Abstract:
:Erythrocyte deformability is an important determinant of microcirculation, of oxygen transport and release to the tissue. In an attempt to clarify the rheological peculiarity during pregnancy, erythrocyte deformability was measured in 10 nonpregnant controls and 10 pairs of mothers and newborns. When the hematocrit of the erythrocyte suspension in dextran solution was adjusted to 35%, the deformability of fetal erythrocytes was significantly higher than maternal blood (P < 0.05), and it was almost similar to that of nonpregnant controls. Erythrocyte deformability was dependent on the hematocrit, and there was an optimal hematocrit value at which the deformability was maximal. The hematocrit, where the deformability was maximal, was a lower value (32-35%) in maternal blood, conversely, a higher value (47-50%) in cord blood than that (40-43%) in the nonpregnant. Despite decreased deformability of maternal erythrocytes, it may be compensated by reducing the hematocrit (hemodilution), preserving effective peripheral circulation including uteroplacental perfusion. On the other hand, the deformability of fetal erythrocytes may be higher in vivo at the hematocrit of 47-50% to supply oxygen to the fetal tissue even in a low oxygen condition.
journal_name
J Perinat Medjournal_title
Journal of perinatal medicineauthors
Eguchi K,Sawai T,Mizutani Ydoi
10.1515/jpme.1995.23.4.301subject
Has Abstractpub_date
1995-01-01 00:00:00pages
301-6issue
4eissn
0300-5577issn
1619-3997journal_volume
23pub_type
杂志文章abstract::Subpartal and neonatal blood gas analyses have attracted increasing interest during the past 20 years. Different studies have been carried out to investigate the causes and immediate consequences of perinatal acidosis. It was the aim of this study to examine the long term outcome of acidotic-born babies. During 16 con...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1983.11.6.278
更新日期:1983-01-01 00:00:00
abstract::The placenta secretes large amounts of the hypothelamic hormone, corticotropin releasing hormone (CRH) into the maternal and fetal circulation during pregnancy. We and other investigators have shown that during normal pregnancy, maternal plasma CRH levels begin to rise in the second trimester with a dramatic increase ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1990.18.1.39
更新日期:1990-01-01 00:00:00
abstract::Upper gastrointestinal contrast studies are frequently performed in neonates to rule out conditions such as malrotation. Low osmolality water-soluble (LOWS) contrast media are currently considered safe for use in neonates. The clinical course of a neonate with suspected necrotising enterocolitis, who deteriorated sign...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2003.080
更新日期:2003-01-01 00:00:00
abstract::Our purpose was to evaluate the hemodynamic significance of fetal inferior vena cava (IVC) flow velocity waveform indices during fetal development in relation to the diameter pulse waveform. Doppler ultrasound and a phase locked loop echo tracking system were used to measure flow velocity waveform and diameter pulse w...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2006.082
更新日期:2006-01-01 00:00:00
abstract::This study was undertaken to measure the extent of nonshivering thermogensis (NST) in brown adipose tissue of human newborns receiving routine thermal care and to examine the influence of oxygen levels at birth on the initiation of NST. Fifteen human neonates were studied in an incubator set at 31-31 degrees C. Thermo...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1997.25.5.447
更新日期:1997-01-01 00:00:00
abstract:Objectives:The purpose of this study is to follow the birth process with transperineal ultrasonography (TPU) and predict the delivery method using angle of progression (AOP). Methods:The study included 134 patients. The AOP was examined with TPU in the lithotomy position applied at 4-h intervals, not at a time of stra...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2020-0323
更新日期:2020-09-07 00:00:00
abstract::Single dose pharmacokinetics of 75 mg aspirin was investigated in two groups of ten women with clinically normal pregnancies. Eleven non-pregnant subjects in the same age were controls. In group A, gestational age was 27-30 completed weeks, and in group B, 36-39 weeks. Venous blood samples were taken before and up to ...
journal_title:Journal of perinatal medicine
pub_type: 临床试验,杂志文章
doi:10.1515/jpme.1994.22.3.205
更新日期:1994-01-01 00:00:00
abstract::Preterm infants fed fortified human milk (HM) in standard (STD) fashion grow slower than preterm formula fed infants. Recently, low protein intake has been proven to be the primary limiting factor responsible for this growth failure. The main reason of protein undernutrition despite fortification is that STD fortifica...
journal_title:Journal of perinatal medicine
pub_type: 指南,杂志文章
doi:10.1515/jpm.2010.073
更新日期:2010-05-01 00:00:00
abstract::During pregnancy the role of the cervix shifts between two opposing functions. Throughout most of gestation, the cervix is rigid and resists tension in order to maintain the products of conception inside the uterus. At term, however, cervical function changes drastically in order to accommodate stretch and delivery. T...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.1999.026
更新日期:1999-01-01 00:00:00
abstract:AIM:The present study attempts to understand the role of methylenetetrahydrofolate reductase C677T (MTHFR C677T) in recurrent pregnancy losses in North Indian women because of hyperhomocysteinemia in light of serum folate and vitamin B₁₂. METHODS:One hundred and seven women with three or more consecutive unexplained r...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2012-0252
更新日期:2013-09-01 00:00:00
abstract::A computer program was developed for the IBM PC computer to be used for maternal serum alpha fetoprotein screening (MSAFP). This program, written in BASIC, 1) maintains a data base for patients tested, 2) allows input and storage of MSAFP results, 3) calculates the gestational age dependent result in multiple of the m...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1989.17.3.221
更新日期:1989-01-01 00:00:00
abstract::Vaginal bleeding may be present in up to 30% of patients presenting with signs and symptoms of a rupture of the fetal membranes (ROM). The presence of blood may lead to false positive results with biochemical markers. The data presented in this study came from a multi-centric prospective observational clinical study t...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,多中心研究
doi:10.1515/jpm-2014-0227
更新日期:2015-07-01 00:00:00
abstract::Cytomegalovirus (CMV) is the most common cause of congenital infection in humans. Some congenitally infected infants will develop sequelae later in life, especially sensorineural hearing loss (SNHL) and mental retardation. There is no generally accepted antiviral therapy for the treatment of symptomatic congenital CMV...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2005.065
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:In cohorts of infants with proven neonatal alloimmune thrombocytopenia (NAIT) an unusual high rate of preterm infants has been reported, raising the question of whether NAIT contributes to the high rate of intracranial hemorrhage in preterm infants. METHODS:We genotyped the HPA-1-allele in a large cohort of ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2002.023
更新日期:2002-01-01 00:00:00
abstract:AIM:P-selectin is a member of selectin family (E, L- and P-selectins) which plays a crucial role in reproduction and hemostasis as well as in pathogenesis of preeclampsia. There are no regular studies on P-selectin in placenta and it is not clear whether it is present in gestational myometrium. In the present study, we...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2008.037
更新日期:2008-01-01 00:00:00
abstract::The value of testing for inherited thrombophilia in pregnancy has been debated in literature with regard to its utility in preventing adverse obstetrical outcomes or identifying women at risk for it. In this commentary, an evidence based approach is used to investigate the strength of association between thrombophilia...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0075
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:The transcatheter pelvic arterial embolization (TAE) is effective for postpartum hemorrhage (PPH). There has been a little information about the factors for ineffectiveness of TAE. The aim of this study was to determine factors associated with TAE failure for PPH. STUDY DESIGN:Fifty-five women who underwent ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2013-0242
更新日期:2014-05-01 00:00:00
abstract:AIMS:To evaluate uterine cervical consistency using a vaginal ultrasound gray-level histogram. METHODS:Vaginal ultrasound and digital examination were performed for 214 women with low-risk singleton pregnancy during 27-30(th) pregnancy week. The mean gray-level (MGL) of an ultrasound gray-level histogram, representing...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2010.079
更新日期:2010-09-01 00:00:00
abstract:AIM:Inhaled nitric oxide (iNO) is used to treat neonates with hypoxic respiratory failure (HRF). The aim of this study was to determine clinical characteristics and factors associated with non-response to iNO therapy that may assist in clinical management and weaning strategies. METHODS:Retrospective chart review. The...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2015-0210
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To construct an ultrasonographic nomogram of the fetal gastric size with gestational age in normal singleton pregnancy. PATIENTS AND METHODS:Out of 17 000 outpatient pregnant women who were admitted to our hospital, a total of 250 fetal measurements were randomly collected from routine ultrasonographic exami...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2005.060
更新日期:2005-01-01 00:00:00
abstract::The energy and redox states of placentas in newly anesthetized or sacrificed guinea pigs and sheep were compared with that of human placentas immediately after delivery. Subsequently the effect of ischemia was observed in both human and animal placentas. The influence of perfusion, using a fluid containing oxygenated ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1987.15.1.21
更新日期:1987-01-01 00:00:00
abstract::The aim of this study was to determine the neonatal outcome in women with well-characterized antiphospholipid syndrome treated during pregnancy with low-dose aspirin. We compared 38 babies born after 36 pregnancies of 33 women diagnosed as having antiphospholipid syndrome with a group of 38 control infants matched for...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1997.25.2.192
更新日期:1997-01-01 00:00:00
abstract::Results of continuous fetal tissue pH monitoring were compared to neonatal APGAR scores one minute after delivery in 81 successful tissue pH recordings. The sensitivity of the method (i.e. the ability of the method to find the low APGAR neonates) was 67 per cent using an APGAR score limit between 8 and 9 and a pH limi...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1980.8.3.158
更新日期:1980-01-01 00:00:00
abstract::The absence of one umbilical artery of single umbilical artery (SUA) is one of the most common congenital malformations in man. This vascular anomaly of the umbilical cord is frequently associated with other congenital malformations as well as some adverse perinatal events such as intrauterine growth retardation (IUGR...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1991.19.5.391
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:To study the normal oxygen saturation trends and fetomaternal correlates in healthy term newborns within 30 min of life born by normal vaginal delivery (NVD) and elective cesarean section (CS). MATERIALS AND METHODS:A cross-sectional study was conducted on 200 healthy term newborns born by NVD and elective ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2016-0373
更新日期:2018-02-23 00:00:00
abstract::The aim of the study was to compare a variety of neonatal outcome variables of growth concordant twin gestations (CT) to that of growth discordant twins (DT). Maternal and neonatal charts of live, non-anomalous twins > 25 weeks' gestation from 1984-2000 with no evidence of twin-twin transfusion syndrome were reviewed ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2003.047
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Influenza presents with increased morbidity and mortality in children ≤5 months of age. Vaccination of caregivers is indicated, but immunization rates are estimated at only 30%. The 2009 New York State Neonatal Influenza Protection Act (NIPA) mandated offering of influenza vaccine to caregivers during the po...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0248
更新日期:2014-11-01 00:00:00
abstract:AIM:The aim of this study was to review prenatally diagnosed tumors of the head and neck in the fetus and to report antenatal and postnatal outcomes. METHODS:PubMed/Medline, EMBASE/SCOPUS, Cochrane database and Google Scholar were reviewed over the last 20 years. No language or article type restriction was used. RESU...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm-2016-0074
更新日期:2017-02-01 00:00:00
abstract::The aim of this study was to evaluate whether prolonged pregnancy was associated with dangers to the fetus, and to assess the incidence of cesarean section as well as fetal distress. The outcome for mother and baby in both groups of patients with post-term pregnancies was generally good. Furthermore, the improvement o...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1995.23.3.183
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To assess mid-trimester amniotic fluid concentrations of interleukin (IL)-6, IL-8, tumor necrosis factor (TNF)-α, and lipopolysaccharide binding protein (LBP) in pregnancies with normal outcome and correlate them with gestational week (GW), parity, and fetal gender. METHODS:Cytokine concentrations were measu...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2011.041
更新日期:2011-07-01 00:00:00