Abstract:
:Doppler examinations of the umbilical artery, both uterine arteries, and the fetal middle cerebral artery were performed in the third trimester in 18 patients with pregnancy induced hypertension, 52 patients with preeclampsia, and 32 patients with HELLP syndrome and the results were correlated with the parameters fetal outcome. For 74% of the patients this was the first pregnancy, in 93% of the cases a cesarean section was necessary; 66% of the newborn babies were dystrophic and 90% of them were born prematurely. The blood flow in one uterine artery was restricted in 95% of all 102 pregnant women, only 5% did not show any pathological findings. A pathological blood flow was observed on Doppler sonography in the umbilical artery in 70% of the group and 39% showed a pathologically increased perfusion of the fetal middle cerebral artery. The average birth weights and gestational ages in the study group were markedly reduced in comparison with healthy pregnant women (pregnancy induced hypertension: 1620 g/35 weeks; preeclampsia: 1660 g/34 weeks; HELLP syndrome: 1160 g/31 weeks, respectively). The lowest values for average birth weight and gestational age occurred when all four investigated blood vessels showed pathological Doppler findings: 1180 g/31 weeks (0 to 1 pathological vascular findings: 2780 g/38 weeks; 2 pathological vascular findings: 1845 g/34.5 weeks; 3 pathological vascular findings: 1330 g/31 weeks). This Doppler study underlines the importance of examining four blood vessels: the uterine, the umbilical, and the fetal middle cerebral arteries for a complete analysis of the fetoplacental hemodynamics. On account of the severely impaired hemodynamics observed in the placentas of our patients with hypertensive diseases in pregnancy or HELLP syndrome, we believe the early diagnosis of these disorders by Doppler sonography and an early start of therapy to be essential.
journal_name
J Perinat Medjournal_title
Journal of perinatal medicineauthors
Joern H,Funk A,Rath Wdoi
10.1515/JPM.1999.053keywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
388-94issue
5eissn
0300-5577issn
1619-3997journal_volume
27pub_type
杂志文章abstract::The energy and redox states of placentas in newly anesthetized or sacrificed guinea pigs and sheep were compared with that of human placentas immediately after delivery. Subsequently the effect of ischemia was observed in both human and animal placentas. The influence of perfusion, using a fluid containing oxygenated ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1987.15.1.21
更新日期:1987-01-01 00:00:00
abstract::Objectives MR compatible incubators (MRcI) offer the examination of preterm and critically ill infants in controlled environment. The aim of the study was to compare objective and subjective image quality as well as diagnostic value of MRI brain examinations with and without using the MRcI. Thus, predictive value of b...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2020-0051
更新日期:2020-09-25 00:00:00
abstract:OBJECTIVE:To evaluate whether uterotrophic agents increase the risk of fatal hemorrhagic brain stroke. METHODS:Between 1991 and 1992, there were 230 maternal deaths among 2,420,000 pregnant women in Japan and the causes of these deaths was investigated in 1994. Using information provided in this report, we identified ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2010.116
更新日期:2011-01-01 00:00:00
abstract:AIM:To evaluate the short-term effects of blood transfusion on iron status [hemoglobin, ferritin, soluble transferrin receptor (sTfR), and reticulocyte count], hepcidin, and erythropoietin in stable preterm infants. METHOD:Sixty-three preterm infants treated with red blood cell transfusions (RBCTs) were included. Veno...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2015-0361
更新日期:2016-10-01 00:00:00
abstract:AIM:To identify cardiotocography (CTG) patterns associated with increased risk of intrapartum fetal acidemia. METHODS:A prospective observational cohort study of 1070 women with fetal scalp blood sampling (FBS) during labor was conducted at Karolinska University Hospital, Stockholm, Sweden. Women with a nonreassuring ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0105
更新日期:2015-07-01 00:00:00
abstract::Status and school achievement of 129 children born in Hessen between 1988 and 1992 and notified by a repeatedly elevated concentration of TSH in neonatal screening were evaluated. Interviews of mothers, teachers and pediatricians were used to score the development and educational achievements, respectively. A total of...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2005.097
更新日期:2005-01-01 00:00:00
abstract::In present-day obstetrics, cesarean delivery occurs in one in three women in the United States, and in up to four of five women in some regions of the world. The history of cesarean section extends well over four centuries. Up until the end of the nineteenth century, the operation was avoided because of its high morta...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm-2020-0305
更新日期:2020-09-04 00:00:00
abstract::Neuraxial labor analgesia can be initiated via combined spinal-epidural (CSE) or stand-alone epidural. Pros and cons of these techniques are outlined in this review. In recent years computer-integrated patient-controlled epidural analgesia (CI-PCEA) and programed intermittent epidural boluses (PIEB) have been develope...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm-2016-0118
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to determine EKG and 2-D echocardiographic criteria of ventricular dominance in preterm infants and select those by which ventricular dominance could be established by EKG alone. METHODS:A database was constructed from EKG and 2-D echocardiographic measurements on preterm infants...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.1999.040
更新日期:1999-01-01 00:00:00
abstract::Rescue cervical cerclage (RCC), also known as emergency cerclage, has long been the subject of controversy. Its use in women who have a dilated cervix has been ambivalent. RCC is often considered as a salvage measure for pregnancies which are at a high risk of severe preterm delivery (PTD) or mid-trimester miscarriage...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2017-0311
更新日期:2018-10-25 00:00:00
abstract::Objectives Coronavirus (COVID-19) is a new respiratory disease that is spreading widely throughout the world. The aim of this study was to evaluate the psychological impact of COVID-19 pandemic on pregnant women in Italy. Methods We considered 200 pregnancies attending our antenatal clinic. A questionnaire was sent to...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2020-0182
更新日期:2020-07-28 00:00:00
abstract::A prospective study was conducted to determine the effects of maternal smoking and alcohol consumption during pregnancy on the birth weight of fetuses in an unselected study population. Several confounding factors were taken into account. The main factors associated with an increase of birth weight of both sexes were ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1988.16.3.249
更新日期:1988-01-01 00:00:00
abstract::Serum calcium and 25-OH-D3 in mothers of newborns with craniotabes. The aim of this study was to investigate whether calcium or vitamin D balance during late pregnancy have influence on the outcome of newborn craniotabes. 27 mothers and their fullterm newborns with craniotabes in two series were studied for clinical f...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1983.11.2.127
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVE:To analyze data from a registry of Japanese neonates with hypoxic respiratory failure associated with pulmonary hypertension (PH) to compare the effectiveness of inhaled nitric oxide (iNO) in neonates born <34 weeks vs. ≥34 weeks gestational age (GA). MATERIALS AND METHODS:iNO was administered according to a...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2017-0040
更新日期:2018-08-28 00:00:00
abstract::The somatic growth of a regional birth cohort of 351 preterm infants was followed during their first two years. The measurements of weight, height, head and thorax circumferences took place at the well-baby clinics run by public health nurses at 3, 6, 12, 18 and 24 months of conceptional age. The growth of the preterm...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1989.17.1.41
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To assess whether there is a difference in the behavior of fetuses of pregnant women with diabetes under treatment with insulin, compared to fetuses of pregnant women without diabetes. MATERIALS AND METHODS:Kurjak's antenatal neurodevelopmental test (KANET) - a method that, by application of four-dimensional...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2016-0394
更新日期:2017-08-28 00:00:00
abstract::In tocolysis with beta-sympathicomimetics Verapamil is administered universally to reduce the subjective and objective cardiovascular side effects. The efficacy of the calcium-antagonist has not yet been substantiated. This has now re-emerged as an important issue due to the increasing occurrance of cardiopulmonary co...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1981.9.5.235
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:To assess risk factors for adverse perinatal and neonatal outcomes in "well-selected" singleton vaginal breech deliveries at term. METHODS:During the time span from January 2008 up to April 2015 a total of 786 singleton term breech deliveries with a planned vaginal delivery were identified in a retrospective...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2015-0342
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To evaluate differences in placental lesions in twin pregnancies with and without mid-trimester sonographic cervical shortening.
METHODS:Two groups of women were identified: those with twin gestations and a cervical length journal_title:Journal of perinatal medicine pub_type: 杂志文章 doi:10.1515/jpm.2010.077 更新日期:2010-09-01 00:00:00
abstract::The excretion of ketobemidone into human breast milk was investigated in three women who obtained ketobemidone as postoperative pain relief after Cesarean section and two women premedicated with 5 mg of ketobemidone before currettage after delivery. The highest observed concentration of ketobemidone in breast milk was...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1996.24.3.293
更新日期:1996-01-01 00:00:00
abstract::Thirty-one pregnant women divided into three groups (AGA prepartum, SGA prepartum without distress, AGA in labor) were examined using Doppler ultrasonography before, during and after oxygen administration to mothers via a face mask. The aim of the study was to find out if there was any effect on the blood flow values ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1991.19.3.185
更新日期:1991-01-01 00:00:00
abstract::The purpose of this study was to determine the effects of maternal phencyclidine use on the fetus. Ninety-four neonates with maternal phencyclidine exposure were compared with 94 controls. Maternal phencyclidine use was assessed by questionnaire and repeated urine testing. Mothers of study and control patients were ma...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1987.15.2.185
更新日期:1987-01-01 00:00:00
abstract:AIM:Inhaled nitric oxide (iNO) is used to treat neonates with hypoxic respiratory failure (HRF). The aim of this study was to determine clinical characteristics and factors associated with non-response to iNO therapy that may assist in clinical management and weaning strategies. METHODS:Retrospective chart review. The...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2015-0210
更新日期:2016-08-01 00:00:00
abstract::The objective of this study was to analyse the relation between severity of maternal condition at the time of intensive care unit (ICU) admission and various individual and institutional factors. This study analysed data from a retrospective population-based study in three French regions during 1991. The population st...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1998.26.5.354
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To determine the effects of Betamethasone injections on maternal white blood cell counts. STUDY DESIGN:Thirteen pregnant women without fever or clinical infection and with premature rupture of the membranes at less than 34 weeks gestation were studied. No subject had labor during the week of study. Daily com...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1998.26.3.204
更新日期:1998-01-01 00:00:00
abstract:UNLABELLED:The aim of this study was to evaluate the fluctuation of fetal pH in blood samples taken at the beginning of labor and at the moment of birth as related to intrauterine growth retardation syndrome. This is a prospective follow-up of term gestations, of which 41 were diagnosed as intrauterine growth retardati...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1994.22.4.329
更新日期:1994-01-01 00:00:00
abstract::Current approaches to the detection of patients at risk for preterm delivery (PTD) have focused on the diagnosis of preterm labor. However, these approaches are complicated by treatment biases and our inability to convincingly differentiate preterm labor from Braxton-Hicks contractions. Moreover, preterm labor with in...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpme.1993.21.6.441
更新日期:1993-01-01 00:00:00
abstract:AIM:The present study attempts to understand the role of methylenetetrahydrofolate reductase C677T (MTHFR C677T) in recurrent pregnancy losses in North Indian women because of hyperhomocysteinemia in light of serum folate and vitamin B₁₂. METHODS:One hundred and seven women with three or more consecutive unexplained r...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2012-0252
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To estimate the influence of fetal growth restriction (FGR) on neonatal morbidity and mortality among premature discordant twin neonates. STUDY DESIGN:Our medical records (2002-2007) of preterm twins born at 24-37 weeks' gestation were reviewed. Significant discordance was defined as >15% difference in birth...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2011.013
更新日期:2011-05-01 00:00:00
abstract::Postpartum hemorrhage is a continuing problem occurring in 5-10% of all deliveries. Due to recent problems with blood transfusion, heterologous blood is nowadays restricted to life-threatening indications. As a consequence the clinician is faced with many patients suffering from overt symptoms of anemia. We therefore ...
journal_title:Journal of perinatal medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1515/jpme.1995.23.1-2.111
更新日期:1995-01-01 00:00:00