Abstract:
OBJECTIVES:Studies on gastric mucosal histological findings among first degree relatives (FDR) of gastric cancer (GC) patients are scarce. The aim is to evaluate the topography and the severity of gastritis among FDR of GC patients. DESIGN:A total of 989 subjects who were FDR of GC patients, ages 40-65 years underwent gastroscopies. When no gross lesion was found, five specimens were evaluated according to the Sydney Classification and one for urease testing in order to determine the type of gastritis and its severity. RESULTS:Of the 989 subjects, 107 had significant lesions, including two with GC and one with esophageal cancer. The 864 subjects who had complete morphological data taken from five gastric areas (two from the antrum and three from the corpus) comprised 419 males (mean age 48.5±7 years) and 445 females (mean age 47±6.4 years). The H. pylori rate was 76.6%. Normal mucosa was seen in 6.9%, antrum-restricted gastritis in 7.4%, antrum-predominant gastritis in 63.5% and corpus-predominant gastritis in 20% (both had >80% H. pylori infection) and corpus-restricted gastritis in 2%. More atrophy was seen in the antrum and corpus of FDR females than males. The severity did not differ between those with one or more GC patients' relatives. Forty-nine percent of FDR had atrophy and 9.4% intestinal metaplasia (IM) in the corpus. After the age of 40, there was progression of intestinal metaplasia from 12.2 to 27.3% in the antrum and from 6.7% to 26.2% in the corpus during two decades. No high grade dysplasia was found in this mid-age population. CONCLUSION:Only one-fifth of FDR have H. pylori-induced corpus-predominant gastritis who are at risk for cancer and suitable for eradication. Corpus-restricted gastritis is a rare disease in this area.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Zendehdel N,Massarrat S,Sheykholeslami A,Rakhshani N,Saeidi S,Rafiee R,Nobakht H,Tabib SM,Saliminejhad M,Dooghaie Moghadam M,Nasiri J,Azimi K,Fakhar R,Babaei M,Didehvar R,Mohammadi N,Tavazoee M,Malekzadeh Rdoi
010136/AIM.004subject
Has Abstractpub_date
2010-11-01 00:00:00pages
469-75issue
6eissn
1029-2977issn
1735-3947pii
004journal_volume
13pub_type
杂志文章abstract:BACKGROUND:Estrogen is the major sex steroid affecting the growth, remodeling, and homeostasis of the female skeleton. Estrogen loss in postmenopausal women leads to osteoporosis. The aim of this study was to evaluate the early and long- term effects of estrogen loss on bones, tendons, muscles, and menisci in ovariecto...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013165/AIM.006
更新日期:2013-05-01 00:00:00
abstract::Septic arthritis is a fearful condition because of its mortality and the potentially late sequels on immature skeleton including limb shortening, osteomyelitis, destruction of joint surface, severe limitation of motion, and dislocation.This study was performed to reveal the final outcome of our patients and find out t...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Wrong beliefs about risky actions such as sunbathing and tanning are common due to media advertisements or general lack of knowledge. This work has focused on the knowledge and attitude of a group of citizens in Tehran, Iran and the protective actions they take regarding undesirable effects of the sun. M...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:011142/AIM.0011
更新日期:2011-03-01 00:00:00
abstract::Synchronous development of gastrointestinal stromal tumors with other tumors in the digestive tract is relatively rare, and often occurs in the stomach. We report a 76-year-old woman, who suffered from the exceedingly rare synchronous development of small intestinal stromal tumor and cecal adenocarcinoma. The patient ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Human rotavirus has now been established as the most important cause of childhood gastroenteritis worldwide. The RNA genomic electrophoretic diversity of group A rotavirus strains in Tehran, Iran, during April 2002 through March 2005, was investigated in 1250 stool specimens. METHODS:Stool samples were obta...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:HIV infection affects all body organs including kidney. Since the frequency of HIV-related renal disorders is unknown in Iran and the number of HIV-infected patients is increasing, this study was conducted for the first time in Iran to assess the frequency of electrolyte imbalance, renal failure, and protein...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:07103/AIM.0010
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:Transfusion of packed red blood cells (pRBC) with appropriate indications is not only important for patient safety and well-being but is also crucial for proper utilization of resources and health care-related cost reduction. We aimed to investigate the clinical appropriateness of blood transfusion in Shar...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0172002/AIM.004
更新日期:2017-02-01 00:00:00
abstract::Despite all the problems caused by the imposed war, sanctions and accidents after the Islamic Revolution, materializing primary health care (PHC) in Iran through establishing the National Health Network (NHN) has had substantial gains. Many health indicators in Iran have undergone significant changes. As an example, t...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The current WHO classification of hematologic malignancies defines distinct entities of myeloid disorders based on the presence of recurrent cytogenetic abnormalities. Diagnostic clonal chromosomal abnormalities provide important prognostic information and are among the most important factors in predicting i...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:013168/AIM.005
更新日期:2013-08-01 00:00:00
abstract::Systemic therapy is one of the cornerstones of cancer treatment. In 1972, following representations by American Society of Clinical Oncology (ASCO), the American Board of Internal Medicine (ABIM) recognized medical oncology as a new subspecialty of internal medicine. Subspecialty of Hematology and Medical Oncology was...
journal_title:Archives of Iranian medicine
pub_type: 历史文章,杂志文章
doi:0151811/AIM.0013
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Functional foods are extensively studied for their cancer preventive effects. In the present study, we compared the anti-cancer activity of aqueous extracts of three species of mushrooms including: Pleurotus ostreatus (PAE), Auricularia polytricha (AAE) and Macrolepiota procera (MAE) on COLO-205 cells. METH...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151805/AIM.006
更新日期:2015-05-01 00:00:00
abstract::Acute hemorrhagic edema of infancy is a distinctive, cutaneous small vessel leukocytoclastic vasculitis of young children with dramatic characteristic skin findings. It is characterized by low- grade fever, erythematous edema, and purpuric lesions mainly on the face and extremities. Visceral involvement is uncommon, a...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:08111/AIM.0019
更新日期:2008-01-01 00:00:00
abstract::On January 23, 2020, the Chinese government announced the city lockdown of Wuhan. Since then, there have been controversial debates among experts about the efficacy of mass quarantine, the oldest and probably one of the most effective methods for controlling infectious disease outbreaks. The impact of health policymak...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:10.34172/aim.2020.08
更新日期:2020-04-01 00:00:00
abstract::Following the Islamic Revolution of 1979 in Iran, the trend of migration of physicians from the country continued. The total number of Iranian physicians migrated to the United States (US) increased from 1625 before revolution in 1974, to 5045 in 2010, thirty years post-revolution. The percentage of medical graduates ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0131610/AIM.008
更新日期:2013-10-01 00:00:00
abstract::The purpose of this article is to present the CT features in five cases of pathologically verified Inferior vena cava (IVC) leiomyosarcoma. In this retrospective analysis, we reviewed CT features in 5 cases of clinicopathologically confirmed IVC leiomyosarcoma with respect to its location (infra renal, trans renal, su...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0141705/AIM.0014
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Oxidative stress is involved in the pathophysiology of diabetes mellitus. METHODS:In the present study, 68 patients with type 2 diabetes mellitus and 31 clinically healthy individuals were evaluated. The patients were divided into two groups. Group 1 included 29 patients without diabetic complications and g...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:In Iran, zoonotic and anthroponotic cutaneous leishmaniasis (CL) are caused by Leishmania major and L. tropica respectively. Despite extensive studies, no effective therapies have ever been reported for CL. The main objective of this research was to determine and compare the three different protocols for tre...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:10.34172/aim.2020.98
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:This study was conducted to evaluate the hematological effects of umbilical cord clamp timing and delivery type in term infants 48 hours after birth in Imam Hossein Hospital, Tehran, Iran. METHOD:From Oct 2007 - March 2008, 100 mother-infant eligible pairs were selected and divided by cord clamp timing (< or...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:010135/AIM.0010
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION:Successful isolation of mesenchymal stem cells from waste tissues might be extremely promising for developing stem cell-based therapies. This study aimed to explore whether cells retrieved from teeth extracted due to advanced periodontal disease present mesenchymal stem cell-like properties. METHODS:Pulp ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:015184/AIM.004
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Preventing violence is important especially in the Middle East, where many countries are struggling with violence. Knowing the affecting factors could help public policy makers to decrease violence level. Thus, this study is aimed to analyze health and other socio-economic factors that could affect interpers...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the association between Trp719Arg (rs20455) and Coronary Heart Disease (CHD), and also Coronary Heart Disease reduction in individuals with this SNP during statin therapy in southern Iran. It has been shown that rs20455, which could affect the function of kinesin ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0151810/AIM.008
更新日期:2015-10-01 00:00:00
abstract:INTRODUCTION:This research aims to determine the mental health status of population aged 15 and over in the province of Chaharmahal and Bakhtiari in 2015. METHODS:The statistical population of this cross-sectional field survey consisted of residents of urban and rural areas of Chaharmahal and Bakhtiari in Iran. An est...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Psoriasis (Ps) is a chronic skin disease that can lead to negative impacts on quality of life (QoL) because of diseaserelated comorbidities. We aimed to investigate the risk of obstructive sleep apnea syndrome (OSAS) in patients with Ps. METHODS:Fifty-seven patients with Ps were included in this study. The ...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Because resistance to antifungal drugs is seen in patients, susceptibility testing of these drugs aids in choosing the appropriate drug and respective epidemiology. This study has investigated and compared susceptibility patterns of the Aspergillus species isolated from patients by the Clinical and Laborator...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:012157/AIM.0011
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Previous studies reported the association between dietary patterns and prevalence of diabetes, cardiovascular disease and other chronic disease. However, there are no studies reporting major dietary patterns in patients awaiting coronary artery bypass graft surgery (CABG). The aim of this study was to obtain...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0161907/AIM.005
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:we aimed to recap and highlight the major results of the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 by mortality and morbidity to clarify the current health priorities and challenges in Iran. METHODS:We estimated Iran's mortality and burden of 289 diseases with 67 risk factors and 1160...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0141705/AIM.004
更新日期:2014-05-01 00:00:00
abstract::Effective prevention and early diagnostic strategies are the most important public health interventions in gastric cancer, which remains a common malignancy worldwide. Preventive strategies require identification and understanding of environmental risk factors that lead to carcinogenesis. Helicobacter pylori (H. pylor...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章,评审
doi:013166/AIM.0010
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:This study aims to compare the dietary and physical activity (PA) habits in a nationally representative sample of Iranian children and adolescents based on their family and regional socioeconomic status (SES). METHOD:This nationwide study was conducted on 14,880 students, aged 6-18 years, and one of their p...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0161908/AIM.003
更新日期:2016-08-01 00:00:00
abstract::As there is a significant number of Iranian immigrant and illegal refugees living in marginal areas of large cities that might induce immunization gap in these areas. The aim of this study was to provide reliable information on vaccination status of these people. A cross sectional study was conducted on children 24-4...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:0141710/AIM.0011
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Patients with chronic kidney disease (CKD) have specific dietary needs due to recommended dietary restrictions. However, there is no specific index for evaluating the quality of diet in patients with CKD. OBJECTIVE: To define and compare three specific diet quality indices in patients with CKD. METHODS:Tw...
journal_title:Archives of Iranian medicine
pub_type: 杂志文章
doi:
更新日期:2017-08-01 00:00:00