Characteristics of Atrial Fibrillation Patients Suffering Esophageal Injury Caused by Ablation for Atrial Fibrillation.


:The close proximity of esophagus to the left atrial posterior wall predisposes esophagus to thermal injury during catheter ablation for atrial fibrillation (AF). In this retrospective study, we aimed to investigate risk factors of esophageal injury (EI) caused by catheter ablation for AF. Patients who underwent first-time AF ablation from July 2013 to June 2018 were included. The esophagus was visualized by oral soluble contrast during ablation for all patients and a subset of patients were selected to undergo endoscopic ultrasonography (EUS) to estimate EI post ablation. Degree of EI was categorized as Kansas City classification: type 1: erythema; type 2: ulcers (2a: superficial ulcers; 2b: deep ulcers); type 3: perforation (3a: perforation without communication with the atria; 3b: atrioesophageal fistula [AEF]). Of 3,852 patients, 236 patients (61.5 ± 9.7 years; male, 69%) received EUS (EUS group) and 3616 (63.2 ± 10.9 years; male, 61.1%) without EUS (No-EUS group). In EUS group, EI occurred in 63 patients (type 1 EI in 35 and type 2 EI in 28), and no type 3 EI was observed during follow up. In a multivariable logistic regression analysis, an overlap between the ablation lesion and esophagus was an independent predictor of EI (odds ratio, 21.2; 95% CI: 6.23-72.0; P < 0.001). In No-EUS group, esophagopericardial fistula (EPF; n = 3,0.08%) or AEF (n = 2,0.06%) was diagnosed 4-37 days after ablation. In 3 EPF patients, 2 completely recovered with conservative management and 1 died. Two AEF patients died. Ablation at the vicinity of the esophagus predicts risk of EI. EUS post ablation may prevent the progression of EI and should be considered in management of EI. It remains challenging to identify patients with high risk of EI.


Sci Rep


Scientific reports


Zhang P,Zhang YY,Ye Q,Jiang RH,Liu Q,Ye Y,Wu JG,Sheng X,Fu GS,Cha YM,Jiang CY




Has Abstract


2020-02-17 00:00:00












  • Utilisation of Design of Experiments Approach to Optimise Supercritical Fluid Extraction of Medicinal Cannabis.

    abstract::Carbon dioxide supercritical fluid extraction (CO2 SFE) is a clean and cost-effective method of extracting cannabinoids from cannabis. Using design of experiment methodologies an optimised protocol for extraction of medicinal cannabis bud material (population of mixed plants, combined THC:CBD approximately 1:1.5) was ...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Rochfort S,Isbel A,Ezernieks V,Elkins A,Vincent D,Deseo MA,Spangenberg GC

    更新日期:2020-06-04 00:00:00

  • A genetic variant of miR-148a binding site in the SCRN1 3'-UTR is associated with susceptibility and prognosis of gastric cancer.

    abstract::Single nucleotide polymorphisms (SNPs) in the 3'-untranslated regions targeted by putative mircoRNA can change its binding strength, affecting the susceptibility and prognosis of cancer. We aimed to investigate the associations between SNPs within miR-148a binding sites and gastric cancer (GC) risk and prognosis. Usin...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Song P,Zhu H,Zhang D,Chu H,Wu D,Kang M,Wang M,Gong W,Zhou J,Zhang Z,Zhao Q

    更新日期:2014-11-17 00:00:00

  • Comparative transcriptome analysis of Eogammarus possjeticus at different hydrostatic pressure and temperature exposures.

    abstract::Hydrostatic pressure is an important environmental factor affecting the vertical distribution of marine organisms. Laboratory-based studies have shown that many extant shallow-water marine benthic invertebrates can tolerate hydrostatic pressure outside their known natural distributions. However, only a few studies hav...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Chen J,Liu H,Cai S,Zhang H

    更新日期:2019-03-05 00:00:00

  • Molecular classification based on apomorphic amino acids (Arthropoda, Hexapoda): Integrative taxonomy in the era of phylogenomics.

    abstract::With the great development of sequencing technologies and systematic methods, our understanding of evolutionary relationships at deeper levels within the tree of life has greatly improved over the last decade. However, the current taxonomic methodology is insufficient to describe the growing levels of diversity in bot...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Wu HY,Wang YH,Xie Q,Ke YL,Bu WJ

    更新日期:2016-06-17 00:00:00

  • Differential attraction and repulsion of Staphylococcus aureus and Pseudomonas aeruginosa on molecularly smooth titanium films.

    abstract::Magnetron sputtering techniques were used to prepare molecularly smooth titanium thin films possessing an average roughness between 0.18 nm and 0.52 nm over 5 μm × 5 μm AFM scanning areas. Films with an average roughness of 0.52 nm or lower were found to restrict the extent of P. aeruginosa cell attachment, with less ...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Ivanova EP,Truong VK,Webb HK,Baulin VA,Wang JY,Mohammodi N,Wang F,Fluke C,Crawford RJ

    更新日期:2011-01-01 00:00:00

  • Heart rate variability as an independent predictor for 8-year mortality among chronic hemodialysis patients.

    abstract::The repeated measurements of heart rate variability (HRV) is more relevant than a single HRV measurement in predicting patient prognosis but is less addressed previously. This prospective study aimed to investigate the association between repeated measurements of HRV and long-term mortality in chronic hemodialysis pat...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Chang YM,Huang YT,Chen IL,Yang CL,Leu SC,Su HL,Kao JL,Tsai SC,Jhen RN,Shiao CC

    更新日期:2020-01-21 00:00:00

  • Effects of Nonsteroidal Anti-Inflammatory Drugs as Patient Controlled Analgesia on Early Bowel Function Recovery after Radical Cystectomy.

    abstract::This study aimed to evaluate the effects of ketorolac, a commonly used non-steroidal anti-inflammatory drug (NSAID) as patient controlled intravenous infusion analgesia (PCIA) for the patients underwent radical cystectomy (RC) due to bladder cancer regarding post-operational indices of recovery. Total seventy patients...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章


    authors: Yu YD,Hwang JH,Seo YE,Song BD,Jung YS,Lee DH,Hong SK,Byun SS,Lee SE,Oh JJ

    更新日期:2018-03-15 00:00:00

  • Shape-modification of patterned nanoparticles by an ion beam treatment.

    abstract::This paper evaluated a practical approach to the fabrication of arrays of non-spherical nanoparticles by colloidal etching without a mask involving exposure to a low energy ion beam. A spherical nanoparticle array was transferred using a soft nanolithography technique, which is a simple and effective pattern transfer ...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Heo KC,Gwag JS

    更新日期:2015-02-17 00:00:00

  • Author Correction: Novel Indole-fused benzo-oxazepines (IFBOs) inhibit invasion of hepatocellular carcinoma by targeting IL-6 mediated JAK2/STAT3 oncogenic signals.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误


    authors: Singh AK,Bhadauria AS,Kumar U,Raj V,Rai A,Kumar P,Keshari AK,Kumar D,Maity B,Nath S,Prakash A,Saha S

    更新日期:2020-02-06 00:00:00

  • Accurate dating of stalagmites from low seasonal contrast tropical Pacific climate using Sr 2D maps, fabrics and annual hydrological cycles.

    abstract::Tropical Pacific stalagmites are commonly affected by dating uncertainties because of their low U concentration and/or elevated initial 230Th content. This poses problems in establishing reliable trends and periodicities for droughts and pluvial episodes in a region vulnerable to climate change. Here we constrain the ...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Faraji M,Borsato A,Frisia S,Hellstrom JC,Lorrey A,Hartland A,Greig A,Mattey DP

    更新日期:2021-01-26 00:00:00

  • The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance.

    abstract::Cellular clearance mechanisms including the autophagy-lysosome pathway are impaired in amyotrophic lateral sclerosis (ALS). One of the most important proteins involved in the regulation of autophagy is the lysosomal Ca2+ channel Mucolipin TRP channel 1 (TRPML1). Therefore, we investigated the role of TRPML1 in a neuro...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Tedeschi V,Petrozziello T,Sisalli MJ,Boscia F,Canzoniero LMT,Secondo A

    更新日期:2019-07-24 00:00:00

  • Environmental filtering triggers community assembly of forest understorey plants in Central European pine stands.

    abstract::Habitat filtering models predict ecologically similar plant species to jointly colonize sites due to comparable environmental characteristics leading to an aggregated pattern of species spatial occurrence. Models focused on interspecific competition expect species with similar ecological requirements to be spatially s...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Ulrich W,Sewerniak P,Puchałka R,Piwczyński M

    更新日期:2017-03-21 00:00:00

  • Integrin α11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation.

    abstract::Integrin α11β1 is a collagen-binding integrin, which is receiving increasing attention in the context of wound healing and fibrosis. Although α11β1 integrin displays similar collagen specificity to α2β1 integrin, both integrins have distinct in vivo functions. In this context, the contribution of α11 subunit cytoplasm...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Erusappan P,Alam J,Lu N,Zeltz C,Gullberg D

    更新日期:2019-10-25 00:00:00

  • OCT-based label-free in vivo lymphangiography within human skin and areola.

    abstract::Due to the limitations of current imaging techniques, visualization of lymphatic capillaries within tissue in vivo has been challenging. Here, we present a label-free high resolution optical coherence tomography (OCT) based lymphangiography (OLAG) within human skin in vivo. OLAG enables rapid (~seconds) mapping of lym...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Baran U,Qin W,Qi X,Kalkan G,Wang RK

    更新日期:2016-02-19 00:00:00

  • Characterization and expression of the cytochrome P450 gene family in diamondback moth, Plutella xylostella (L.).

    abstract::Cytochrome P450 monooxygenases are present in almost all organisms and can play vital roles in hormone regulation, metabolism of xenobiotics and in biosynthesis or inactivation of endogenous compounds. In the present study, a genome-wide approach was used to identify and analyze the P450 gene family of diamondback mot...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Yu L,Tang W,He W,Ma X,Vasseur L,Baxter SW,Yang G,Huang S,Song F,You M

    更新日期:2015-03-10 00:00:00

  • Elemental and Molecular Segregation in Oil Paintings due to Lead Soap Degradation.

    abstract::The formation of Pb, Zn, and Cu carboxylates (soaps) has caused visible deterioration in hundreds of oil paintings dating from the 15th century to the present. Through transport phenomena not yet understood, free fatty acids in the oil binding medium migrate through the paint and react with pigments containing heavy m...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Chen-Wiegart YK,Catalano J,Williams GJ,Murphy A,Yao Y,Zumbulyadis N,Centeno SA,Dybowski C,Thieme J

    更新日期:2017-09-14 00:00:00

  • Transcriptomic analysis identifies novel genes and pathways for salt stress responses in Suaeda salsa leaves.

    abstract::Salinity is a critical abiotic stress, which significantly impacts the agricultural yield worldwide. Identification of the molecular mechanisms underlying the salt tolerance in euhalophyte Suaeda salsa is conducive to the development of salt-resistant crops. In the present study, high-throughput RNA sequencing was per...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Zhang X,Yao Y,Li X,Zhang L,Fan S

    更新日期:2020-03-06 00:00:00

  • Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk.

    abstract::The cannabinoid type 1 (CB1) receptor and the capsaicin receptor (TRPV1) exhibit co-expression and complex, but largely unknown, functional interactions in a sub-population of primary sensory neurons (PSN). We report that PSN co-expressing CB1 receptor and TRPV1 form two distinct sub-populations based on their pharmac...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Chen J,Varga A,Selvarajah S,Jenes A,Dienes B,Sousa-Valente J,Kulik A,Veress G,Brain SD,Baker D,Urban L,Mackie K,Nagy I

    更新日期:2016-09-22 00:00:00

  • Intravitreal aflibercept for active polypoidal choroidal vasculopathy without active polyps.

    abstract::The purpose of this study was to evaluate the efficacy of intravitreal aflibercept for active polypoidal choroidal vasculopathy (PCV) without active polyps and to identify prognostic factors. We enrolled 40 eyes from 40 patients who manifested PCV with exudation but without active polyps after prior treatment with pho...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Lee SE,Jang JW,Kang SW,Park KH,Lee DW,Kim JH,Bae K

    更新日期:2019-02-06 00:00:00

  • Effect of Crystal Orientation on Femtosecond Laser-Induced Thermomechanical Responses and Spallation Behaviors of Copper Films.

    abstract::Ultrafast thermomechanical responses and spallation behaviours of monocrystal copper films irradiated by femtosecond laser pulse are investigated using molecular dynamics simulation (MDS). Films with 〈100〉, 〈110〉 and 〈111〉 crystal orientations along the thickness direction were studied. The results show that the cryst...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Xiong QL,Li Z,Kitamura T

    更新日期:2017-08-23 00:00:00

  • Microglia retard dengue virus-induced acute viral encephalitis.

    abstract::Patients with dengue virus (DENV) infection may also present acute viral encephalitis through an unknown mechanism. Here, we report that encephalitic DENV-infected mice exhibited progressive hunchback posture, limbic seizures, limbic weakness, paralysis, and lethality 7 days post-infection. These symptoms were accompa...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Tsai TT,Chen CL,Lin YS,Chang CP,Tsai CC,Cheng YL,Huang CC,Ho CJ,Lee YC,Lin LT,Jhan MK,Lin CF

    更新日期:2016-06-09 00:00:00

  • The molecular genealogy of sequential overlapping inversions implies both homologous chromosomes of a heterokaryotype in an inversion origin.

    abstract::Cytological and molecular studies have revealed that inversion chromosomal polymorphism is widespread across taxa and that inversions are among the most common structural changes fixed between species. Two major mechanisms have been proposed for the origin of inversions considering that breaks occur at either repetiti...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Orengo DJ,Puerma E,Cereijo U,Aguadé M

    更新日期:2019-11-18 00:00:00

  • Enhanced Capacitance of Hybrid Layered Graphene/Nickel Nanocomposite for Supercapacitors.

    abstract::In this work, Ni nanoparticles were directly decorated on graphene (G) nanosheets via mechanical ball milling. Based on transmission electron microscopy observations, the Ni nanoparticles were well dispersed and attached to the G nanosheet without any agglomerations. Electrochemical results showed that the capacitance...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Mohd Zaid NA,Idris NH

    更新日期:2016-08-24 00:00:00

  • ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth.

    abstract::Cry1A insecticidal toxins bind sequentially to different larval gut proteins facilitating oligomerization, membrane insertion and pore formation. Cry1Ac interaction with cadherin triggers oligomerization. However, a mutation in an ABC transporter gene (ABCC2) is linked to Cry1Ac resistance in Plutella xylostella. Cry1...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Ocelotl J,Sánchez J,Gómez I,Tabashnik BE,Bravo A,Soberón M

    更新日期:2017-05-24 00:00:00

  • Fluorescence Polarization Switching from a Single Silicon Vacancy Colour Centre in Diamond.

    abstract::Single-photon emitters with stable and uniform photoluminescence properties are important for quantum technology. However, in many cases, colour centres in diamond exhibit spectral diffusion and photoluminescence intensity fluctuation. It is therefore essential to investigate the dynamics of colour centres at the sing...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Liu Y,Chen G,Rong Y,McGuinness LP,Jelezko F,Tamura S,Tanii T,Teraji T,Onoda S,Ohshima T,Isoya J,Shinada T,Wu E,Zeng H

    更新日期:2015-07-23 00:00:00

  • Parenteral administration of factor Xa/IIa inhibitors limits experimental aortic aneurysm and atherosclerosis.

    abstract::Intraluminal thrombus is a consistent feature of human abdominal aortic aneurysm (AAA). Coagulation factor Xa (FXa) catalyses FII to thrombin (FIIa). We examined the effect of FXa/FIIa inhibition on experimental aortic aneurysm in apolipoprotein E-deficient (ApoE-/-) mice infused with angiotensin II (AngII). The conce...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Moran CS,Seto SW,Krishna SM,Sharma S,Jose RJ,Biros E,Wang Y,Morton SK,Golledge J

    更新日期:2017-02-21 00:00:00

  • Differential diagnosis of vergence and saccade disorders in dyslexia.

    abstract::Previous studies suggest vergence and saccade abnormalities in dyslexic adolescents. However, these studies are mainly clinically based and do not provide objective measurements of eye movements, but rather subjectively evaluate vergence using haplosopic conditions in which the two eyes are dissociated (via polarizers...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Ward LM,Kapoula Z

    更新日期:2020-12-17 00:00:00

  • Central s-resistin deficiency ameliorates hypothalamic inflammation and increases whole body insulin sensitivity.

    abstract::S-resistin, a non-secretable resistin isoform, acts as an intracrine factor that regulates adipocyte maduration, inflammatory and insulin response in 3T3-L1 cells. However, its intracellular function in vivo is still unknown. In this study, we analyze the central role of s-resistin, decreasing its hypothalamic express...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Rodríguez M,Pintado C,Moltó E,Gallardo N,Fernández-Martos CM,López V,Andrés A,Arribas C

    更新日期:2018-03-02 00:00:00

  • Enhanced delignification of steam-pretreated poplar by a bacterial laccase.

    abstract::The recalcitrance of woody biomass, particularly its lignin component, hinders its sustainable transformation to fuels and biomaterials. Although the recent discovery of several bacterial ligninases promises the development of novel biocatalysts, these enzymes have largely been characterized using model substrates: di...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Singh R,Hu J,Regner MR,Round JW,Ralph J,Saddler JN,Eltis LD

    更新日期:2017-02-07 00:00:00

  • Association between preterm brain injury and exposure to chorioamnionitis during fetal life.

    abstract::Preterm infants are susceptible to inflammation-induced white matter injury but the exposures that lead to this are uncertain. Histologic chorioamnionitis (HCA) reflects intrauterine inflammation, can trigger a fetal inflammatory response, and is closely associated with premature birth. In a cohort of 90 preterm infan...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Anblagan D,Pataky R,Evans MJ,Telford EJ,Serag A,Sparrow S,Piyasena C,Semple SI,Wilkinson AG,Bastin ME,Boardman JP

    更新日期:2016-12-01 00:00:00