Incidence and birth weight characteristics of twins born to mothers aged 40 years or more compared with 35-39 years old mothers: a population study.

Abstract:

OBJECTIVE:To compare the incidence of twin births and their birth weight characteristics in mothers aged > or = 40 years with those of mothers aged 35-39 years. METHODS:We used a population-based cohort of Israeli twins delivered between 1993-98 to compare birth weight characteristics of 510 and 2102 twin pairs delivered to mothers aged > or = 40 years (cases) and 35-39 years (controls), respectively. RESULTS:The incidence of twin mothers aged 40 years or more increased 50% during the study period, ten times more than mothers aged 35-39. There were significantly more nulliparas (P < .001, OR 1.54, 95% CI 1.2, 1.9) and more para > or = 4 (P < .004, OR 1.38, 95% CI 1.1, 1.7) among older mothers. Irrespective of parity, there were no significant differences between mean twin birth weight, total twin birth weight < 3000 g, 3000-4999 g, and > or = 5000 g, and frequencies of very low birth weight neonates. CONCLUSIONS:Twin birth at the age of > or = 40 years is significantly more likely among either nulliparas or para > or = 4. Birth weight characteristics of twins delivered to mothers aged > or = 40 years are not different from those delivered to 35-39 years old mothers.

journal_name

J Perinat Med

authors

Blickstein I,Goldman RD,Mazkereth R

doi

10.1515/JPM.2001.016

keywords:

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

128-32

issue

2

eissn

0300-5577

issn

1619-3997

journal_volume

29

pub_type

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