The impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low-risk primigravid population.

Abstract:

AIMS:To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population. METHODS:Prospective recruitment of 1011 low-risk primigravidas with uterine and umbilical artery Doppler assessment at 22-24 weeks and 36 weeks. All mothers and infants were reviewed postnatally with a retrospective analysis of ultrasound and clinical outcome data. RESULTS:Elevated uterine artery indices were associated with increased rates of threatened miscarriage, higher rates of pre-eclampsia (PET) and a higher incidence of fetal birth weight <2nd and 9th centile for gestation. Uterine artery pulsatility index (PI) >95th centile for gestation was associated with statistically higher rates of small-for-gestational age (SGA) infants. Elevated umbilical artery indices were associated with higher rates of induction of labor and a higher incidence of fetal birth weight infants <2nd and 9th centile for gestation. Umbilical artery PI >95th centile for gestation was associated with statistically higher rates of SGA infants. CONCLUSION:Elevated uterine and umbilical artery indices are associated with higher rates of maternal and fetal disease.

journal_name

J Perinat Med

authors

Cooley SM,Donnelly JC,Walsh T,MacMahon C,Gillan J,Geary MP

doi

10.1515/jpm.2010.130

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

143-9

issue

2

eissn

0300-5577

issn

1619-3997

journal_volume

39

pub_type

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