Abstract:
OBJECTIVE:The aim of the present study was to assess, in a population of dichorionic twin pregnancies with selective growth restriction, the effect of inter-twin differences by use of Doppler velocimetry and fetal growth discordancy on perinatal outcomes. METHODS:This was a retrospective study including dichorionic twin pregnancies from January 2008 to December 2015 at the Department of Obstetrics and Gynecology of Fondazione MBBM. Only dichorionic twin pregnancies affected by selective intrauterine growth restriction (IUGR) delivering at ≥24 weeks were included in the study. RESULTS:We found that twin pregnancies with inter-twin estimated fetal weight (EFW) discordance ≥15% were significantly associated with a higher risk of preterm delivery before 32 (P=0.004) and 34 weeks (P=0.04). Similarly, twin pregnancies with inter-twin abdominal circumference (AC) discordance ≥30° centiles were associated with a higher rate of neonatal intensive care unit (NICU) admission (P=0.02), neonatal resuscitation (P=0.02) and adverse neonatal composite outcome (P=0.04). Of interest, when comparing twin pregnancies according to Doppler study, growth restricted twins had a higher rate of composite neonatal outcome and in multivariate analysis, an abnormal Doppler was an independent risk factor for this outcome. CONCLUSIONS:Our study associated growth discrepancy with specific pregnancy outcomes, according to defined cut-offs. In addition, we demonstrated that an abnormal umbilical artery Doppler is independently associated with a composite neonatal adverse outcome in growth restricted fetuses.
journal_name
J Perinat Medjournal_title
Journal of perinatal medicineauthors
Algeri P,Frigerio M,Lamanna M,Petrova PV,Cozzolino S,Incerti M,Mastrolia SA,Roncaglia N,Vergani Pdoi
10.1515/jpm-2017-0253subject
Has Abstractpub_date
2018-11-27 00:00:00pages
1028-1034issue
9eissn
0300-5577issn
1619-3997pii
/j/jpme.ahead-of-print/jpm-2017-0253/jpm-2017-0253journal_volume
46pub_type
杂志文章abstract::Erythrocyte deformability is an important determinant of microcirculation, of oxygen transport and release to the tissue. In an attempt to clarify the rheological peculiarity during pregnancy, erythrocyte deformability was measured in 10 nonpregnant controls and 10 pairs of mothers and newborns. When the hematocrit of...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1995.23.4.301
更新日期:1995-01-01 00:00:00
abstract::Changes in the technologies used in the latest generation of electronic fetal monitors has resulted generally in an improvement in the quality of the FHR data produced. However, in a number of instruments the use of inappropriate printers and signal processing has led to a degradation in the FHR trace. This may result...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1986.14.6.405
更新日期:1986-01-01 00:00:00
abstract:AIM:To determine the association, if any, between placental architecture findings assessed ultrasonographically at 22 and 36 weeks and placental histology. METHODS:There was prospective recruitment of 1011 low-risk primigravids from the antenatal clinic at the Rotunda Hospital, Dublin, Ireland. Ultrasound of the place...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2013-0015
更新日期:2013-09-01 00:00:00
abstract:UNLABELLED:Congenital cystic adenomatoid lung malformation (CCAM) is a rare disorder characterized by replacement of normal pulmonary tissue with cysts of variable size and distribution. Only sporadic cases of CCAM type III have been described that were stillborn or died in the early neonatal period. To our best knowle...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2002.068
更新日期:2002-01-01 00:00:00
abstract::Antepartum and intrapartum monitoring problems are discussed with reference to a case history of a fetal AV-block detected during the 36th week of pregnancy. CTG instruments where the internal logic criteria can be turned off are suitable for monitoring arrhythmias. During labor the direct fetal ECG permits exact diag...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1982.10.2.85
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To study maternal lipoprotein(a) levels in normal pregnancy and in pregnancy with evidence of vascular disease in the maternal uteroplacental circulation defined by Doppler ultrasound study. SAMPLES:Maternal venous blood was collected from 75 normal pregnant women and 68 pregnant women with evidence of poten...
journal_title:Journal of perinatal medicine
pub_type: 临床试验,杂志文章
doi:10.1515/JPM.2003.003
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:Idiopathic vaginal bleeding, a common complication of pregnancy, increases the risk of small-for-gestational age (SGA) neonate, preeclampsia and preterm delivery and can be the only clinical manifestation of intra-amniotic infection and/or inflammation (IAI). Placenta previa is thought to be protective agains...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2010.001
更新日期:2010-05-01 00:00:00
abstract::Serum calcium and 25-OH-D3 in mothers of newborns with craniotabes. The aim of this study was to investigate whether calcium or vitamin D balance during late pregnancy have influence on the outcome of newborn craniotabes. 27 mothers and their fullterm newborns with craniotabes in two series were studied for clinical f...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1983.11.2.127
更新日期:1983-01-01 00:00:00
abstract::Universally 4 million newborns die and another 4 million are stillborn every year. 98% of these neonatal deaths take place in the developing countries. Looking at the state of the world's newborns one can see that neonatal mortality rate is about 4-5 per 1000 in the developed countries and nearly 10 fold this in the d...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2003.060
更新日期:2003-01-01 00:00:00
abstract::Objective To derive and validate a population-specific multivariate approach for birth weight (BW) prediction based on quantitative intrapartum assessment of maternal characteristics by means of an algorithmic method in low-risk women. Methods The derivation part (n = 200) prospectively explored 10 variables to create...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2018-0347
更新日期:2019-08-27 00:00:00
abstract:AIMS:Heart rate variability (HRV) reveals information on the functional state of the autonomic nervous system (ANS). This study was initiated to assess the physiological- and maturational development of the ANS by comparing HRV data of healthy prematures with term infants. METHODS:Short-term recordings of HRV in 39 pr...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2006.058
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To compare normal ranges of ultrasonographically measured fetal nasal bone length in the second trimester between different ethnic groups. METHOD:A prospective, non-interventional study in order to establish normal ranges of fetal nasal bone length in the second trimester in a Greek population was conducted ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0296
更新日期:2016-03-01 00:00:00
abstract:AIM:To compare smooth muscle cells, type I collagen, and apoptosis of the lower uterine segment of women who had/without a prior cesarean delivery. METHODS:Alpha smooth muscle actin (α-SMA), type I collagen, and nuclear apoptosis were compared between the groups from lower uterine segment. Twenty-eight controls and 82...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2016-0347
更新日期:2018-05-24 00:00:00
abstract:AIMS:To investigate localization and concentration of adhesion molecules in the human lower uterine segment during preterm parturition. METHODS:In a prospective study biopsy specimens from the lower uterine segment of 43 patients undergoing cesarean section at 24 + 0 to 36 + 4 weeks' gestation were immunostained for i...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2001.069
更新日期:2001-01-01 00:00:00
abstract::This study was conducted to determine the risk factors of the late hyporegenerative anemia in Rh-isoimmunized infants. Data on 36 infants with rhesus hemolytic disease were analyzed. The mean gestational age and birth weight were 36 +/- 1.3 weeks and 2837 +/- 403 grams respectively. Twenty-seven infants (75%) received...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.1999.014
更新日期:1999-01-01 00:00:00
abstract::The blood flow pattern in the common umbilical vein is under normal conditions nonpulsatile in contrast to the flow in the fetal inferior vena cava. We observed pulsatile flow patterns in the common umbilical vein of fetal lambs during changes in the fetal hemodynamic equilibrium. These pulsations may influence the mi...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1986.14.1.19
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To evaluate whether uterotrophic agents increase the risk of fatal hemorrhagic brain stroke. METHODS:Between 1991 and 1992, there were 230 maternal deaths among 2,420,000 pregnant women in Japan and the causes of these deaths was investigated in 1994. Using information provided in this report, we identified ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2010.116
更新日期:2011-01-01 00:00:00
abstract::Objectives This study aimed to establish reference ranges for fetal mitral, tricuspid, and interventricular septum annular plane systolic excursions (MAPSE, TAPSE, and SAPSE) in normal pregnant women between 20 and 36 + 6 weeks of gestation. Methods This prospective and cross-sectional study included 360 low-risk sing...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2020-0002
更新日期:2020-07-28 00:00:00
abstract::Rescue cervical cerclage (RCC), also known as emergency cerclage, has long been the subject of controversy. Its use in women who have a dilated cervix has been ambivalent. RCC is often considered as a salvage measure for pregnancies which are at a high risk of severe preterm delivery (PTD) or mid-trimester miscarriage...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2017-0311
更新日期:2018-10-25 00:00:00
abstract::Anencephaly in triplets and pergonal induced pregnancies is a very rare incident. Associated cleft lip and palate has never been reported in these case. In this paper we report the first case of an anencephalic infant with cleft lip and palate in a set of pergonal-induced discordant triplet pregnancy. ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1992.20.3.241
更新日期:1992-01-01 00:00:00
abstract::Hyperphenylalaninemia in preterm neonates with heterozygosity for phenylketonuria has previously not been described. We report on a very low birth weight infant, born at a gestational age of 27+5 weeks with a birth weight of 1080 g. Due to a positive family history prenatal diagnosis for phenylketonuria was performed,...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2004.073
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:To study the normal oxygen saturation trends and fetomaternal correlates in healthy term newborns within 30 min of life born by normal vaginal delivery (NVD) and elective cesarean section (CS). MATERIALS AND METHODS:A cross-sectional study was conducted on 200 healthy term newborns born by NVD and elective ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2016-0373
更新日期:2018-02-23 00:00:00
abstract:OBJECTIVE:To assess pre-labor attitudes and post-labor experiences of the use of vacuum extraction during delivery. To seek associations between traumatic labor experience and personal preparation, physiology of labor and treatment during labor. METHODS:A total of 205 women filled in a questionnaire within five days o...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2005.068
更新日期:2005-01-01 00:00:00
abstract:AIMS:The purpose of this study was to determine whether head circumference (HC) catch-up is associated with improved neurocognitive development. DESIGN:A retrospective cohort study was conducted in 179 preterm very low birth weight (VLBW) (BW≤1500 g) infants. The infants were born in 2000-2002 and were followed to the...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2011.049
更新日期:2011-09-01 00:00:00
abstract::The neonatal outcome of 78 consecutive singleton pregnancies complicated by intrauterine growth retardation (IUGR) and gestational hypertension were compared with the outcome of 78 adequately matched pregnancies complicated by idiopathic IUGR. The rate of low (< 5) 1-minute Apgar scores was higher in infants born to h...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1993.21.3.195
更新日期:1993-01-01 00:00:00
abstract::The relationship between fetal movements and fetal heart rate accelerations was analyzed in 34 healthy near term fetuses. Periods of coincidence 2F (C2F) with a mean duration of 34 +/- 6 minutes per fetus were selected, with a total of 463 accelerations. Nineteen percent of single body movements and 71% of compilation...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1991.19.1-2.73
更新日期:1991-01-01 00:00:00
abstract::Background Little is known about the impact of peptic ulcer disease (PUD) on pregnancy. Our objective was to evaluate the effect of PUD on pregnancy and newborn outcomes. Methods A retrospective cohort study was carried out using the Healthcare Cost and Utilization Project (HCUP)-National Inpatient Sample (NIS) from t...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2019-0344
更新日期:2020-03-26 00:00:00
abstract:OBJECTIVE:To study the side effects of prolonged prostaglandin therapy especially hyperostosis and other musculoskeletal changes. METHODS:Case files of the neonates, with cyanotic heart disease, who had received prostaglandin infusion from early days of life, were reviewed. Patients with periosteal changes were identi...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2000.060
更新日期:2000-01-01 00:00:00
abstract::FHR monitoring and microanalysis of fetal blood are mutually complementary procedures, and optimal knowledge of the fetal state is achieved by making use of both, the former for the preliminary screening of all cases at risk and the latter for the purpose of deciding on obstetric management where pathological changes ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1975.3.1.53
更新日期:1975-01-01 00:00:00
abstract::We reviewed the literature on the use of inhaled nitric oxide and the influence of supplemental oxygen on bronchopulmonary dysplasia (BPD), and the role of endogenous nitric oxide-synthase, vascular endothelial growth factor, the interplay of nitric oxide and superoxide, protein nitration and the nuclear factor kappa ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2008.065
更新日期:2008-01-01 00:00:00