Abstract：
BACKGROUND:Penicillium sp., other than P. marneffei, is an unusual cause of invasive disease. These organisms are often identified in immunosuppressed patients, either due to human immunodeficiency virus or from immunosuppressant medications post-transplantation. They are a rarely identified cause of infection in immunocompetent hosts. CASE PRESENTATION:A 51 year old African-American female presented with an acute abdomen and underwent an exploratory laparotomy which revealed an incarcerated peristomal hernia. Her postoperative course was complicated by severe sepsis syndrome with respiratory failure, hypotension, leukocytosis, and DIC. On postoperative day 9 she was found to have an anastamotic breakdown. Pathology from the second surgery showed transmural ischemic necrosis with angioinvasion of a fungal organism. Fungal blood cultures were positive for Penicillium chrysogenum and the patient completed a 6 week course of amphotericin B lipid complex, followed by an extended course oral intraconazole. She was discharged to a nursing home without evidence of recurrent infection. DISCUSSION:Penicillium chrysogenum is a rare cause of infection in immunocompetent patients. Diagnosis can be difficult, but Penicillium sp. grows rapidly on routine fungal cultures. Prognosis remains very poor, but aggressive treatment is essential, including surgical debridement and the removal of foci of infection along with the use of amphotericin B. The clinical utility of newer antifungal agents remains to be determined.
journal_name
Ann Clin Microbiol Antimicrobjournal_title
Annals of clinical microbiology and antimicrobialsauthors
Barcus AL,Burdette SD,Herchline TEdoi
10.1186/1476-0711-4-21keywords:
subject
Has Abstractpub_date
2005-12-21 00:00:00pages
21issn
1476-0711pii
1476-0711-4-21journal_volume
4pub_type
杂志文章abstract：BACKGROUND:Drug resistance in Mycobacterium tuberculosis (MTB) is a major health issue worldwide. Recently, next-generation sequencing (NGS) technology has begun to be used to detect resistance genes of MTB. We aimed to assess the clinical usefulness of Ion S5 NGS TB research panel for detecting MTB resistance in Korea...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-018-0300-y
更新日期：2019-01-03 00:00:00
abstract：:For centuries, plants have been used in traditional medicines and there has been recent interest in the chemopreventive properties of compounds derived from plants. In the present study, we investigated the antibutyrylcholinestrasic (anti-BuChE) and antioxidant (against some free radicals) activities of extracts from ...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-10-32
更新日期：2011-08-31 00:00:00
abstract：:Resistance to beta-lactam antibiotics in enteric Gram-negative bacilli may be difficult to detect using standard methods of either Kirby-Bauer disc diffusion (KBDD) or broth dilution for minimal inhibitory concentration (MIC). This difficulty is due to genetic differences in resistance determinants, differences in lev...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-3-13
更新日期：2004-07-15 00:00:00
abstract：BACKGROUND:Carbapenemase-producing Klebsiella pneumoniae (CPKP) strains have emerged as a major problem for healthcare systems. The aim of this study was to determine the circulating clones and analyze the clinical and molecular characteristics of CPKP in our hospital. METHODS:A total of 74 carbapenemase producers col...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-015-0109-x
更新日期：2016-01-19 00:00:00
abstract：BACKGROUND:Fungal keratitis (FK) has been shown to be a climate-sensitive disease. The differentiation between FK from bacterial keratitis (BK) was difficult. The purpose of this study was to compare the bacteriology and mycology between tropical and subtropical Taiwan and to investigate the independent risk factors fo...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-020-00353-3
更新日期：2020-03-30 00:00:00
abstract：BACKGROUND:Recently, new carbapenemases in Enterobacteriaceae strains and non-fermentative gram-negative bacilli have been reported. The New Delhi metallo-β-lactamase-1 (NDM-1) is a major problem around the world. The purpose of this article is to address the NDM-1 Klebsiella pneumoniae epidemic detected in eight cases...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-016-0118-4
更新日期：2016-02-09 00:00:00
abstract：BACKGROUND:Miscarriage and preterm delivery are the most important challenges of pregnancy. Different bacterial and viral infection may cause miscarriage and preterm delivery. Among bacterial factors, Mycoplasma genitalium and Chlamydia trachomatis have the most important role and human papilloma virus (HPV) is the lea...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-018-0276-7
更新日期：2018-06-04 00:00:00
abstract：BACKGROUND:Integrons play important role in the spread and maintenance of antimicrobial resistance among strains of Escherichia coli (E. coli) and other species of Enterobacteriaceae. This study investigated the prevalence of class 1 and 2 integrons among E. coli strains isolated from aquaculture water of fish fields i...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-015-0096-y
更新日期：2015-07-31 00:00:00
abstract：BACKGROUND:Accurate identification of isolates belonging to genus Enterococcus, Streptococcus, coagulase-negative Staphylococcus, and Lactococcus at the species level is necessary to provide a better understanding of their pathogenic potential, to aid in making clinical decisions, and to conduct epidemiologic investiga...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-11-31
更新日期：2012-11-27 00:00:00
abstract：BACKGROUND:The in vitro activity of tigecycline and comparator agents was evaluated against Gram-positive and Gram-negative isolates collected in Latin American centers between 2004 and 2015 as part of the Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) global surveillance study. METHODS:Minimum inhibitory co...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-017-0222-0
更新日期：2017-07-12 00:00:00
abstract：BACKGROUND:The vast majority of patients with peritonsillar abscess (PTA) recover uneventfully on abscess drainage and antibiotic therapy. However, occasionally patient´s condition deteriorates as the infection spread in the upper airway mucosa, through cervical tissues, or hematogenously. The bacterial etiology of PTA...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章,评审
doi：10.1186/s12941-020-00375-x
更新日期：2020-07-30 00:00:00
abstract：BACKGROUND:The evolving epidemiology of methicillin resistant Staphylococcus aureus (MRSA) is characterized by the emergence of infections caused by non multiresistant MRSA carrying staphylococcal chromosomal cassette (SCC)mec IV or V in the healthcare settings. A molecular epidemiological analysis of non multiresistan...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-11-17
更新日期：2012-06-19 00:00:00
abstract：BACKGROUND:Urinary tract infections (UTI) can lead to poor maternal and perinatal outcomes. Investigating epidemiology of UTI and antibiotics sensitivity among pregnant women is fundamental for care-givers and health planners. METHODS:A cross sectional study has been conducted at Khartoum north teaching hospital Anten...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-10-2
更新日期：2011-01-18 00:00:00
abstract：BACKGROUND:Co-infection of HIV with HBV is common in West Africa but little information is available on the effects of HBV on short-term therapy for HIV patients. A 28 day longitudinal study was conducted to examine short-term antiretroviral therapy (ART) outcomes in HIV infected individuals with HBV co-infection. MET...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-016-0152-2
更新日期：2016-06-02 00:00:00
abstract：INTRODUCTION:During clinical use, gastrointestinal endoscopes are grossly contaminated with patient's native flora. These endoscopes undergo reprocessing to prevent infectious transmission upon future use. Endoscopy-associated infections and outbreaks have been reported, with a recent focus on the transmission of multi...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章,评审
doi：10.1186/s12941-018-0289-2
更新日期：2018-10-10 00:00:00
abstract：:Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important bacterial pathogens that causes infection with a high mortality rate due to resistance to different antibiotics. This bacterium prompts extensive tissue damage with varying factors of virulence, and its biofilm production causes chronic and...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章,评审
doi：10.1186/s12941-020-00389-5
更新日期：2020-09-30 00:00:00
abstract：BACKGROUND:Disinfection, antisepsis and sterilization (DAS) practices are of critical importance in hospital practice. This study aims to investigate the daily DAS practices of private hospitals in Istanbul, Turkey. METHODS:The DAS practices of 155 private hospitals in Istanbul province were investigated using a quest...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-015-0073-5
更新日期：2015-03-19 00:00:00
abstract：BACKGROUND:The aim of the present work was to evaluate the antibacterial effect of 3,4-DHPEA-EA (methyl-4-(2-(3,4-dihydroxyphenethoxy)-2-oxoethyl)-3-formyl-2-methyl-3,4-dihydro-2H-pyran-5-carboxylate), a derivate of oleuropein, against a range of Gram-positive bacteria, including ATCC strains, food and clinical isolate...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-13-24
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Diarrhoeal diseases constitute a major public health problem, particularly in the developing world, where the rate of mortality and morbidity is very high. The purpose of this study was to conduct a 2 years and 3 months study in order to determine the prevalence of five enteropathogen diarrheogenic agents in...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-6-17
更新日期：2007-12-28 00:00:00
abstract：BACKGROUND:Escherichia coli is the commonest cause of community and nosocomial urinary tract infection (UTI). Antibiotic treatment is usually empirical relying on susceptibility data from local surveillance studies. We therefore set out to determine levels of resistance to 8 commonly used antimicrobial agents amongst a...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-7-13
更新日期：2008-06-18 00:00:00
abstract：:An 87 -year-old female who was undergoing peritoneal dialysis presented with peritonitis caused by Alcaligenes faecalis and Pantoea agglomerans in consecutive years. With the following report we discuss the importance of these unusual microorganisms in peritoneal dialysis patients. ...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-10-12
更新日期：2011-04-10 00:00:00
abstract：BACKGROUND:This study aimed to evaluate in vitro susceptibility to ceftobiprole of clinical strains identified from prosthetic joint infections (PJIs) compared to that of the associations currently recommended for post-operative empirical antibiotic therapy (PEAT) (vancomycin with either cefepime, third-generation ceph...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-020-00351-5
更新日期：2020-03-21 00:00:00
abstract：BACKGROUND:Aquilaria crassna Pierre ex Lecomte has been traditionally used in Thailand for treatment of infectious diseases such as diarrhoea and skin diseases for a long time. The main objectives of this study were to examine antibacterial activity of the Aquilaria crassna leaf extract against Staphylococcus epidermid...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-12-20
更新日期：2013-08-20 00:00:00
abstract：BACKGROUND:Escherichia coli isolates of equine faecal origin were investigated for antibiotic resistance, resistance genes and their ability to perform horizontal transfer. METHODS:In total, 264 faecal samples were collected from 138 horses in hospital and community livery premises in northwest England, yielding 296 r...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-9-12
更新日期：2010-04-07 00:00:00
abstract：:Stenotrophomonas maltophilia (S. maltophilia) has recently emerged as an important nosocomial pathogen. Treatment of invasive infections caused by this organism is difficult as the bacterium is frequently resistant to a wide range of commonly used antimicrobials. Trimethoprim-sulfamethoxazole (TMP - SXT) is recommende...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-5-23
更新日期：2006-09-18 00:00:00
abstract：BACKGROUND:Central line-associated bloodstream infections (CLABs) have long been associated with excess lengths of stay, increased hospital costs and mortality attributable to them. Different studies from developed countries have shown that practice bundles reduce the incidence of CLAB in intensive care units. However,...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章,多中心研究
doi：10.1186/1476-0711-12-10
更新日期：2013-05-04 00:00:00
abstract：BACKGROUND:Persistence of antibiotic resistant bacteria, including multidrug resistant (MDR) pseudomonads, is an important environmental health problem associated with drinking water distribution systems (DWDS) worldwide. There is paucity of data on the molecular characteristics of antibiotic resistance genes and their...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/s12941-015-0102-4
更新日期：2015-09-02 00:00:00
abstract：:Ebola virus disease (EVD) is a potentially fatal haemorrhagic disease of humans. The last and most serious outbreak of Ebola virus (EBOV) started in December 2013 in West Africa and also affected other continents. Animals such as fruit bats and non-human primates are potential sources of EBOV. This review highlights t...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章,评审
doi：10.1186/s12941-015-0089-x
更新日期：2015-05-28 00:00:00
abstract：BACKGROUND:Helicobacter pylori has been strongly associated with chronic gastritis, peptic and duodenal ulcers, and it is a risk factor for gastric cancer. Three major virulence factors of H. pylori have been described: the vacuolating toxin (VacA), the cytotoxin-associated gene product (CagA) and the adhesion protein ...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-8-14
更新日期：2009-04-30 00:00:00
abstract：BACKGROUND:In 2002 we investigated an outbreak comprising 231 patients in Norway, caused by Pseudomonas aeruginosa and linked to the use of contaminated mouth swabs called Dent-O-Sept. Here we describe the extent of contamination of the swabs, and identify critical points in the production process that made the contami...
journal_title：Annals of clinical microbiology and antimicrobials
pub_type： 杂志文章
doi：10.1186/1476-0711-6-3
更新日期：2007-03-13 00:00:00
