Abstract：
:Hereditary spherocytosis (HS), a familial defect involving red blood cell (RBC) membrane proteins, is associated with reduced deformability, increased fragility, and progressive destruction of spherical cells. The present study focuses on three subjects of a family showing a history of repeated episodes of lethargy and pallor of unknown etiology. All patients displayed reticulocytosis and spherocytosis and one of them had anemia and splenomegaly. The patients underwent screening tests to rule in/out possible underlying disorders, and deficiency/dysfunction of RBC membrane proteins was suspected. Definitive diagnosis can be made on the basis of membrane protein analysis by quantitative sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Interestingly, all patients showed marked decrease in the protein 4.2 expression and therefore, HS was confirmed. This case report highlights the simultaneous occurrence of protein 4.2-dependent "typical" and "atypical" HS in a family and serves as a reminder to clinicians to consider RBC membrane disorders in patients presenting with suspicious and unexplained clinical signs.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Vahidi R,Sheikhrezaei Z,Ameri Z,Khaleghi M,Farsinejad Asubject
Has Abstractpub_date
2020-03-01 00:00:00pages
207-210issue
3eissn
1029-2977issn
1735-3947pii
S1029-2977-23(03)207-0journal_volume
23pub_type
杂志文章abstract：:Systemic therapy is one of the cornerstones of cancer treatment. In 1972, following representations by American Society of Clinical Oncology (ASCO), the American Board of Internal Medicine (ABIM) recognized medical oncology as a new subspecialty of internal medicine. Subspecialty of Hematology and Medical Oncology was...
journal_title：Archives of Iranian medicine
pub_type： 历史文章,杂志文章
doi：0151811/AIM.0013
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to investigate the association between Trp719Arg (rs20455) and Coronary Heart Disease (CHD), and also Coronary Heart Disease reduction in individuals with this SNP during statin therapy in southern Iran. It has been shown that rs20455, which could affect the function of kinesin ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151810/AIM.008
更新日期：2015-10-01 00:00:00
abstract：BACKGROUND:The Consolidated Standards for Reporting of Trials (CONSORT) statement is a device to standardize reporting and improve the quality of controlled trials. The aim of this study is to determine the quality of controlled clinical trial reports by national peer-reviewed journals in Iran. METHODS:In a cross-sect...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013161/AIM.007
更新日期：2013-01-01 00:00:00
abstract：:Esophageal cancer (EC) is the 8th most common cancer and the 6th most frequent cause of cancer mortality worldwide. Esophageal squamous cell carcinoma (ESCC) is the most common type of EC. Exposure to polycyclic aromatic hydrocarbons (PAHs) has been suggested as a risk factor for developing ESCC. In this paper we will...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,评审
doi：0121511/AIM.0013
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Previous studies reported the association between dietary patterns and prevalence of diabetes, cardiovascular disease and other chronic disease. However, there are no studies reporting major dietary patterns in patients awaiting coronary artery bypass graft surgery (CABG). The aim of this study was to obtain...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161907/AIM.005
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Osteoporosis has been frequently reported in patients with inflammatory bowel diseases, especially Crohn's disease. METHODS:All consecutive Crohn's disease patients who attended the GI Clinics at Shariati Hospital, Tehran, Iran, from 2004 to 2007 were evaluated. A BMD-DEXA assessment was performed for all p...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2009-11-01 00:00:00
abstract：:Actinomycotic infections are known to be associated with difficulties in making the diagnosis and treatment. Actinomycosis of the tongue is rare and of great importance, not only because it can mimic many other diseases, but also because the tongue itself has some histophysiologic features that make it resistant to in...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：BACKGROUND:The current WHO classification of hematologic malignancies defines distinct entities of myeloid disorders based on the presence of recurrent cytogenetic abnormalities. Diagnostic clonal chromosomal abnormalities provide important prognostic information and are among the most important factors in predicting i...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013168/AIM.005
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:The present study was conducted to determine the health-related quality of life in patients living with human immunodeficiency virus or suffering from acquired immune deficiency syndrome (HIV/AIDS), referred to Behavioral Diseases Consultation Center in west of Tehran, Iran. METHODS:This cross-sectional stu...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：BACKGROUND:Non-antifungal drugs appear promising in treatment of opportunistic infections of Candida spp. that are often resistant to current antifungals. METHODS:The broth macrodilution method (NCCLS M27-P document) was used to compare the antifungal activity of trifluoperazine, propranolol, and lansoprazole with tha...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：012151/AIM.009
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Functional foods are extensively studied for their cancer preventive effects. In the present study, we compared the anti-cancer activity of aqueous extracts of three species of mushrooms including: Pleurotus ostreatus (PAE), Auricularia polytricha (AAE) and Macrolepiota procera (MAE) on COLO-205 cells. METH...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151805/AIM.006
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Human rotavirus has now been established as the most important cause of childhood gastroenteritis worldwide. The RNA genomic electrophoretic diversity of group A rotavirus strains in Tehran, Iran, during April 2002 through March 2005, was investigated in 1250 stool specimens. METHODS:Stool samples were obta...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：:Evans syndrome is a rare syndrome associated with the simultaneous or sequential development of autoimmune hemolytic anemia (AIHA) and idiopathic thrombocytopenic purpura (ITP). Furthermore, acute kidney injury (AKI) is a syndrome characterized by the rapid loss of kidney excretory function and is most often secondary...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:The childhood obesity epidemic is one of the most serious global health challenges, and many relevant policies have been designed and implemented. Regarding health equity policy-making, it is important to adopt proper interventional strategies, including childhood obesity policies. The purpose of this study ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Helicobacter pylori isolates from 84 adults and 51 children were assessed during the period of 2001 through 2004 to find out whether their susceptibilities to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone differ between the two groups or have changed compared with the results fro...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：:The coronavirus infection is an evolving pandemic with high morbidity and mortality, especially in people with comorbidities. The case fatality rate (CFR) is 9.2% in the presence of diabetes, while it is 1.4% in those without any comorbidity. Diabetes is a prevalent disease globally; hence, healthcare professionals ar...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：10.34172/aim.2020.61
更新日期：2020-08-01 00:00:00
abstract：:Synchronous development of gastrointestinal stromal tumors with other tumors in the digestive tract is relatively rare, and often occurs in the stomach. We report a 76-year-old woman, who suffered from the exceedingly rare synchronous development of small intestinal stromal tumor and cecal adenocarcinoma. The patient ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：:Following the Islamic Revolution of 1979 in Iran, the trend of migration of physicians from the country continued. The total number of Iranian physicians migrated to the United States (US) increased from 1625 before revolution in 1974, to 5045 in 2010, thirty years post-revolution. The percentage of medical graduates ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0131610/AIM.008
更新日期：2013-10-01 00:00:00
abstract：:Adrenal cysts are rare lesions which are usually nonfunctional and asymptomatic. Adrenal pseudocysts do not have epithelial linings and account for about 40% of adrenal cysts. We report a case of giant adrenal pseudocyst in a 32 year old woman presenting with flank pain who had undergone surgical excision. ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0131612/AIM.0012
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Although serological screening tests for blood-borne hepatitis viruses have effectively reduced the risk of HBV transmission through transfusion of infected blood, there is still a possibility that infected blood units from occult carriers being released into the blood supply. The aim of this study was to de...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：014172/AIM.004
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Cardiovascular disease (CVD) is among the most common causes of mortality in all populations. Nonalcoholic steatohepatitis is a common finding in patients with CVD. Prevention of CVD in individual patients typically requires periodic clinical evaluation, as well as diagnosis and management of risk factors su...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：015188/AIM.009
更新日期：2015-08-01 00:00:00
abstract：:This brief review presents Razi's concepts of bone and joint disorders. Razi differentiated between ligaments, tendons, and nerves and recognized the role of the brain, spinal cord, and peripheral nervous system in the perception of senses and voluntary movements. He described paralysis and loss of sensation following...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：10.34172/aim.2020.74
更新日期：2020-09-01 00:00:00
abstract：:The history of early attempts of blood transfusion in Iran traces back to the 1940s; however, around three decades later in 1974, the Iranian National Blood Transfusion Service (Sazeman-e Melli-e Enteqal-e Khun-e Iran) was founded by the outstanding hematologist, Professor Fereydoun Ala. The main goals of this central...
journal_title：Archives of Iranian medicine
pub_type： 传,历史文章,杂志文章
doi：015186/AIM.0016
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:HIV infection affects all body organs including kidney. Since the frequency of HIV-related renal disorders is unknown in Iran and the number of HIV-infected patients is increasing, this study was conducted for the first time in Iran to assess the frequency of electrolyte imbalance, renal failure, and protein...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：07103/AIM.0010
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Our aim was to determine the association between age at menarche (AAM) and breast cancer adjusted for recall bias (misclassification) in AAM. METHODS:We have used data provided from a case-control study conducted in Iran from 2005 to 2009. The cases and controls were frequency matched based on 5-year age gr...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2019-02-01 00:00:00
abstract：:Intravenous drug abuse is an increasing social and health problem. Repeated injuries to the veins, injection of some types of insoluble substances, and needle sharing habits result in various complications. Increasing incidence of major vascular complications has been reported worldwide. The objective of this study wa...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：07104/AIM.0018
更新日期：2007-10-01 00:00:00
abstract：:Vitamin D is a pro-hormone that plays an important role in body calcium regulation. Vitamin D toxicity occurs rarely due to its wide therapeutic index. A 38-year-old Iranian man was admitted to our hospital with a diagnosis of vitamin D toxicity. Laboratory test revealed hypercalcemia and elevated 25-hydroxyvitamin D ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161908/AIM.0013
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVES:Studies on gastric mucosal histological findings among first degree relatives (FDR) of gastric cancer (GC) patients are scarce. The aim is to evaluate the topography and the severity of gastritis among FDR of GC patients. DESIGN:A total of 989 subjects who were FDR of GC patients, ages 40-65 years underwent...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：010136/AIM.004
更新日期：2010-11-01 00:00:00
abstract：UNLABELLED: BACKGROUND:Potato, a high- glycemic index (GI) food, is one of the most widely used starchy foods worldwide. Previous studies on the association of dietary intakes with stroke have mostly focused on the dietary GI and there is no information regarding the association between potato consumption and risk of...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013163/AIM.009
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:In the present study, the effect of dextromethorphan on antinociception and tolerance induced by water swim-stress in the formalin test was investigated. METHODS:Swim-stress at 8 masculineC induces antinociception in both phases of the formalin test. Intraperitoneal administration of dextromethorphan (60 mg...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：08113/AIM.0010
更新日期：2008-05-01 00:00:00
