4D assessment of fetal brain function in diabetic patients.

Abstract:

OBJECTIVE:To assess whether there is a difference in the behavior of fetuses of pregnant women with diabetes under treatment with insulin, compared to fetuses of pregnant women without diabetes. MATERIALS AND METHODS:Kurjak's antenatal neurodevelopmental test (KANET) - a method that, by application of four-dimensional (4D) ultrasound, assesses fetal behavior in a similar way that neonatologists perform a neurological assessment in newborns - was applied from 28 to 38 weeks of gestation to 40 pregnancies with pre-existing diabetes mellitus or gestational diabetes mellitus (GDM) requiring insulin (diabetic group) and to 40 non-diabetic cases, with otherwise low-risk pregnancies (non-diabetic group). RESULTS:There were no statistically significant differences regarding maternal age (30.5±5.1 years for diabetic group vs. 29.8±6.2 years for non-diabetic group) and gestational age (32±1.6 weeks for the diabetic group compared to 33±1.2 weeks for the non-diabetic group). After analysis of the results obtained from application of KANET to each group, results of KANET had higher scores in the non-diabetic group. CONCLUSION:It appears that there are differences in the fetal behavior between diabetic and non-diabetic fetuses, and also the specific parameters - movements that were different between the two groups were identified.

journal_name

J Perinat Med

authors

Antsaklis P,Porovic S,Daskalakis G,Kurjak A

doi

10.1515/jpm-2016-0394

subject

Has Abstract

pub_date

2017-08-28 00:00:00

pages

711-715

issue

6

eissn

0300-5577

issn

1619-3997

pii

/j/jpme.ahead-of-print/jpm-2016-0394/jpm-2016-0394

journal_volume

45

pub_type

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