Stillbirth and subsequent pregnancy outcome - a cohort from a large tertiary referral hospital.

Abstract:

:Objectives This study aimed to assess pregnancy and delivery outcomes in women with a history of stillbirth in a large tertiary referral hospital. Methods This was a retrospective study from Helsinki University Hospital, Finland. The cohort comprised 214 antepartum singleton stillbirths in the period 2003-2015 (case group). Of these, 154 delivered by the end of 2017. Adverse pregnancy outcomes were compared to those in singleton pregnancies of parous women in Finland from the Finnish Medical Birth Register (reference group). Results The rates of adverse pregnancy outcomes were higher among case women for preeclampsia (3.3 vs. 0.9%, P = 0.002), preterm birth (8.5 vs. 3.9%, P = 0.004), small-for-gestational-age (SGA) children (7.8 vs. 2.2%, P < 0.001) and stillbirth (2.7 vs. 0.3%, P < 0.001). There were four preterm recurrent stillbirths. Induction of labor was more common among case women than parous women in the reference group (49.4 vs. 18.3%, P < 0.001). Duration of pregnancy was shorter among case women (38.29 ± 3.20 vs. 39.27 ± 2.52, P < 0.001), and mean birth weight was lower among newborns of the case women (3274 ± 770 vs. 3491 ± 674 g, P < 0.001). Conclusion Although the rates for adverse pregnancy outcomes were higher compared to the parous background population, the overall probability of a favorable outcome was high. The risk of recurrent premature stillbirth in our cohort was higher than that for parous women in general during the study period. No recurrent term stillbirths occurred, however.

journal_name

J Perinat Med

authors

Pekkola M,Tikkanen M,Gissler M,Paavonen J,Stefanovic V

doi

10.1515/jpm-2019-0425

subject

Has Abstract

pub_date

2020-10-25 00:00:00

pages

765-770

issue

8

eissn

0300-5577

issn

1619-3997

pii

/j/jpme.ahead-of-print/jpm-2019-0425/jpm-2019-0425

journal_volume

48

pub_type

杂志文章,评审
  • Limit of viability in Japan: ethical consideration.

    abstract::Viability means "the quality or state of being able to live, grow and develop." Limit of viability has been changed along with the advancement of perinatal and neonatal medicine. The viability limit defined in the Japanese Motherhood Protection Act was amended from 24 to 22 completed weeks of gestation in 1991 based o...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2009.112

    authors: Nishida H,Sakuma I

    更新日期:2009-01-01 00:00:00

  • Betamimetics in fetal distress: randomised controlled trial.

    abstract::The objective of the study was to investigate if a single dose of Hexoprenaline administered to patients diagnosed as having fetal distress improves neonatal outcome and whether there are any side effects and complications related to hexoprenaline injection. Patients with fetal distress diagnosed by electronic fetal h...

    journal_title:Journal of perinatal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1515/jpme.1997.25.1.97

    authors: Kulier R,Gülmezoĝlu AM,Hofmeyr GJ,Van Gelderen CJ

    更新日期:1997-01-01 00:00:00

  • Doppler sonographic findings for hypertension in pregnancy and HELLP syndrome.

    abstract::Doppler examinations of the umbilical artery, both uterine arteries, and the fetal middle cerebral artery were performed in the third trimester in 18 patients with pregnancy induced hypertension, 52 patients with preeclampsia, and 32 patients with HELLP syndrome and the results were correlated with the parameters feta...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.1999.053

    authors: Joern H,Funk A,Rath W

    更新日期:1999-01-01 00:00:00

  • Association of chronic hepatitis B virus infection with preterm birth: our experience and meta-analysis.

    abstract:OBJECTIVES:To assess the association of chronic hepatitis B virus (HBV) infection with preterm birth (PTB). METHODS:A cohort of 20,498 pregnant women (497 HBV carriers with 20,001 non-HBV controls) with normal alanine aminotransferase (ALT) levels was selected from the Obstetrics & Gynecology Hospital of Nantong Unive...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,meta分析

    doi:10.1515/jpm-2016-0201

    authors: Cui AM,Shao JG,Li HB,Shen Y,Chen ZX,Zhang S,Bian ZL,Qin G,Cheng XY

    更新日期:2017-11-27 00:00:00

  • 4D assessment of fetal brain function in diabetic patients.

    abstract:OBJECTIVE:To assess whether there is a difference in the behavior of fetuses of pregnant women with diabetes under treatment with insulin, compared to fetuses of pregnant women without diabetes. MATERIALS AND METHODS:Kurjak's antenatal neurodevelopmental test (KANET) - a method that, by application of four-dimensional...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2016-0394

    authors: Antsaklis P,Porovic S,Daskalakis G,Kurjak A

    更新日期:2017-08-28 00:00:00

  • Prenatal diagnosis of fetal urogenital abnormalities with oligohydramnios by magnetic resonance imaging using turbo spin echo technique.

    abstract::Turbo spin echo technique is a sequence that enables T2 weighted magnetic resonance (MR) images to be obtained in a few seconds. The purpose of this study is to evaluate the usefulness of this sequence in the prenatal diagnosis of fetal urogenital abnormalities associated with oligohydramnios, which make the ultrasoun...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:

    authors: Takeuchi K,Moriyama T,Funakoshi T,Maruo T

    更新日期:1998-01-01 00:00:00

  • Erythrocyte deformability of nonpregnant, pregnant, and fetal blood.

    abstract::Erythrocyte deformability is an important determinant of microcirculation, of oxygen transport and release to the tissue. In an attempt to clarify the rheological peculiarity during pregnancy, erythrocyte deformability was measured in 10 nonpregnant controls and 10 pairs of mothers and newborns. When the hematocrit of...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1995.23.4.301

    authors: Eguchi K,Sawai T,Mizutani Y

    更新日期:1995-01-01 00:00:00

  • Duration, amplitude and shape of accelerations in relation to fetal body movements in behavioral state 2F.

    abstract::The relationship between fetal movements and fetal heart rate accelerations was analyzed in 34 healthy near term fetuses. Periods of coincidence 2F (C2F) with a mean duration of 34 +/- 6 minutes per fetus were selected, with a total of 463 accelerations. Nineteen percent of single body movements and 71% of compilation...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1991.19.1-2.73

    authors: van Woerden EE,van Geijn HP,Mantel R,Swartjes JM

    更新日期:1991-01-01 00:00:00

  • Uterine hemodynamics and fetal response to vena caval occlusion in sheep.

    abstract::The present experiments should show if vena caval occlusion (V. C. O.) results in a decrease in uterine blood flow and increase in uterine vascular resistance (UVR). We are further interested to know, if V. C. O. influences fetal heart rate (FHR) and fetal blood pressure (BP). ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1975.3.4.260

    authors: Künzel W,Kastendieck E,Böhme U,Feige A

    更新日期:1975-01-01 00:00:00

  • To 'C' or not to 'C'? Caesarean delivery upon maternal request: a review of facts, figures and guidelines.

    abstract::The last few decades have seen an unrelenting rise in caesarean section (CS) rates. In addition to an increase in numbers of CS performed worldwide, there has also been a change in the indications for CS, a reflection of changing times. A new dilemma facing obstetricians is the increasing demand for CS in the absence ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/jpm-2012-0049

    authors: D'Souza R,Arulkumaran S

    更新日期:2013-01-01 00:00:00

  • Optimized amniotic fluid analysis in patients suspected of intrauterine infection/inflammation.

    abstract:OBJECTIVE:To determine the combination of amniotic fluid (AF) tests with the best diagnostic accuracy for predicting intrauterine infection/inflammation (IUI) in patients with clinical suspicion of chorioamnionitis. STUDY DESIGN:This is a retrospective study of 34 pregnant women who presented with uterine tenderness, ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2011.110

    authors: Ford C,Genç MR

    更新日期:2011-09-21 00:00:00

  • The relationship between placental histology and cervical length in twin gestations.

    abstract:OBJECTIVE:To evaluate differences in placental lesions in twin pregnancies with and without mid-trimester sonographic cervical shortening. METHODS:Two groups of women were identified: those with twin gestations and a cervical length

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm.2010.077

    authors: Peláez LM,Chasen ST,Baergen RN

    更新日期:2010-09-01 00:00:00

  • Changes in cervical resistance and collagen fluorescence during gestation in rats.

    abstract::During pregnancy the role of the cervix shifts between two opposing functions. Throughout most of gestation, the cervix is rigid and resists tension in order to maintain the products of conception inside the uterus. At term, however, cervical function changes drastically in order to accommodate stretch and delivery. T...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.1999.026

    authors: Shi L,Shi SQ,Saade GR,Chwalisz K,Garfield RE

    更新日期:1999-01-01 00:00:00

  • Ultrasound study of fetal movements in singleton and twin pregnancies at 12-19 weeks.

    abstract::Objective To evaluate fetal behavioral differences between singleton and twin fetuses before 20 weeks of gestation using four-dimensional (4D) ultrasound. Methods 4D ultrasound was used to examine fetal movements in 58 singleton and 48 twin normal fetuses at 12-19 weeks. The frequencies of eight fetal movements were a...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2017-0158

    authors: AboEllail MAM,Kanenishi K,Mori N,Noguchi J,Marumo G,Hata T

    更新日期:2018-10-25 00:00:00

  • Stillbirths in women with pre-gravid obesity.

    abstract::Objective To determine the association between pre-gravid obesity and stillbirth. Methods A retrospective study of a population-based dataset of births at ≥34 weeks' gestation. We excluded fetal deaths due to lethal anomalies and intrapartum fetal deaths. We calculated the incidence of stillbirths, neonatal respirator...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2018-0266

    authors: Merc MD,Lučovnik M,Bregar AT,Verdenik I,Tul N,Blickstein I

    更新日期:2019-04-24 00:00:00

  • Fetal and uteroplacental flow velocity waveforms in abruptio placentae: report of two cases.

    abstract::This paper reports two cases of abruptio placentae assessed using pulsed Doppler at 29 and 30 weeks of gestation. Transvaginal pulsed Doppler showed abnormal uterine artery FVWs in both cases. One fetus with normal umbilical and normal middle cerebral artery FVWs was not acidotic and only midly hypoxic, whereas the ot...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1994.22.5.441

    authors: Sekizuka N,Hanaoka J,Takeuchi Y,Tokunaga A

    更新日期:1994-01-01 00:00:00

  • Investigating the preventive effect of vitamins C and E on preeclampsia in nulliparous pregnant women.

    abstract::Objectives Preeclampsia is a hypertensive disorder associated with pregnancy and is the leading cause of both maternal and neonatal morbidity and mortality. Recent reports suggest that free radical-induced endothelial cell injury might be an etiologic factor in the pathogenesis of preeclampsia. The aim of this study w...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2019-0469

    authors: Lorzadeh N,Kazemirad Y,Kazemirad N

    更新日期:2020-07-28 00:00:00

  • The origin of amniotic fluid monocytes/macrophages in women with intra-amniotic inflammation or infection.

    abstract::Background Monocytes, after neutrophils, are the most abundant white blood cells found in the amniotic cavity of women with intra-amniotic inflammation/infection. However, the origin of such cells has not been fully investigated. Herein, we determined (1) the origin of amniotic fluid monocytes/macrophages from women w...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2019-0262

    authors: Gomez-Lopez N,Romero R,Leng Y,Xu Y,Slutsky R,Levenson D,Pacora P,Jung E,Panaitescu B,Hsu CD

    更新日期:2019-10-25 00:00:00

  • Cerebral palsy and fetal inflammatory response syndrome: a review.

    abstract::Cerebral palsy (CP) is the most common cause of severe physical disability in childhood. The precise etiological factor for the development of the majority of cases of CP has not been identified, however, prematurity is considered to be the leading identifiable risk factor. During the last decade, intrauterine infecti...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2006.001

    authors: Bashiri A,Burstein E,Mazor M

    更新日期:2006-01-01 00:00:00

  • Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA).

    abstract::Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LC-PUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues during the second half of pregnancy, and several studies have provide...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2007.030

    authors: Koletzko B,Larqué E,Demmelmair H

    更新日期:2007-01-01 00:00:00

  • Thrombocytopoiesis in healthy term newborns.

    abstract:AIMS:Thrombocytopoiesis was investigated in term newborns determining thrombopoietin (TPO), reticulated platelets (PLRET) and blood platelets (PLT) in relation to gender. PATIENTS AND METHODS:The study was undertaken on 72 healthy term newborns, 33 girls and 39 boys. They fitted all criteria for healthy term newborns....

    journal_title:Journal of perinatal medicine

    pub_type: 临床试验,杂志文章

    doi:10.1515/JPM.2005.046

    authors: Wasiluk A

    更新日期:2005-01-01 00:00:00

  • The clinical value of KANET in studying fetal neurobehavior in normal and at-risk pregnancies.

    abstract:OBJECTIVES:The aim of this study was to evaluate the clinical value of Kurjak’s Antenatal Neurodevelopmental Test (KANET), a new test for fetal neurodevelopment. METHODS:One hundred seventeen prenatal neurological tests were performed by the KANET scoring system between 28 and 38 weeks of gestation in 24 low-risk (24 ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2011-0251

    authors: Honemeyer U,Talic A,Therwat A,Paulose L,Patidar R

    更新日期:2013-03-01 00:00:00

  • Maternal and perinatal outcomes in pregnancies with multiple sclerosis: a case-control study.

    abstract:OBJECTIVE:To assess whether maternal multiple sclerosis (MS) is associated with adverse pregnancy outcomes by determining the clinical course of disease during pregnancy and postpartum throughout a 10-year-period in a single tertiary center. METHODS:We conducted a case-control study that included pregnancies with a de...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2016-0060

    authors: Yalcin SE,Yalcin Y,Yavuz A,Akkurt MO,Sezik M

    更新日期:2017-05-24 00:00:00

  • Listeriosis in human pregnancy: a systematic review.

    abstract::Listeria is commonly found in processed and prepared foods and listeriosis is associated with high morbidity and mortality. Preventative measures are well prescribed and monitoring and voluntary recall of contaminated products has resulted in a 44% reduction in the prevalence of perinatal listeriosis in the USA. Pregn...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/jpm.2011.035

    authors: Lamont RF,Sobel J,Mazaki-Tovi S,Kusanovic JP,Vaisbuch E,Kim SK,Uldbjerg N,Romero R

    更新日期:2011-05-01 00:00:00

  • Effects of coronavirus 19 pandemic on maternal anxiety during pregnancy: a prospectic observational study.

    abstract::Objectives Coronavirus (COVID-19) is a new respiratory disease that is spreading widely throughout the world. The aim of this study was to evaluate the psychological impact of COVID-19 pandemic on pregnant women in Italy. Methods We considered 200 pregnancies attending our antenatal clinic. A questionnaire was sent to...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2020-0182

    authors: Mappa I,Distefano FA,Rizzo G

    更新日期:2020-07-28 00:00:00

  • A high concentration of fetal fibronectin in cervical secretions increases the risk of intra-amniotic infection and inflammation in patients with preterm labor and intact membranes.

    abstract::Objective To determine whether the risk of intra-amniotic infection/inflammation and spontaneous preterm delivery (SPTD) varies as a function of the concentration of cervical fetal fibronectin (fFN) in patients with preterm labor and intact membranes. Methods This prospective study included 180 patients with preterm l...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2018-0351

    authors: Oh KJ,Romero R,Park JY,Kang J,Hong JS,Yoon BH

    更新日期:2019-04-24 00:00:00

  • Post-delivery oxidative stress in women with preeclampsia or IUGR.

    abstract:AIM:To compare oxidative stress in patients with preeclampsia (PE) or intrauterine growth restriction (IUGR) vs. normal pregnancy (controls) during 48 h after delivery. STUDY DESIGN:Women with singleton pregnancies were recruited immediately after delivery (gestational age >26.0 weeks). Women with PE or IUGR were matc...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2008.053

    authors: Kressig P,Beinder E,Schweer H,Zimmermann R,von Mandach U

    更新日期:2008-01-01 00:00:00

  • Water birth--is it safe?

    abstract::Water births have gradually become more popular in industrialized countries during the last decade. People advocating this form of delivery argue that the buoyancy in water helps the mother to relax and that the warmth helps reduce pain, meaning that the whole labor process and experience is positively influenced and ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Zimmermann R,Huch A,Huch R

    更新日期:1993-01-01 00:00:00

  • The management of labor in women with more than one uterine scar: is a repeat cesarean section really the only "safe" option?

    abstract::A prospective trial to investigate feasibility of vaginal delivery after more than one cesarean section, and the safety of vaginal delivery for mother and neonate. Twenty-six pregnant women with a history of two or more cesarean sections were admitted to the delivery room and accepted trial of labor under internal fet...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1994.22.1.13

    authors: Granovsky-Grisaru S,Shaya M,Diamant YZ

    更新日期:1994-01-01 00:00:00

  • Longitudinal observation of deterioration of Doppler parameters, computerized cardiotocogram and clinical course in a fetus with growth restriction.

    abstract::We report on a fetus with intrauterine growth restriction detected at 27 weeks' gestation, who was longitudinally followed up until delivery by cesarean section 33 days later (31 + 5 weeks) due to severe decelerations in CTG. Longitudinal Doppler assessment of the umbilical artery (UA), the middle cerebral artery (MCA...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2001.010

    authors: Machlitt A,Wauer RR,Chaoui R

    更新日期:2001-01-01 00:00:00