当前位置： SCI文献检索 > JOURNAL OF PERINATAL MEDICINE期刊下所有文献 > Starting a regional collaborative research group for COVID-19 in pregnancy: the Southern Michigan experience.

Starting a regional collaborative research group for COVID-19 in pregnancy: the Southern Michigan experience.

Abstract：

:The outbreak of the SARS-CoV-2 elicited a surge in publications. Obstetric reports were with few exceptions characterized by small sample sizes with potentially limited generalizability. In this review, evidence suggests increased susceptibility to COVID-19 in pregnancy; common pregnancy comorbidities may help explain worse outcomes. While the risk of death is low, pregnancy may be associated with increased need for ventilation. Prematurity rates seem to be increased but may be accounted for in part by higher cesarean rates, to a large degree accounted for by elective decision to shorten the course of the labor. Though fetal/neonatal complication rates may be higher in the presence of COVID-19 infection, survival rates seem unaffected and vertical transmission is rare. As the outbreak continues in the USA with resurgence in many other western countries that achieved initial success in suppressing the virus, much remains to be learned. For example, the question related to the degree to pregnancy modifying symptomatology remains open. Currently, routine polymerase chain reaction testing remains limited by supply shortages possibly delaying diagnosis until later in the course of the disorder and thus altering the symptom complex at presentation. To add to the knowledge base, we initiated a regional COVID-19 in pregnancy collaborative observational study with a coordinating center, standardized data collection and a shared database. This was facilitated by a longstanding tradition of collaboration among regional obstetric services. Over an anticipated two-year study duration, we expect to study 400 documented and suspected COVID-19 pregnancies with time and site of services controls for cohort effect and high power to detect several adverse maternal/infant outcomes. We include a complete listing of variables in our database, which, along with our experience in setting up our regional collaborative, we hope and believe will be of use in other settings.

journal_name

J Perinat Med

journal_title

Journal of perinatal medicine

authors

Bahado-Singh R,Hassan SS,Szymanska M,Sokol RJ

doi

10.1515/jpm-2020-0399

subject

Has Abstract

pub_date

2020-11-26 00:00:00

pages

883-891

issue

eissn

0300-5577

issn

1619-3997

pii

jpm-2020-0399

journal_volume

pub_type

杂志文章,评审

在线工具

Starting a regional collaborative research group for COVID-19 in pregnancy: the Southern Michigan experience.