Abstract：
:The close proximity of esophagus to the left atrial posterior wall predisposes esophagus to thermal injury during catheter ablation for atrial fibrillation (AF). In this retrospective study, we aimed to investigate risk factors of esophageal injury (EI) caused by catheter ablation for AF. Patients who underwent first-time AF ablation from July 2013 to June 2018 were included. The esophagus was visualized by oral soluble contrast during ablation for all patients and a subset of patients were selected to undergo endoscopic ultrasonography (EUS) to estimate EI post ablation. Degree of EI was categorized as Kansas City classification: type 1: erythema; type 2: ulcers (2a: superficial ulcers; 2b: deep ulcers); type 3: perforation (3a: perforation without communication with the atria; 3b: atrioesophageal fistula [AEF]). Of 3,852 patients, 236 patients (61.5 ± 9.7 years; male, 69%) received EUS (EUS group) and 3616 (63.2 ± 10.9 years; male, 61.1%) without EUS (No-EUS group). In EUS group, EI occurred in 63 patients (type 1 EI in 35 and type 2 EI in 28), and no type 3 EI was observed during follow up. In a multivariable logistic regression analysis, an overlap between the ablation lesion and esophagus was an independent predictor of EI (odds ratio, 21.2; 95% CI: 6.23-72.0; P < 0.001). In No-EUS group, esophagopericardial fistula (EPF; n = 3,0.08%) or AEF (n = 2,0.06%) was diagnosed 4-37 days after ablation. In 3 EPF patients, 2 completely recovered with conservative management and 1 died. Two AEF patients died. Ablation at the vicinity of the esophagus predicts risk of EI. EUS post ablation may prevent the progression of EI and should be considered in management of EI. It remains challenging to identify patients with high risk of EI.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhang P,Zhang YY,Ye Q,Jiang RH,Liu Q,Ye Y,Wu JG,Sheng X,Fu GS,Cha YM,Jiang CYdoi
10.1038/s41598-020-59539-6subject
Has Abstractpub_date
2020-02-17 00:00:00pages
2751issue
1issn
2045-2322pii
10.1038/s41598-020-59539-6journal_volume
10pub_type
杂志文章abstract：:Phasins or PhaPs are a group of amphiphilic proteins that are found attached to the surface of microbial polyhydroxyalkanoate (PHA) granules. They have both structural and regulatory functions and can affect intracellular PHA accumulation and mediate protein folding. The molecular basis for the diverse functions of th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39424
更新日期：2016-12-23 00:00:00
abstract：:The heterogeneity of metabolic reactions leads to a non-uniform distribution of temperature in different parts of the living cell. The demand to study normal functioning and pathological abnormalities of cellular processes requires the development of new visualization methods. Previously, we have shown that the 35-kDa...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45421-7
更新日期：2019-06-20 00:00:00
abstract：:Transposable elements (TEs) are genomic sequences that can move, multiply, and often form sizable fractions of vertebrate genomes. Fish belong to a unique group of vertebrates, since their karyotypes and genome sizes are more diverse and complex, with probably higher diversity and evolution specificity of TE. To inves...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51888-1
更新日期：2019-10-28 00:00:00
abstract：:The variation in mortality-to-incidence ratios (MIRs) among countries reflects the clinical outcomes and the available interventions for colorectal cancer treatments. The association between MIR of prostate cancer and cancer care disparities among countries is an interesting issue that is rarely investigated. For the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40003
更新日期：2017-01-04 00:00:00
abstract：:Although various function of chemerin have been suggested, its physiological role remains to be elucidated. Here we show that chemerin-deficient mice are glucose intolerant irrespective of exhibiting reduced macrophage accumulation in adipose tissue. The glucose intolerance was mainly due to increased hepatic glucose ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00123
更新日期：2011-01-01 00:00:00
abstract：:Biofertilizer production and application for sustainable agriculture is already a reality. The methods for biofertilizers delivery in crop fields are diverse. Although foliar spray is gaining wide acceptance, little is known about the influence that the biochemical features of leaves have on the microbial colonization...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65314-4
更新日期：2020-05-21 00:00:00
abstract：:Auxetic foams continue to interest researchers owing to their unique and enhanced properties. Existing studies attest to the importance of fabrication mechanisms and parameters. However, disparity in thermo-mechanical parameters has left much debate as to which factors dominate fabrication output quality. This paper p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75298-w
更新日期：2020-10-27 00:00:00
abstract：:Based on the electrical characteristic detection technology, the quantitative prediction models of sensory score and physical and chemical quality Index (theaflavins, thearubigins, and theabrownins) were established by using the fermented products of Congou black tea as the research object. The variation law of electr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58637-9
更新日期：2020-01-31 00:00:00
abstract：:Optical imaging and photolithography promise broad applications in nano-electronics, metrologies, and single-molecule biology. Light diffraction however sets a fundamental limit on optical resolution, and it poses a critical challenge to the down-scaling of nano-scale manufacturing. Surface plasmons have been used to ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00175
更新日期：2011-01-01 00:00:00
abstract：:Translational motion of neurotransmitter receptors is key for determining receptor number at the synapse and hence, synaptic efficacy. We combine live-cell STORM superresolution microscopy of nicotinic acetylcholine receptor (nAChR) with single-particle tracking, mean-squared displacement (MSD), turning angle, ergodic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30384-y
更新日期：2018-08-10 00:00:00
abstract：:In recent years, the topic of noise in the sea and its effects on marine mammals has attracted considerable attention from both the scientific community and the general public. Since marine mammals rely heavily on acoustics as a primary means of communicating, navigating, and foraging in the ocean, any change in their...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00437
更新日期：2012-01-01 00:00:00
abstract：:Alzheimer's disease is characterized by neuronal loss and cerebral accumulation of amyloid-β protein (Aβ) and lowering the generation of Aβ is a pivotal approach in the strategy of Alzheimer's disease treatment. Midlife hypertension is a major risk factor for the future onset of sporadic Alzheimer's disease and the us...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12059
更新日期：2015-07-08 00:00:00
abstract：:An increased breast cancer risk during adulthood has been linked to estrogen exposure during fetal life. However, the impossibility of removing estrogens from the feto-maternal unit has hindered the testing of estrogen's direct effect on mammary gland organogenesis. To overcome this limitation, we developed an ex vivo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40806
更新日期：2017-01-19 00:00:00
abstract：:Podocyte loss is the initial event in the development of glomerulosclerosis, the structural hallmark of progressive proteinuric nephropathies. Understanding mechanisms underlying glomerular injury is the key challenge for identifying novel therapeutic targets. In mice with protein-overload induced by bovine serum albu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep28445
更新日期：2016-06-27 00:00:00
abstract：:Humans interact with the oceans in diverse and profound ways. The scope, magnitude, footprint and ultimate cumulative impacts of human activities can threaten ocean ecosystems and have changed over time, resulting in new challenges and threats to marine ecosystems. A fundamental gap in understanding how humanity is af...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47201-9
更新日期：2019-08-12 00:00:00
abstract：:Recognition of the potential for vegetated coastal ecosystems to store and sequester carbon has led to their increasing inclusion into global carbon budgets and carbon offset schemes. However, kelp forests have been overlooked in evaluations of this 'blue carbon', which have been limited to tidal marshes, mangrove for...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69258-7
更新日期：2020-07-23 00:00:00
abstract：:Cell and animal studies have demonstrated that circadian rhythm is governed by autonomous rhythmicity of clock genes. Although disturbances in circadian rhythm have been implicated in metabolic disease development, it remains unknown whether muscle circadian rhythm is altered in human models of type 2 diabetes. Here w...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35047
更新日期：2016-10-19 00:00:00
abstract：:Assessment of intraventricular pressure gradients (IVPG) using color Doppler M-mode echocardiography has gained increasing interest in the evaluation of cardiac function. However, standardized analysis tools for IVPG quantification are missing. We aimed to evaluate the feasibility, the test-retest observer reproducibi...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-020-64059-4
更新日期：2020-04-28 00:00:00
abstract：:To assess whether the immunosuppressive effects of atorvastatin outweigh its antibacterial ones in an infection, mice were infected with Escherichia coli and administered atorvastatin; survival rates were then monitored. Mice treated with atorvastatin post-infection showed a remarkable decrease in their survival rate....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48282-2
更新日期：2019-08-12 00:00:00
abstract：:Electrophysiological field potential dynamics have been widely used to investigate brain functions and related psychiatric disorders. Considering recent demand for its applicability to freely moving subjects, especially for animals in a group and socially interacting with each other, here we propose a new method based...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43897-x
更新日期：2019-05-16 00:00:00
abstract：:The metal-to-insulator transition (MIT) closest to room temperature of 68-70 °C as shown by vanadium oxide (VO2), compared with other transition metal oxides, makes it a potential candidate for smart window coating. We have successfully fabricated a potential smart window device after the optimum design of a multilaye...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58698-w
更新日期：2020-02-04 00:00:00
abstract：:We report a strategy to achieve a discrete cage molecule featuring a high level of structural hierarchy through a multiple-assembly process. A cobalt (Co) supramolecular triple-stranded helicate (Co-TSH)-based discrete molecular cage (1) is successfully synthesized and fully characterized. The solid-state structure of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep43448
更新日期：2017-03-06 00:00:00
abstract：:Solar-driven photoelectrochemical water splitting (PEC-WS) using semiconductor photoelectrodes is considered a promising solution for sustainable, renewable, clean, safe and alternative energy sources such as hydrogen. Here, we report the synthesis and characterization of a novel heterostructure MoS2/GaN to be used as...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56807-y
更新日期：2019-12-27 00:00:00
abstract：:Molecular dynamics (MD) simulations lasting 500 ns were performed in explicit water to investigate the effect of polarization on the binding of ligands to human α-thrombin based on the standard nonpolarizable AMBER force field and the quantum-derived polarized protein-specific charge (PPC). The PPC includes the electr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31488
更新日期：2016-08-10 00:00:00
abstract：:CLN3 mutations cause the fatal neurodegenerative disorder, CLN3 Batten disease. The Cln3-/- mouse model displays characteristic features of the human disease including motor deficits. When mice received acidified drinking water (pH 2.5-2.9) instead of normal tap water (pH 8.4) for several generations, the motor skills...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51488-z
更新日期：2019-10-18 00:00:00
abstract：:Since the production of ferromagnetic graphene as an extremely important matter in spintronics has made a revolution in future technology, a great deal of efforts has recently been done to reach a simple and cost-effective method. Up to now, controlling the magnetic properties at extremely low temperature have been in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78262-w
更新日期：2020-12-07 00:00:00
abstract：:Orexins are originally characterized as orexigenic hypothalamic neuropeptides in mammals. Subsequent studies found orexin to be expressed and perform pleiotropic functions in multiple tissues in mammals. In avian (non-mammalian) species, however, orexin seemed to not affect feeding behavior and its physiological roles...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76329-2
更新日期：2020-11-05 00:00:00
abstract：:Most complex systems are intrinsically dynamic in nature. The evolution of a dynamic complex system is typically represented as a sequence of snapshots, where each snapshot describes the configuration of the system at a particular instant of time. This is often done by using constant intervals but a better approach wo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep39713
更新日期：2016-12-22 00:00:00
abstract：:Plants are continuously exposed to myriad pathogen stresses. However, the molecular mechanisms by which these stress signals are perceived and transduced are poorly understood. In this study, the maize gene GRMZM2G315431 was identified to be highly inducible by Rhizoctonia solani infection, suggesting that the promote...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep42059
更新日期：2017-02-06 00:00:00
abstract：:Oscillatory media can exhibit the coexistence of synchronized and desynchronized regions, so-called chimera states, for uniform parameters and symmetrical coupling. In a phase-balanced chimera state, where the totals of synchronized and desynchronized regions, respectively, are of the same size, the symmetry of the sy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09883
更新日期：2015-04-30 00:00:00
