-6
更新日期:2002-12-16 00:00:00
abstract:BACKGROUND:Central line-associated bloodstream infections (CLABs) have long been associated with excess lengths of stay, increased hospital costs and mortality attributable to them. Different studies from developed countries have shown that practice bundles reduce the incidence of CLAB in intensive care units. However,...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,多中心研究
doi:10.1186/1476-0711-12-10
更新日期:2013-05-04 00:00:00
abstract:BACKGROUND:The evolving epidemiology of methicillin resistant Staphylococcus aureus (MRSA) is characterized by the emergence of infections caused by non multiresistant MRSA carrying staphylococcal chromosomal cassette (SCC)mec IV or V in the healthcare settings. A molecular epidemiological analysis of non multiresistan...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/1476-0711-11-17
更新日期:2012-06-19 00:00:00
abstract::Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important bacterial pathogens that causes infection with a high mortality rate due to resistance to different antibiotics. This bacterium prompts extensive tissue damage with varying factors of virulence, and its biofilm production causes chronic and...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章,评审
doi:10.1186/s12941-020-00389-5
更新日期:2020-09-30 00:00:00
abstract:BACKGROUND:Antibiotic resistance is a defense mechanism, harbored by pathogens to survive under unfavorable conditions. Among several antibiotic resistant microbial consortium, Staphylococcus aureus is one of the most havoc microorganisms. Staphylococcus aureus encodes a unique enzyme 6-hydroxymethyl-7,8-dihydropterin ...
journal_title:Annals of clinical microbiology and antimicrobials
pub_type: 杂志文章
doi:10.1186/s12941-018-0266-9
更新日期:2018-04-02 00:00:00