Excretion of ketobemidone in human breast milk.

Abstract:

:The excretion of ketobemidone into human breast milk was investigated in three women who obtained ketobemidone as postoperative pain relief after Cesarean section and two women premedicated with 5 mg of ketobemidone before currettage after delivery. The highest observed concentration of ketobemidone in breast milk was 36 ng/ml three hours after administration, and 4-7 hours after administration the concentration was 3-5 fold that in maternal plasma. It could be estimated that the newborn will be exposed to less than 2 micrograms of ketobemidone during the first 24 hours.

journal_name

J Perinat Med

authors

Gerdin E,Bondesson U,Hartvig P

doi

10.1515/jpme.1996.24.3.293

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

293-5

issue

3

eissn

0300-5577

issn

1619-3997

journal_volume

24

pub_type

杂志文章
  • Oxytocin utilization for labor induction in obese and lean women.

    abstract::To determine if oxytocin dosage used for labor induction differed in obese and lean women, we analyzed records of patients who underwent term labor induction and delivered vaginally. Each of a cohort of 27 patients with a body mass index (BMI) >40 kg/m2 was matched with a patient with a BMI <28 kg/m2 for gestational a...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2014-0134

    authors: Hill M,Reed KL,Cohen WR

    更新日期:2015-11-01 00:00:00

  • Does rescue cerclage work?

    abstract::Rescue cervical cerclage (RCC), also known as emergency cerclage, has long been the subject of controversy. Its use in women who have a dilated cervix has been ambivalent. RCC is often considered as a salvage measure for pregnancies which are at a high risk of severe preterm delivery (PTD) or mid-trimester miscarriage...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2017-0311

    authors: Shivani D,Quek BH,Tan PL,Shephali T

    更新日期:2018-10-25 00:00:00

  • The frequency and clinical significance of intra-amniotic infection and/or inflammation in women with placenta previa and vaginal bleeding: an unexpected observation.

    abstract:OBJECTIVE:Idiopathic vaginal bleeding, a common complication of pregnancy, increases the risk of small-for-gestational age (SGA) neonate, preeclampsia and preterm delivery and can be the only clinical manifestation of intra-amniotic infection and/or inflammation (IAI). Placenta previa is thought to be protective agains...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm.2010.001

    authors: Madan I,Romero R,Kusanovic JP,Mittal P,Chaiworapongsa T,Dong Z,Mazaki-Tovi S,Vaisbuch E,Alpay Savasan Z,Yeo L,Kim CJ,Hassan SS

    更新日期:2010-05-01 00:00:00

  • Myocardial infarction in early pregnancy.

    abstract::Acute myocardial infarction (AMI) during pregnancy is usually transmural and occurs in late pregnancy with a peak incidence during the peripartum or postpartum periods. We report a pregnancy-related AMI, which occurring as early as the first trimester, was treated conservatively with antithrombotic and anti-ischemic d...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2004.127

    authors: Stefanovic V,Ulander VM,Graner M,Kupari M,Kaaja R

    更新日期:2004-01-01 00:00:00

  • Clinical usefulness of pulse oximetry in the fetus with non-reassuring heart rate pattern?

    abstract:UNLABELLED:The objective of this study was the evaluation of intrapartum pulse oximetry as an indicator of fetal distress and the condition of the newborn during clinical routine surveillance in an University Perinatal Center. Between 1998 and 1999 pulse oximetry (SpO2) was used additionally to routine fetal monitoring...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2000.037

    authors: Schmidt S,Koslowski S,Sierra F,Meyer-Wittkopf M,Heller G

    更新日期:2000-01-01 00:00:00

  • Fetal heart rate acceleration in response to light stimulation as a clinical measure of fetal well-being. A preliminary report.

    abstract::Numerous tests have been proposed for the assessment of fetal condition during the antenatal period. This preliminary report suggests the possibility of exposing the fetus-in-utero to alternating light during amnioscopy, with simultaneous registration of the fetal heart rate. This simple, non-invasive, inexpensive tes...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1980.8.1.38

    authors: Peleg D,Goldman JA

    更新日期:1980-01-01 00:00:00

  • Defining hypoxic ischemic encephalopathy in newborn infants: benchmarking in a South African population.

    abstract:OBJECTIVES:There are few population-based studies of hypoxic ischemic encephalopathy (HIE) in sub-Saharan Africa, and the published criteria that are used to define and grade HIE are too variable for meaningful comparisons between studies and populations. Our objectives were (1) to investigate how the incidence of HIE ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1515/jpm-2012-0107

    authors: Horn AR,Swingler GH,Myer L,Harrison MC,Linley LL,Nelson C,Tooke L,Rhoda NR,Robertson NJ

    更新日期:2013-03-01 00:00:00

  • Rational use of Doppler ultrasound in perinatal medicine.

    abstract::Doppler ultrasound velocimetry of uteroplacental, umbilical and fetal vessels provides the clinician with important information on the hemodynamics of respective vascular area. Gestational age-related reference values have been established for maternal uterine and arcuate artery, umbilical artery, fetal descending aor...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Marsál K

    更新日期:1994-01-01 00:00:00

  • Placental pathology and pregnancy outcomes in donor and non-donor oocyte in vitro fertilization pregnancies.

    abstract:OBJECTIVE:Intrinsically poor maternal adaptation to pregnancy and dysregulated processes have been postulated to occur as a consequence of an immune response to the feto-placental unit as "foreign" material. The aim of our study was to compare placental pathology and pregnancy outcomes of in vitro fertilization (IVF) p...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2005.004

    authors: Perni SC,Predanic M,Cho JE,Baergen RN

    更新日期:2005-01-01 00:00:00

  • Justified skepticism about Apgar scoring in out-of-hospital birth settings.

    abstract:BACKGROUND:The Apgar score is used worldwide to assess the newborn infant shortly after birth. Apgar scores, including mean scores and those with high cut-off scores, have been used to support claims that planned home birth is as safe as hospital birth. The purpose of this study was to determine the distribution of 5 m...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2014-0003

    authors: Grünebaum A,McCullough LB,Brent RL,Arabin B,Levene MI,Chervenak FA

    更新日期:2015-07-01 00:00:00

  • Thermographic demonstration of nonshivering thermogenesis in human newborns after birth: its relation to umbilical gases.

    abstract::This study was undertaken to measure the extent of nonshivering thermogensis (NST) in brown adipose tissue of human newborns receiving routine thermal care and to examine the influence of oxygen levels at birth on the initiation of NST. Fifteen human neonates were studied in an incubator set at 31-31 degrees C. Thermo...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1997.25.5.447

    authors: Oya A,Asakura H,Koshino T,Araki T

    更新日期:1997-01-01 00:00:00

  • Iron homeostasis after blood transfusion in stable preterm infants - an observational study.

    abstract:AIM:To evaluate the short-term effects of blood transfusion on iron status [hemoglobin, ferritin, soluble transferrin receptor (sTfR), and reticulocyte count], hepcidin, and erythropoietin in stable preterm infants. METHOD:Sixty-three preterm infants treated with red blood cell transfusions (RBCTs) were included. Veno...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2015-0361

    authors: Herzlich J,Litmanovitz I,Regev R,Bauer S,Sirota G,Steiner Z,Arnon S

    更新日期:2016-10-01 00:00:00

  • Primary vs. secondary recurrent pregnancy loss--epidemiological characteristics, etiology, and next pregnancy outcome.

    abstract:OBJECTIVE:To compare epidemiological and obstetric characteristics, etiology and next pregnancy outcomes of women with primary vs. secondary recurrent pregnancy loss (RPL). STUDY DESIGN:A retrospective cohort study, including 420 patients with two or more consecutive pregnancy losses followed by a subsequent (index) p...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2011-0315

    authors: Shapira E,Ratzon R,Shoham-Vardi I,Serjienko R,Mazor M,Bashiri A

    更新日期:2012-02-29 00:00:00

  • Thrombophilia testing in pregnancy: should we agree to disagree?

    abstract::The value of testing for inherited thrombophilia in pregnancy has been debated in literature with regard to its utility in preventing adverse obstetrical outcomes or identifying women at risk for it. In this commentary, an evidence based approach is used to investigate the strength of association between thrombophilia...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2014-0075

    authors: Lopes L,Jacob GP

    更新日期:2015-03-01 00:00:00

  • Uterine hemodynamics and fetal response to vena caval occlusion in sheep.

    abstract::The present experiments should show if vena caval occlusion (V. C. O.) results in a decrease in uterine blood flow and increase in uterine vascular resistance (UVR). We are further interested to know, if V. C. O. influences fetal heart rate (FHR) and fetal blood pressure (BP). ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1975.3.4.260

    authors: Künzel W,Kastendieck E,Böhme U,Feige A

    更新日期:1975-01-01 00:00:00

  • Antenatal and postnatal treatment of pleural effusion and extra-lobar pulmonary sequestration.

    abstract::An infant is reported who was identified antenatally to have an extralobar sequestration and a pleural effusion. Chronic drainage of the effusion was achieved by placement of a pleuroamniotic shunt. After delivery the infant underwent several thoracocenteses and then definitive surgery to remove an extralobar sequestr...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1996.24.4.335

    authors: Chan V,Greenough A,Nicolaides KN

    更新日期:1996-01-01 00:00:00

  • The use of dextrostix and dextrostix reflectance meters in the diagnosis of neonatal hypoglycemia.

    abstract::Dextrostix is now widely used as a method of screening for hypoglycemia of the newborn. There has always been some anxiety about its accuracy for estimating very low blood sugars; this is important, since symptomatic hypoglycemia of the newborn does not usually occur until the blood glucose falls below 20 mg/dl. In 19...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1976.4.2.106

    authors: Harvey DR,Cooper LV,Fancourt RF,Levene M,Schoberg T

    更新日期:1976-01-01 00:00:00

  • Chronic hypertension in pregnancy: color Doppler investigation of uterine arteries as a predictive test for superimposed preeclampsia and adverse perinatal outcome.

    abstract::To determine if uterine artery Doppler velocimetry is useful in identifying chronic hypertensive pregnancies at risk for superimposed preeclampsia and adverse perinatal outcome. Resistance index (RI) was assessed by color velocimetry at the level of uterine arteries at 23-24 weeks of gestation in 42 women with chronic...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1996.24.2.141

    authors: Caruso A,Caforio L,Testa AC,Ferrazzani S,Mastromarino C,Mancuso S

    更新日期:1996-01-01 00:00:00

  • Listeriosis in human pregnancy: a systematic review.

    abstract::Listeria is commonly found in processed and prepared foods and listeriosis is associated with high morbidity and mortality. Preventative measures are well prescribed and monitoring and voluntary recall of contaminated products has resulted in a 44% reduction in the prevalence of perinatal listeriosis in the USA. Pregn...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/jpm.2011.035

    authors: Lamont RF,Sobel J,Mazaki-Tovi S,Kusanovic JP,Vaisbuch E,Kim SK,Uldbjerg N,Romero R

    更新日期:2011-05-01 00:00:00

  • Correlates of the trend of cesarean section rates in twin pregnancies.

    abstract:OBJECTIVE:To examine the population-based trend for cesarean births in twin pregnancies for the last 13 years in Slovenia, and to find correlates for this trend. METHODS:We evaluated data from the Slovenian national perinatal information system (NPIS) of all twin pairs born at ≥24 weeks during the period 1997-2009 (n=...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2011.129

    authors: Tul N,Verdenik I,Trojner-Bregar A,Novak Ž,Blickstein I

    更新日期:2012-04-01 00:00:00

  • A randomized trial of cerclage vs. 17 alpha-hydroxyprogesterone caproate for treatment of short cervix.

    abstract:OBJECTIVE:To determine pregnancy outcome in patients with short cervix on transvaginal ultrasound between 16 and 24 weeks' gestation treated with McDonald cerclage compared to weekly intramuscular injections of 17 alpha-hydroxyprogesterone caproate (17OHP-C). METHODS:From November 2003 through December 2006, asymptoma...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1515/JPM.2009.083

    authors: Keeler SM,Kiefer D,Rochon M,Quinones JN,Novetsky AP,Rust O

    更新日期:2009-01-01 00:00:00

  • Increased inorganic sulfate concentrations in amniotic fluid.

    abstract::We assayed inorganic sulfate by ion chromatography in 49 amniotic fluid samples from pregnancies of 14 to 38 weeks gestation. In second trimester samples (14 to 26 weeks gestation), amniotic fluid sulfate concentrations (317 +/- 22 mumol/L, mean +/- SE; n = 32) were not different from previously reported maternal seru...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1992.20.6.443

    authors: Cole DE,Oulton M,Stirk LJ,Magor B

    更新日期:1992-01-01 00:00:00

  • Fetal complications due to intrahepatic cholestasis of pregnancy.

    abstract::Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder of pregnancy. Diagnosis is based on the clinical picture, particularly the presence of pruritus with a deterioration of liver function tests, and typically elevated serum levels of total bile acids. ICP manifests in the second half of pregna...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/jpm-2014-0089

    authors: Šimják P,Pařízek A,Vítek L,Černý A,Adamcová K,Koucký M,Hill M,Dušková M,Stárka L

    更新日期:2015-03-01 00:00:00

  • Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA).

    abstract::Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LC-PUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues during the second half of pregnancy, and several studies have provide...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/JPM.2007.030

    authors: Koletzko B,Larqué E,Demmelmair H

    更新日期:2007-01-01 00:00:00

  • New approaches to the prediction of preterm delivery.

    abstract::Current approaches to the detection of patients at risk for preterm delivery (PTD) have focused on the diagnosis of preterm labor. However, these approaches are complicated by treatment biases and our inability to convincingly differentiate preterm labor from Braxton-Hicks contractions. Moreover, preterm labor with in...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,评审

    doi:10.1515/jpme.1993.21.6.441

    authors: Lockwood CJ,Dudenhausen JW

    更新日期:1993-01-01 00:00:00

  • Maternal serum lipid profile in pregnancies complicated by hypertensive disorders.

    abstract::Plasma lipoprotein, cholesterol and triglycerides were determined in 34 hypertensive pregnant patients and in 17 healthy full term pregnant women. Pregnancy induced hypertension was diagnosed in 21 patients and chronic hypertension in the remaining 13 women. Serum triglyceride levels were significantly elevated in the...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpme.1990.18.6.473

    authors: Kokia E,Barkai G,Reichman B,Segal P,Goldman B,Mashiach S

    更新日期:1990-01-01 00:00:00

  • Long-term epidural block treatment in patients with early threatening preterm delivery and vaginal fetal engagement.

    abstract::We report on an exceptional therapy with epidural anesthesia and tunnelling of the peridural catheter over a time period of 2-14 days in patients with threatening early preterm labor, intact membranes and vaginal engagement of the infants (4 singleton, 8 twin and 2 triplet pregnancies). A combination of bupivacaine (0...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/JPM.2008.081

    authors: Arabin B,Kuizenga K,van Zoeren D,Eyck JV

    更新日期:2008-01-01 00:00:00

  • Ultrasound study of fetal movements in singleton and twin pregnancies at 12-19 weeks.

    abstract::Objective To evaluate fetal behavioral differences between singleton and twin fetuses before 20 weeks of gestation using four-dimensional (4D) ultrasound. Methods 4D ultrasound was used to examine fetal movements in 58 singleton and 48 twin normal fetuses at 12-19 weeks. The frequencies of eight fetal movements were a...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm-2017-0158

    authors: AboEllail MAM,Kanenishi K,Mori N,Noguchi J,Marumo G,Hata T

    更新日期:2018-10-25 00:00:00

  • Do uterotrophic drugs increase the risk of fatal hemorrhagic brain stroke?

    abstract:OBJECTIVE:To evaluate whether uterotrophic agents increase the risk of fatal hemorrhagic brain stroke. METHODS:Between 1991 and 1992, there were 230 maternal deaths among 2,420,000 pregnant women in Japan and the causes of these deaths was investigated in 1994. Using information provided in this report, we identified ...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章

    doi:10.1515/jpm.2010.116

    authors: Yamada T,Yamada T,Morikawa M,Takeda M,Akaishi R,Nishida R,Araki N,Koyama T,Minakami H

    更新日期:2011-01-01 00:00:00

  • Labour epidural analgesia and anti-infectious management of the neonate: a meta-analysis.

    abstract:BACKGROUND:A known side effect of labour epidural analgesia (EDA) is maternal fever. It is unclear whether this has effects on the anti-infectious management of the neonate. METHODS:A systematic literature search and a hand search of abstract publications were conducted. Studies reporting sepsis evaluation or antibiot...

    journal_title:Journal of perinatal medicine

    pub_type: 杂志文章,meta分析

    doi:10.1515/jpm-2012-0064

    authors: Heesen M,Klöhr S,Rossaint R,Straube S,Van de Velde M

    更新日期:2012-11-01 00:00:00