Abstract:
:Light and electron microscope comparisons were made of parotid and submandibular glands from male Swiss-Webster white mice 3, 13, and 18 months old. The glands from the 13- and 18-month-old mice were less organized and the parenchyma was not as dense. Fibrous connective tissue, intracellular lipofuscin granules, and residual body formation increased with age. In the cells of the parotid glands of 18-month-old mice, the nucleus-to-cytoplasm ratio was greater than in the specimens from the younger two ages. The granular convoluted tubules in submandibular glands of 18-month-old mice were the smallest of all age groups. The age changes appear comparable to those of rat and human salivary glands, yet this is an inexpensive animal model that achieves old age in less time than other animal models.
journal_name
Exp Gerontoljournal_title
Experimental gerontologyauthors
Meisel DL,Skobe Z,Prostak KS,Shklar Gdoi
10.1016/0531-5565(88)90007-1subject
Has Abstractpub_date
1988-01-01 00:00:00pages
197-210issue
3eissn
0531-5565issn
1873-6815journal_volume
23pub_type
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journal_title:Experimental gerontology
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2009.08.004
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/0531-5565(92)90055-5
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2009.05.004
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2014.01.022
更新日期:2014-04-01 00:00:00
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journal_title:Experimental gerontology
pub_type: 杂志文章
doi:10.1016/j.exger.2008.02.005
更新日期:2008-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Experimental gerontology
pub_type: 杂志文章,评审
doi:10.1016/j.exger.2010.09.008
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